GB1131007A - Improvements in or relating to aqueous solutions of oxytetracycline - Google Patents

Improvements in or relating to aqueous solutions of oxytetracycline

Info

Publication number
GB1131007A
GB1131007A GB22620/67A GB2262067A GB1131007A GB 1131007 A GB1131007 A GB 1131007A GB 22620/67 A GB22620/67 A GB 22620/67A GB 2262067 A GB2262067 A GB 2262067A GB 1131007 A GB1131007 A GB 1131007A
Authority
GB
United Kingdom
Prior art keywords
oxytetracycline
magnesium
aqueous solutions
sodium
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB22620/67A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM Delft BV
Original Assignee
Koninklijke Nederlandsche Gist en Spiritusfabriek BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Nederlandsche Gist en Spiritusfabriek BV filed Critical Koninklijke Nederlandsche Gist en Spiritusfabriek BV
Publication of GB1131007A publication Critical patent/GB1131007A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • A61K31/787Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79Polymers of vinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
GB22620/67A 1966-05-31 1967-05-16 Improvements in or relating to aqueous solutions of oxytetracycline Expired GB1131007A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL6607516A NL6607516A (cg-RX-API-DMAC7.html) 1966-05-31 1966-05-31

Publications (1)

Publication Number Publication Date
GB1131007A true GB1131007A (en) 1968-10-16

Family

ID=19796753

Family Applications (1)

Application Number Title Priority Date Filing Date
GB22620/67A Expired GB1131007A (en) 1966-05-31 1967-05-16 Improvements in or relating to aqueous solutions of oxytetracycline

Country Status (22)

Country Link
US (1) US3557280A (cg-RX-API-DMAC7.html)
JP (1) JPS5010373B1 (cg-RX-API-DMAC7.html)
AT (1) AT272522B (cg-RX-API-DMAC7.html)
BE (1) BE699091A (cg-RX-API-DMAC7.html)
CH (1) CH490087A (cg-RX-API-DMAC7.html)
CS (1) CS151454B2 (cg-RX-API-DMAC7.html)
DE (1) DE1617576C3 (cg-RX-API-DMAC7.html)
DK (1) DK117587B (cg-RX-API-DMAC7.html)
ES (1) ES340956A1 (cg-RX-API-DMAC7.html)
FI (1) FI43622B (cg-RX-API-DMAC7.html)
FR (1) FR5953M (cg-RX-API-DMAC7.html)
GB (1) GB1131007A (cg-RX-API-DMAC7.html)
GR (1) GR33861B (cg-RX-API-DMAC7.html)
IL (1) IL28009A (cg-RX-API-DMAC7.html)
IT (1) IT1140250B (cg-RX-API-DMAC7.html)
LU (1) LU53788A1 (cg-RX-API-DMAC7.html)
MY (1) MY7100015A (cg-RX-API-DMAC7.html)
NL (1) NL6607516A (cg-RX-API-DMAC7.html)
NO (1) NO126298B (cg-RX-API-DMAC7.html)
SE (1) SE354417B (cg-RX-API-DMAC7.html)
SU (1) SU510986A3 (cg-RX-API-DMAC7.html)
YU (1) YU31326B (cg-RX-API-DMAC7.html)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5418330B2 (cg-RX-API-DMAC7.html) * 1973-03-16 1979-07-06
US3966905A (en) * 1973-05-29 1976-06-29 Barnes-Hind Pharmaceuticals, Inc. Stabilized catechol amine solutions
US3929989A (en) * 1974-06-14 1975-12-30 Wendt Lab Inc Stable suspension of calcium-magnesium oxytetracycline for intrauterine administration in treatment of bovine metritis
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
DE2602363C2 (de) * 1976-01-22 1984-04-12 Bayer Ag, 5090 Leverkusen Wäßrige, injizierbare Niclofolan- Formulierungen
GB1592053A (en) * 1976-12-16 1981-07-01 Norbrook Lab Ltd Oxytetracycline compositions
US4213963A (en) * 1978-12-14 1980-07-22 Janssen Pharmaceutica N.V. Fluspirilene-containing compositions
US4259331A (en) * 1979-04-16 1981-03-31 Pfizer Inc. Oxytetracycline compositions
US4386083A (en) * 1980-04-10 1983-05-31 Walter Hacke Injectable oxytetracycline compositions
US4399127A (en) * 1980-04-10 1983-08-16 Diamond Shamrock Corporation Injectable oxytetracycline compositions
IE74244B1 (en) * 1985-10-01 1997-07-16 Bimeda Res Dev Ltd A process for preparing an antibiotic composition
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
US6756365B2 (en) * 1991-11-06 2004-06-29 Trustees Of Tufts College Reducing tetracycline resistance in living cells
EP0626171A1 (de) * 1993-05-26 1994-11-30 Winfried Dörnhöfer Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere
US6383515B2 (en) 1999-05-28 2002-05-07 Sawyer Maryjean Solvent system for enhancing solubility
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
CZ301835B6 (cs) 1999-09-14 2010-07-07 Trustees Of Tufts College Zpusob prípravy 7-, 9- nebo 13- substituované tetracyklinové slouceniny, reaktivní tetracyklinový chemický komplex a tetracyklinová sloucenina substituovaná v poloze 7 nebo 9
CA2397863A1 (en) * 2000-01-24 2001-07-26 Trustees Of Tufts College Tetracycline compounds for treatment of cryptosporidium parvum related disorders
KR20030007489A (ko) * 2000-03-31 2003-01-23 트러스티즈 오브 터프츠 칼리지 7- 및 9-카르바메이트, 우레아, 티오우레아,티오카르바메이트 및 헤테로아릴-아미노 치환된테트라사이클린 화합물
EP2308863A1 (en) * 2000-05-15 2011-04-13 Paratek Pharmaceuticals, Inc. 7-substituted fused ring tetracycline compounds
AU2001268475A1 (en) * 2000-06-16 2002-01-02 Trustees Of Tufts College 7-phenyl-substituted tetracycline compounds
US20040224927A1 (en) * 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
CN1690047B (zh) 2000-07-07 2010-10-06 塔夫茨大学信托人 9-取代的二甲胺四环素化合物
US7094806B2 (en) * 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
CN102336679A (zh) 2000-07-07 2012-02-01 塔夫茨大学信托人 7-取代的四环素化合物
JP4963771B2 (ja) 2000-07-07 2012-06-27 トラスティーズ・オブ・タフツ・カレッジ 7、8および9−置換テトラサイクリン化合物
AU2001271616A1 (en) 2000-07-07 2002-01-21 Paratek Pharmaceuticals, Inc 13-substituted methacycline compounds
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
EA201000388A1 (ru) 2001-03-13 2010-10-29 Пэрэтек Фамэсьютикэлс, Инк. Замещенные соединения тетрациклина (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния субъекта
WO2002072506A2 (en) * 2001-03-13 2002-09-19 Paratek Pharmaceuticals, Inc. 7-pyrollyl tetracycline compounds and methods of use thereof
US6841546B2 (en) 2001-03-14 2005-01-11 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as antifungal agents
EP1381372A2 (en) 2001-03-14 2004-01-21 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as synergistic antifungal agents
EP2186793A1 (en) 2001-04-24 2010-05-19 Paratek Pharmaceuticals, Inc. Substituted Tetracycline Compounds
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
EP2311799A1 (en) * 2002-01-08 2011-04-20 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
EA201000491A1 (ru) 2002-03-08 2010-08-30 Паратек Фармасьютикалс, Инк. Аминометилзамещенные тетрациклиновые соединения
AU2003218243B2 (en) 2002-03-21 2010-04-01 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
EA012136B1 (ru) 2002-07-12 2009-08-28 Пэрэтек Фамэсьютикэлс, Инк. Замещенные соединения тетрациклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта
CA2502464A1 (en) 2002-10-24 2004-05-06 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
AU2003261633A1 (en) * 2003-02-12 2004-09-06 R And P Korea Co., Ltd. Solvent system of hardly soluble drug with improved elution rate
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
JP4738333B2 (ja) 2003-07-09 2011-08-03 パラテック ファーマシューティカルズ インコーポレイテッド 9−アミノメチルテトラサイクリン化合物のプロドラッグ
KR101228706B1 (ko) 2003-07-09 2013-02-01 파라테크 파마슈티컬스, 인크. 치환된 테트라시클린 화합물
US7786099B2 (en) * 2004-01-15 2010-08-31 Paratek Pharmaceuticals, Inc. Aromatic a-ring derivatives of tetracycline compounds
TWI261038B (en) * 2004-08-11 2006-09-01 Bo-Cheng Chen Bicycle gear-shifting handgrip
EP2284152A3 (en) 2004-10-25 2011-10-05 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
EP2301912A3 (en) 2004-10-25 2012-07-11 Paratek Pharmaceuticals, Inc. 4-aminotetracyclines and methods of use thereof
EP1848685A1 (en) 2005-02-04 2007-10-31 Paratek Pharmaceuticals, Inc. 11a, 12-derivatives of tetracycline compounds
DE102005012595A1 (de) * 2005-03-18 2006-09-21 Lanxess Deutschland Gmbh Herstellung von Tri(chlorpropyl)phosphat
WO2007014154A2 (en) * 2005-07-21 2007-02-01 Paratek Pharmaceuticals, Inc. 10-substituted tetracyclines and methods of use thereof
WO2007035448A2 (en) * 2005-09-19 2007-03-29 Albemarle Corporation Highly concentrated pourable aqueous solutions of potassium ibuprofen their preparation and their uses
AU2007208214B2 (en) 2006-01-24 2013-02-14 Paratek Pharmaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
CN101489987A (zh) * 2006-04-17 2009-07-22 特瓦制药工业有限公司 四环素衍生物的分离
DE202007019460U1 (de) * 2006-04-24 2012-10-24 Teva Pharmaceutical Industries Ltd. Kristalline Tigecyclin-Formen
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
AU2007249695A1 (en) * 2006-05-15 2007-11-22 Paratek Pharmaceuticals, Inc. Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
WO2008045507A2 (en) 2006-10-11 2008-04-17 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of bacillus anthracis infections
ES2463457T3 (es) 2006-12-21 2014-05-28 Paratek Pharmaceuticals, Inc. Derivados de la tetraciclina para el tratamiento de infecciones bacterianas, virales y parasitarias
ES2701725T3 (es) 2006-12-21 2019-02-25 Paratek Pharm Innc Compuestos de tetraciclina sustituida para el tratamiento de trastornos inflamatorios de la piel
EP2144614A1 (en) * 2007-04-12 2010-01-20 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
JP2010525069A (ja) 2007-04-27 2010-07-22 パラテック ファーマシューティカルズ インコーポレイテッド アミノアルキルテトラサイクリン化合物の合成方法および精製方法
EP2176216B1 (en) 2007-07-06 2012-04-25 Paratek Pharmaceuticals, Inc. Methods for synthesizing 9-substituted minocycline
US20090253660A1 (en) 2008-03-05 2009-10-08 Paratek Pharmaceuticals, Inc. Minocycline Compounds and Methods of Use Thereof
PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
US20100022483A1 (en) * 2008-04-14 2010-01-28 Paratek Pharmaceuticals, Inc. Substituted Tetracycline Compounds
TW202436282A (zh) * 2008-05-19 2024-09-16 美商Prtk Spv2公司 四環素化合物之甲苯磺酸鹽及同素異形體
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
US9629806B2 (en) * 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
EP2341771A4 (en) * 2008-09-19 2012-08-15 Paratek Pharm Innc TETRACYCLINE COMPOUNDS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS AND RELATED THERAPEUTIC METHODS
JP2012523438A (ja) 2009-04-10 2012-10-04 タフツ メディカル センター インコーポレイテッド メタロプロテイナーゼ−1(mmp−1)によるpar−1活性化
US9255068B2 (en) 2011-05-12 2016-02-09 Warner Chilcott Company, Llc Crystalline salts of (4S,4AS,5AR,12AS)-4-dimethylamino-3,10,12,12A-tetrahydroxy-7-[methoxy(methyl)amino)-methyl] acid amide and methods of using the same
MX2019005070A (es) 2016-11-01 2019-09-23 Paratek Pharm Innc Compuestos de 9-aminometil minociclina y su uso en el tratamiento de neumonía bacteriana adquirida en la comunidad (cabp).
EP3654988B1 (en) 2017-07-21 2023-09-06 Almirall, LLC Sarecycline for the treatment of non-inflammatory acne lesions

