GB1517164A - Substituted-phenyl ketones and a process for the manufacture thereof - Google Patents
Substituted-phenyl ketones and a process for the manufacture thereofInfo
- Publication number
- GB1517164A GB1517164A GB36567/74A GB3656774A GB1517164A GB 1517164 A GB1517164 A GB 1517164A GB 36567/74 A GB36567/74 A GB 36567/74A GB 3656774 A GB3656774 A GB 3656774A GB 1517164 A GB1517164 A GB 1517164A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- naturally occurring
- amino acid
- acyl group
- acid addition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06043—Leu-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
- C07K5/06095—Arg-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Furan Compounds (AREA)
Priority Applications (37)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB36567/74A GB1517164A (en) | 1974-08-20 | 1974-08-20 | Substituted-phenyl ketones and a process for the manufacture thereof |
| GB28087/77A GB1517165A (en) | 1974-08-20 | 1975-05-21 | Substituted-phenyl ketones containing a protected dipeptide residue |
| CH1053375A CH620900A5 (en) | 1974-08-20 | 1975-08-13 | Process for the preparation of substituted phenylketones |
| ZA00755197A ZA755197B (en) | 1974-08-20 | 1975-08-13 | Phenyl ketones |
| IL47936A IL47936A (en) | 1974-08-20 | 1975-08-18 | Dipeptide- triazoly- and imidazolyl derivatives of benzophenone and pyridyl phenyl ketone their preparation and pharmaceutical compositions containing them |
| PH17475A PH16616A (en) | 1974-08-20 | 1975-08-18 | Substituted phenyl ketones |
| US05/605,580 US4007219A (en) | 1974-08-20 | 1975-08-18 | Benzophenone glycinamide derivatives |
| JP50099885A JPS6018656B2 (ja) | 1974-08-20 | 1975-08-19 | 置換されたフエニルケトンの製造方法 |
| DK373975A DK149284C (da) | 1974-08-20 | 1975-08-19 | Analogifremgangsmaade til fremstilling af l-lysylglycin-n-(2-benzoyl-4-chlorphenyl)-n-methylamid eller syreadditionssalte deraf samt forbindelser til anvendelse som udgangsforbindelser ved fremgangsmaaden |
| LU73219A LU73219A1 (https=) | 1974-08-20 | 1975-08-19 | |
| IE2210/78A IE42156B1 (en) | 1974-08-20 | 1975-08-19 | Substituted-phenyl ketones containing a protected dipetideresidue |
| DD187930A DD123086A5 (https=) | 1974-08-20 | 1975-08-19 | |
| BE159285A BE832532A (fr) | 1974-08-20 | 1975-08-19 | Cetons phenyliques |
| AT642175A AT348985B (de) | 1974-08-20 | 1975-08-19 | Verfahren zur herstellung neuer substituierter phenylketone |
| IE2209/78A IE42155B1 (en) | 1974-08-20 | 1975-08-19 | A substituted-phenyl ketone containing a dipeptide residueand a process for the manufacture thereof |
| FR7525632A FR2282261A1 (fr) | 1974-08-20 | 1975-08-19 | Cetones phenyliques |
| IE1826/75A IE42154B1 (en) | 1974-08-20 | 1975-08-19 | Substituted-phenyl ketones and a process for the manufacture thereof |
| AU84074/75A AU502104B2 (en) | 1974-08-20 | 1975-08-19 | Heterocyclic peptides |
| AR260048A AR217041A1 (es) | 1974-08-20 | 1975-08-19 | Procedimiento para la preparacion de derivados de aminoacidos n-(4-halo-o nitro-2-benzoil-o-monohalobenzoil o picolinoil)glicinamidas y los correspondientes 2-(3-aminometil-4h-1,2,4-triazol-4-il)y 2-(5-aminometil-1-imidazolil) |
| CA000233720A CA1177069A (en) | 1974-08-20 | 1975-08-19 | Phenyl ketones |
