GB1538227A - 16,16-disubstituted steroids of the androstene series - Google Patents
16,16-disubstituted steroids of the androstene seriesInfo
- Publication number
- GB1538227A GB1538227A GB11819/75A GB1181975A GB1538227A GB 1538227 A GB1538227 A GB 1538227A GB 11819/75 A GB11819/75 A GB 11819/75A GB 1181975 A GB1181975 A GB 1181975A GB 1538227 A GB1538227 A GB 1538227A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carbon atoms
- radicals
- radical
- alkyl radical
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Priority Applications (24)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB11819/75A GB1538227A (en) | 1975-03-21 | 1975-03-21 | 16,16-disubstituted steroids of the androstene series |
IE412/76A IE42308B1 (en) | 1975-03-21 | 1976-03-01 | 16, 16-disubstituted steroids of the androstene series |
IL49132A IL49132A (en) | 1975-03-21 | 1976-03-02 | 16,1l-disubstituted androst-4-en-3-ones,their preparation and pharmaceutical compositions containing them |
IL58505A IL58505A (en) | 1975-03-21 | 1976-03-02 | 16,1l-disubstituted androst-5-ene derivatives and their preparation |
DE2610497A DE2610497C2 (de) | 1975-03-21 | 1976-03-12 | In 16-Stellung disubstituierte 3- Ketosteroide, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
FR7607328A FR2304345A1 (fr) | 1975-03-21 | 1976-03-15 | Derives des steroides |
AT191376A AT357700B (de) | 1975-03-21 | 1976-03-16 | Verfahren zur herstellung von neuen in 16- stellung disubstituierten 3-ketosteroiden |
SE7603410A SE7603410L (sv) | 1975-03-21 | 1976-03-18 | Farmaceutiskt aktiva foreningar |
BE165323A BE839751A (fr) | 1975-03-21 | 1976-03-18 | Derives de steroides |
CA248,260A CA1069498A (en) | 1975-03-21 | 1976-03-19 | Pharmaceutically active steroids |
DK123476A DK143757C (da) | 1975-03-21 | 1976-03-19 | Analogifremgangsmaade til fremstilling af 16,16-disubstituerede 3-oxoandrostener |
AU12207/76A AU501246B2 (en) | 1975-03-21 | 1976-03-19 | 16, 16 disubstituted androstenes |
JP51030741A JPS51118756A (en) | 1975-03-21 | 1976-03-19 | Novel steroids * pharmaceutical composition containing same and preparation thereof |
NLAANVRAGE7602949,A NL184111C (nl) | 1975-03-21 | 1976-03-19 | Werkwijze voor het bereiden van androstenonen en van farmaceutische preparaten welke deze bevatten. |
CH354376A CH621560A5 (en) | 1975-03-21 | 1976-03-22 | Process for the preparation of 3-ketosteroids disubstituted in position 16 |
ZA761324A ZA761324B (en) | 1975-03-21 | 1976-04-04 | Pharmaceutically active compounds |
CA306,343A CA1069496A (en) | 1975-03-21 | 1978-06-28 | Intermediates for pharmaceutically active steroids |
CH228479A CH631996A5 (en) | 1975-03-21 | 1979-03-09 | Process for the preparation of 16-disubstituted steroids |
SE7902256A SE7902256L (sv) | 1975-03-21 | 1979-03-13 | Nya foreningar |
AT398879A AT368524B (de) | 1975-03-21 | 1979-05-31 | Verfahren zur herstellung von neuen in 16-stellung disubstituierten 3-ketosteroiden |
IL58505A IL58505A0 (en) | 1975-03-21 | 1979-10-19 | 16,16-disubstituted androst-5-ene derivatives and their preparation |
FR8004184A FR2445340A1 (fr) | 1975-03-21 | 1980-02-26 | Intermediaires pour la preparation de derives des steroides ayant une activite pharmaceutique |
DK102480A DK102480A (da) | 1975-03-21 | 1980-03-10 | Mellemprodukter til fremstilling af 16,16-dialkylsteroider |
JP60291811A JPS61178920A (ja) | 1975-03-21 | 1985-12-24 | 4−エン−16,16−ジ置換−3−オンステロイドを含有する医薬組成物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB11819/75A GB1538227A (en) | 1975-03-21 | 1975-03-21 | 16,16-disubstituted steroids of the androstene series |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1538227A true GB1538227A (en) | 1979-01-10 |
Family
ID=9993275
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB11819/75A Expired GB1538227A (en) | 1975-03-21 | 1975-03-21 | 16,16-disubstituted steroids of the androstene series |
Country Status (15)
Country | Link |
---|---|
JP (2) | JPS51118756A (sv) |
AT (1) | AT357700B (sv) |
AU (1) | AU501246B2 (sv) |
BE (1) | BE839751A (sv) |
CA (1) | CA1069498A (sv) |
CH (2) | CH621560A5 (sv) |
DE (1) | DE2610497C2 (sv) |
DK (1) | DK143757C (sv) |
FR (2) | FR2304345A1 (sv) |
GB (1) | GB1538227A (sv) |
IE (1) | IE42308B1 (sv) |
IL (2) | IL49132A (sv) |
NL (1) | NL184111C (sv) |
SE (2) | SE7603410L (sv) |
ZA (1) | ZA761324B (sv) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992005763A1 (en) * | 1990-10-04 | 1992-04-16 | Beecham Group Plc | Composition containing steroid derivatives |
WO1992007586A1 (en) * | 1990-10-31 | 1992-05-14 | Beecham Group Plc | Topical composition with retinoid penetration enhancer |
WO1993017687A1 (en) * | 1992-03-10 | 1993-09-16 | Smithkline Beecham Plc | Topical compositions containing steroids |
WO2003051903A1 (fr) * | 2001-12-19 | 2003-06-26 | Chugai Seiyaku Kabushiki Kaisha | Derive de l'androstane renfermant un substituant en position 7 et 17 |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1602960A (en) * | 1977-05-25 | 1981-11-18 | Beecham Group Ltd | Process for preparing 16,16-disubstituted steroids of the androstene series |
DE2943778A1 (de) * | 1979-10-26 | 1981-05-07 | Schering Ag Berlin Und Bergkamen, 1000 Berlin | 17 (alpha) -alkylsteroide, diese enthaltende praeparate sowie verfahren zu ihrer herstellung |
DE3514272A1 (de) * | 1985-04-17 | 1986-10-23 | Schering AG, 1000 Berlin und 4709 Bergkamen | Dermatica |
JPS63300153A (ja) * | 1987-05-29 | 1988-12-07 | 日本碍子株式会社 | 建築用ほうろうパネル |
CN108558975B (zh) * | 2018-04-26 | 2021-03-02 | 昆明理工大学 | 12β-羟基-雄甾4,14-二烯-16-酮类化合物及其应用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3853926A (en) * | 1973-05-29 | 1974-12-10 | Searle & Co | 17{62 -hydroxy-16,16-dimethylester-4-en-3-one |
-
1975
- 1975-03-21 GB GB11819/75A patent/GB1538227A/en not_active Expired
-
1976
- 1976-03-01 IE IE412/76A patent/IE42308B1/en unknown
- 1976-03-02 IL IL49132A patent/IL49132A/xx unknown
- 1976-03-12 DE DE2610497A patent/DE2610497C2/de not_active Expired
- 1976-03-15 FR FR7607328A patent/FR2304345A1/fr active Granted
- 1976-03-16 AT AT191376A patent/AT357700B/de not_active IP Right Cessation
- 1976-03-18 BE BE165323A patent/BE839751A/xx not_active IP Right Cessation
- 1976-03-18 SE SE7603410A patent/SE7603410L/sv not_active Application Discontinuation
- 1976-03-19 DK DK123476A patent/DK143757C/da active
- 1976-03-19 JP JP51030741A patent/JPS51118756A/ja active Granted
- 1976-03-19 AU AU12207/76A patent/AU501246B2/en not_active Expired
- 1976-03-19 CA CA248,260A patent/CA1069498A/en not_active Expired
- 1976-03-19 NL NLAANVRAGE7602949,A patent/NL184111C/xx not_active IP Right Cessation
- 1976-03-22 CH CH354376A patent/CH621560A5/de not_active IP Right Cessation
- 1976-04-04 ZA ZA761324A patent/ZA761324B/xx unknown
-
1979
- 1979-03-09 CH CH228479A patent/CH631996A5/de not_active IP Right Cessation
- 1979-03-13 SE SE7902256A patent/SE7902256L/sv not_active Application Discontinuation
- 1979-10-19 IL IL58505A patent/IL58505A0/xx unknown
-
1980
- 1980-02-26 FR FR8004184A patent/FR2445340A1/fr active Granted
-
1985
- 1985-12-24 JP JP60291811A patent/JPS61178920A/ja active Granted
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992005763A1 (en) * | 1990-10-04 | 1992-04-16 | Beecham Group Plc | Composition containing steroid derivatives |
WO1992007586A1 (en) * | 1990-10-31 | 1992-05-14 | Beecham Group Plc | Topical composition with retinoid penetration enhancer |
WO1993017687A1 (en) * | 1992-03-10 | 1993-09-16 | Smithkline Beecham Plc | Topical compositions containing steroids |
WO2003051903A1 (fr) * | 2001-12-19 | 2003-06-26 | Chugai Seiyaku Kabushiki Kaisha | Derive de l'androstane renfermant un substituant en position 7 et 17 |
Also Published As
Publication number | Publication date |
---|---|
NL184111B (nl) | 1988-11-16 |
FR2445340A1 (fr) | 1980-07-25 |
DK123476A (da) | 1976-09-22 |
CH631996A5 (en) | 1982-09-15 |
IL49132A (en) | 1980-05-30 |
IE42308B1 (en) | 1980-07-16 |
DK143757C (da) | 1982-03-22 |
IE42308L (en) | 1976-09-21 |
IL49132A0 (en) | 1976-05-31 |
IL58505A0 (en) | 1980-01-31 |
NL7602949A (nl) | 1976-09-23 |
FR2304345B1 (sv) | 1980-11-07 |
JPS51118756A (en) | 1976-10-18 |
DE2610497C2 (de) | 1986-10-16 |
CH621560A5 (en) | 1981-02-13 |
JPS61178920A (ja) | 1986-08-11 |
FR2445340B1 (sv) | 1983-02-11 |
AT357700B (de) | 1980-07-25 |
BE839751A (fr) | 1976-09-20 |
ATA191376A (de) | 1979-12-15 |
DK143757B (da) | 1981-10-05 |
SE7902256L (sv) | 1979-03-13 |
FR2304345A1 (fr) | 1976-10-15 |
AU1220776A (en) | 1977-09-22 |
NL184111C (nl) | 1989-04-17 |
DE2610497A1 (de) | 1976-10-07 |
JPS625920B2 (sv) | 1987-02-07 |
AU501246B2 (en) | 1979-06-14 |
SE7603410L (sv) | 1976-09-22 |
JPS6355488B2 (sv) | 1988-11-02 |
CA1069498A (en) | 1980-01-08 |
ZA761324B (en) | 1977-02-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
PE20 | Patent expired after termination of 20 years |
Effective date: 19960226 |