JPS5484586A - 1*44benzodiazepin derivatives*their manufacture and medical drug active to center control*antispasm*muscle relaxation*anxiety mollification and tranquilization - Google Patents

1*44benzodiazepin derivatives*their manufacture and medical drug active to center control*antispasm*muscle relaxation*anxiety mollification and tranquilization

Info

Publication number
JPS5484586A
JPS5484586A JP14731678A JP14731678A JPS5484586A JP S5484586 A JPS5484586 A JP S5484586A JP 14731678 A JP14731678 A JP 14731678A JP 14731678 A JP14731678 A JP 14731678A JP S5484586 A JPS5484586 A JP S5484586A
Authority
JP
Japan
Prior art keywords
mollification
antispasm
tranquilization
anxiety
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14731678A
Other languages
Japanese (ja)
Other versions
JPS6310698B2 (en
Inventor
Riipuman Hansu
Hiyushiensu Rorufu
Mirukofusukii Buorufugangu
Tsuoiguneru Horusuto
Butsuden Renke
Baaruzen Jiyakuriin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Products GmbH
Original Assignee
Kali Chemie Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma GmbH filed Critical Kali Chemie Pharma GmbH
Publication of JPS5484586A publication Critical patent/JPS5484586A/en
Publication of JPS6310698B2 publication Critical patent/JPS6310698B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
JP14731678A 1977-12-05 1978-11-30 1*44benzodiazepin derivatives*their manufacture and medical drug active to center control*antispasm*muscle relaxation*anxiety mollification and tranquilization Granted JPS5484586A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772754112 DE2754112A1 (en) 1977-12-05 1977-12-05 1,4-BENZODIAZEPINE DERIVATIVES, THEIR SALTS AND MEDICINAL PREPARATIONS CONTAINING THESE COMPOUNDS

Publications (2)

Publication Number Publication Date
JPS5484586A true JPS5484586A (en) 1979-07-05
JPS6310698B2 JPS6310698B2 (en) 1988-03-08

Family

ID=6025339

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14731678A Granted JPS5484586A (en) 1977-12-05 1978-11-30 1*44benzodiazepin derivatives*their manufacture and medical drug active to center control*antispasm*muscle relaxation*anxiety mollification and tranquilization

Country Status (6)

Country Link
US (1) US4170649A (en)
EP (1) EP0024272B1 (en)
JP (1) JPS5484586A (en)
DE (2) DE2754112A1 (en)
ES (1) ES475131A1 (en)
HU (1) HU179210B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4390471A (en) * 1978-05-15 1983-06-28 Hoffmann-La Roche Inc. Imidazodiazepines and processes therefor
US4368159A (en) * 1978-05-15 1983-01-11 Hoffmann-La Roche Inc. Intermediates to produce imidazodiazepines
US4368157A (en) * 1978-05-15 1983-01-11 Hoffmann-La Roche Inc. Intermediates to produce imidazodiazepines
US4368158A (en) * 1978-05-15 1983-01-11 Hoffmann-La Roche Inc. Intermediates to produce imidazodiazepines
US4371468A (en) * 1978-05-15 1983-02-01 Hoffmann-La Roche Inc. Intermediates to produce imidazodiazepines
US4256637A (en) * 1979-12-20 1981-03-17 Hoffmann-La Roche Inc. Intermediates for the production of imidazobenzodiazepines
US4335042A (en) * 1980-04-21 1982-06-15 Hoffmann-La Roche Inc. Process to produce imidazobenzodiazepine intermediates
US4752448A (en) * 1985-12-18 1988-06-21 Keystone Diagnostics, Inc. Drug abuse test paper

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4941389A (en) * 1972-05-03 1974-04-18
DE2353187A1 (en) * 1973-05-02 1974-11-14 Kali Chemie Ag 2-(Subst. aminomethyl)-1,4-benzodiazepines - useful as tranquillisers with only slight musculotropic effect
GB1517164A (en) * 1974-08-20 1978-07-12 Roche Products Ltd Substituted-phenyl ketones and a process for the manufacture thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2221536A1 (en) * 1972-05-03 1973-11-22 Kali Chemie Ag Benzodiazepin-2-ones prepn - by oxidn of 5-phenyl -2,3-dihydro-2-(substd methyl)-1,4-benzodiazepines
DE2358187A1 (en) * 1973-11-22 1975-05-28 Ernst Schweppe Heater for oil-atomizing or combustion air of water-heater burner - is pot shaped heated from boiler, with air channels from fan
US3998209A (en) * 1975-12-16 1976-12-21 Macvaugh Gilbert S Snoring deconditioning system and method
US4125726A (en) * 1977-03-11 1978-11-14 Hoffmann-La Roche Inc. Imidazo[1,5-a][1,4]benzodiazepines

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4941389A (en) * 1972-05-03 1974-04-18
DE2353187A1 (en) * 1973-05-02 1974-11-14 Kali Chemie Ag 2-(Subst. aminomethyl)-1,4-benzodiazepines - useful as tranquillisers with only slight musculotropic effect
GB1517164A (en) * 1974-08-20 1978-07-12 Roche Products Ltd Substituted-phenyl ketones and a process for the manufacture thereof

Also Published As

Publication number Publication date
HU179210B (en) 1982-09-28
DE2754112A1 (en) 1979-06-13
DE2862122D1 (en) 1983-01-13
JPS6310698B2 (en) 1988-03-08
US4170649A (en) 1979-10-09
EP0024272A1 (en) 1981-03-04
ES475131A1 (en) 1979-04-01
EP0024272B1 (en) 1982-12-08

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