IE35074L - Peptides - Google Patents

Peptides

Info

Publication number
IE35074L
IE35074L IE52471A IE52471A IE35074L IE 35074 L IE35074 L IE 35074L IE 52471 A IE52471 A IE 52471A IE 52471 A IE52471 A IE 52471A IE 35074 L IE35074 L IE 35074L
Authority
IE
Ireland
Prior art keywords
peptides
asn
pro
iii
compounds
Prior art date
Application number
IE52471A
Other versions
IE35074B1 (en
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Priority to IE1891/74A priority Critical patent/IE35075B1/en
Publication of IE35074L publication Critical patent/IE35074L/en
Publication of IE35074B1 publication Critical patent/IE35074B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06156—Dipeptides with the first amino acid being heterocyclic and Trp-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1357121 Peptides E R SQUIBB & SONS Inc 23 April 1971 [28 July 1970] 11048/71 Heading C2C Peptides of the formulae (I), (II) and (III) (where X is Asn, Ser or Nle, n is 0 or 1, Y is Arg, His, Lys or Gly and Z is Asn or Gln) or their derivatives in which at least one carboxyl, amino, guanidino or hydroxy group is protected or a salt thereof are prepared by standard procedures especially by condensing the residue Trp-Pro-Y-Pro with remaining residues or amino acids using a solid phase process. The compounds (I)-(III) inhibit the conversion of angiotenisn (I) to angiotensin (II) and are thus hypotensive agents. The compounds are also biodegradable UV absorbents. Pharmaceutical compositions are in forms for oral and parenteral administration. [GB1357121A]
IE52471A 1970-07-28 1971-04-27 Peptide enzyme inhibitors IE35074B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IE1891/74A IE35075B1 (en) 1970-07-28 1971-04-27 Polypeptide intermediates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5868670A 1970-07-28 1970-07-28

Publications (2)

Publication Number Publication Date
IE35074L true IE35074L (en) 1972-01-28
IE35074B1 IE35074B1 (en) 1975-10-29

Family

ID=22018295

Family Applications (1)

Application Number Title Priority Date Filing Date
IE52471A IE35074B1 (en) 1970-07-28 1971-04-27 Peptide enzyme inhibitors

Country Status (9)

Country Link
JP (1) JPS546556B1 (en)
CA (1) CA946837A (en)
CH (1) CH543483A (en)
DE (1) DE2124451C3 (en)
FR (1) FR2100959B1 (en)
GB (2) GB1357121A (en)
HU (1) HU164325B (en)
IE (1) IE35074B1 (en)
NL (1) NL165655C (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4108886A (en) * 1977-03-11 1978-08-22 E. R. Squibb & Sons, Inc. Thiopropanoylamino acid derivatives
US7498310B1 (en) * 1998-08-13 2009-03-03 Beiersdorf Ag Cosmetic or dermatological preparations comprising oligopeptides for lightening the skin of age marks and/or for preventing tanning of the skin, in particular tanning of the skin caused by UV radiation
WO2006105805A1 (en) * 2005-04-07 2006-10-12 Miso Sabovic Delaying skin ageing and disorders caused by skin ageing by suppression of angiotensin ii production or activity
ES2567706T3 (en) 2007-10-29 2016-04-26 Helix Biomedix Inc. Protective tetrapeptides for skin care

Also Published As

Publication number Publication date
FR2100959B1 (en) 1974-09-06
HU164325B (en) 1974-01-28
NL165655B (en) 1980-12-15
CA946837A (en) 1974-05-07
DE2124451A1 (en) 1972-02-24
JPS546556B1 (en) 1979-03-29
GB1357121A (en) 1974-06-19
CH543483A (en) 1973-10-31
NL7108452A (en) 1972-02-01
NL165655C (en) 1981-05-15
GB1357122A (en) 1974-06-19
DE2124451C3 (en) 1980-09-18
FR2100959A1 (en) 1972-03-24
IE35074B1 (en) 1975-10-29
DE2124451B2 (en) 1979-11-29

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