|
MX354217B
(es)
|
2010-05-14 |
2018-02-19 |
Dana Farber Cancer Inst Inc |
Composiciones y metodos para el tratamiento de leucemia.
|
|
CA2799381A1
(en)
|
2010-05-14 |
2011-11-17 |
Dana-Farber Cancer Institute, Inc. |
Male contraceptive compositions and methods of use
|
|
MX362384B
(es)
|
2010-05-14 |
2019-01-15 |
Dana Farber Cancer Inst Inc |
Composiciones y metodos para tratar neoplasias, enfermedades inflamatorias y otros trastornos.
|
|
AR084070A1
(es)
|
2010-12-02 |
2013-04-17 |
Constellation Pharmaceuticals Inc |
Inhibidores del bromodominio y usos de los mismos
|
|
WO2012075456A1
(en)
|
2010-12-02 |
2012-06-07 |
Constellation Pharmaceuticals |
Bromodomain inhibitors and uses thereof
|
|
EP2705039B1
(en)
|
2011-05-04 |
2017-07-26 |
Constellation Pharmaceuticals, Inc. |
Bromodomain inhibitors and uses thereof
|
|
WO2012174487A2
(en)
|
2011-06-17 |
2012-12-20 |
Constellation Pharmaceuticals, Inc. |
Bromodomain inhibitors and uses thereof
|
|
WO2013027168A1
(en)
|
2011-08-22 |
2013-02-28 |
Pfizer Inc. |
Novel heterocyclic compounds as bromodomain inhibitors
|
|
WO2013033270A2
(en)
*
|
2011-08-29 |
2013-03-07 |
Coferon, Inc. |
Bromodomain ligands capable of dimerizing in an aqueous solution, and methods of using same
|
|
WO2013033269A1
(en)
*
|
2011-08-29 |
2013-03-07 |
Coferon, Inc. |
Bioorthogonal monomers capable of dimerizing and targeting bromodomains and methods of using same
|
|
DE102011082013A1
(de)
|
2011-09-01 |
2013-03-07 |
Bayer Pharma AG |
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
|
|
WO2013097052A1
(en)
|
2011-12-30 |
2013-07-04 |
Abbott Laboratories |
Bromodomain inhibitors
|
|
CN104334526A
(zh)
|
2012-04-20 |
2015-02-04 |
艾伯维公司 |
异吲哚酮衍生物
|
|
TWI602820B
(zh)
*
|
2012-06-06 |
2017-10-21 |
星宿藥物公司 |
溴域抑制劑及其用途
|
|
EP2864336B1
(en)
|
2012-06-06 |
2016-11-23 |
Constellation Pharmaceuticals, Inc. |
Benzo[b]isoxazoloazepine bromodomain inhibitors and uses thereof
|
|
RU2632915C2
(ru)
|
2012-06-12 |
2017-10-11 |
Эббви Инк. |
Производные пиридинона и пиридазинона
|
|
EP2861255B1
(en)
|
2012-06-19 |
2019-10-09 |
The Broad Institute, Inc. |
Diagnostic and treatment methods in subjects having or at risk of developing resistance to cancer therapy
|
|
KR20150041787A
(ko)
|
2012-08-16 |
2015-04-17 |
바이엘 파마 악티엔게젤샤프트 |
2,3-벤조디아제핀
|
|
JP6276277B2
(ja)
|
2012-09-28 |
2018-02-07 |
バイエル ファーマ アクチエンゲゼルシャフト |
Betタンパク質阻害性の5−アリールトリアゾロアゼピン
|
|
EP2970312B1
(en)
|
2013-03-11 |
2017-11-15 |
The Regents of The University of Michigan |
Bet bromodomain inhibitors and therapeutic methods using the same
|
|
US10035800B2
(en)
*
|
2013-03-12 |
2018-07-31 |
Abbvie Inc. |
Substituted 1,4,10-triazadibenzo[cd,f]azulenes, substituted 1,4,5,10-tetraazadibenzo[cd,f]azulenes and substituted 1,4,5,7,10-pentaazadibenzo[cd,f]azulenes as bromodomain inhibitors
|
|
WO2014159392A1
(en)
|
2013-03-14 |
2014-10-02 |
Dana-Farber Cancer Institute, Inc. |
Bromodomain binding reagents and uses thereof
|
|
BR112015022417A2
(pt)
|
2013-03-14 |
2017-07-18 |
Convergene Llc |
métodos e composições para inibição de proteínas contendo bromodomínio
|
|
CA2903881C
(en)
|
2013-03-15 |
2021-05-18 |
Incyte Corporation |
Tricyclic heterocycles as bet protein inhibitors
|
|
EA027139B1
(ru)
|
2013-04-26 |
2017-06-30 |
Бейджин, Лтд. |
Замещенные 5-(3,5-диметилизоксазол-4-ил)индолин-2-оны
|
|
EP3019502B1
(en)
|
2013-07-08 |
2017-05-17 |
Incyte Holdings Corporation |
Tricyclic heterocycles as bet protein inhibitors
|
|
KR20160034379A
(ko)
|
2013-07-25 |
2016-03-29 |
다나-파버 캔서 인스티튜트 인크. |
전사 인자의 억제제 및 그의 용도
|
|
WO2015070020A2
(en)
|
2013-11-08 |
2015-05-14 |
Dana-Farber Cancer Institute, Inc. |
