GB1459392A - Heterocyclic compounds - Google Patents
Heterocyclic compoundsInfo
- Publication number
- GB1459392A GB1459392A GB5952472A GB5952472A GB1459392A GB 1459392 A GB1459392 A GB 1459392A GB 5952472 A GB5952472 A GB 5952472A GB 5952472 A GB5952472 A GB 5952472A GB 1459392 A GB1459392 A GB 1459392A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- alkyl
- phenyl
- cycloalkyl
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 15
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 10
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 10
- 150000001875 compounds Chemical class 0.000 abstract 8
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 7
- 125000001424 substituent group Chemical group 0.000 abstract 6
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 3
- 150000001408 amides Chemical class 0.000 abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 229910052799 carbon Inorganic materials 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 3
- 229910052731 fluorine Inorganic materials 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 238000006263 metalation reaction Methods 0.000 abstract 3
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- WBDQZHONDVMBJO-UHFFFAOYSA-N 2-(1,2,4-oxadiazol-3-yl)acetic acid Chemical class OC(=O)CC=1N=CON=1 WBDQZHONDVMBJO-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000005073 adamantyl group Chemical group C12(CC3CC(CC(C1)C3)C2)* 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- YGBFLZPYDUKSPT-MRVPVSSYSA-N cephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)C[C@H]21 YGBFLZPYDUKSPT-MRVPVSSYSA-N 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 230000003001 depressive effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 201000011243 gastrointestinal stromal tumor Diseases 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- WCPAKWJPBJAGKN-UHFFFAOYSA-N oxadiazole Chemical group C1=CON=N1 WCPAKWJPBJAGKN-UHFFFAOYSA-N 0.000 abstract 1
- 125000001715 oxadiazolyl group Chemical group 0.000 abstract 1
- RBKMMJSQKNKNEV-RITPCOANSA-N penicillanic acid Chemical compound OC(=O)[C@H]1C(C)(C)S[C@@H]2CC(=O)N21 RBKMMJSQKNKNEV-RITPCOANSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- -1 substituted-carbamoyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Priority Applications (30)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5952472A GB1459392A (en) | 1972-12-22 | 1972-12-22 | Heterocyclic compounds |
FR7345508A FR2211232B1 (enrdf_load_stackoverflow) | 1972-12-22 | 1973-12-19 | |
NL7317432.A NL162654C (nl) | 1972-12-22 | 1973-12-20 | Werkwijze voor het bereiden van 7-acylaminocefalosporan- zuurderivaten en antibacteriele en desinfecterende preparaten die deze cefalosporinen bevatten. |
JP48143379A JPS4994695A (enrdf_load_stackoverflow) | 1972-12-22 | 1973-12-21 | |
HUGI197A HU167924B (enrdf_load_stackoverflow) | 1972-12-22 | 1973-12-21 | |
AT1072573A AT344318B (de) | 1972-12-22 | 1973-12-21 | Verfahren zur herstellung von neuen 6-subst.- aminopenicillansaeure- und 7-subst.- aminocephalosporansaeure- derivaten |
DE2365705A DE2365705A1 (de) | 1972-12-22 | 1973-12-21 | Pharmazeutisch wertvolle neue 1,2,4-oxadiazolyl-essigsaeure-derivate und verfahren zu ihrer herstellung und ihre verwendung |
ES421726A ES421726A1 (es) | 1972-12-22 | 1973-12-21 | Procedimiento para preparar derivados de acidos 6-sustitui-do-amino-penicilanicos y 7-sustituido-aminocefalosporanicos. |
DE2364129A DE2364129A1 (de) | 1972-12-22 | 1973-12-21 | Pharmazeutisch wertvolle neue 1,2,4oxadiazolyl-essigsaeure-derivate und verfahren zu ihrer herstellung und ihre verwendung |
BE139223A BE809037A (fr) | 1972-12-22 | 1973-12-21 | Composes heterocycliques |
ES423962A ES423962A1 (es) | 1972-12-22 | 1974-03-06 | Procedimiento para preparar derivados de acidos 6-sustitui-do-aminopenicilanicos y 7-sustituido-aminocefalosporanicos. |
ES423963A ES423963A1 (es) | 1972-12-22 | 1974-03-06 | Procedimiento para preparar derivados de acidos 6-sustitui-do-aminopenicilanicos y cegalosporanicos. |
DK279875A DK279875A (enrdf_load_stackoverflow) | 1972-12-22 | 1975-06-20 | |
DK279975A DK279975A (enrdf_load_stackoverflow) | 1972-12-22 | 1975-06-20 | |
DK280075A DK280075A (enrdf_load_stackoverflow) | 1972-12-22 | 1975-06-20 | |
FR7600026A FR2289171A1 (fr) | 1972-12-22 | 1976-01-02 | Composes heterocycliques |
AT406676A AT350050B (de) | 1972-12-22 | 1976-06-03 | Verfahren zur herstellung von neuen, substi- tuierten 1,2,4-oxadiazol-yl-essigsaeuren, deren salzen und estern |
NO762441A NO762441L (enrdf_load_stackoverflow) | 1972-12-22 | 1976-07-12 | |
