GB1458029A - Sulphamylbenzoic acids and preparation thereof - Google Patents

Sulphamylbenzoic acids and preparation thereof

Info

Publication number
GB1458029A
GB1458029A GB5720773A GB5720773A GB1458029A GB 1458029 A GB1458029 A GB 1458029A GB 5720773 A GB5720773 A GB 5720773A GB 5720773 A GB5720773 A GB 5720773A GB 1458029 A GB1458029 A GB 1458029A
Authority
GB
United Kingdom
Prior art keywords
formula
compound
alkyl
prepared
hexamethyleneimino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5720773A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PFIZER
Pfizer Inc
Original Assignee
PFIZER
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US00318213A external-priority patent/US3843662A/en
Application filed by PFIZER, Pfizer Inc filed Critical PFIZER
Publication of GB1458029A publication Critical patent/GB1458029A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB5720773A 1972-12-26 1973-12-10 Sulphamylbenzoic acids and preparation thereof Expired GB1458029A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00318213A US3843662A (en) 1971-12-09 1972-12-26 2-halo-5-(substituted piperidino sulfonyl)benzoic acids

Publications (1)

Publication Number Publication Date
GB1458029A true GB1458029A (en) 1976-12-08

Family

ID=23237158

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5720773A Expired GB1458029A (en) 1972-12-26 1973-12-10 Sulphamylbenzoic acids and preparation thereof

Country Status (11)

Country Link
JP (2) JPS4986522A (cg-RX-API-DMAC10.html)
AR (1) AR214849A1 (cg-RX-API-DMAC10.html)
AU (1) AU6366973A (cg-RX-API-DMAC10.html)
BE (1) BE808939R (cg-RX-API-DMAC10.html)
CA (1) CA1012974A (cg-RX-API-DMAC10.html)
DE (1) DE2363786A1 (cg-RX-API-DMAC10.html)
ES (2) ES421767A2 (cg-RX-API-DMAC10.html)
FR (1) FR2211261B2 (cg-RX-API-DMAC10.html)
GB (1) GB1458029A (cg-RX-API-DMAC10.html)
NL (1) NL7317455A (cg-RX-API-DMAC10.html)
ZA (1) ZA739662B (cg-RX-API-DMAC10.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068407A1 (en) * 1981-06-22 1983-01-05 Hodogaya Chemical Co., Ltd. Aminosulfonylbenzoic acid derivatives
US4999134A (en) * 1987-09-25 1991-03-12 Basf Aktiengesellschaft Zinc salts, lead salts and/or calcium salts of carboxylic acids and their use as corrosion inhibitors

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068408A1 (en) * 1980-11-10 1983-01-05 Mochida Pharmaceutical Co., Ltd. Antiviral compositions and a method for treating virus diseases
NL8220205A (nl) * 1981-06-22 1983-05-02 Mochida Pharm Co Ltd Farmaceutisch preparaat met anti-virusactiviteit.
DE19941540C2 (de) * 1999-09-01 2002-08-29 Aventis Pharma Gmbh Sulfonylcarboxamide zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Hyperlipidämie

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1122541B (de) * 1959-12-28 1962-01-25 Hoechst Ag Verfahren zur Herstellung von Sulfamyl-anthranilsaeuren
FR1472906A (fr) * 1961-05-08 1967-03-17 Parke Davis & Co Esters d'acides 4-halo-3-sulfamoylbenzoïques et leur procédé de production
FR1450358A (fr) * 1960-09-03 1966-06-24 Parke Davis & Co Production de 4-halogéno-3-sulfamylbenzamides nouvelles
FR1311859A (fr) * 1961-09-18 1962-12-14 Soc Ind Fab Antibiotiques Sifa Nouveaux dérivés des sulfamides, et procédé de préparation
US3565920A (en) * 1966-12-29 1971-02-23 Ciba Geigy Corp 5-sulfamyl-anthranilic acids
US3567746A (en) * 1968-07-10 1971-03-02 Pennwalt Corp N-aryl benzamides
US3700773A (en) * 1969-06-25 1972-10-24 Merck & Co Inc Substituted phenylsulfamyl salicyclic acids and derivatives thereof in the treatment of inflammation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068407A1 (en) * 1981-06-22 1983-01-05 Hodogaya Chemical Co., Ltd. Aminosulfonylbenzoic acid derivatives
US4999134A (en) * 1987-09-25 1991-03-12 Basf Aktiengesellschaft Zinc salts, lead salts and/or calcium salts of carboxylic acids and their use as corrosion inhibitors

Also Published As

Publication number Publication date
ZA739662B (en) 1975-01-29
JPS4986522A (cg-RX-API-DMAC10.html) 1974-08-19
JPS5924975B2 (ja) 1984-06-13
FR2211261A2 (cg-RX-API-DMAC10.html) 1974-07-19
NL7317455A (cg-RX-API-DMAC10.html) 1974-06-28
FR2211261B2 (cg-RX-API-DMAC10.html) 1977-04-15
JPS58170756A (ja) 1983-10-07
ES425208A1 (es) 1976-06-16
CA1012974A (en) 1977-06-28
AR214849A1 (es) 1979-08-15
DE2363786A1 (de) 1974-07-11
BE808939R (fr) 1974-06-21
ES421767A2 (es) 1977-07-01
AU6366973A (en) 1975-06-19

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee