GB1427945A - Aminopyrrole derivatives - Google Patents
Aminopyrrole derivativesInfo
- Publication number
- GB1427945A GB1427945A GB3979073A GB3979073A GB1427945A GB 1427945 A GB1427945 A GB 1427945A GB 3979073 A GB3979073 A GB 3979073A GB 3979073 A GB3979073 A GB 3979073A GB 1427945 A GB1427945 A GB 1427945A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkoxy
- alkyl
- hydrogen
- carbo
- carbamyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- QLSWIGRIBOSFMV-UHFFFAOYSA-N 1h-pyrrol-2-amine Chemical class NC1=CC=CN1 QLSWIGRIBOSFMV-UHFFFAOYSA-N 0.000 title 1
- -1 bromo, hydroxy Chemical group 0.000 abstract 12
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 125000001424 substituent group Chemical group 0.000 abstract 4
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000000649 benzylidene group Chemical group [H]C(=[*])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 2
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 125000001153 fluoro group Chemical group F* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- WAUGGYPDCQZJKK-UHFFFAOYSA-N 1h-pyrrol-3-amine Chemical class NC=1C=CNC=1 WAUGGYPDCQZJKK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000004849 alkoxymethyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000001118 alkylidene group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 230000000994 depressogenic effect Effects 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000000168 pyrrolyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
Priority Applications (43)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3979073A GB1427945A (en) | 1973-08-22 | 1973-08-22 | Aminopyrrole derivatives |
| ZA00744754A ZA744754B (en) | 1973-08-22 | 1974-07-27 | New aminopyrrole derivator |
| IL45368A IL45368A (en) | 1973-08-22 | 1974-07-29 | Aminopyrrole derivatives |
| YU2141/74A YU36926B (en) | 1973-08-22 | 1974-08-01 | Process for obtaining new aminopyrrol derivatives |
| NO742862A NO143845C (no) | 1973-08-22 | 1974-08-08 | Analogifremgangsmaate til fremstilling av terapeutisk virksomme 3-amino-pyrrolderivater |
| IE1672/74A IE40290B1 (en) | 1973-08-22 | 1974-08-08 | Wew aminopyrrole derivatives |
| AU72210/74A AU481957B2 (en) | 1973-08-22 | 1974-08-12 | New aminopyrrole derivatives |
| DE2462967A DE2462967C2 (de) | 1973-08-22 | 1974-08-16 | Derivate des 3-Amino-5-methyl-2-phenyl-pyrrols, deren Salze und diese enthaltende pharmazeutische Zubereitung |
| DE2462963A DE2462963C2 (de) | 1973-08-22 | 1974-08-16 | Derivate des 2-Phenyl-3-amino-pyrrols deren Salze und diese enthaltende pharmazeutische Zubereitung |
| DE2462966A DE2462966C2 (de) | 1973-08-22 | 1974-08-16 | Derivate des 3-Amino-4-acetyl-5-methylpyrrols und diese enthaltende pharmazeutische Zubereitungen |
| DE2439284A DE2439284C2 (de) | 1973-08-22 | 1974-08-16 | 2-Phenyl-3-amino-4-acetyl-5-methylpyrrol, dessen Salze und diese Verbindungen enthaltende pharmazeutische Zubereitung |
| DD180545A DD113756A5 (enrdf_load_html_response) | 1973-08-22 | 1974-08-16 | |
| RO7491735A RO70535A (ro) | 1973-08-22 | 1974-08-19 | Procedeu pentru prepararea unor derivati ai 3-aminopirolului |
| RO79830A RO72882B (ro) | 1973-08-22 | 1974-08-19 | Procedeu de preparare a pirolului substituit |
| RO7491734A RO70534A (ro) | 1973-08-22 | 1974-08-19 | Procedeu pentru prepararea unor derivati ai 3-aminopirolului |
| NL7411092A NL7411092A (nl) | 1973-08-22 | 1974-08-20 | Werkwijze voor de bereiding van aminopyrrool- derivaten. |
| IN1864/CAL/1974A IN140329B (enrdf_load_html_response) | 1973-08-22 | 1974-08-20 | |
| LU70764A LU70764A1 (enrdf_load_html_response) | 1973-08-22 | 1974-08-20 | |
| FI2462/74A FI61879C (fi) | 1973-08-22 | 1974-08-21 | Analogifoerfarande foer framstaellning av nya terapeutiskt effektiva aminopyrrolderivat |
| CA207,472A CA1050556A (en) | 1973-08-22 | 1974-08-21 | Aminopyrrole derivatives |
| JP9600974A JPS5328914B2 (enrdf_load_html_response) | 1973-08-22 | 1974-08-21 | |
| HULE754A HU169728B (enrdf_load_html_response) | 1973-08-22 | 1974-08-21 | |
| SU742055571A SU843738A3 (ru) | 1973-08-22 | 1974-08-21 | Способ получени производных аминопиррола или его солей |
| SE7410636A SE394429B (sv) | 1973-08-22 | 1974-08-21 | Forfarande for framstellning av aminopyrrolderivat med terapeutisk verkan |
| DK445974A DK156391C (da) | 1973-08-22 | 1974-08-21 | Analogifremgangsmaade til fremstilling af 3-aminopyrrolderivater |
| CH1142674A CH605741A5 (enrdf_load_html_response) | 1973-08-22 | 1974-08-21 | |
| PL1974189700A PL96806B1 (pl) | 1973-08-22 | 1974-08-22 | Sposob wytwarzania nowych pochodnych aminopirolu |
| PL1974173617A PL95235B1 (enrdf_load_html_response) | 1973-08-22 | 1974-08-22 | |
| CS745833A CS188201B2 (en) | 1973-08-22 | 1974-08-22 | Method of producing novel derivatives of amino pyrrole |
| BE147818A BE819088A (fr) | 1973-08-22 | 1974-08-22 | Nouveaux derives d'aminopyrrole et leur preparation |
| FR7428894A FR2241308B1 (enrdf_load_html_response) | 1973-08-22 | 1974-08-22 | |
| ES429446A ES429446A1 (es) | 1973-08-22 | 1974-08-22 | Procedimiento para preparar derivados de aminopirrol. |
| AT684774A AT336600B (de) | 1973-08-22 | 1974-08-22 | Verfahren zur herstellung neuer aminopyrrolderivate und deren salze |
| AR255253A AR210246A1 (es) | 1973-08-22 | 1974-08-27 | Procedimiento para preparar nuevos derivados 2-,4-y5-sustituidos de 3-aminopirrol |
| AR263503A AR210133A1 (es) | 1973-08-22 | 1976-06-03 | Procedimiento para preparar nuevos derivados de 3-amino-5-metil-pirrol |
| AR263502A AR210132A1 (es) | 1973-08-22 | 1976-06-03 | Procedimiento para preparar nuevos derivados de 3-amino-4-acetil-5-metil-pirrol |
| ES449426A ES449426A1 (es) | 1973-08-22 | 1976-07-01 | Procedimiento para preparar derivados de aminopirrol. |
| ES449425A ES449425A1 (es) | 1973-08-22 | 1976-07-01 | Procedimiento para preparar derivados de aminopirrol. |
| US05/750,759 US4140696A (en) | 1973-08-22 | 1976-12-15 | Aminopyrrole derivatives |
| US05/960,386 US4211709A (en) | 1973-08-22 | 1978-11-13 | Aminopyrrole derivatives |
| US05/960,387 US4212806A (en) | 1973-08-22 | 1978-11-13 | Aminopyrrole derivatives |
| US05/960,385 US4211708A (en) | 1973-08-22 | 1978-11-13 | Aminopyrrole derivatives |
| US05/960,384 US4198502A (en) | 1973-08-22 | 1978-11-13 | Aminopyrrole derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3979073A GB1427945A (en) | 1973-08-22 | 1973-08-22 | Aminopyrrole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1427945A true GB1427945A (en) | 1976-03-10 |
Family
ID=10411528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3979073A Expired GB1427945A (en) | 1973-08-22 | 1973-08-22 | Aminopyrrole derivatives |