NO762440A NO762440L (enrdf_load_stackoverflow) | 1972-12-22 | 1976-07-12 | |
AT704976A AT344325B (de) | 1972-12-22 | 1976-09-23 | Verfahren zur herstellung von neuen 6-subst.- aminopenicillansaeure- und 7-subst.-aminocephalosporansaeure-derivaten |
AT704876A AT344324B (de) | 1972-12-22 | 1976-09-23 | Verfahren zur herstellung von neuen 6-subst.-aminopenicillansaeure- und 7-subst.-aminocephalosporansaeure-derivaten |
SE7611134A SE7611134L (sv) | 1972-12-22 | 1976-10-07 | Heterocylkiska foreningar |
SE7611135A SE7611135L (sv) | 1972-12-22 | 1976-10-07 | Heterocykliska foreningar |
US05/795,024 US4160829A (en) | 1972-12-22 | 1977-05-09 | Antibacterial 1,2,4-oxadiazolylacetamido cephalosporins |
JP14377377A JPS5377088A (en) | 1972-12-22 | 1977-11-30 | Process for preparing heterocyclic compound |
JP14377477A JPS5373565A (en) | 1972-12-22 | 1977-11-30 | Method of producing substituted 1*2*44 oxadiazolyllacetic acid and its salt |
NL7807076A NL7807076A (nl) | 1972-12-22 | 1978-06-30 | Gesubstitueerde 1,2,4-oxadiazolylazijnzuren en zouten en esters ervan, werkwijze ter bereiding hiervan, als- mede deze derivaten bevattende farmaceutische prepara- ten en de bereiding ervan. |
AT502478A ATA502478A (de) | 1972-12-22 | 1978-07-12 | Verfahren zur herstellung von neuen, substituierten 1,2,4-oxadiazol-yl-essigsaeuren, sowie deren salzen und estern |
FI782488A FI782488A7 (fi) | 1972-12-22 | 1978-08-15 | Nya 1,2,4-oxadiazolylaettiksyra-derivat och foerfarande foer framstaellning av desamma |
SE7905814A SE7905814L (sv) | 1972-12-22 | 1979-07-03 | Heterocykliska foreningar |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5952472A GB1459392A (en) | 1972-12-22 | 1972-12-22 | Heterocyclic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1459392A true GB1459392A (en) | 1976-12-22 |
Family
ID=10483917
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5952472A Expired GB1459392A (en) | 1972-12-22 | 1972-12-22 | Heterocyclic compounds |
Country Status (10)
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3905893A (en) * | 1973-08-22 | 1975-09-16 | Gulf Research Development Co | Plural stage residue hydrodesulfurization process |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1364453A (en) * | 1970-11-06 | 1974-08-21 | Gist Brocades Nv | Penicillanic and cepholosporanic acid derivatives |
-
1972
- 1972-12-22 GB GB5952472A patent/GB1459392A/en not_active Expired
-
1973
- 1973-12-19 FR FR7345508A patent/FR2211232B1/fr not_active Expired
- 1973-12-20 NL NL7317432.A patent/NL162654C/xx active
- 1973-12-21 DE DE2365705A patent/DE2365705A1/de active Pending
- 1973-12-21 HU HUGI197A patent/HU167924B/hu unknown
- 1973-12-21 BE BE139223A patent/BE809037A/xx unknown
- 1973-12-21 ES ES421726A patent/ES421726A1/es not_active Expired
- 1973-12-21 DE DE2364129A patent/DE2364129A1/de not_active Withdrawn
- 1973-12-21 AT AT1072573A patent/AT344318B/de not_active IP Right Cessation
- 1973-12-21 JP JP48143379A patent/JPS4994695A/ja active Pending
-
1974
- 1974-03-06 ES ES423962A patent/ES423962A1/es not_active Expired
- 1974-03-06 ES ES423963A patent/ES423963A1/es not_active Expired
-
1976
- 1976-01-02 FR FR7600026A patent/FR2289171A1/fr not_active Withdrawn
- 1976-10-07 SE SE7611135A patent/SE7611135L/xx unknown
- 1976-10-07 SE SE7611134A patent/SE7611134L/xx unknown
-
1977
- 1977-11-30 JP JP14377377A patent/JPS5377088A/ja active Pending
- 1977-11-30 JP JP14377477A patent/JPS5373565A/ja active Pending
-
1978
- 1978-06-30 NL NL7807076A patent/NL7807076A/xx not_active Application Discontinuation
-
1979
- 1979-07-03 SE SE7905814A patent/SE7905814L/xx unknown
Also Published As
Publication number | Publication date |
---|---|
SE7905814L (sv) | 1979-07-03 |
AT344318B (de) | 1978-07-10 |
ATA1072573A (de) | 1977-11-15 |
BE809037A (fr) | 1974-06-21 |
FR2289171A1 (fr) | 1976-05-28 |
JPS4994695A (enrdf_load_stackoverflow) | 1974-09-09 |
JPS5377088A (en) | 1978-07-08 |
DE2365705A1 (de) | 1976-01-15 |
ES423962A1 (es) | 1976-07-01 |
ES421726A1 (es) | 1976-04-16 |
NL7807076A (nl) | 1978-10-31 |
JPS5373565A (en) | 1978-06-30 |
ES423963A1 (es) | 1976-07-01 |
NL162654C (nl) | 1980-06-16 |
HU167924B (enrdf_load_stackoverflow) | 1976-01-28 |
SE7611134L (sv) | 1976-10-07 |
SE7611135L (sv) | 1976-10-07 |
NL7317432A (enrdf_load_stackoverflow) | 1974-06-25 |
FR2211232A1 (enrdf_load_stackoverflow) | 1974-07-19 |
NL162654B (nl) | 1980-01-15 |
DE2364129A1 (de) | 1974-07-25 |
FR2211232B1 (enrdf_load_stackoverflow) | 1978-01-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |