ES8304064A1 - "un procedimiento para producir cloruro de acido de carnitina". - Google Patents
"un procedimiento para producir cloruro de acido de carnitina".Info
- Publication number
- ES8304064A1 ES8304064A1 ES513658A ES513658A ES8304064A1 ES 8304064 A1 ES8304064 A1 ES 8304064A1 ES 513658 A ES513658 A ES 513658A ES 513658 A ES513658 A ES 513658A ES 8304064 A1 ES8304064 A1 ES 8304064A1
- Authority
- ES
- Spain
- Prior art keywords
- carnitine
- acid chloride
- preparing
- hours
- crotonylbetaine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004203 carnitine Drugs 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- PHIQHXFUZVPYII-UHFFFAOYSA-N carnitine Chemical compound C[N+](C)(C)CC(O)CC([O-])=O PHIQHXFUZVPYII-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/115—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO PARA PRODUCIR CLORURO DE ACIDO DE CARNITINA. SE CLORA CARNITINA POR REACCION DE ESTA CON UN AGENTE CLORANTE ELEGIDO DE ENTRE CLORURO DE TIONILO, ETER DICLOROMETILICO Y CLORURO DE OXALILO, A LA TEMPERATURA AMBIENTE, SIENDO EL TIEMPO DE ESTANCIA EN REACCION EL COMPRENDIDO ENTRE 1 HORA Y 12 HORAS. LA REACCION SE DEBE LLEVAR A CABO MANTENIENDO UNA RELACION MOLAR CARNITINA/AGENTE CLORANTE COMPRENDIDA ENTRE 1:1 Y 1:3. SE UTILIZA COMO INTERMEDIARIO PARA LA PREPARACION DE DERIVADOS DE CARNITINA, TAL COMO ESTERES Y AMIDAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT48817/81A IT1171360B (it) | 1981-07-03 | 1981-07-03 | Procedimento per la preparazione del cloruro acido di carnitina |
Publications (2)
Publication Number | Publication Date |
---|---|
ES513658A0 ES513658A0 (es) | 1983-03-01 |
ES8304064A1 true ES8304064A1 (es) | 1983-03-01 |
Family
ID=11268676
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES513658A Expired ES8304064A1 (es) | 1981-07-03 | 1982-07-02 | "un procedimiento para producir cloruro de acido de carnitina". |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS5815943A (es) |
KR (1) | KR860001886B1 (es) |
AT (1) | AT390057B (es) |
BE (1) | BE893713A (es) |
CA (1) | CA1186332A (es) |
CH (1) | CH648546A5 (es) |
DE (1) | DE3224666A1 (es) |
DK (1) | DK154425C (es) |
ES (1) | ES8304064A1 (es) |
FR (1) | FR2510559B1 (es) |
GB (1) | GB2101133B (es) |
GR (1) | GR76546B (es) |
IE (1) | IE53279B1 (es) |
IL (1) | IL66251A0 (es) |
IT (1) | IT1171360B (es) |
LU (1) | LU84244A1 (es) |
NL (1) | NL189666C (es) |
SE (1) | SE448724B (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1190358B (it) * | 1985-05-24 | 1988-02-16 | Sclavo Spa | Procedimento per la preparazione di l-carnitina |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3940439A (en) * | 1973-11-14 | 1976-02-24 | G. D. Searle & Co. | Acid chloride synthesis |
IT1116037B (it) * | 1979-04-23 | 1986-02-10 | Sigma Tau Ind Farmaceuti | Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico |
DE2943433A1 (de) * | 1979-10-26 | 1981-05-07 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von carbonsaeurehalogeniden |
-
1981
- 1981-07-03 IT IT48817/81A patent/IT1171360B/it active
-
1982
- 1982-06-24 CH CH3884/82A patent/CH648546A5/it not_active IP Right Cessation
- 1982-06-25 IE IE1524/82A patent/IE53279B1/en not_active IP Right Cessation
- 1982-06-29 GB GB08218824A patent/GB2101133B/en not_active Expired
- 1982-06-30 BE BE0/208502A patent/BE893713A/fr not_active IP Right Cessation
- 1982-06-30 DK DK295482A patent/DK154425C/da not_active IP Right Cessation
- 1982-06-30 LU LU84244A patent/LU84244A1/fr unknown
- 1982-06-30 CA CA000406463A patent/CA1186332A/en not_active Expired
- 1982-07-01 KR KR8202945A patent/KR860001886B1/ko active
- 1982-07-01 DE DE19823224666 patent/DE3224666A1/de active Granted
- 1982-07-01 GR GR68615A patent/GR76546B/el unknown
- 1982-07-02 ES ES513658A patent/ES8304064A1/es not_active Expired
- 1982-07-02 FR FR8211685A patent/FR2510559B1/fr not_active Expired
- 1982-07-02 SE SE8204117A patent/SE448724B/sv not_active IP Right Cessation
- 1982-07-02 JP JP57116084A patent/JPS5815943A/ja active Granted
- 1982-07-02 AT AT0257382A patent/AT390057B/de not_active IP Right Cessation
- 1982-07-02 NL NLAANVRAGE8202677,A patent/NL189666C/xx not_active IP Right Cessation
- 1982-07-07 IL IL66251A patent/IL66251A0/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NL189666B (nl) | 1993-01-18 |
GB2101133A (en) | 1983-01-12 |
GB2101133B (en) | 1985-08-14 |
ATA257382A (de) | 1989-08-15 |
ES513658A0 (es) | 1983-03-01 |
FR2510559B1 (fr) | 1986-05-09 |
DE3224666A1 (de) | 1983-01-20 |
DK154425B (da) | 1988-11-14 |
KR860001886B1 (ko) | 1986-10-24 |
CH648546A5 (it) | 1985-03-29 |
IT8148817A0 (it) | 1981-07-03 |
NL8202677A (nl) | 1983-02-01 |
DK154425C (da) | 1989-04-10 |
SE448724B (sv) | 1987-03-16 |
IL66251A0 (en) | 1982-11-30 |
LU84244A1 (fr) | 1983-01-20 |
FR2510559A1 (fr) | 1983-02-04 |
GR76546B (es) | 1984-08-10 |
AT390057B (de) | 1990-03-12 |
JPH0244300B2 (es) | 1990-10-03 |
CA1186332A (en) | 1985-04-30 |
NL189666C (nl) | 1993-06-16 |
DE3224666C2 (es) | 1991-01-24 |
SE8204117D0 (sv) | 1982-07-02 |
IT1171360B (it) | 1987-06-10 |
BE893713A (fr) | 1982-10-18 |
KR840000475A (ko) | 1984-02-22 |
IE821524L (en) | 1983-01-03 |
JPS5815943A (ja) | 1983-01-29 |
DK295482A (da) | 1983-01-04 |
IE53279B1 (en) | 1988-09-28 |
SE8204117L (sv) | 1983-01-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS55162401A (en) | Method of recovering concentrated hydrochloric acid from rough product resulting from acid hydrolysis of cellulose | |
DE3782297D1 (de) | Herstellung von antiperspiranten. | |
ES423325A1 (es) | Procedimiento para la obtencion de fluoruro de calcio sin- tetico. | |
ES8304064A1 (es) | "un procedimiento para producir cloruro de acido de carnitina". | |
GB1491413A (en) | L-3-(3,4-dihydroxyphenyl)-2-methyl-alanine peptides | |
UA8020A1 (uk) | Спосіб отримання 2,4-діхлор-5-фторбензойної кислоти | |
ATE19868T1 (de) | Herstellung von natriumsalicylat. | |
ES8105304A1 (es) | Procedimiento para la obtencion de acido cianurico puro | |
ES477086A1 (es) | Procedimiento para la preparacion de 4-metil-5-hidroximetil-imidazol. | |
IT8022565A0 (it) | Procedimento per la produzione di acido cloridico ed amoniaca. | |
GB2098218B (en) | Micorbial production of 9-hydroxy-3-oxo-4,17(20)-pregnadiene-20-carboxylic acid | |
IT8019441A0 (it) | Cella per l'elettrolisi di acido cloridrico. | |
DE3572171D1 (en) | Theophylline-7-acetic acid ester of d,l-trans-sobrerol having mucosecretolytic-fluidizing and antibronchospastic activity, a process for its preparation and pharmaceutical compositions thereof | |
ES8602610A1 (es) | Procedimiento para la preparacion de sales de carnitina del acido alfa-glucoso-1-fosforico | |
JPS52131510A (en) | Preparation of 6-methyl-5-heptene-2-one | |
GB1464832A (en) | Process for the preparation of a-oxothiodimethylamides | |
IE36829B1 (en) | Process for the preparation of penicillamine | |
DE2961478D1 (en) | Process for the preparation of 2,4-dinitrophenyl urea | |
SU1045566A1 (ru) | Хлорангидрид 3,4-дициано - 4′- -карбоксидифенилоксида в качестве полупродукта для синтеза тетранитрилов ароматических тетракарбоновых кислот, тетранитрилы ароматических тетракарбоновых кислот как мономеры для синтеза полигексазоцикланов и полигексазоцикланы как материалы для электропроводящих покрытий | |
ES410734A1 (es) | Procedimiento para la obtencion del pamoato de butacaina. | |
JPS57209258A (en) | 1-amino-cyclopropane carboxylic acid derivatives, manufacture and use as plant growth regulant | |
JPS5775953A (en) | Novel derivative of 2-hydroxyoxanilic acid | |
DE3560019D1 (en) | Process for the production of diphenyl-4,4'-disulfonic acid | |
Ifeanyi | Neuraminidase as a virulence factor of Pasteurella multocida | |
JPS57169487A (en) | Production of imidazoledicarboxylic acid derivative |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970303 |