Country Status (27)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1492663A (en) * | 1975-02-20 | 1977-11-23 | Lepetit Spa | 4-amino-3-pyrrole carboxamides |
| GB1548398A (en) * | 1975-06-05 | 1979-07-11 | Lilly Industries Ltd | Acylamino pyrroles furans and thiophenes |
| DE3212591A1 (de) * | 1982-04-03 | 1983-10-13 | Gödecke AG, 1000 Berlin | 2-pyrrolin-3-carbonitril-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel |
| JPH0216740U (enrdf_load_html_response) * | 1988-07-21 | 1990-02-02 | ||
| DE59009489D1 (de) * | 1989-03-28 | 1995-09-14 | Ciba Geigy Ag | Substituierte Aminopyrrole als Stabilisatoren chlorhaltige Polymerisate. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1148909A (en) * | 1965-04-19 | 1969-04-16 | Sumitomo Chemical Co | Process for production of novel phenylhydrazone and phenylhydrazine derivatives |
| GB1187903A (en) * | 1967-09-29 | 1970-04-15 | Sumitomo Chemical Co | Glucuronides of 3-Indolylaliphatic Acid Derivatives and Processes for Producing them |
-
1973
- 1973-08-22 GB GB3979073A patent/GB1427945A/en not_active Expired
-
1974
- 1974-07-27 ZA ZA00744754A patent/ZA744754B/xx unknown
- 1974-07-29 IL IL45368A patent/IL45368A/en unknown
- 1974-08-01 YU YU2141/74A patent/YU36926B/xx unknown
- 1974-08-08 NO NO742862A patent/NO143845C/no unknown
- 1974-08-08 IE IE1672/74A patent/IE40290B1/en unknown
- 1974-08-16 DE DE2462966A patent/DE2462966C2/de not_active Expired
- 1974-08-16 DE DE2462967A patent/DE2462967C2/de not_active Expired
- 1974-08-16 DE DE2439284A patent/DE2439284C2/de not_active Expired
- 1974-08-16 DE DE2462963A patent/DE2462963C2/de not_active Expired
- 1974-08-16 DD DD180545A patent/DD113756A5/xx unknown
- 1974-08-19 RO RO7491734A patent/RO70534A/ro unknown
- 1974-08-19 RO RO79830A patent/RO72882B/ro unknown
- 1974-08-19 RO RO7491735A patent/RO70535A/ro unknown
- 1974-08-20 NL NL7411092A patent/NL7411092A/xx unknown
- 1974-08-20 LU LU70764A patent/LU70764A1/xx unknown
- 1974-08-20 IN IN1864/CAL/1974A patent/IN140329B/en unknown
- 1974-08-21 FI FI2462/74A patent/FI61879C/fi active
- 1974-08-21 SE SE7410636A patent/SE394429B/xx not_active IP Right Cessation
- 1974-08-21 CA CA207,472A patent/CA1050556A/en not_active Expired
- 1974-08-21 CH CH1142674A patent/CH605741A5/xx not_active IP Right Cessation
- 1974-08-21 HU HULE754A patent/HU169728B/hu not_active IP Right Cessation
- 1974-08-21 SU SU742055571A patent/SU843738A3/ru active
- 1974-08-21 JP JP9600974A patent/JPS5328914B2/ja not_active Expired
- 1974-08-21 DK DK445974A patent/DK156391C/da active
- 1974-08-22 ES ES429446A patent/ES429446A1/es not_active Expired
- 1974-08-22 PL PL1974173617A patent/PL95235B1/pl unknown
- 1974-08-22 FR FR7428894A patent/FR2241308B1/fr not_active Expired
- 1974-08-22 PL PL1974189700A patent/PL96806B1/pl unknown
- 1974-08-22 AT AT684774A patent/AT336600B/de not_active IP Right Cessation
- 1974-08-22 BE BE147818A patent/BE819088A/xx not_active IP Right Cessation
- 1974-08-22 CS CS745833A patent/CS188201B2/cs unknown
- 1974-08-27 AR AR255253A patent/AR210246A1/es active
-
1976
- 1976-06-03 AR AR263502A patent/AR210132A1/es active
- 1976-06-03 AR AR263503A patent/AR210133A1/es active
- 1976-07-01 ES ES449425A patent/ES449425A1/es not_active Expired
- 1976-07-01 ES ES449426A patent/ES449426A1/es not_active Expired
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19920725 |