| SE7509268A SE426319B (sv) | 1974-08-20 | 1975-08-19 | Forfarande for framstellning av substituerade fenylketoner med sedativ, muskelrelaxerande och antikonvulsiv verkan |
| ES440315A ES440315A1 (es) | 1974-08-20 | 1975-08-19 | Un procedimiento para la preparacion de cetonas fenil susti-tuidas. |
| NO752876A NO150199C (no) | 1974-08-20 | 1975-08-19 | Analogifremgangsmaate for fremstilling av terapeutisk aktive fenylketoner |
| DE19752537069 DE2537069A1 (de) | 1974-08-20 | 1975-08-20 | Phenylketone |
| NL7509884A NL7509884A (nl) | 1974-08-20 | 1975-08-20 | Werkwijze voor het bereiden van fenylketonen. |
| FI752350A FI66592C (fi) | 1974-08-20 | 1975-08-20 | Foerfarande foer framstaellning av terapeutiskt anvaendbara sustituerade fenylketoner |
| FR7622695A FR2315914A1 (fr) | 1974-08-20 | 1976-07-26 | Nouvelles cetones phenyliques, leur application en tant que medicaments et un procede pour leur preparation |
| US05/740,917 US4071525A (en) | 1974-08-20 | 1976-11-11 | Substituted phenyl ketones |
| US05/740,894 US4044017A (en) | 1974-08-20 | 1976-11-11 | Substituted phenyl ketones |
| US05/740,701 US4069229A (en) | 1974-08-20 | 1976-11-11 | Substituted phenyl ketones |
| US05/741,084 US4046751A (en) | 1974-08-20 | 1976-11-11 | Substituted phenyl ketones |
| US05/741,001 US4105852A (en) | 1974-08-20 | 1976-11-11 | Substituted phenyl ketones |
| AT706177A AT345282B (de) | 1974-08-20 | 1977-10-04 | Verfahren zur herstellung neuer diazol bzw. triazol- substituierter phenylketone |
| US05/929,383 USRE30473E (en) | 1974-07-20 | 1978-07-31 | Benzophenone glycinamide derivatives |
| SE7902522A SE438153B (sv) | 1974-08-20 | 1979-03-20 | Forfarande for framstellning av l-lysyl-n-(2-bensoyl-4-klorfenyl)-n-metylglycinamid med sedativ, muskelrelaxerande och antikonvulsiv verkan |
| SE7902521A SE438152B (sv) | 1974-08-20 | 1979-03-20 | Forfarande for framstellning av substituerade fenylketoner med sedativ, muskelrelaxerande och antikonvulsiv verkan |
| JP58024922A JPS58150549A (ja) | 1974-08-20 | 1983-02-18 | 置換されたフエニルケトンの製造方法 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB36567/74A GB1517164A (en) | 1974-08-20 | 1974-08-20 | Substituted-phenyl ketones and a process for the manufacture thereof |
| GB2182175 | 1975-05-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1517164A true GB1517164A (en) | 1978-07-12 |
Family
ID=26255542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB36567/74A Expired GB1517164A (en) | 1974-07-20 | 1974-08-20 | Substituted-phenyl ketones and a process for the manufacture thereof |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS6018656B2 (https=) |
| AR (1) | AR217041A1 (https=) |
| AT (1) | AT348985B (https=) |
| AU (1) | AU502104B2 (https=) |
| CA (1) | CA1177069A (https=) |
| CH (1) | CH620900A5 (https=) |
| DD (1) | DD123086A5 (https=) |
| DE (1) | DE2537069A1 (https=) |
| DK (1) | DK149284C (https=) |
| ES (1) | ES440315A1 (https=) |
| FI (1) | FI66592C (https=) |
| FR (1) | FR2282261A1 (https=) |
| GB (1) | GB1517164A (https=) |
| IL (1) | IL47936A (https=) |
| LU (1) | LU73219A1 (https=) |
| NL (1) | NL7509884A (https=) |
| NO (1) | NO150199C (https=) |
| PH (1) | PH16616A (https=) |
