GB201810668D0 - New compounds - Google Patents
New compoundsInfo
- Publication number
- GB201810668D0 GB201810668D0 GBGB1810668.2A GB201810668A GB201810668D0 GB 201810668 D0 GB201810668 D0 GB 201810668D0 GB 201810668 A GB201810668 A GB 201810668A GB 201810668 D0 GB201810668 D0 GB 201810668D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- new compounds
- compounds
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1810668.2A GB201810668D0 (en) | 2018-06-28 | 2018-06-28 | New compounds |
| CA3104237A CA3104237A1 (en) | 2018-06-28 | 2019-06-28 | 4-substituted phenyl-1,3,5-triazine derivatives as modulators of trk receptors |
| PCT/GB2019/051853 WO2020002950A1 (en) | 2018-06-28 | 2019-06-28 | 4-substituted phenyl-1,3,5-triazine derivatives as modulators of trk receptors |
| CN201980045116.8A CN112513032B (zh) | 2018-06-28 | 2019-06-28 | 作为trk受体的调节剂的4-取代的苯基-1,3,5-三嗪衍生物 |
| US17/255,642 US11840524B2 (en) | 2018-06-28 | 2019-06-28 | 4-substituted phenyl-1,3,5-triazine derivatives as modulators of TrK receptors |
| EP19739692.2A EP3814335B1 (en) | 2018-06-28 | 2019-06-28 | 4-substituted phenyl-1,3,5-triazine derivatives as modulators of trk receptors |
| KR1020217000575A KR20210024531A (ko) | 2018-06-28 | 2019-06-28 | Trk 수용체의 조절제로서의 4-치환된 페닐-1,3,5-트리아진 유도체 |
| BR112020026619-1A BR112020026619A2 (pt) | 2018-06-28 | 2019-06-28 | Composto, método para tratar e/ou prevenir uma doença que apresenta sinalização prejudicada de neurotrofinas e/ou outros fatores trópicos, uso de um composto, produto de combinação, kit de partes, e, processo para a preparação de um composto |
| ES19739692T ES2935183T3 (es) | 2018-06-28 | 2019-06-28 | Derivados de fenil-1,3,5-triazina 4-sustituidos como moduladores de los receptores TRK |
| JP2020570716A JP7510358B2 (ja) | 2018-06-28 | 2019-06-28 | Trk受容体の調節剤としての4-置換フェニル-1,3,5-トリアジン誘導体 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1810668.2A GB201810668D0 (en) | 2018-06-28 | 2018-06-28 | New compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB201810668D0 true GB201810668D0 (en) | 2018-08-15 |
Family
ID=63143731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB1810668.2A Ceased GB201810668D0 (en) | 2018-06-28 | 2018-06-28 | New compounds |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11840524B2 (enExample) |
| EP (1) | EP3814335B1 (enExample) |
| JP (1) | JP7510358B2 (enExample) |
| KR (1) | KR20210024531A (enExample) |
| CN (1) | CN112513032B (enExample) |
| BR (1) | BR112020026619A2 (enExample) |
| CA (1) | CA3104237A1 (enExample) |
| ES (1) | ES2935183T3 (enExample) |
| GB (1) | GB201810668D0 (enExample) |
| WO (1) | WO2020002950A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2020008816A (es) | 2018-02-26 | 2020-09-28 | AlzeCure Pharma AB | Derivados de triazina para el tratamiento de enfermedades relacionadas con neurotrofinas. |
| GB201912404D0 (en) * | 2019-08-29 | 2019-10-16 | AlzeCure Pharma AB | New compounds |
| CA3180846A1 (en) * | 2020-06-03 | 2021-12-09 | Dana-Farber Cancer Institute, Inc. | Inhibitors of transcriptional enhanced associate domain (tead) and uses thereof |
| WO2025232990A1 (en) | 2024-05-09 | 2025-11-13 | AlzeCure Pharma AB | Triazinone derivatives for use in the treatment of inflammation |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2246109A1 (de) | 1972-09-20 | 1974-03-28 | Bayer Ag | 1-(4-phenoxy-phenyl)-1,3,5-triazinderivate, ein verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE2313721A1 (de) | 1973-03-20 | 1974-10-03 | Bayer Ag | Neue 1-phenylsubstituierte 1,3,5triazine, verfahren zu ihrer herstellung, sowie ihre verwendung als arzneimittel |
