IT1140250B - Procedimento per la preparazione di soluzioni stabili di ossitetraciclina in acqua, adatte per somministrazioni per via parenterale ed orale - Google Patents

Procedimento per la preparazione di soluzioni stabili di ossitetraciclina in acqua, adatte per somministrazioni per via parenterale ed orale

Info

Publication number
IT1140250B
IT1140250B IT37118/67A IT3711867A IT1140250B IT 1140250 B IT1140250 B IT 1140250B IT 37118/67 A IT37118/67 A IT 37118/67A IT 3711867 A IT3711867 A IT 3711867A IT 1140250 B IT1140250 B IT 1140250B
Authority
IT
Italy
Prior art keywords
oxytracycline
parenteral
procedure
preparation
water
Prior art date
Application number
IT37118/67A
Other languages
English (en)
Italian (it)
Original Assignee
Koninklijke Gist Spiritus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Gist Spiritus filed Critical Koninklijke Gist Spiritus
Application granted granted Critical
Publication of IT1140250B publication Critical patent/IT1140250B/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • A61K31/787Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79Polymers of vinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IT37118/67A 1966-05-31 1967-05-30 Procedimento per la preparazione di soluzioni stabili di ossitetraciclina in acqua, adatte per somministrazioni per via parenterale ed orale IT1140250B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL6607516A NL6607516A (cg-RX-API-DMAC7.html) 1966-05-31 1966-05-31

Publications (1)

Publication Number Publication Date
IT1140250B true IT1140250B (it) 1986-09-24

Family

ID=19796753

Family Applications (1)

Application Number Title Priority Date Filing Date
IT37118/67A IT1140250B (it) 1966-05-31 1967-05-30 Procedimento per la preparazione di soluzioni stabili di ossitetraciclina in acqua, adatte per somministrazioni per via parenterale ed orale

Country Status (22)

