GB1341121A - Soft gelatin capsule containing a fill of high water content - Google Patents
Soft gelatin capsule containing a fill of high water contentInfo
- Publication number
- GB1341121A GB1341121A GB2153971A GB2153971A GB1341121A GB 1341121 A GB1341121 A GB 1341121A GB 2153971 A GB2153971 A GB 2153971A GB 2153971 A GB2153971 A GB 2153971A GB 1341121 A GB1341121 A GB 1341121A
- Authority
- GB
- United Kingdom
- Prior art keywords
- fill
- water
- soft gelatin
- capsules
- cellulose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title abstract 4
- 239000007903 gelatin capsule Substances 0.000 title abstract 3
- -1 P.V.P. Polymers 0.000 abstract 2
- 239000002775 capsule Substances 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 229920001817 Agar Polymers 0.000 abstract 1
- 108010088751 Albumins Proteins 0.000 abstract 1
- 102000009027 Albumins Human genes 0.000 abstract 1
- 241000416162 Astragalus gummifer Species 0.000 abstract 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 1
- 108010076119 Caseins Proteins 0.000 abstract 1
- 241000206576 Chondrus Species 0.000 abstract 1
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 244000007835 Cyamopsis tetragonoloba Species 0.000 abstract 1
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 244000068988 Glycine max Species 0.000 abstract 1
- 235000010469 Glycine max Nutrition 0.000 abstract 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 229920000881 Modified starch Polymers 0.000 abstract 1
- 239000004368 Modified starch Substances 0.000 abstract 1
- 239000004372 Polyvinyl alcohol Substances 0.000 abstract 1
- 229920002125 Sokalan® Polymers 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 229920001615 Tragacanth Polymers 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000011149 active material Substances 0.000 abstract 1
- 239000008272 agar Substances 0.000 abstract 1
- 235000010419 agar Nutrition 0.000 abstract 1
- 235000010443 alginic acid Nutrition 0.000 abstract 1
- 229920000615 alginic acid Polymers 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 abstract 1
- 239000005018 casein Substances 0.000 abstract 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 abstract 1
- 235000021240 caseins Nutrition 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- AIUDWMLXCFRVDR-UHFFFAOYSA-N dimethyl 2-(3-ethyl-3-methylpentyl)propanedioate Chemical compound CCC(C)(CC)CCC(C(=O)OC)C(=O)OC AIUDWMLXCFRVDR-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 abstract 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229920000609 methyl cellulose Polymers 0.000 abstract 1
- 239000001923 methylcellulose Substances 0.000 abstract 1
- 235000010981 methylcellulose Nutrition 0.000 abstract 1
- 235000019426 modified starch Nutrition 0.000 abstract 1
- 239000001814 pectin Substances 0.000 abstract 1
- 235000010987 pectin Nutrition 0.000 abstract 1
- 229920001277 pectin Polymers 0.000 abstract 1
- 239000004584 polyacrylic acid Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 229920002451 polyvinyl alcohol Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 235000018102 proteins Nutrition 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 235000015424 sodium Nutrition 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- 229920001059 synthetic polymer Polymers 0.000 abstract 1
- 239000000196 tragacanth Substances 0.000 abstract 1
- 235000010487 tragacanth Nutrition 0.000 abstract 1
- 229940116362 tragacanth Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S206/00—Special receptacle or package
- Y10S206/828—Medicinal content
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00055993A US3851051A (en) | 1970-07-17 | 1970-07-17 | Soft gelatin capsule containing high water content fill |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1341121A true GB1341121A (en) | 1973-12-19 |
Family
ID=22001447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2153971A Expired GB1341121A (en) | 1970-07-17 | 1971-04-19 | Soft gelatin capsule containing a fill of high water content |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3851051A (cg-RX-API-DMAC10.html) |
| CA (1) | CA940780A (cg-RX-API-DMAC10.html) |
| DE (1) | DE2135801C3 (cg-RX-API-DMAC10.html) |
| FR (1) | FR2100921B1 (cg-RX-API-DMAC10.html) |
| GB (1) | GB1341121A (cg-RX-API-DMAC10.html) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0106202A3 (en) * | 1982-09-20 | 1985-05-02 | Fujisawa Pharmaceutical Co., Ltd. | New type soft capsule |
| EP0243930A1 (en) * | 1986-05-01 | 1987-11-04 | Pharmacaps, Inc. | Gelatin-encapsulated controlled-release composition |
| US4892766A (en) * | 1987-09-11 | 1990-01-09 | Lilly Industries Limited | Capsules |
| US5037698A (en) * | 1987-01-21 | 1991-08-06 | Lilly Industries Limited | Capsule filling employing hygroscopic components |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5115094B2 (cg-RX-API-DMAC10.html) * | 1972-11-01 | 1976-05-14 | ||
| US4428927A (en) * | 1981-05-11 | 1984-01-31 | R. P. Scherer Corporation | Masticatory soft elastic gelatin capsules and method for the manufacture thereof |
| DE3234331C2 (de) * | 1982-09-16 | 1986-06-05 | A. Nattermann & Cie GmbH, 5000 Köln | Verfahren und Lösungen zum Beschichten von Gelatinekapseln mit magensaftresistenten Überzügen |
| US4609403A (en) * | 1984-03-12 | 1986-09-02 | Warner-Lambert Company | Foam soft gelatin capsules and their method of manufacture |
| GB8507779D0 (en) * | 1985-03-26 | 1985-05-01 | Fujisawa Pharmaceutical Co | Drug carrier |
| DE3529694A1 (de) * | 1985-08-20 | 1987-02-26 | Scherer Gmbh R P | Gelatinekapseln und verfahren zu ihrer herstellung |
| US4795642A (en) * | 1986-05-01 | 1989-01-03 | Pharmacaps, Inc. | Gelatin-encapsulated controlled-release composition |
| US4798725A (en) * | 1986-06-16 | 1989-01-17 | Norwich Eaton Pharmaceuticals, Inc. | Sustained release capsule |
| US4772473A (en) * | 1986-06-16 | 1988-09-20 | Norwich Eaton Pharmaceuticals, Inc. | Nitrofurantoin dosage form |
| US5071643A (en) * | 1986-10-17 | 1991-12-10 | R. P. Scherer Corporation | Solvent system enhancing the solubility of pharmaceuticals for encapsulation |
| US4800083A (en) * | 1986-10-20 | 1989-01-24 | R. P. Scherer Corporation | Sustained release method and product |
| JPH062665B2 (ja) * | 1987-10-06 | 1994-01-12 | 新田ゼラチン株式会社 | ゼラチン組成物 |
| US4935243A (en) * | 1988-12-19 | 1990-06-19 | Pharmacaps, Inc. | Chewable, edible soft gelatin capsule |
| US5063057A (en) * | 1990-09-26 | 1991-11-05 | Elizabeth Arden Co., Division Of Conopco, Inc. | Cosmetic capsules |
| US5141961A (en) * | 1991-06-27 | 1992-08-25 | Richrdson-Vicks Inc. | Process for solubilizing difficulty soluble pharmaceutical actives |
| KR100259989B1 (ko) * | 1991-10-01 | 2000-08-01 | 모리다 가쓰라 | 서방성 마이크로캡슐 제제 및 그의 제조법 |
| NZ244796A (en) * | 1992-08-18 | 1995-05-26 | Scherer Corp R P | Capsule shell of soft gelatin contains a medicament and has a removable tab |
| FR2703908B1 (fr) * | 1993-04-13 | 1995-06-02 | Asta Medica Ag | Forme pharmaceutique pour administration rectale de composés pharmacologiquement actifs. |
| US5431916A (en) * | 1993-04-29 | 1995-07-11 | The Procter & Gamble Company | Pharmaceutical compositions and process of manufacture thereof |
| US5484606A (en) * | 1994-01-24 | 1996-01-16 | The Procter & Gamble Company | Process for reducing the precipitation of difficulty soluble pharmaceutical actives |
| NZ280610A (en) * | 1994-12-29 | 1997-08-22 | Mcneil Ppc Inc | Soft gelatin-like pharmaceutical carrier: gelled polyethylene glycol and dispersed active agent |
