GB1364497A - Therapeutically useful polypeptides - Google Patents
Therapeutically useful polypeptidesInfo
- Publication number
- GB1364497A GB1364497A GB5823571A GB5823571A GB1364497A GB 1364497 A GB1364497 A GB 1364497A GB 5823571 A GB5823571 A GB 5823571A GB 5823571 A GB5823571 A GB 5823571A GB 1364497 A GB1364497 A GB 1364497A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pro
- lys
- thr
- arg
- ser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 6
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 150000001413 amino acids Chemical class 0.000 abstract 5
- 108010071097 threonyl-lysyl-proline Proteins 0.000 abstract 5
- 108010004914 prolylarginine Proteins 0.000 abstract 3
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 abstract 2
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 2
- IESDGNYHXIOKRW-YXMSTPNBSA-N (2s)-2-[[(2s)-1-[(2s)-6-amino-2-[[(2s,3r)-2-amino-3-hydroxybutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid Chemical compound C[C@@H](O)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O IESDGNYHXIOKRW-YXMSTPNBSA-N 0.000 abstract 1
- LEVWYRKDKASIDU-IMJSIDKUSA-N L-cystine Chemical compound [O-]C(=O)[C@@H]([NH3+])CSSC[C@H]([NH3+])C([O-])=O LEVWYRKDKASIDU-IMJSIDKUSA-N 0.000 abstract 1
- 108010053993 N-terminal tetrapeptide cystatin C Proteins 0.000 abstract 1
- 206010057249 Phagocytosis Diseases 0.000 abstract 1
- GVUVRRPYYDHHGK-VQVTYTSYSA-N Pro-Thr Chemical compound C[C@@H](O)[C@@H](C(O)=O)NC(=O)[C@@H]1CCCN1 GVUVRRPYYDHHGK-VQVTYTSYSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004473 Threonine Substances 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 108010068380 arginylarginine Proteins 0.000 abstract 1
- 125000004063 butyryl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 229960003067 cystine Drugs 0.000 abstract 1
- 108010074605 gamma-Globulins Proteins 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 238000010647 peptide synthesis reaction Methods 0.000 abstract 1
- 230000008782 phagocytosis Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000008884 pinocytosis Effects 0.000 abstract 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000010532 solid phase synthesis reaction Methods 0.000 abstract 1
- 125000003696 stearoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 239000000021 stimulant Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9889070A | 1970-12-16 | 1970-12-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1364497A true GB1364497A (en) | 1974-08-21 |
Family
ID=22271422
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5823571A Expired GB1364497A (en) | 1970-12-16 | 1971-12-15 | Therapeutically useful polypeptides |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3778426A (enrdf_load_stackoverflow) |
| JP (1) | JPS6053040B1 (enrdf_load_stackoverflow) |
| CA (1) | CA999851A (enrdf_load_stackoverflow) |
| CH (1) | CH605672A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2124003C2 (enrdf_load_stackoverflow) |
| FR (1) | FR2118134B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1364497A (enrdf_load_stackoverflow) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3966701A (en) * | 1973-11-07 | 1976-06-29 | The Dow Chemical Company | Fibrinogen peptide derivatives |
| US4073890A (en) * | 1974-03-26 | 1978-02-14 | Takeda Chemical Industries, Ltd. | Novel polypeptides |
| US4001199A (en) * | 1974-03-26 | 1977-01-04 | Takeda Chemical Industries, Ltd. | Novel polypeptides useful for treating diabetes and hypercholesteremia |
| US4016259A (en) * | 1974-07-26 | 1977-04-05 | Research Corporation | Contraceptive polypeptides |
| SE407058B (sv) * | 1974-12-05 | 1979-03-12 | Kabi Ab | Nya kromogena enzymsubstrat for serinproteaser |
| DE2602443A1 (de) * | 1975-04-04 | 1976-10-21 | Univ California | Biologisch aktive polypeptide |
