GB1379730A - Pharmaceutical compositions - Google Patents
Pharmaceutical compositionsInfo
- Publication number
- GB1379730A GB1379730A GB6006770A GB6006770A GB1379730A GB 1379730 A GB1379730 A GB 1379730A GB 6006770 A GB6006770 A GB 6006770A GB 6006770 A GB6006770 A GB 6006770A GB 1379730 A GB1379730 A GB 1379730A
- Authority
- GB
- United Kingdom
- Prior art keywords
- water
- fatty
- soluble
- esters
- employed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 4
- 229930195729 fatty acid Natural products 0.000 abstract 4
- 239000000194 fatty acid Substances 0.000 abstract 4
- 239000007788 liquid Substances 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 239000003921 oil Substances 0.000 abstract 4
- 235000019198 oils Nutrition 0.000 abstract 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- 239000000839 emulsion Substances 0.000 abstract 3
- 150000002148 esters Chemical class 0.000 abstract 3
- -1 fatty acid esters Chemical class 0.000 abstract 3
- 239000000243 solution Substances 0.000 abstract 3
- 150000003431 steroids Chemical class 0.000 abstract 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 230000003444 anaesthetic effect Effects 0.000 abstract 2
- LZCLXQDLBQLTDK-UHFFFAOYSA-N ethyl 2-hydroxypropanoate Chemical compound CCOC(=O)C(C)O LZCLXQDLBQLTDK-UHFFFAOYSA-N 0.000 abstract 2
- 150000004665 fatty acids Chemical class 0.000 abstract 2
- 150000002191 fatty alcohols Chemical class 0.000 abstract 2
- DCAYPVUWAIABOU-UHFFFAOYSA-N hexadecane Chemical compound CCCCCCCCCCCCCCCC DCAYPVUWAIABOU-UHFFFAOYSA-N 0.000 abstract 2
- 238000002347 injection Methods 0.000 abstract 2
- 239000007924 injection Substances 0.000 abstract 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 abstract 2
- JNYAEWCLZODPBN-KVTDHHQDSA-N (2r,3r,4r)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical compound OC[C@@H](O)[C@H]1OC[C@@H](O)[C@H]1O JNYAEWCLZODPBN-KVTDHHQDSA-N 0.000 abstract 1
- DUHUCHOQIDJXAT-OLVMNOGESA-N 3-hydroxy-(3-α,5-α)-Pregnane-11,20-dione Chemical compound C([C@@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](C(=O)C)[C@@]2(C)CC1=O DUHUCHOQIDJXAT-OLVMNOGESA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000008121 dextrose Substances 0.000 abstract 1
- SNRUBQQJIBEYMU-UHFFFAOYSA-N dodecane Chemical compound CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 229940116333 ethyl lactate Drugs 0.000 abstract 1
- 125000005456 glyceride group Chemical group 0.000 abstract 1
- 229940074076 glycerol formal Drugs 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 229940057995 liquid paraffin Drugs 0.000 abstract 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 abstract 1
- 229940094933 n-dodecane Drugs 0.000 abstract 1
- 229960003966 nicotinamide Drugs 0.000 abstract 1
- 235000005152 nicotinamide Nutrition 0.000 abstract 1
- 239000011570 nicotinamide Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229940051841 polyoxyethylene ether Drugs 0.000 abstract 1
- 229920000056 polyoxyethylene ether Polymers 0.000 abstract 1
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 229940032094 squalane Drugs 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
- 235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
- 239000008158 vegetable oil Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB6006770A GB1379730A (en) | 1970-12-17 | 1970-12-17 | Pharmaceutical compositions |
| IE1595/71A IE36705B1 (en) | 1970-12-17 | 1971-12-16 | Pharmaceutical compositions |
| IL38375A IL38375A (en) | 1970-12-17 | 1971-12-16 | Anaesthetic compositions comprising a solution of 3alpha-hydroxy-5alpha-pregnane-11,20-dione in organic solvent |
| AU36959/71A AU471022B2 (en) | 1970-12-17 | 1971-12-16 | Pharmaceutical compositions containing 3-hydroxy-5-pregnane 11, 2-dione |
| AT1082571A AT333963B (de) | 1970-12-17 | 1971-12-16 | Verfahren zur herstellung von anasthesierend wirkenden injizierbaren zubereitungen |
| CA130,273A CA970281A (en) | 1970-12-17 | 1971-12-16 | Anesthetic composition containing an anesthetic steroid |
| DE19712162593 DE2162593A1 (de) | 1970-12-17 | 1971-12-16 | Medizinische Zusammensetzungen, enthaltend 3 alpha-Hydroxy-5-alpha-pregnan-11,20-dion |
| FR7145228A FR2118120B1 (enExample) | 1970-12-17 | 1971-12-16 | |
| BE776788A BE776788A (fr) | 1970-12-17 | 1971-12-16 | Preparations pharmaceutiques a activite anesthesique |
| NL7117255A NL7117255A (enExample) | 1970-12-17 | 1971-12-16 | |
| ZA718463A ZA718463B (en) | 1970-12-17 | 1971-12-17 | Improvements in or relating to pharmaceutical preparations having anaesthetic activity |
| US263133A US3917830A (en) | 1970-12-17 | 1972-06-15 | Steroidal anaesthetic composition for intraveneous injection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB6006770A GB1379730A (en) | 1970-12-17 | 1970-12-17 | Pharmaceutical compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1379730A true GB1379730A (en) | 1975-01-08 |
Family
ID=10484946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB6006770A Expired GB1379730A (en) | 1970-12-17 | 1970-12-17 | Pharmaceutical compositions |
Country Status (11)
| Country | Link |
|---|---|
| AT (1) | AT333963B (enExample) |
| AU (1) | AU471022B2 (enExample) |
| BE (1) | BE776788A (enExample) |
| CA (1) | CA970281A (enExample) |
| DE (1) | DE2162593A1 (enExample) |
| FR (1) | FR2118120B1 (enExample) |
| GB (1) | GB1379730A (enExample) |
| IE (1) | IE36705B1 (enExample) |
| IL (1) | IL38375A (enExample) |
| NL (1) | NL7117255A (enExample) |
| ZA (1) | ZA718463B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3893847A4 (en) * | 2018-12-10 | 2022-11-02 | Halo Science LLC | STABLE FORMULATIONS OF ANESTHETICS AND RELATED DOSAGE FORMS |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5581735A (en) * | 1978-12-14 | 1980-06-20 | Kao Corp | Emulsifier composition |
| JP2655190B2 (ja) * | 1989-06-21 | 1997-09-17 | エスエス製薬 株式会社 | コルチコステロイド含有軟膏剤 |
| SE9302295D0 (sv) * | 1993-07-02 | 1993-07-02 | Kabi Pharmacia Ab | New pharmaceutical composition |
| US6787530B1 (en) | 1996-08-23 | 2004-09-07 | Monash University | Use of pregnane-diones as analgesic agents |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL91070C (enExample) * | 1900-01-01 | |||
| DE1262509B (de) * | 1962-04-19 | 1968-03-07 | Hoechst Ag | Verfahren zur Herstellung von waessrigen Loesungen von Steroidhormonen |
| FR6555M (enExample) * | 1967-05-03 | 1968-12-23 |
-
1970
- 1970-12-17 GB GB6006770A patent/GB1379730A/en not_active Expired
-
1971
- 1971-12-16 BE BE776788A patent/BE776788A/xx unknown
- 1971-12-16 NL NL7117255A patent/NL7117255A/xx unknown
- 1971-12-16 AU AU36959/71A patent/AU471022B2/en not_active Expired
- 1971-12-16 IL IL38375A patent/IL38375A/en unknown
- 1971-12-16 IE IE1595/71A patent/IE36705B1/xx unknown
- 1971-12-16 AT AT1082571A patent/AT333963B/de not_active IP Right Cessation
- 1971-12-16 CA CA130,273A patent/CA970281A/en not_active Expired
- 1971-12-16 DE DE19712162593 patent/DE2162593A1/de active Pending
- 1971-12-16 FR FR7145228A patent/FR2118120B1/fr not_active Expired
- 1971-12-17 ZA ZA718463A patent/ZA718463B/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3893847A4 (en) * | 2018-12-10 | 2022-11-02 | Halo Science LLC | STABLE FORMULATIONS OF ANESTHETICS AND RELATED DOSAGE FORMS |
Also Published As
| Publication number | Publication date |
|---|---|
| IL38375A0 (en) | 1972-02-29 |
| ATA1082571A (de) | 1976-04-15 |
| FR2118120B1 (enExample) | 1976-04-16 |
| AU471022B2 (en) | 1976-04-08 |
| ZA718463B (en) | 1973-08-29 |
| BE776788A (fr) | 1972-06-16 |
| CA970281A (en) | 1975-07-01 |
| IE36705B1 (en) | 1977-02-02 |
| AT333963B (de) | 1976-12-27 |
| DE2162593A1 (de) | 1972-07-06 |
| FR2118120A1 (enExample) | 1972-07-28 |
| AU3695971A (en) | 1973-06-21 |
| NL7117255A (enExample) | 1972-06-20 |
| IE36705L (en) | 1972-06-17 |
| IL38375A (en) | 1976-07-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA1080623A (en) | Water-oil emulsion with stearates and glycerides | |
| Patel et al. | Self micro-emulsifying drug delivery system: formulation development and biopharmaceutical evaluation of lipophilic drugs | |
| DE1467848C3 (de) | Unter Druck stehendes, bei Aufhebung des Drucks einen Schaum bildendes Haut-Pflegemittel | |
| DE3212053A1 (de) | Kutanapplizierbare pharmazeutische zusammensetzungen | |
| GB948407A (en) | Intravenously injectable fat emulsions | |
| KR850002953A (ko) | 의약학적 제제의 제조방법 | |
| DK0607231T3 (da) | Anvendelse af en emulsion til fremstilling af et lægemiddel til intravenøs indgivelse til behandling af hudsygdomme | |
| WO1985000106A1 (en) | Improved compositions for the treatment of psoriasis | |
| AU2004257674A1 (en) | Pharmaceutical compositions for topical application | |
| GB1379730A (en) | Pharmaceutical compositions | |
| JP3243564B2 (ja) | 外用貼付剤 | |
| JP2860748B2 (ja) | 安定な酪酸ヒドロコルチゾン含有クリーム剤 | |
| GB880276A (en) | Improvements in or relating to oleaginous pharmaceutical compositions | |
| JPS61293918A (ja) | 皮膚疾患治療用組成物およびその製造法 | |
| JPS5517328A (en) | Insulin-containing emulsion and its preparation | |
| KR850000969A (ko) | 에토 페나메이트-함유 제제의 제조 방법 | |
| IE39113B1 (en) | Pharmaceutical compositions | |
| Talman et al. | Some observations on the use of fatty alcohols and fatty acids to increase the consistency of oil‐in‐water emulsions | |
| JPH0632720A (ja) | 皮膚外用剤 | |
| US3624221A (en) | Method of distributing the sebaceous secretions of the skin | |
| DE352364C (de) | Verfahren zur Herstellung von oeligen medizinischen Loesungen | |
| US3318770A (en) | Intravenously injectable anesthetic composition | |
| JPH09510722A (ja) | 注射可能なジリスロマイシン溶液 | |
| JPS62127B2 (enExample) | ||
| SU15268A1 (ru) | Способ получени растворов камфары |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |