GB1215396A - Production of monothio-oxamic acid compounds - Google Patents
Production of monothio-oxamic acid compoundsInfo
- Publication number
- GB1215396A GB1215396A GB1862368A GB1862368A GB1215396A GB 1215396 A GB1215396 A GB 1215396A GB 1862368 A GB1862368 A GB 1862368A GB 1862368 A GB1862368 A GB 1862368A GB 1215396 A GB1215396 A GB 1215396A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- monothio
- amine
- oxamic
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/194—Radicals derived from thio- or thiono carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1,215,396. Monothio-oxamic acid compounds. BADISCHE ANILIN- & SODA-FABRIK A.G. 19 April, 1968 [21 April, 1967], No. 18623/68. Heading C2C. Monothio-oxamic acid amides of general formula where R<SP>1</SP> and R<SP>2</SP>, which may be the same or different, may be aliphatic, cycloaliphatic, araliphatic or aromatic, or R<SP>1</SP> denotes such a radical and R<SP>2</SP> denotes H, or R<SP>1</SP> with R<SP>2</SP> and the adjacent nitrogen may be a heterocyclic ring, and R<SP>3</SP> may be the radical -NH 2 or -OR<SP>4</SP>, where R<SP>4</SP> may be H, aliphatic, cycloaliphatic, araliphatic or aromatic, are prepared by reacting a haloacetic acid compound of the general formula where R<SP>1</SP>, R<SP>2</SP> and R<SP>3</SP> have the same meaning as above, R<SP>5</SP> may be a halogen atom, R<SP>6</SP> and R<SP>7</SP> may be H or halogen, with elemental sulphur and an amine having the general formula where R<SP>1</SP> and R<SP>2</SP> have the above meanings, in the presence of an acid-binding agent which may be identical with the amine, the amounts of amine and acid-binder being selected so as to favour the production of the desired product monothio-oxamic acid amide as compared to the undesired monothio-oxamic acid amide. The free haloacetic acid may be replaced by a salt of a haloacetic acid with an alkali metal, alkaline earth metal, unsubstituted ammonium or substituted ammonium cation and the process may be carried out in an inert organic solvent, e.g. alcohols, ethers or aromatic hydrocarbons at a temperature of 20-200‹ C., and preferably 50-150‹ C. Acid-binding agents such as tertiary amines, inorganic bases such as alkaline earth metal oxides, hydroxides or amides, alcoholates or salts of polybasic acids may be added to bind the acid present in the reaction, e.g. haloacetic acid as starting material or hydrogen halide formed.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEP1270A DE1270552B (en) | 1967-04-21 | 1967-04-21 | Process for the preparation of monothione oxalic acid amides |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1215396A true GB1215396A (en) | 1970-12-09 |
Family
ID=6986241
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1862368A Expired GB1215396A (en) | 1967-04-21 | 1968-04-19 | Production of monothio-oxamic acid compounds |
Country Status (6)
Country | Link |
---|---|
BE (1) | BE713737A (en) |
CH (1) | CH495340A (en) |
DE (1) | DE1270552B (en) |
FR (1) | FR1557489A (en) |
GB (1) | GB1215396A (en) |
NL (1) | NL6805585A (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2460909C2 (en) * | 1974-12-21 | 1986-02-27 | Bayer Ag, 5090 Leverkusen | Process for the preparation of alpha-oxothiodimethylamides |
US5232947A (en) * | 1988-07-04 | 1993-08-03 | Meiji Seika Kaisha, Ltd. | Oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain |
EP0350260B1 (en) * | 1988-07-04 | 1993-10-20 | Meiji Seika Kaisha Ltd. | New oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain |
AU7948400A (en) * | 1999-10-19 | 2001-04-30 | Taisho Pharmaceutical Co., Ltd. | N-cycloalkyl thiooxamide derivatives |
-
1967
- 1967-04-21 DE DEP1270A patent/DE1270552B/en active Granted
-
1968
- 1968-03-27 FR FR1557489D patent/FR1557489A/fr not_active Expired
- 1968-04-16 BE BE713737D patent/BE713737A/xx unknown
- 1968-04-18 CH CH572768A patent/CH495340A/en not_active IP Right Cessation
- 1968-04-19 NL NL6805585A patent/NL6805585A/xx unknown
- 1968-04-19 GB GB1862368A patent/GB1215396A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
BE713737A (en) | 1968-10-16 |
NL6805585A (en) | 1968-10-22 |
DE1270552C2 (en) | 1969-01-16 |
DE1270552B (en) | 1968-06-20 |
FR1557489A (en) | 1969-02-14 |
CH495340A (en) | 1970-08-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB1138529A (en) | Novel imidazole derivatives and a process for the manufacture thereof | |
GB1288678A (en) | ||
GB1215396A (en) | Production of monothio-oxamic acid compounds | |
GB1253743A (en) | Novel pyridine derivatives | |
GB1009302A (en) | Organic peroxides and a process for preparing them | |
GB1371022A (en) | Diglycidylbenzimidazolones and a process for their manufacture | |
GB1398201A (en) | N-sulphenylated carbamidoximes a process for their preparation and their fungicidal and bactericidal use | |
GB1321424A (en) | N-phenyl-n-disubstituted aminoalkyl-2-amino indanes | |
GB1047061A (en) | Polymers and a process for the preparation thereof | |
GB1377275A (en) | N-o-cyanophenyl-n,n,- disubstituted formamidines and their salts | |
GB1328947A (en) | Phenylhydrazones a process for their preparation and their use as insecticides acaricides and fungicides | |
GB1460417A (en) | Thiourea derivatives and their use as fungicides | |
ES394346A1 (en) | Procedure for the preparation of new 2-alquiltio-4,6 -diamino - s - triacinas of activity herbicida. (Machine-translation by Google Translate, not legally binding) | |
GB1363758A (en) | Process for the production of 1,2,4-oxa-diazoles and novel 1,2,4- oxadiazoles | |
GB1369159A (en) | Production of o-sulphamidobenzoic acids | |
GB1383523A (en) | Diphenylamine derivatives and pesticidal compositions thereof | |
GB1381210A (en) | Azomethines of 4-amino-5-h-1,2,4-triazin-5-ones process for their production and their use as herbicides | |
GB1509457A (en) | Pyridine derivatives | |
GB1200970A (en) | Process for producing benzyl cyanides and their homologues | |
US2467893A (en) | Piperazine carboxamides and method of preparing same | |
GB1254928A (en) | beta-ALKOXYACRYLIC ACID AMIDES | |
GB1215358A (en) | Production of dithiocarbamates | |
GB1132988A (en) | Pyridinealcohol carbamate and thioncarbamate derivatives and their (py)-n-oxides and process for the manufacture of them | |
GB1530675A (en) | Guanidine derivatives | |
GB1408843A (en) | Production of disubstituted formamidines |