| US4169015A (en) * | 1975-07-11 | 1979-09-25 | Ab Kabi | Novel chromogenic thrombin substrates |
| US4061625A (en) * | 1975-07-11 | 1977-12-06 | Ab Kabi | Novel chromogenic thrombin substrates |
| US4181717A (en) * | 1978-09-07 | 1980-01-01 | Research Corporation | Ovulation enhancing peptides |
| IT8021120A0 (it) | 1979-04-02 | 1980-04-01 | Inst Organicheskogo Sinteza Ak | Analogo ciclico del peptide naturale stimolante la fagocitosi: treonile-ciclo (n-lisile-prolile-arginile). |
| US4752601A (en) * | 1983-08-12 | 1988-06-21 | Immunetech Pharmaceuticals | Method of blocking immune complex binding to immunoglobulin FC receptors |
| US4683292A (en) * | 1983-08-12 | 1987-07-28 | Immunetech, Inc. | Immunotherapeutic polypeptide agents which bind to lymphocyte immunoglobulin FC receptors |
| US4585757A (en) * | 1984-07-27 | 1986-04-29 | Texas Tech University Health Sciences Center | Hypotensive active peptides |
| IT1188646B (it) * | 1986-04-09 | 1988-01-20 | Ellem Ind Farmaceutica | Tripeptide ad attivita' immunostimolante |
| GB8807427D0 (en) * | 1988-03-28 | 1988-05-05 | National Biological Standards Board | Peptides |
| IL89770A (en) * | 1988-03-28 | 1994-12-29 | British Tech Group | Analgesic peptides and pharmaceutical compositions containing them and the process for the preparation of some such compounds |
| IT1230712B (it) * | 1989-02-10 | 1991-10-29 | Sclavo Spa | Composizione per vaccini |
| US5028593A (en) * | 1989-08-15 | 1991-07-02 | Board Of Regents, The University Of Texas System | Tuftsin analogs |
| IT1232311B (it) * | 1989-09-04 | 1992-01-28 | Sclavo Spa | Metodo di purificazione di composti a struttura peptidica o pseudo peptidica a basso peso molecolare. |
| GB9211668D0 (en) * | 1992-06-02 | 1992-07-15 | Nycomed Bioreg As | Peptide compounds |
| US7666996B2 (en) * | 2000-03-01 | 2010-02-23 | Peptera Pharmaceuticals Ltd | Casein derived peptides and uses thereof |
| IL134830A0 (en) * | 2000-03-01 | 2001-05-20 | Chay 13 Medical Res Group N V | Peptides and immunostimulatory and anti-bacterial pharmaceutical compositions containing them |
| MXPA04001890A (es) * | 2001-08-30 | 2004-06-18 | Chay 13 Medical Res Group N V | Peptidos derivados de caseina y sus usos en terapia. |
| KR20100059860A (ko) * | 2007-09-11 | 2010-06-04 | 몬도바이오테크 래보래토리즈 아게 | Ｈｂｖ 감염 치료시 치료제로서의 ｎｆ―카파ｂ 저해제 ｓｎ５０ 및 임의의 안지오텐신 ⅲ의 용도 |
| RU2507212C3 (ru) * | 2012-03-28 | 2022-05-04 | Общество С Ограниченной Ответственностью "Айвикс" | Способ получения рекомбинантного пептида и полученный пептид |
| JP6552960B2 (ja) * | 2013-05-28 | 2019-07-31 | アイビックス・リミテッドＩｖｉｘ Ｌｔｄ． | 組換えペプチドを生産するための方法および得られるペプチド |
| RU2626002C1 (ru) | 2016-10-24 | 2017-07-21 | Общество С Ограниченной Ответственностью "Айвикс" | Новая группа пептидов для лечения женской сексуальной дисфункции |
| JP2018118973A (ja) * | 2018-02-23 | 2018-08-02 | アイビックス・リミテッドＩｖｉｘ Ｌｔｄ． | 組換えペプチドを生産するための方法および得られるペプチド |
-
1970
- 1970-12-16 US US00098890A patent/US3778426A/en not_active Expired - Lifetime
-
1971
- 1971-05-14 DE DE2124003A patent/DE2124003C2/de not_active Expired
- 1971-05-14 JP JP46032004A patent/JPS6053040B1/ja active Granted
- 1971-12-10 CA CA129,894A patent/CA999851A/en not_active Expired
- 1971-12-15 GB GB5823571A patent/GB1364497A/en not_active Expired
- 1971-12-16 CH CH1838971A patent/CH605672A5/xx not_active IP Right Cessation
- 1971-12-16 FR FR7145283A patent/FR2118134B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6053040B1 (enrdf_load_stackoverflow) | 1985-11-22 |
| US3778426A (en) | 1973-12-11 |
| CA999851A (en) | 1976-11-16 |
| CH605672A5 (enrdf_load_stackoverflow) | 1978-10-13 |
| FR2118134B1 (enrdf_load_stackoverflow) | 1975-10-10 |
| FR2118134A1 (enrdf_load_stackoverflow) | 1972-07-28 |
| DE2124003A1 (de) | 1972-06-22 |
| DE2124003C2 (de) | 1982-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |