GB1215132A - Physiologically active amine derivatives of thiophthalane - Google Patents
Physiologically active amine derivatives of thiophthalaneInfo
- Publication number
- GB1215132A GB1215132A GB44560/67A GB4456067A GB1215132A GB 1215132 A GB1215132 A GB 1215132A GB 44560/67 A GB44560/67 A GB 44560/67A GB 4456067 A GB4456067 A GB 4456067A GB 1215132 A GB1215132 A GB 1215132A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- reacting
- acid
- alkylene
- thiophthalane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001412 amines Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 11
- 150000001875 compounds Chemical class 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000002947 alkylene group Chemical group 0.000 abstract 3
- 229910010082 LiAlH Inorganic materials 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
- RJAMFGHYWNKPBY-UHFFFAOYSA-N 1-(2-benzylsulfanylpropan-2-yl)-2-chlorobenzene Chemical compound C=1C=CC=C(Cl)C=1C(C)(C)SCC1=CC=CC=C1 RJAMFGHYWNKPBY-UHFFFAOYSA-N 0.000 abstract 1
- IFOKAMVJZHDRBI-UHFFFAOYSA-N 1-[2-[hydroxy(phenyl)methyl]phenyl]ethanone Chemical compound CC(=O)C1=CC=CC=C1C(O)C1=CC=CC=C1 IFOKAMVJZHDRBI-UHFFFAOYSA-N 0.000 abstract 1
- UALUYGFVNLQVFT-UHFFFAOYSA-N 2-(2-chlorophenyl)propan-2-ol Chemical compound CC(C)(O)C1=CC=CC=C1Cl UALUYGFVNLQVFT-UHFFFAOYSA-N 0.000 abstract 1
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- IKJFMKTYCKZJFM-UHFFFAOYSA-N 2-[2-(2-chlorophenyl)propan-2-ylsulfanyl]acetic acid Chemical compound C(=O)(O)CSC(C)(C)C1=C(C=CC=C1)Cl IKJFMKTYCKZJFM-UHFFFAOYSA-N 0.000 abstract 1
- FGTYTUFKXYPTML-UHFFFAOYSA-N 2-benzoylbenzoic acid Chemical compound OC(=O)C1=CC=CC=C1C(=O)C1=CC=CC=C1 FGTYTUFKXYPTML-UHFFFAOYSA-N 0.000 abstract 1
- SQFMIHCARVMICF-UHFFFAOYSA-N 3-phenyl-3h-2-benzofuran-1-one Chemical compound C12=CC=CC=C2C(=O)OC1C1=CC=CC=C1 SQFMIHCARVMICF-UHFFFAOYSA-N 0.000 abstract 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- MHYYURNPGROKGA-UHFFFAOYSA-N N,N-dimethyl-4-phenyl-4-(2-prop-1-en-2-ylphenyl)but-3-en-1-amine Chemical compound C(=C)(C)C1=C(C=CC=C1)C(=CCCN(C)C)C1=CC=CC=C1 MHYYURNPGROKGA-UHFFFAOYSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- HSDAJNMJOMSNEV-UHFFFAOYSA-N benzyl chloroformate Chemical compound ClC(=O)OCC1=CC=CC=C1 HSDAJNMJOMSNEV-UHFFFAOYSA-N 0.000 abstract 1
- UENWRTRMUIOCKN-UHFFFAOYSA-N benzyl thiol Chemical compound SCC1=CC=CC=C1 UENWRTRMUIOCKN-UHFFFAOYSA-N 0.000 abstract 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- DDKMFOUTRRODRE-UHFFFAOYSA-N chloromethanone Chemical compound Cl[C]=O DDKMFOUTRRODRE-UHFFFAOYSA-N 0.000 abstract 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
- QILSFLSDHQAZET-UHFFFAOYSA-N diphenylmethanol Chemical compound C=1C=CC=CC=1C(O)C1=CC=CC=C1 QILSFLSDHQAZET-UHFFFAOYSA-N 0.000 abstract 1