Also Published As

Publication number Publication date
GR33861B (el) 1968-02-09
YU31326B (en) 1973-04-30
AT272522B (de) 1969-07-10
SU510986A3 (ru) 1976-04-15
CS151454B2 (cg-RX-API-DMAC7.html) 1973-10-19
MY7100015A (en) 1971-12-31
BE699091A (cg-RX-API-DMAC7.html) 1967-11-27
DK117587B (da) 1970-05-11
ES340956A1 (es) 1968-06-16
JPS5010373B1 (cg-RX-API-DMAC7.html) 1975-04-21
NL6607516A (cg-RX-API-DMAC7.html) 1967-12-01
IT1140250B (it) 1986-09-24
FI43622B (cg-RX-API-DMAC7.html) 1971-02-01
FR5953M (cg-RX-API-DMAC7.html) 1968-04-16
LU53788A1 (cg-RX-API-DMAC7.html) 1967-07-31
CH490087A (de) 1970-05-15
DE1617576C3 (de) 1980-12-11
SE354417B (cg-RX-API-DMAC7.html) 1973-03-12
DE1617576A1 (de) 1972-04-27
IL28009A (en) 1970-08-19
NO126298B (cg-RX-API-DMAC7.html) 1973-01-22
US3557280A (en) 1971-01-19
DE1617576B2 (de) 1980-04-10

Similar Documents

Publication Publication Date Title
GB1131007A (en) Improvements in or relating to aqueous solutions of oxytetracycline
GB1226394A (cg-RX-API-DMAC7.html)
GB1494558A (en) Oxytetracycline solution for parenteral peroral and local administration and processes for the production thereof
AU576204B2 (en) Aqueous, injectable solutions of cis-platimum
ES399906A1 (es) Procedimiento para componer preparados colorantes.
ES450075A1 (es) Un metodo de preparacion de derivados de bis-triazinilamino-estilbeno.
GB1278117A (en) Stabilized 2-pam solutions
GB1213808A (en) Photographic processing compositions
GB1211302A (en) Barium sulphate reflectance standards
GB1289693A (cg-RX-API-DMAC7.html)
GB1331190A (en) X-ray contrast composition containing barium sulphate
GB1427882A (en) Oxytetracycline solutions
GB1243252A (en) Stable poliomyelitis vaccines and process for their manufacture
JPS5675438A (en) Method for stabilizing aqueous solution of cyanocobalamin
GB1419933A (en) Preparation of methylcobalamine
GB1438217A (en) 1-alkyl-5-nitro-imidaolyl-2-alkyl-pyridyl compounds and process for preparing them
KR860002269A (ko) 비경구용 액제의 제조방법
GB1057951A (en) Improvements in photographic colour processes
GB1125349A (en) Soluble salts of ellagic acid
GB1361491A (en) Process for the production of oxytetracycline solutions
GB1291678A (en) L-dopa and derivatives
GB1222449A (en) Process for preparing pure human albumin from solutions containing haemopigments
GB1342643A (en) Thioacetanilide derivatives
GB1135597A (en) Antacid material
ES8203016A1 (es) Un procedimiento para la preparacion de una solucion acuosa inyectable de sales de metales alcalinas de acido canrenoicoy de furosemida.