Country Link
US (1) US3557280A (cg-RX-API-DMAC7.html)
JP (1) JPS5010373B1 (cg-RX-API-DMAC7.html)
AT (1) AT272522B (cg-RX-API-DMAC7.html)
BE (1) BE699091A (cg-RX-API-DMAC7.html)
CH (1) CH490087A (cg-RX-API-DMAC7.html)
CS (1) CS151454B2 (cg-RX-API-DMAC7.html)
DE (1) DE1617576C3 (cg-RX-API-DMAC7.html)
DK (1) DK117587B (cg-RX-API-DMAC7.html)
ES (1) ES340956A1 (cg-RX-API-DMAC7.html)
FI (1) FI43622B (cg-RX-API-DMAC7.html)
FR (1) FR5953M (cg-RX-API-DMAC7.html)
GB (1) GB1131007A (cg-RX-API-DMAC7.html)
GR (1) GR33861B (cg-RX-API-DMAC7.html)
IL (1) IL28009A (cg-RX-API-DMAC7.html)
IT (1) IT1140250B (cg-RX-API-DMAC7.html)
LU (1) LU53788A1 (cg-RX-API-DMAC7.html)
MY (1) MY7100015A (cg-RX-API-DMAC7.html)
NL (1) NL6607516A (cg-RX-API-DMAC7.html)
NO (1) NO126298B (cg-RX-API-DMAC7.html)
SE (1) SE354417B (cg-RX-API-DMAC7.html)
SU (1) SU510986A3 (cg-RX-API-DMAC7.html)
YU (1) YU31326B (cg-RX-API-DMAC7.html)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5418330B2 (cg-RX-API-DMAC7.html) * 1973-03-16 1979-07-06
US3966905A (en) * 1973-05-29 1976-06-29 Barnes-Hind Pharmaceuticals, Inc. Stabilized catechol amine solutions
US3929989A (en) * 1974-06-14 1975-12-30 Wendt Lab Inc Stable suspension of calcium-magnesium oxytetracycline for intrauterine administration in treatment of bovine metritis
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
DE2602363C2 (de) * 1976-01-22 1984-04-12 Bayer Ag, 5090 Leverkusen Wäßrige, injizierbare Niclofolan- Formulierungen
GB1592053A (en) * 1976-12-16 1981-07-01 Norbrook Lab Ltd Oxytetracycline compositions
US4213963A (en) * 1978-12-14 1980-07-22 Janssen Pharmaceutica N.V. Fluspirilene-containing compositions
US4259331A (en) * 1979-04-16 1981-03-31 Pfizer Inc. Oxytetracycline compositions
US4399127A (en) * 1980-04-10 1983-08-16 Diamond Shamrock Corporation Injectable oxytetracycline compositions
US4386083A (en) * 1980-04-10 1983-05-31 Walter Hacke Injectable oxytetracycline compositions
IE74244B1 (en) * 1985-10-01 1997-07-16 Bimeda Res Dev Ltd A process for preparing an antibiotic composition
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
US6756365B2 (en) * 1991-11-06 2004-06-29 Trustees Of Tufts College Reducing tetracycline resistance in living cells
EP0626171A1 (de) * 1993-05-26 1994-11-30 Winfried Dörnhöfer Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere
US6383515B2 (en) 1999-05-28 2002-05-07 Sawyer Maryjean Solvent system for enhancing solubility
US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
EP1666454B1 (en) * 1999-09-14 2011-09-07 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
EP1263442A1 (en) * 2000-01-24 2002-12-11 Trustees Of Tufts College TETRACYCLINE COMPOUNDS FOR TREATMENT OF i CRYPTOSPORIDIUM PARVUM /i RELATED DISORDERS
CA2404628A1 (en) 2000-03-31 2001-10-11 Stuart B. Levy 7-and 9-carbamate, urea, thiourea, thiocarbamate, and heteroaryl-amino substituted tetracycline compounds
ATE264295T1 (de) * 2000-05-15 2004-04-15 Paratek Pharm Innc 7-substituierte kondensierte ring-tetrazyclin- verbindungen
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
US20040224927A1 (en) 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
US20020128238A1 (en) * 2000-06-16 2002-09-12 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
MXPA03000056A (es) * 2000-07-07 2003-07-14 Tufts College Compuestos de tetraciclina sustituidos en posicion 7.
JP4963771B2 (ja) 2000-07-07 2012-06-27 トラスティーズ・オブ・タフツ・カレッジ 7、8および9−置換テトラサイクリン化合物
CN1690047B (zh) 2000-07-07 2010-10-06 塔夫茨大学信托人 9-取代的二甲胺四环素化合物
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
EP1301465A2 (en) 2000-07-07 2003-04-16 Trustees Of Tufts College 13-substituted methacycline compounds
US7094806B2 (en) 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
EA201000388A1 (ru) 2001-03-13 2010-10-29 Пэрэтек Фамэсьютикэлс, Инк. Замещенные соединения тетрациклина (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния субъекта
WO2002072506A2 (en) * 2001-03-13 2002-09-19 Paratek Pharmaceuticals, Inc. 7-pyrollyl tetracycline compounds and methods of use thereof
CA2440757A1 (en) 2001-03-14 2002-09-19 Michael Draper Substituted tetracycline compounds as synergistic antifungal agents
JP2004530661A (ja) 2001-03-14 2004-10-07 パラテック ファーマシューティカルズ インコーポレイテッド 抗真菌剤としての置換テトラサイクリン化合物
