GB972953A - Steroids - Google Patents

Steroids

Info

Publication number
GB972953A
GB972953A GB751463A GB751463A GB972953A GB 972953 A GB972953 A GB 972953A GB 751463 A GB751463 A GB 751463A GB 751463 A GB751463 A GB 751463A GB 972953 A GB972953 A GB 972953A
Authority
GB
United Kingdom
Prior art keywords
steroid
yield
organic solvent
double bond
steroids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB751463A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA
Publication of GB972953A publication Critical patent/GB972953A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention comprises steroids having the formula <FORM:0972953/C1/1> wherein X is OH or Cl, R is (H)OAC when there is a double bond in the 5, 6-position and =O when there is a double bond in the 4, 5-position; and Ac is the radical of an aliphatic, cycloaliphatic, or aromatic carboxylic acid having 1-9 carbon atoms and a process for the preparation thereof by treating the corresponding 21-methylene-steroid with diethanolamine in an organic solvent so as to yield the corresponding 21-diethanolaminomethyl-steroid, which is chlorinated where appropriate, so as to yield the corresponding 21-(bis-(b -chloroethyl)]-amino-methyl steroid. As organic solvent there may be used tertiary butyl alcohol, and as chlorinating agent there may be used mesyl chloride.
GB751463A 1962-02-28 1963-02-25 Steroids Expired GB972953A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT401762 1962-02-28

Publications (1)

Publication Number Publication Date
GB972953A true GB972953A (en) 1964-10-21

Family

ID=11112031

Family Applications (1)

Application Number Title Priority Date Filing Date
GB751463A Expired GB972953A (en) 1962-02-28 1963-02-25 Steroids

Country Status (1)

Country Link
GB (1) GB972953A (en)

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