- 125000004494 ethyl ester group Chemical group 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- VXWPONVCMVLXBW-UHFFFAOYSA-M magnesium;carbanide;iodide Chemical compound [CH3-].[Mg+2].[I-] VXWPONVCMVLXBW-UHFFFAOYSA-M 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- PAKXZQDZFQVWDQ-UHFFFAOYSA-N phenyl-(2-prop-1-en-2-ylphenyl)methanone Chemical compound CC(=C)C1=CC=CC=C1C(=O)C1=CC=CC=C1 PAKXZQDZFQVWDQ-UHFFFAOYSA-N 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- CWERGRDVMFNCDR-UHFFFAOYSA-N thioglycolic acid Chemical compound OC(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/72—Benzo[c]thiophenes; Hydrogenated benzo[c]thiophenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB44560/67A GB1215132A (en) | 1967-01-16 | 1967-09-29 | Physiologically active amine derivatives of thiophthalane |
| AT1184968A AT276374B (de) | 1967-01-16 | 1968-01-09 | Verfahren zur Herstellung von neuen 1-Aminoalkyl-thiophthalanen und deren Säureadditionssalzen |
| AT1185068A AT276375B (de) | 1967-01-16 | 1968-01-09 | Verfahren zur Herstellung von neuen 1-Aminoalkyl-thiophthalanen und deren Säureadditionssalzen |
| AT19068A AT276373B (de) | 1967-01-16 | 1968-01-09 | Verfahren zur Herstellung von neuen 1-Aminoalkyl-thiophthalanen und deren Säureadditionssalzen |
| BE709229D BE709229A (enrdf_load_stackoverflow) | 1967-01-16 | 1968-01-11 | |
| DE19681668925 DE1668925B1 (de) | 1967-01-16 | 1968-01-12 | Benzo[c]thiacyclopentene sowie diese enthaltende psychotherapeutische Mittel |
| CH1085370A CH522667A (de) | 1967-01-16 | 1968-01-12 | Verfahren zur Herstellung von neuen 1-Aminoalkyl-thiophthalanen und deren Säureadditionssalzen |
| CH45968A CH510041A (de) | 1967-01-16 | 1968-01-12 | Verfahren zur Herstellung von neuen 1-Aminoalkyl-thiophthalanen bzw. deren Säureadditionssalzen und deren Verwendung |
| ES349217A ES349217A1 (es) | 1967-01-13 | 1968-01-12 | Espectrometro electrooptico para la obtencion del un metodo para la preparacion de tioftalanos. trazado rapido y con elevada resolucion del perfil espectral de una fuente luminosa. |
| CH1085470A CH516577A (de) | 1967-01-16 | 1968-01-12 | Verfahren zur Herstellung von neuen 1-Aminoalkyl-Thiophthalanen und deren Säureadditionssalzen |
| DK11868A DK128813B (da) | 1967-01-16 | 1968-01-15 | Analogifremgangsmåde til fremstilling af basisk substituerede thiophthalaner eller syreadditionssalte deraf. |
| NO16068A NO121670B (enrdf_load_stackoverflow) | 1967-01-16 | 1968-01-15 | |
| NL6800637A NL6800637A (enrdf_load_stackoverflow) | 1967-01-16 | 1968-01-16 | |
| FR1583194D FR1583194A (enrdf_load_stackoverflow) | 1967-01-16 | 1968-01-16 | |
| SE55968A SE351652B (enrdf_load_stackoverflow) | 1967-01-16 | 1968-01-16 | |
| FI11568A FI49978C (fi) | 1967-01-16 | 1968-01-16 | Menetelmä terapeuttisesti aktiivisten, emäksisesti substituoitujen tio ftalaanien tai niiden happoadditiosuolojen valmistamiseksi. |
| FR136254A FR8378M (enrdf_load_stackoverflow) | 1967-01-16 | 1968-01-16 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB232767 | 1967-01-16 | ||
| GB44560/67A GB1215132A (en) | 1967-01-16 | 1967-09-29 | Physiologically active amine derivatives of thiophthalane |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1215132A true GB1215132A (en) | 1970-12-09 |
Family
ID=26237442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB44560/67A Expired GB1215132A (en) | 1967-01-13 | 1967-09-29 | Physiologically active amine derivatives of thiophthalane |
Country Status (11)
| Country | Link |
|---|---|
| AT (3) | AT276373B (enrdf_load_stackoverflow) |
| BE (1) | BE709229A (enrdf_load_stackoverflow) |
| CH (2) | CH522667A (enrdf_load_stackoverflow) |
| DE (1) | DE1668925B1 (enrdf_load_stackoverflow) |
| DK (1) | DK128813B (enrdf_load_stackoverflow) |
| FI (1) | FI49978C (enrdf_load_stackoverflow) |
| FR (2) | FR8378M (enrdf_load_stackoverflow) |
| GB (1) | GB1215132A (enrdf_load_stackoverflow) |
| NL (1) | NL6800637A (enrdf_load_stackoverflow) |
| NO (1) | NO121670B (enrdf_load_stackoverflow) |
| SE (1) | SE351652B (enrdf_load_stackoverflow) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2548186A1 (fr) * | 1983-07-01 | 1985-01-04 | Delalande Sa | Nouveaux derives des thiophtalide et isobenzofuranethione 3-amines, leur procede de preparation et leur application en therapeutique |
| AT387183B (de) * | 1983-10-05 | 1988-12-12 | Distropat Ag | Verfahren zum anschaeumen eines teiles aus polyurethan-schaumstoff an wenigstens einen teil aus holz oder holzaehnlichen werkstoffen |
-
1967
- 1967-09-29 GB GB44560/67A patent/GB1215132A/en not_active Expired
-
1968
- 1968-01-09 AT AT19068A patent/AT276373B/de active
- 1968-01-09 AT AT1184968A patent/AT276374B/de active
- 1968-01-09 AT AT1185068A patent/AT276375B/de active
- 1968-01-11 BE BE709229D patent/BE709229A/xx unknown
- 1968-01-12 CH CH1085370A patent/CH522667A/de not_active IP Right Cessation
- 1968-01-12 CH CH45968A patent/CH510041A/de not_active IP Right Cessation
- 1968-01-12 DE DE19681668925 patent/DE1668925B1/de active Pending
- 1968-01-15 DK DK11868A patent/DK128813B/da unknown
- 1968-01-15 NO NO16068A patent/NO121670B/no unknown
- 1968-01-16 FI FI11568A patent/FI49978C/fi active
- 1968-01-16 FR FR136254A patent/FR8378M/fr not_active Expired
- 1968-01-16 SE SE55968A patent/SE351652B/xx unknown
- 1968-01-16 FR FR1583194D patent/FR1583194A/fr not_active Expired
- 1968-01-16 NL NL6800637A patent/NL6800637A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH510041A (de) | 1971-07-15 |
| BE709229A (enrdf_load_stackoverflow) | 1968-07-11 |
| AT276373B (de) | 1969-11-25 |
| FR8378M (enrdf_load_stackoverflow) | 1971-03-01 |
| DE1668925B1 (de) | 1972-06-08 |
| FI49978C (fi) | 1975-11-10 |
| NO121670B (enrdf_load_stackoverflow) | 1971-03-29 |
| FR1583194A (enrdf_load_stackoverflow) | 1969-10-24 |
| FI49978B (enrdf_load_stackoverflow) | 1975-07-31 |
| SE351652B (enrdf_load_stackoverflow) | 1972-12-04 |
| AT276375B (de) | 1969-11-25 |
| DK128813B (da) | 1974-07-08 |
| CH522667A (de) | 1972-05-15 |
| NL6800637A (enrdf_load_stackoverflow) | 1968-07-17 |
| AT276374B (de) | 1969-11-25 |
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