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
CA2444899C (en) 2001-04-24 2011-06-21 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
EP2311798A1 (en) 2002-01-08 2011-04-20 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
CN102531948A (zh) 2002-03-08 2012-07-04 帕拉特克药品公司 氨基-甲基取代的四环素类化合物
JP2005520846A (ja) 2002-03-21 2005-07-14 パラテック ファーマシューティカルズ インコーポレイテッド 置換されたテトラサイクリン化合物。
EA012136B1 (ru) 2002-07-12 2009-08-28 Пэрэтек Фамэсьютикэлс, Инк. Замещенные соединения тетрациклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта
JP2006503898A (ja) 2002-10-24 2006-02-02 パラテック ファーマシューティカルズ, インク. マラリア治療のための置換テトラサイクリン化合物
JP2006514119A (ja) * 2003-02-12 2006-04-27 アール アンド ピー コリア カンパニー リミテッド 溶解率が向上した難溶性薬剤の溶媒系
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
EP2319828A3 (en) 2003-07-09 2011-07-06 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
AU2004259661B2 (en) 2003-07-09 2011-11-10 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
JP5010284B2 (ja) * 2004-01-15 2012-08-29 パラテック ファーマシューティカルズ インコーポレイテッド テトラサイクリン化合物の芳香族a環誘導体
TWI261038B (en) * 2004-08-11 2006-09-01 Bo-Cheng Chen Bicycle gear-shifting handgrip
EP2284153A3 (en) 2004-10-25 2012-03-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
CA2585418A1 (en) * 2004-10-25 2006-05-04 Paratek Pharmaceuticals, Inc. 4-aminotetracyclines and methods of use thereof
AU2006210406C1 (en) * 2005-02-04 2013-03-07 Paratek Pharmaceuticals, Inc. 11a, 12-derivatives of tetracycline compounds
DE102005012595A1 (de) * 2005-03-18 2006-09-21 Lanxess Deutschland Gmbh Herstellung von Tri(chlorpropyl)phosphat
US20070093455A1 (en) * 2005-07-21 2007-04-26 Paul Abato 10-substituted tetracyclines and methods of use thereof
CA2622704A1 (en) * 2005-09-19 2007-03-29 Albemarle Corporation Highly concentrated pourable aqueous solutions of potassium ibuprofen their preparation and their uses
AU2007208214B2 (en) * 2006-01-24 2013-02-14 Paratek Pharmaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
EP2007713A2 (en) * 2006-04-17 2008-12-31 Teva Pharmaceutical Industries Ltd Isolation of tetracycline derivatives
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
DK2016045T3 (en) * 2006-04-24 2015-02-02 Teva Pharma TIGECYCLIN CRYSTAL FORM AND PROCEDURES FOR PREPARING IT
JP2009543544A (ja) * 2006-05-15 2009-12-10 パラテック ファーマシューティカルズ インコーポレイテッド 置換されたテトラサイクリン化合物を用いて、遺伝子または遺伝子産物の発現を調節する方法
WO2008045507A2 (en) 2006-10-11 2008-04-17 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of bacillus anthracis infections
TR201818983T4 (tr) 2006-12-21 2019-01-21 Paratek Pharm Innc İnflamatuvar Cilt Bozukluklarının Tedavisine Yönelik Olarak Sübstitüe Edilmiş Tetrasiklin Bileşikleri
SI2109602T1 (sl) 2006-12-21 2014-06-30 Paratek Pharmaceuticals, Inc. Derivati tetraciklina za zdravljenje bakterijskih, virusnih in parazitskih infekcij
EP2144614A1 (en) * 2007-04-12 2010-01-20 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
WO2008134048A2 (en) 2007-04-27 2008-11-06 Paratek Pharmaceuticals, Inc. Methods for synthesizing and purifying aminoalkyl tetracycline compounds
JP2010532759A (ja) 2007-07-06 2010-10-14 パラテック ファーマシューティカルズ インコーポレイテッド 置換テトラサイクリン化合物を合成するための方法
MX2010009693A (es) 2008-03-05 2010-12-20 Paratek Pharm Innc Compuestos de monociclina y metodos de uso de la misma.
PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
AU2009236631A1 (en) * 2008-04-14 2009-10-22 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
TW202436282A (zh) 2008-05-19 2024-09-16 美商Prtk Spv2公司 四環素化合物之甲苯磺酸鹽及同素異形體
US9629806B2 (en) * 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
CN102215681A (zh) * 2008-09-19 2011-10-12 帕拉特克药品公司 用于治疗类风湿性关节炎的四环素化合物和相关的治疗方法
US20120121706A1 (en) 2009-04-10 2012-05-17 Tufts Medical Center, Inc. PAR-1 Activation by Metalloproteinase-1 (MMP-1)
ES2739626T3 (es) 2011-05-12 2020-02-03 Paratek Pharm Innc Sales cristalinas de amida del ácido (4S,4aS,5aR,12aS)-4-dimetilamino-3,10,12,12a-tetrahidroxi-7-[(metoxi(metil)amino)-metil]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahidro-naftacen-2-carboxílico y métodos de uso de las mismas
MY200446A (en) 2016-11-01 2023-12-26 Paratek Pharm Innc 9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp)
MA49641A (fr) 2017-07-21 2021-06-02 Almirall Llc Traitement de lésions non inflammatoires

Also Published As

Publication number Publication date
SU510986A3 (ru) 1976-04-15
BE699091A (cg-RX-API-DMAC7.html) 1967-11-27
DE1617576C3 (de) 1980-12-11
NL6607516A (cg-RX-API-DMAC7.html) 1967-12-01
CH490087A (de) 1970-05-15
JPS5010373B1 (cg-RX-API-DMAC7.html) 1975-04-21
IL28009A (en) 1970-08-19
CS151454B2 (cg-RX-API-DMAC7.html) 1973-10-19
FI43622B (cg-RX-API-DMAC7.html) 1971-02-01
DE1617576A1 (de) 1972-04-27
US3557280A (en) 1971-01-19
AT272522B (de) 1969-07-10
LU53788A1 (cg-RX-API-DMAC7.html) 1967-07-31
NO126298B (cg-RX-API-DMAC7.html) 1973-01-22
DK117587B (da) 1970-05-11
GB1131007A (en) 1968-10-16
SE354417B (cg-RX-API-DMAC7.html) 1973-03-12
FR5953M (cg-RX-API-DMAC7.html) 1968-04-16
YU31326B (en) 1973-04-30
MY7100015A (en) 1971-12-31
GR33861B (el) 1968-02-09
DE1617576B2 (de) 1980-04-10
ES340956A1 (es) 1968-06-16

Similar Documents

Publication Publication Date Title
IT1140250B (it) Procedimento per la preparazione di soluzioni stabili di ossitetraciclina in acqua, adatte per somministrazioni per via parenterale ed orale
DK132030C (da) Stabiliseret vandigt enzympreparat
DK127700B (da) Elektrisk forbindelsesled med indstillelig kileforbindelse.
CH458654A (de) Verstellbarer Lehnstuhl
CH486864A (it) Seggiolone per bambini
IT7949430A0 (it) Derivati della noroscopolamina eprocedimento per la loro preparazione
IT1044808B (it) Derivati delonodrossi 4 oumarina e procedimenti per la loro preparazione
FR1516400A (fr) Charrue réversible
FR1531798A (fr) Siège réglable
IT1056720B (it) Benzensolfoniluree e metodo per la loro preparazione
FR1480511A (fr) Dispositif de raccordement notamment pour profilé tubulaire
DK120158B (da) Analogifremgangsmåde til fremstilling af i 11-stillingen substituerede 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-oner.
IL26042A (en) Substituted benzimidazoles,their preparation and use
ZA705448B (en) Dibenzazepine derivatives and their preparation
IL33788A0 (en) Pharmaceutically active thiachromone derivatives
FI42135C (fi) Laite parvekekaiteiden kiinnikkeissä
IL27674A (en) 1-sulphanilyl-2-imino-imidazolidine derivatives and their preparation
IL25527A (en) Indole derivatives and their preparation
IL27609A (en) Alpha-4-dimethylamino-and 4-phyrrolidinyl-1,2-diphenyl-3-methyl-2-cyclopropane-carbonyloxybutane and their preparation
IL27448A (en) 21-trialkylsiloxy derivatives of pregna-3,20-diones and their preparation
CH463455A (de) Konzentriertes, flüssiges Färbepräparat
BR6681913D0 (pt) Cadeira ajustavel e regulavel
ES332862A1 (es) Perfeccionamientos en recogedores de redes de pesca.
IT1033003B (it) Procedimento per la preparazione de soluzioni stabili di eteri eno loci steroidali perapeuticamente attivi
CA747588A (en) Water closets