| DE2413722C3 (de) * | 1974-03-21 | 1982-04-08 | Bayer Ag, 5090 Leverkusen | Neue 1-(4-Phenoxy-phenyl)-1,3,5-triazin-Derivate, ein Verfahren zu ihrer Herstellung sowie ihre Anwendung als Arzneimittel |
| DE2718799A1 (de) | 1977-04-27 | 1978-11-09 | Bayer Ag | 1-(4-phenoxy-phenyl)-1,3,5-triazin- derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel und wachstumsfoerderer |
| CA1185974A (en) | 1981-12-03 | 1985-04-23 | Adolf Parg | 1,3,5-triazinones and their use for controlling undesirable plant growth |
| DE3314739A1 (de) | 1983-04-23 | 1984-10-25 | Bayer Ag, 5090 Leverkusen | 1-(4-(4-(fluoralkylmethylthio- oder -sulfinyl- oder -sulfonyl-)phenoxy) phenyl)-1,3,5-triazin-2,4,6(1h,3h,5h)-trione, verfahren zu ihrer herstellung und ihre verwendung als coccidiosemittel |
| DE3408768A1 (de) | 1984-03-09 | 1985-09-12 | Bayer Ag, 5090 Leverkusen | Immunstimulierende mittel |
| DE3516631A1 (de) | 1985-05-09 | 1986-11-13 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 3-methyl-1,3,5-triazintrionen |
| DE3516632A1 (de) | 1985-05-09 | 1986-11-13 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 1,3,5-triazintrionen |
| DE3703105A1 (de) | 1987-02-03 | 1988-08-11 | Bayer Ag | Mittel gegen protozoen bei insekten |
| DE3810080A1 (de) | 1988-03-25 | 1989-10-05 | Bayer Ag | Trisubstituierte 1,3,5-triazin-2,4,6-trione |
| DE3814323A1 (de) | 1988-04-28 | 1989-11-09 | Hoechst Ag | Wasserloesliche zubereitungen von coccidiostatica |
| US4933341A (en) | 1988-10-08 | 1990-06-12 | Bayer Aktiengesellschaft | Substituted 1,3,5-triazinetriones, for use against parasitic protozoa |
| DE4000624A1 (de) | 1990-01-11 | 1991-07-18 | Bayer Ag | Fungizide verwendung von trisubstituierten 1,3,5-triazin-2,4,6-trionen, neue trisubstituierte 1,3,5-triazin-2,4,6-trione und verfahren zu ihrer herstellung |
| DE4329096A1 (de) | 1993-08-30 | 1995-03-02 | Bayer Ag | Heterocyclylbenzoheterocyclen |
| US5604180A (en) | 1995-06-02 | 1997-02-18 | Crews, Jr.; Alvin D. | 3-(3-aryloxyphenyl)-1 (substituted methyl)-s-triazine-2,4,6-oxo or thiotrione herbicidal agents |
| US5519133A (en) | 1995-06-02 | 1996-05-21 | American Cyanamid Co. | 3-(3-aryloxyphenyl)-1-(substituted methyl)-s-triazine-2,4,6-oxo or thiotrione herbicidal agents |
| US5726126A (en) | 1995-06-02 | 1998-03-10 | American Cyanamid Company | 1-(3-heterocyclyphenyl)-S-triazine-2,6,6-oxo or thiotrione herbicidal agents |
| CZ146296A3 (en) | 1995-06-02 | 1997-04-16 | American Cyanamid Co | 3-(3-aryloxyphenyl)-1-(substituted methyl)-s-triazine-2,4,6-oxo or thiotriones, process of their preparation and herbicidal agents |
| US5679791A (en) | 1996-07-25 | 1997-10-21 | American Cyanamid Company | 1-(3-heterocyclylphenyl)-s-triazine-2,4,6-oxo or thiotrione herbicidal agents |
| HK1043019B (zh) | 1998-10-08 | 2005-05-13 | 高新研究公司 | 用於预防和治疗原虫病的组合物和方法 |
| CA2356181A1 (en) | 1998-12-22 | 2000-06-29 | Bayer Corporation | Triazineone compounds for treating diseases due to sarcocystis, neospora and toxoplasma |
| DE19937500A1 (de) | 1999-08-09 | 2001-02-15 | Bayer Ag | Substituierte Heterocyclylbenzofurane |
| DE19958388A1 (de) | 1999-12-03 | 2001-06-07 | Bayer Ag | Triazinonverbindungen zur Behandlung von durch den Befall mit parasitischen Protozoen bedingten Krankheiten |
| US6444615B1 (en) | 2000-04-18 | 2002-09-03 | Dow Agrosciences Llc | Herbicidal imidazolidinetrione and thioxo-imidazolidinediones |
| DE10034800A1 (de) | 2000-07-18 | 2002-01-31 | Bayer Ag | Substituierte Benzostickstoffheterocyclen |
| DE10040174A1 (de) | 2000-08-17 | 2002-02-28 | Bayer Ag | Verwendung von Triazintrion-Sulfonen zur Bekämpfung von Coccidiosen |
| DE10040110A1 (de) | 2000-08-17 | 2002-02-28 | Bayer Ag | Verwendung von Triazintrion-Sulfoxiden zur Bekämpfung von Coccidiosen |
| AU2002324586B2 (en) | 2001-08-02 | 2008-04-24 | Neurocrine Biosciences, Inc. | 1,3,5-triazine-2,4,6-triones, preparation and use as gonadotropin-releasing hormone receptor antagonists |
| US6861523B2 (en) | 2002-02-08 | 2005-03-01 | Torrey Pines Institute For Molecular Studies | 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries |
| PL372418A1 (en) | 2002-05-30 | 2005-07-25 | Solvay Pharmaceuticals B.V. | 1,3,5-triazine derivatives as ligands for human adenosine-a3 receptors |
| JP2005534681A (ja) | 2002-07-15 | 2005-11-17 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | キナーゼ阻害剤としてのトキソフラビンの3−フラニル類似物 |
| DE102006038292A1 (de) | 2006-08-16 | 2008-02-21 | Bayer Healthcare Ag | Transdermale Anwendung von Triazinen zur Bekämpfung von Coccidien-Infektionen |
| WO2008148008A1 (en) * | 2007-05-23 | 2008-12-04 | Emory University | High throughput bioassay for identifying selective trka receptor agonists, and gambogic amide, a selective trka agonist with neuroprotective activity |
| WO2011150347A2 (en) * | 2010-05-28 | 2011-12-01 | Pharmatrophix | Non-peptide bdnf neurotrophin mimetics |
| KR20150134369A (ko) | 2013-03-15 | 2015-12-01 | 파마트로픽스 인코포레이티드 | 비펩타이드 bdnf 뉴로트로핀 모방체 |
| CA2935270A1 (en) | 2014-01-20 | 2015-07-23 | F. Hoffmann-La Roche Ag | N-phenyl-lactam derivatives capable of stimulating neurogenesis and their use in the treatment of neurological disorders |
| CN107249349B (zh) | 2014-12-10 | 2021-06-08 | 马斯公司 | 用于调节味觉受体的方法 |
| BR112019012709A2 (pt) | 2016-12-21 | 2019-11-26 | AlzeCure Pharma AB | composto, método para tratar e/ou prevenir uma doença distinguida por sinalização deficiente de neurotrofinas e/ou outros fatores tróficos, uso de um composto, composição farmacêutica, produto de combinação, kit de peças, e, processos para preparação de um composto e de uma composição farmacêutica. |
| MX2020008816A (es) | 2018-02-26 | 2020-09-28 | AlzeCure Pharma AB | Derivados de triazina para el tratamiento de enfermedades relacionadas con neurotrofinas. |
| GB201810669D0 (en) | 2018-06-28 | 2018-08-15 | Stiftelsen Alzecure | New compounds |
| GB201912404D0 (en) | 2019-08-29 | 2019-10-16 | AlzeCure Pharma AB | New compounds |
-
2018
- 2018-06-28 GB GBGB1810668.2A patent/GB201810668D0/en not_active Ceased
-
2019
- 2019-06-28 JP JP2020570716A patent/JP7510358B2/ja active Active
- 2019-06-28 CN CN201980045116.8A patent/CN112513032B/zh active Active
- 2019-06-28 CA CA3104237A patent/CA3104237A1/en active Pending
- 2019-06-28 BR BR112020026619-1A patent/BR112020026619A2/pt not_active Application Discontinuation
- 2019-06-28 US US17/255,642 patent/US11840524B2/en active Active
- 2019-06-28 KR KR1020217000575A patent/KR20210024531A/ko active Pending
- 2019-06-28 WO PCT/GB2019/051853 patent/WO2020002950A1/en not_active Ceased
- 2019-06-28 EP EP19739692.2A patent/EP3814335B1/en active Active
- 2019-06-28 ES ES19739692T patent/ES2935183T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA3104237A1 (en) | 2020-01-02 |
| ES2935183T3 (es) | 2023-03-02 |
| US20210371402A1 (en) | 2021-12-02 |
| WO2020002950A1 (en) | 2020-01-02 |
| CN112513032A (zh) | 2021-03-16 |
| EP3814335A1 (en) | 2021-05-05 |
| US11840524B2 (en) | 2023-12-12 |
| KR20210024531A (ko) | 2021-03-05 |
| CN112513032B (zh) | 2024-07-02 |
| JP7510358B2 (ja) | 2024-07-03 |
| BR112020026619A2 (pt) | 2021-03-30 |
| JP2021529168A (ja) | 2021-10-28 |
| EP3814335B1 (en) | 2022-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| COOA | Change in applicant's name or ownership of the application |
Owner name: ALZECURE PHARMA AB Free format text: FORMER OWNER: STIFTELSEN ALZECURE |
|
| AT | Applications terminated before publication under section 16(1) |