Combination therapy for cancer using bromodomain and extra-terminal (bet) protein inhibitors
|
|
WO2015081203A1
(en)
|
2013-11-26 |
2015-06-04 |
Incyte Corporation |
Bicyclic heterocycles as bet protein inhibitors
|
|
US9315501B2
(en)
|
2013-11-26 |
2016-04-19 |
Incyte Corporation |
Bicyclic heterocycles as BET protein inhibitors
|
|
US9309246B2
(en)
|
2013-12-19 |
2016-04-12 |
Incyte Corporation |
Tricyclic heterocycles as BET protein inhibitors
|
|
EP3099696A4
(en)
|
2014-01-31 |
2017-07-05 |
Dana-Farber Cancer Institute, Inc. |
Diazepane derivatives and uses thereof
|
|
WO2015117087A1
(en)
|
2014-01-31 |
2015-08-06 |
Dana-Farber Cancer Institute, Inc. |
Uses of diazepane derivatives
|
|
RU2016134947A
(ru)
|
2014-01-31 |
2018-03-01 |
Дана-Фарбер Кансер Институт, Инк. |
Производные диаминопиримидин бензолсульфона и их применение
|
|
AU2015222887B2
(en)
|
2014-02-28 |
2019-06-27 |
The Regents Of The University Of Michigan |
9H-pyrimido[4,5-b]indoles and related analogs as BET bromodomain inhibitors
|
|
AU2015222805B2
(en)
*
|
2014-02-28 |
2020-05-21 |
Tensha Therapeutics, Inc. |
Treatment of conditions associated with hyperinsulinaemia
|
|
WO2015156601A1
(en)
*
|
2014-04-09 |
2015-10-15 |
Kainos Medicine, Inc. |
Bromodomain-inhibiting compounds and pharmaceutical composition comprising same for preventing or treating a cancer
|
|
WO2015164480A1
(en)
|
2014-04-23 |
2015-10-29 |
Incyte Corporation |
1H-PYRROLO[2,3-c]PYRIDIN-7(6H)-ONES AND PYRAZOLO[3,4-c]PYRIDIN-7(6H)-ONES AS INHIBITORS OF BET PROTEINS
|
|
CA2952830C
(en)
|
2014-06-20 |
2022-11-01 |
Constellation Pharmaceuticals, Inc. |
Crystalline forms of 2-((4s)-6-(4-chlorophenyl)-1-methyl-4h-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide
|
|
EP3177626A4
(en)
|
2014-08-08 |
2017-12-27 |
Dana Farber Cancer Institute, Inc. |
Diazepane derivatives and uses thereof
|
|
BR112017002190A2
(pt)
|
2014-08-08 |
2017-11-21 |
Dana Farber Cancer Inst Inc |
derivados de di-hidropteridinona e usos dos mesmos
|
|
US9527864B2
(en)
|
2014-09-15 |
2016-12-27 |
Incyte Corporation |
Tricyclic heterocycles as BET protein inhibitors
|
|
EP3262045A1
(en)
|
2015-02-27 |
2018-01-03 |
The Regents of The University of Michigan |
9h-pyrimido [4,5-b]indoles as bet bromodomain inhibitors
|
|
GB201504694D0
(en)
|
2015-03-19 |
2015-05-06 |
Glaxosmithkline Ip Dev Ltd |
Covalent conjugates
|
|
WO2016196065A1
(en)
|
2015-05-29 |
2016-12-08 |
Genentech, Inc. |
Methods and compositions for assessing responsiveness of cancers to bet inhibitors
|
|
AU2016276963C1
(en)
|
2015-06-12 |
2021-08-05 |
Dana-Farber Cancer Institute, Inc. |
Combination therapy of transcription inhibitors and kinase inhibitors
|
|
WO2016203335A1
(en)
|
2015-06-18 |
2016-12-22 |
Pfizer Inc. |
Novel pyrido[2,3-b]pyrazinones as bet-family bromodomain inhibitors
|
|
JP2018520124A
(ja)
|
2015-06-26 |
2018-07-26 |
テンシャ セラピューティクス,インコーポレイテッド |
Nut正中線癌の治療
|
|
EP3334725B1
(en)
|
2015-08-10 |
2025-04-23 |
Dana-Farber Cancer Institute, Inc. |
Bromodomain and extra terminal (bet) inhibitor and a protein phosphatase 2a (pp2a) activator for treating bet inhibitor resistant cancer
|
|
WO2017037567A1
(en)
*
|
2015-09-03 |
2017-03-09 |
Pfizer Inc. |
Regulators of frataxin
|
|
US10881668B2
(en)
|
2015-09-11 |
2021-01-05 |
Dana-Farber Cancer Institute, Inc. |
Acetamide thienotriazolodiazepines and uses thereof
|
|
CN108472300A
(zh)
|
2015-09-11 |
2018-08-31 |
达纳-法伯癌症研究所股份有限公司 |
氰基噻吩并三唑并二氮杂环庚三烯及其用途
|
|
TW201722966A
(zh)
|
2015-10-29 |
2017-07-01 |
英塞特公司 |
Bet蛋白質抑制劑之非晶固體形式
|
|
MX2018006499A
(es)
|
2015-11-25 |
2018-08-01 |
Dana Farber Cancer Inst Inc |
Inhibidores de bromodominio bivalentes y usos de los mismos.