| US5660859A (en) * | 1994-12-29 | 1997-08-26 | Mcneil-Ppc, Inc. | Gelling agent for polyethylene glycol |
| US5641512A (en) * | 1995-03-29 | 1997-06-24 | The Procter & Gamble Company | Soft gelatin capsule compositions |
| JP3557579B2 (ja) * | 1998-09-11 | 2004-08-25 | 株式会社三協 | ソフトカプセル剤 |
| WO2002100370A1 (en) * | 2001-06-11 | 2002-12-19 | Warner-Lambert Company Llc | Breath protection microcapsules |
| ITMI20011401A1 (it) * | 2001-07-02 | 2003-01-02 | Altergon Sa | Formulazioni farmaceutiche per ormoni tiroidei |
| ES2302926T5 (es) | 2002-04-25 | 2012-08-23 | Banner Pharmacaps, Inc. | Cápsula blanda masticable |
| DE10309064A1 (de) * | 2003-03-03 | 2004-09-16 | Clariant Gmbh | Polymere Zusammensetzung auf Basis von PVA |
| US9241902B2 (en) | 2003-12-17 | 2016-01-26 | R.P. Scherer Technologies, Llc | Chewable soft capsules containing ungelatinized starch |
| EP1722639A4 (en) * | 2004-01-30 | 2008-01-23 | Univ California | Protected dry composites |
| ES2659538T3 (es) * | 2005-05-02 | 2018-03-16 | 4Life Patents, Llc | Preparaciones de factor de transferencia y métodos asociados |
| US9028882B2 (en) | 2005-05-02 | 2015-05-12 | 4Life Patents, Llc | Nutraceutical gels |
| CA2653953C (en) * | 2006-06-01 | 2015-12-08 | Schering-Plough Healthcare Products, Inc. | Phenylephrine pharmaceutical formulations and compositions for colonic absorption |
| GB0625180D0 (en) * | 2006-12-15 | 2007-01-24 | Mw Encap Ltd | Improved hard shell capsules |
| DE102012221900A1 (de) * | 2012-11-29 | 2014-06-05 | 2LUTION GmbH | Feste Lösungen von Coffein |
| US20160278899A1 (en) * | 2013-11-05 | 2016-09-29 | Synagile Corporation | Devices and methods for continuous drug delivery via the mouth |
| CN113197851A (zh) | 2015-05-06 | 2021-08-03 | 辛纳吉勒公司 | 包含药物粒子的药用悬浮液、用于其配给的装置、以及其使用方法 |
| US9867834B2 (en) | 2015-06-15 | 2018-01-16 | Banner Life Sciences Llc | Non-systemic topical compositions comprising corticosteroids |
| US9877971B2 (en) | 2015-06-15 | 2018-01-30 | Banner Life Sciences Llc | Soft lozenges comprising corticosteroids |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1015251A (en) * | 1963-03-12 | 1965-12-31 | Glaxo Lab Ltd | Aqueous pharmaceutical compositions in capsule form |
| FR1544697A (fr) * | 1966-08-23 | 1968-11-08 | Pfizer & Co C | Perfectionnements apportés aux procédés et dispositifs de mise en capsules |
-
1970
- 1970-07-17 US US00055993A patent/US3851051A/en not_active Expired - Lifetime
-
1971
- 1971-01-21 CA CA103,345A patent/CA940780A/en not_active Expired
- 1971-04-19 GB GB2153971A patent/GB1341121A/en not_active Expired
- 1971-06-22 FR FR7122653A patent/FR2100921B1/fr not_active Expired
- 1971-07-17 DE DE2135801A patent/DE2135801C3/de not_active Expired
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0106202A3 (en) * | 1982-09-20 | 1985-05-02 | Fujisawa Pharmaceutical Co., Ltd. | New type soft capsule |
| EP0243930A1 (en) * | 1986-05-01 | 1987-11-04 | Pharmacaps, Inc. | Gelatin-encapsulated controlled-release composition |
| AU594148B2 (en) * | 1986-05-01 | 1990-03-01 | Pharmacaps, Inc. | Gelatin-encapsulated controlled-release composition |
| US5037698A (en) * | 1987-01-21 | 1991-08-06 | Lilly Industries Limited | Capsule filling employing hygroscopic components |
| US4892766A (en) * | 1987-09-11 | 1990-01-09 | Lilly Industries Limited | Capsules |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2135801C3 (de) | 1979-10-25 |
| DE2135801A1 (de) | 1972-01-27 |
| DE2135801B2 (de) | 1979-03-01 |
| CA940780A (en) | 1974-01-29 |
| FR2100921B1 (cg-RX-API-DMAC10.html) | 1975-06-06 |
| US3851051A (en) | 1974-11-26 |
| FR2100921A1 (cg-RX-API-DMAC10.html) | 1972-03-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |