GB2101133B - Process for preparing the acid chloride of carnitine - Google Patents
Process for preparing the acid chloride of carnitineInfo
- Publication number
- GB2101133B GB2101133B GB08218824A GB8218824A GB2101133B GB 2101133 B GB2101133 B GB 2101133B GB 08218824 A GB08218824 A GB 08218824A GB 8218824 A GB8218824 A GB 8218824A GB 2101133 B GB2101133 B GB 2101133B
- Authority
- GB
- United Kingdom
- Prior art keywords
- carnitine
- preparing
- acid chloride
- chloride
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title 1
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 title 1
- 229960004203 carnitine Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/115—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT48817/81A IT1171360B (it) | 1981-07-03 | 1981-07-03 | Procedimento per la preparazione del cloruro acido di carnitina |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2101133A GB2101133A (en) | 1983-01-12 |
| GB2101133B true GB2101133B (en) | 1985-08-14 |
Family
ID=11268676
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB08218824A Expired GB2101133B (en) | 1981-07-03 | 1982-06-29 | Process for preparing the acid chloride of carnitine |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS5815943A (el) |
| KR (1) | KR860001886B1 (el) |
| AT (1) | AT390057B (el) |
| BE (1) | BE893713A (el) |
| CA (1) | CA1186332A (el) |
| CH (1) | CH648546A5 (el) |
| DE (1) | DE3224666A1 (el) |
| DK (1) | DK154425C (el) |
| ES (1) | ES8304064A1 (el) |
| FR (1) | FR2510559B1 (el) |
| GB (1) | GB2101133B (el) |
| GR (1) | GR76546B (el) |
| IE (1) | IE53279B1 (el) |
| IL (1) | IL66251A0 (el) |
| IT (1) | IT1171360B (el) |
| LU (1) | LU84244A1 (el) |
| NL (1) | NL189666C (el) |
| SE (1) | SE448724B (el) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1190358B (it) * | 1985-05-24 | 1988-02-16 | Sclavo Spa | Procedimento per la preparazione di l-carnitina |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3940439A (en) * | 1973-11-14 | 1976-02-24 | G. D. Searle & Co. | Acid chloride synthesis |
| IT1116037B (it) * | 1979-04-23 | 1986-02-10 | Sigma Tau Ind Farmaceuti | Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico |
| DE2943433A1 (de) * | 1979-10-26 | 1981-05-07 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von carbonsaeurehalogeniden |
-
1981
- 1981-07-03 IT IT48817/81A patent/IT1171360B/it active
-
1982
- 1982-06-24 CH CH3884/82A patent/CH648546A5/it not_active IP Right Cessation
- 1982-06-25 IE IE1524/82A patent/IE53279B1/en not_active IP Right Cessation
- 1982-06-29 GB GB08218824A patent/GB2101133B/en not_active Expired
- 1982-06-30 BE BE0/208502A patent/BE893713A/fr not_active IP Right Cessation
- 1982-06-30 DK DK295482A patent/DK154425C/da not_active IP Right Cessation
- 1982-06-30 LU LU84244A patent/LU84244A1/fr unknown
- 1982-06-30 CA CA000406463A patent/CA1186332A/en not_active Expired
- 1982-07-01 KR KR8202945A patent/KR860001886B1/ko active
- 1982-07-01 DE DE19823224666 patent/DE3224666A1/de active Granted
- 1982-07-01 GR GR68615A patent/GR76546B/el unknown
- 1982-07-02 ES ES513658A patent/ES8304064A1/es not_active Expired
- 1982-07-02 FR FR8211685A patent/FR2510559B1/fr not_active Expired
- 1982-07-02 SE SE8204117A patent/SE448724B/sv not_active IP Right Cessation
- 1982-07-02 JP JP57116084A patent/JPS5815943A/ja active Granted
- 1982-07-02 AT AT0257382A patent/AT390057B/de not_active IP Right Cessation
- 1982-07-02 NL NLAANVRAGE8202677,A patent/NL189666C/xx not_active IP Right Cessation
- 1982-07-07 IL IL66251A patent/IL66251A0/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL189666B (nl) | 1993-01-18 |
| GB2101133A (en) | 1983-01-12 |
| ATA257382A (de) | 1989-08-15 |
| ES513658A0 (es) | 1983-03-01 |
| FR2510559B1 (fr) | 1986-05-09 |
| DE3224666A1 (de) | 1983-01-20 |
| DK154425B (da) | 1988-11-14 |
| KR860001886B1 (ko) | 1986-10-24 |
| CH648546A5 (it) | 1985-03-29 |
| IT8148817A0 (it) | 1981-07-03 |
| NL8202677A (nl) | 1983-02-01 |
| DK154425C (da) | 1989-04-10 |
| SE448724B (sv) | 1987-03-16 |
| IL66251A0 (en) | 1982-11-30 |
| LU84244A1 (fr) | 1983-01-20 |
| FR2510559A1 (fr) | 1983-02-04 |
| GR76546B (el) | 1984-08-10 |
| AT390057B (de) | 1990-03-12 |
| ES8304064A1 (es) | 1983-03-01 |
| JPH0244300B2 (el) | 1990-10-03 |
| CA1186332A (en) | 1985-04-30 |
| NL189666C (nl) | 1993-06-16 |
| DE3224666C2 (el) | 1991-01-24 |
| SE8204117D0 (sv) | 1982-07-02 |
| IT1171360B (it) | 1987-06-10 |
| BE893713A (fr) | 1982-10-18 |
| KR840000475A (ko) | 1984-02-22 |
| IE821524L (en) | 1983-01-03 |
| JPS5815943A (ja) | 1983-01-29 |
| DK295482A (da) | 1983-01-04 |
| IE53279B1 (en) | 1988-09-28 |
| SE8204117L (sv) | 1983-01-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19930629 |