GB1084467A - Improvements in or relating to steroids and the manufacture thereof - Google Patents
Improvements in or relating to steroids and the manufacture thereofInfo
- Publication number
- GB1084467A GB1084467A GB45980/64A GB4598064A GB1084467A GB 1084467 A GB1084467 A GB 1084467A GB 45980/64 A GB45980/64 A GB 45980/64A GB 4598064 A GB4598064 A GB 4598064A GB 1084467 A GB1084467 A GB 1084467A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- halo
- keto
- hydroxy
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003431 steroids Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical group O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910000091 aluminium hydride Inorganic materials 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000012320 chlorinating reagent Substances 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- -1 hydrocarbon carboxylic acid Chemical class 0.000 abstract 1
- 229960000890 hydrocortisone Drugs 0.000 abstract 1
- 230000033444 hydroxylation Effects 0.000 abstract 1
- 238000005805 hydroxylation reaction Methods 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 239000012280 lithium aluminium hydride Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000001451 organic peroxides Chemical class 0.000 abstract 1
- 229910000489 osmium tetroxide Inorganic materials 0.000 abstract 1
- 239000012285 osmium tetroxide Substances 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
-
- E—FIXED CONSTRUCTIONS
- E05—LOCKS; KEYS; WINDOW OR DOOR FITTINGS; SAFES
- E05B—LOCKS; ACCESSORIES THEREFOR; HANDCUFFS
- E05B3/00—Fastening knobs or handles to lock or latch parts
- E05B3/02—Fastening knobs or handles to the spindle by pinning or riveting
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US329272A US3305546A (en) | 1963-12-09 | 1963-12-09 | Process for the production of 16-halo-17(20)-pregnenes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1084467A true GB1084467A (en) | 1967-09-20 |
Family
ID=23284649
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB45980/64A Expired GB1084467A (en) | 1963-12-09 | 1964-11-11 | Improvements in or relating to steroids and the manufacture thereof |
| GB13534/67A Expired GB1084468A (en) | 1963-12-09 | 1964-11-11 | Improvements in or relating to steroids and the manufacture thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB13534/67A Expired GB1084468A (en) | 1963-12-09 | 1964-11-11 | Improvements in or relating to steroids and the manufacture thereof |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3305546A (enExample) |
| BE (1) | BE656870A (enExample) |
| DE (2) | DE1793599A1 (enExample) |
| FR (1) | FR1570405A (enExample) |
| GB (2) | GB1084467A (enExample) |
| IL (1) | IL22282A (enExample) |
| NL (3) | NL6414319A (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3364241A (en) * | 1966-07-29 | 1968-01-16 | Upjohn Co | Process for the production of 6alpha-fluoro-16alpha-halo pregnanes and the intermediates therefor |
| US3535348A (en) * | 1967-07-31 | 1970-10-20 | Upjohn Co | 3-oximes of 17(20)-en-21-oic acids of the pregnane series |
| US3539683A (en) * | 1967-07-31 | 1970-11-10 | Upjohn Co | Oral,parenteral and inhalation-therapy with 3,11-dioxo-4,17(20)-cis-pregnadien-21-oic acid,methyl ester,3-oxime |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB872032A (en) * | 1958-11-26 | 1961-07-05 | Upjohn Co | Improvements in or relating to steroids and the manufacture thereof |
| US3056808A (en) * | 1961-10-09 | 1962-10-02 | Upjohn Co | 15beta-fluorinated corticosteroids |
| US3158625A (en) * | 1963-06-17 | 1964-11-24 | Syntex Corp | 20-(lower aliphatic hydrocarbon)-delta17(20)-pregnen-21-oic acids |
-
0
- NL NL130311D patent/NL130311C/xx active
- BE BE656870D patent/BE656870A/xx unknown
-
1963
- 1963-12-09 US US329272A patent/US3305546A/en not_active Expired - Lifetime
-
1964
- 1964-10-19 IL IL22282A patent/IL22282A/xx unknown
- 1964-11-11 GB GB45980/64A patent/GB1084467A/en not_active Expired
- 1964-11-11 GB GB13534/67A patent/GB1084468A/en not_active Expired
- 1964-12-01 DE DE19641793599 patent/DE1793599A1/de active Pending
- 1964-12-01 DE DE19641493344 patent/DE1493344B1/de active Pending
- 1964-12-08 FR FR1570405D patent/FR1570405A/fr not_active Expired
- 1964-12-09 NL NL6414319A patent/NL6414319A/xx unknown
-
1969
- 1969-08-19 NL NL6912579A patent/NL6912579A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US3305546A (en) | 1967-02-21 |
| GB1084468A (en) | 1967-09-20 |
| DE1793599A1 (de) | 1972-02-03 |
| NL130311C (enExample) | |
| IL22282A (en) | 1968-03-28 |
| NL6912579A (enExample) | 1969-11-25 |
| FR1570405A (enExample) | 1969-06-13 |
| NL6414319A (enExample) | 1965-06-10 |
| DE1493344B1 (de) | 1970-07-09 |
| BE656870A (enExample) |
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