|
|
JP2019500336A
(ja)
|
2015-12-03 |
2019-01-10 |
バイエル・クロップサイエンス・アクチェンゲゼルシャフト |
殺虫剤としてのメソイオン性ハロゲン化3−(アセチル)−1−[(1,3−チアゾール−5−イル)メチル]−1H−イミダゾ[1,2−a]ピリジン−4−イウム−2−オレート誘導体及び関連する化合物
|
|
WO2017142881A1
(en)
|
2016-02-15 |
2017-08-24 |
The Regents Of The University Of Michigan |
Fused 1,4-oxazepines and related analogs as bet bromodomain inhibitors
|
|
CA3020281A1
(en)
|
2016-04-06 |
2017-10-12 |
The Regents Of The University Of Michigan |
Monofunctional intermediates for ligand-dependent target protein degradation
|
|
JP7037500B2
(ja)
|
2016-04-06 |
2022-03-16 |
ザ リージェンツ オブ ザ ユニヴァシティ オブ ミシガン |
Mdm2タンパク質分解剤
|
|
UA123168C2
(uk)
|
2016-04-12 |
2021-02-24 |
Дзе Ріджентс Оф Дзе Юніверсіті Оф Мічіган |
Деструктори білка вет
|
|
ES2793239T3
(es)
|
2016-04-15 |
2020-11-13 |
Abbvie Inc |
Inhibidores del bromodominio
|
|
SMT202300155T1
(it)
|
2016-06-20 |
2023-07-20 |
Incyte Corp |
Forme solide cristalline di un inibitore di bet
|
|
US10918647B2
(en)
|
2016-07-26 |
2021-02-16 |
University Of Southern California |
Selective bromodomain inhibition of fungal Bdf1
|
|
JP7035027B2
(ja)
|
2016-09-13 |
2022-03-14 |
ザ リージェンツ オブ ザ ユニヴァシティ オブ ミシガン |
Betタンパク質分解物質としての縮合1,4-ジアゼピン
|
|
CN110062759B
(zh)
|
2016-09-13 |
2022-05-24 |
密执安大学评议会 |
作为bet蛋白降解剂的稠合的1,4-氧氮杂䓬
|
|
EP3577120A1
(en)
|
2017-02-03 |
2019-12-11 |
The Regents of The University of Michigan |
Fused 1,4-diazepines as bet bromodomain inhibitors
|
|
CN108727380A
(zh)
*
|
2017-04-13 |
2018-11-02 |
中国科学院上海药物研究所 |
一种brd4抑制剂及其制备和应用
|
|
US20210179620A1
(en)
|
2017-06-16 |
2021-06-17 |
Basf Se |
Mesoionic imidazolium compounds and derivatives for combating animal pests
|
|
US11267822B2
(en)
|
2017-09-13 |
2022-03-08 |
The Regents Of The University Of Michigan |
BET bromodomain protein degraders with cleavable linkers
|
|
CN112867705B
(zh)
|
2018-04-04 |
2024-08-20 |
埃皮欧黛公司 |
阿片样物质受体调节剂以及与其相关的产品和方法
|
|
WO2021175432A1
(en)
|
2020-03-04 |
2021-09-10 |
Boehringer Ingelheim International Gmbh |
Method for administration of an anti cancer agent
|
|
US11833155B2
(en)
|
2020-06-03 |
2023-12-05 |
Incyte Corporation |
Combination therapy for treatment of myeloproliferative neoplasms
|
|
JP2023532233A
(ja)
|
2020-06-23 |
2023-07-27 |
ジェネンテック, インコーポレイテッド |
大環状化合物及びその使用方法
|
|
TW202304869A
(zh)
|
2021-04-05 |
2023-02-01 |
美商艾碧奧戴股份有限公司 |
類鴉片受體調節劑
|
|
US20240316061A1
(en)
|
2021-09-17 |
2024-09-26 |
Institut Curie |
Bet inhibitors for treating pab1 deficient cancer
|
|
WO2023205251A1
(en)
|
2022-04-19 |
2023-10-26 |
Nuevolution A/S |
Compounds active towards bromodomains
|