GB1418363A - Process for the production of 6-piper-azinyl-morphanthridines and related tricyclics - Google Patents
Process for the production of 6-piper-azinyl-morphanthridines and related tricyclicsInfo
- Publication number
- GB1418363A GB1418363A GB1566773A GB1566773A GB1418363A GB 1418363 A GB1418363 A GB 1418363A GB 1566773 A GB1566773 A GB 1566773A GB 1566773 A GB1566773 A GB 1566773A GB 1418363 A GB1418363 A GB 1418363A
- Authority
- GB
- United Kingdom
- Prior art keywords
- thiophene
- acid
- alkyl
- reaction
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH489872A CH569730A5 (de) | 1972-04-04 | 1972-04-04 | |
| CH490172A CH569731A5 (de) | 1972-04-04 | 1972-04-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1418363A true GB1418363A (en) | 1975-12-17 |
Family
ID=25696493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1566773A Expired GB1418363A (en) | 1972-04-04 | 1973-04-02 | Process for the production of 6-piper-azinyl-morphanthridines and related tricyclics |
Country Status (28)
| Country | Link |
|---|---|
| JP (2) | JPS4913189A (de) |
| AR (1) | AR195913A1 (de) |
| AT (1) | AT340428B (de) |
| BE (1) | BE797671A (de) |
| BG (1) | BG21221A3 (de) |
| CA (1) | CA1029372A (de) |
| CH (2) | CH569730A5 (de) |
| CS (1) | CS178125B2 (de) |
| CY (1) | CY990A (de) |
| DD (1) | DD105614A5 (de) |
| DK (1) | DK150850C (de) |
| ES (1) | ES413252A1 (de) |
| FI (1) | FI61029C (de) |
| FR (1) | FR2179071B1 (de) |
| GB (1) | GB1418363A (de) |
| HK (1) | HK11079A (de) |
| HU (1) | HU166524B (de) |
| IL (1) | IL41936A (de) |
| LU (1) | LU67351A1 (de) |
| MY (1) | MY7900116A (de) |
| NL (1) | NL175621C (de) |
| NO (1) | NO138210C (de) |
| PH (1) | PH11180A (de) |
| PL (1) | PL89178B1 (de) |
| RO (1) | RO72458A (de) |
| SE (1) | SE399890B (de) |
| SU (1) | SU457220A3 (de) |
| YU (1) | YU39906B (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7491715B2 (en) | 2003-12-22 | 2009-02-17 | Acadia Pharmaceuticals, Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7403657A (de) * | 1973-03-23 | 1974-09-25 | ||
| JPS51135089A (en) * | 1975-05-19 | 1976-11-22 | Hitachi Zosen Corp | Under-water operation assistant ship |
| IT1207417B (it) * | 1982-03-15 | 1989-05-17 | Menarini Sas | Azepina-6-one ad attivita'composti triciclici derivati dalla farmacologica, e procedimenti di 5,6-diidro-11h-dibenzo (b,e)fabbricazione relativi |
| GB8607684D0 (en) * | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
| NZ590616A (en) | 2008-06-20 | 2012-09-28 | Astrazeneca Ab | Dibenzothiazepine derivatives and use thereof |
-
1972
- 1972-04-04 CH CH489872A patent/CH569730A5/xx not_active IP Right Cessation
- 1972-04-04 CH CH490172A patent/CH569731A5/xx not_active IP Right Cessation
-
1973
- 1973-01-29 JP JP48011246A patent/JPS4913189A/ja active Pending
- 1973-03-26 DK DK165273A patent/DK150850C/da not_active IP Right Cessation
- 1973-03-27 NO NO1257/73A patent/NO138210C/no unknown
- 1973-03-27 FI FI943/73A patent/FI61029C/fi active
- 1973-03-28 SE SE7304365A patent/SE399890B/xx unknown
- 1973-03-29 SU SU1900401A patent/SU457220A3/ru active
- 1973-03-30 PH PH14474A patent/PH11180A/en unknown
- 1973-03-30 NL NLAANVRAGE7304441,A patent/NL175621C/xx active Search and Examination
- 1973-04-02 PL PL1973161672A patent/PL89178B1/pl unknown
- 1973-04-02 BE BE129561A patent/BE797671A/xx not_active IP Right Cessation
- 1973-04-02 GB GB1566773A patent/GB1418363A/en not_active Expired
- 1973-04-02 CS CS2346A patent/CS178125B2/cs unknown
- 1973-04-02 YU YU881/73A patent/YU39906B/xx unknown
- 1973-04-02 RO RO7374359A patent/RO72458A/ro unknown
- 1973-04-02 CY CY990A patent/CY990A/xx unknown
- 1973-04-02 BG BG23138A patent/BG21221A3/xx unknown
- 1973-04-02 ES ES413252A patent/ES413252A1/es not_active Expired
- 1973-04-02 CA CA167,668A patent/CA1029372A/en not_active Expired
- 1973-04-03 AR AR247360A patent/AR195913A1/es active
- 1973-04-03 JP JP48037479A patent/JPS5142118B2/ja not_active Expired
- 1973-04-03 HU HUWA277A patent/HU166524B/hu unknown
- 1973-04-03 DD DD169911A patent/DD105614A5/xx unknown
- 1973-04-03 LU LU67351A patent/LU67351A1/xx unknown
- 1973-04-03 IL IL41936A patent/IL41936A/en unknown
- 1973-04-03 AT AT291173A patent/AT340428B/de not_active IP Right Cessation
- 1973-04-04 FR FR7312056A patent/FR2179071B1/fr not_active Expired
-
1979
- 1979-03-08 HK HK110/79A patent/HK11079A/xx unknown
- 1979-12-30 MY MY116/79A patent/MY7900116A/xx unknown
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7491715B2 (en) | 2003-12-22 | 2009-02-17 | Acadia Pharmaceuticals, Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| US7517871B2 (en) | 2003-12-22 | 2009-04-14 | Acadia Pharmaceuticals, Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| US7550454B2 (en) | 2003-12-22 | 2009-06-23 | Acadia Pharmaceuticals, Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| US7622461B2 (en) | 2003-12-22 | 2009-11-24 | Acadia Pharmaceuticals Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19930401 |