| SE (1) | SE426319B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5484586A (en) * | 1977-12-05 | 1979-07-05 | Kali Chemie Pharma Gmbh | 1*44benzodiazepin derivatives*their manufacture and medical drug active to center control*antispasm*muscle relaxation*anxiety mollification and tranquilization |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN184976B (https=) * | 1996-06-13 | 2000-10-14 | Ranbaxy Lab Ltd |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3709898A (en) * | 1971-02-09 | 1973-01-09 | Upjohn Co | Process for the production of triazolobenzodiazepines and intermediates |
| JPS526861B2 (https=) * | 1972-05-27 | 1977-02-25 | ||
| ZA735932B (en) * | 1972-09-21 | 1974-07-31 | Hoffmann La Roche | Benzodiazepine derivatives |
-
1974
- 1974-08-20 GB GB36567/74A patent/GB1517164A/en not_active Expired
-
1975
- 1975-08-13 CH CH1053375A patent/CH620900A5/de not_active IP Right Cessation
- 1975-08-18 IL IL47936A patent/IL47936A/xx unknown
- 1975-08-18 PH PH17475A patent/PH16616A/en unknown
- 1975-08-19 LU LU73219A patent/LU73219A1/xx unknown
- 1975-08-19 DK DK373975A patent/DK149284C/da active
- 1975-08-19 AT AT642175A patent/AT348985B/de not_active IP Right Cessation
- 1975-08-19 JP JP50099885A patent/JPS6018656B2/ja not_active Expired
- 1975-08-19 SE SE7509268A patent/SE426319B/xx not_active IP Right Cessation
- 1975-08-19 ES ES440315A patent/ES440315A1/es not_active Expired
- 1975-08-19 DD DD187930A patent/DD123086A5/xx unknown
- 1975-08-19 AU AU84074/75A patent/AU502104B2/en not_active Expired
- 1975-08-19 NO NO752876A patent/NO150199C/no unknown
- 1975-08-19 FR FR7525632A patent/FR2282261A1/fr active Granted
- 1975-08-19 CA CA000233720A patent/CA1177069A/en not_active Expired
- 1975-08-19 AR AR260048A patent/AR217041A1/es active
- 1975-08-20 FI FI752350A patent/FI66592C/fi not_active IP Right Cessation
- 1975-08-20 DE DE19752537069 patent/DE2537069A1/de active Granted
- 1975-08-20 NL NL7509884A patent/NL7509884A/xx not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5484586A (en) * | 1977-12-05 | 1979-07-05 | Kali Chemie Pharma Gmbh | 1*44benzodiazepin derivatives*their manufacture and medical drug active to center control*antispasm*muscle relaxation*anxiety mollification and tranquilization |
| EP0024272A1 (de) * | 1977-12-05 | 1981-03-04 | Kali-Chemie Pharma GmbH | 1,4-Benzodiazepinderivate und ihre Salze; Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneipräparate |
Also Published As
| Publication number | Publication date |
|---|---|
| NO150199B (no) | 1984-05-28 |
| IL47936A0 (en) | 1975-11-25 |
| FI66592B (fi) | 1984-07-31 |
| CH620900A5 (en) | 1980-12-31 |
| FI752350A7 (https=) | 1976-02-21 |
| AU502104B2 (en) | 1979-07-12 |
| JPS6018656B2 (ja) | 1985-05-11 |
| NO752876L (https=) | 1976-02-23 |
| LU73219A1 (https=) | 1977-04-15 |
| DD123086A5 (https=) | 1976-11-20 |
| DE2537069C2 (https=) | 1988-09-08 |
| DK149284C (da) | 1986-10-13 |
| FI66592C (fi) | 1984-11-12 |
| JPS51125048A (en) | 1976-11-01 |
| DE2537069A1 (de) | 1976-03-04 |
| ATA642175A (de) | 1978-08-15 |
| NO150199C (no) | 1984-09-05 |
| AR217041A1 (es) | 1980-02-29 |
| DK149284B (da) | 1986-04-21 |
| DK373975A (da) | 1976-02-21 |
| SE426319B (sv) | 1982-12-27 |
| AU8407475A (en) | 1977-02-24 |
| FR2282261B1 (https=) | 1978-11-10 |
| NL7509884A (nl) | 1976-02-24 |
| IL47936A (en) | 1980-01-31 |
| PH16616A (en) | 1983-11-28 |
| SE7509268L (sv) | 1976-02-23 |
| CA1177069A (en) | 1984-10-30 |
| AT348985B (de) | 1979-03-12 |
| FR2282261A1 (fr) | 1976-03-19 |
| ES440315A1 (es) | 1977-09-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE127801T1 (de) | Pyrazolopyridinverbindungen und verfahren zu ihrer herstellung. | |
| ATE20469T1 (de) | Carboxyalkyl-dipeptide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. | |
| DK0659174T3 (da) | Derivater af valproinsyre og 2-valproensyreamider samt deres anvendelse som antikonvulsive midler | |
| MY101359A (en) | 7-acylamino-3-vinylcephalosporanic acid derivatives, processes for their preparation, pharmaceutical compositions containing them, their starting compounds and their preparation | |
| DK623586A (da) | Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne | |
| SE9203825L (sv) | Dubbelt verkande inhibitorer foer no-syntas och cyklooxygenas, foerfarande foer framstaellning daerav och terapeutiska kompositioner innehaallande desamma | |
| ES8306160A1 (es) | "procedimiento para preparar un nuevo compuesto de cefem". | |
| IE812974L (en) | Tri-,tetra- and penta peptides | |
| HUP9900040A2 (hu) | NMDA antagonista hatású tetrahidrokinolinszármazékok, eljárás előállításukra és a vegyületeket tartalmazó gyógyászati készítmények | |
| DK536581A (da) | Fremgangsmaade til fremstilling af carbonsyreamider | |
| IE812888L (en) | Phenylalkylamines. | |
| ATE19773T1 (de) | Nitroaliphatische verbindungen, verfahren zu deren herstellung und deren verwendung. | |
| ATE181728T1 (de) | Substituierte kynurenine, ein verfahren zu ihrer darstellung und ihrer verwendung als medikamente | |
| GB1517164A (en) | Substituted-phenyl ketones and a process for the manufacture thereof | |
| BG88028A (bg) | Амиди на циклометилен-1,2-дикарбоксилни киселини с терапевтична активност,методи за получаването им и фармацевтични състави, които ги съдържат | |
| ES8205224A1 (es) | Un procedimiento para la preparacion de acidos 1-carbadetiapen-2-em-3-carboxilios 6-1-y 2-sustituidos. | |
| ES8700241A1 (es) | Procedimiento para la preparacion de derivados de acidos 1- fenil-imidazol-5-carboxilicos | |
| KR910007912A (ko) | 피리돈의 신규 유도체, 이들의 제조 방법, 신규 중간체, 약제로서 이들의 용도 및 이들을 함유한 조성물 | |
| HUT49613A (en) | Process for producing new 8-aza-1,4-dioxaspiro/4,5/decan-2-ylmethyl ester derivatives of 1,4-dihydropyridine-3,5-dicarboxylic acids and pharmaceutical compositions comprising same | |
| ATE15375T1 (de) | Anthracyclin-glycoside, zwischenprodukte, verfahren zu beider herstellung und arzneimittel. | |
| GB1517165A (en) | Substituted-phenyl ketones containing a protected dipeptide residue | |
| RU99125652A (ru) | Косметический состав и способ для замедления процессов старения кожи | |
| GB1517166A (en) | Substituted-phenyl ketone containing a dipeptide residue and a process for the manufacture thereof | |
| ATE117689T1 (de) | Verfahren zur herstellung von lactamderivaten. | |
| JPS5395919A (en) | New derivatives of amino acid |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |