GB766328A - Penicillin salts of esters of 4-aminosalicylic acid - Google Patents

Penicillin salts of esters of 4-aminosalicylic acid

Info

Publication number
GB766328A
GB766328A GB2050256A GB2050256A GB766328A GB 766328 A GB766328 A GB 766328A GB 2050256 A GB2050256 A GB 2050256A GB 2050256 A GB2050256 A GB 2050256A GB 766328 A GB766328 A GB 766328A
Authority
GB
United Kingdom
Prior art keywords
penicillin
esters
salt
ester
aminosalicylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2050256A
Inventor
Walter Grimme
Werner Keil
Heinrich Schmitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rheinpreussen AG fuer Bergbau und Chemie
Original Assignee
Rheinpreussen AG fuer Bergbau und Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rheinpreussen AG fuer Bergbau und Chemie filed Critical Rheinpreussen AG fuer Bergbau und Chemie
Priority to GB2050256A priority Critical patent/GB766328A/en
Publication of GB766328A publication Critical patent/GB766328A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A penicillin salt of an ester having the general formula <FORM:0766328/IV(b)/1> in which R1 and R2 are alkyl groups, each of which contains one, three or four carbon atoms, is prepared by reacting a penicillin with the appropriate ester. The penicillin is the free acid, or a salt such as sodium or potassium penicillin, and may be in any form, e.g. penicillin G, F, dihydro F or K. The ester is the free base, or a salt with an organic or inorganic acid, e.g. hydrochloric acid or N-oxide or N-hydrated oxide. Mixtures of the esters and/or penicillins may be reacted. The reaction is carried out in the presence of a solvent as in the parent Specification. The salts may be used in the purification of penicillin from, e.g. organic solvent extracts of fermentation broths. Specification 766,326 is referred to.
GB2050256A 1953-11-06 1953-11-06 Penicillin salts of esters of 4-aminosalicylic acid Expired GB766328A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2050256A GB766328A (en) 1953-11-06 1953-11-06 Penicillin salts of esters of 4-aminosalicylic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2050256A GB766328A (en) 1953-11-06 1953-11-06 Penicillin salts of esters of 4-aminosalicylic acid

Publications (1)

Publication Number Publication Date
GB766328A true GB766328A (en) 1957-01-23

Family

ID=10146951

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2050256A Expired GB766328A (en) 1953-11-06 1953-11-06 Penicillin salts of esters of 4-aminosalicylic acid

Country Status (1)

Country Link
GB (1) GB766328A (en)

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