GB0818033D0 - Novel compound - Google Patents

Novel compound

Info

Publication number
GB0818033D0
GB0818033D0 GBGB0818033.3A GB0818033A GB0818033D0 GB 0818033 D0 GB0818033 D0 GB 0818033D0 GB 0818033 A GB0818033 A GB 0818033A GB 0818033 D0 GB0818033 D0 GB 0818033D0
Authority
GB
United Kingdom
Prior art keywords
novel compound
novel
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0818033.3A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Respivert Ltd
Original Assignee
Respivert Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40019929&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB0818033(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Respivert Ltd filed Critical Respivert Ltd
Priority to GBGB0818033.3A priority Critical patent/GB0818033D0/en
Publication of GB0818033D0 publication Critical patent/GB0818033D0/en
Priority to US13/121,999 priority patent/US8293748B2/en
Priority to DK09736271.9T priority patent/DK2350047T3/da
Priority to BRPI0920840-2A priority patent/BRPI0920840B1/pt
Priority to CN2009801395551A priority patent/CN102256964A/zh
Priority to AU2009299555A priority patent/AU2009299555B2/en
Priority to EP09785724.7A priority patent/EP2350049B1/en
Priority to PCT/GB2009/051304 priority patent/WO2010038086A2/en
Priority to NZ591426A priority patent/NZ591426A/xx
Priority to EA201170520A priority patent/EA019590B1/ru
Priority to CA2738828A priority patent/CA2738828A1/en
Priority to MX2011003553A priority patent/MX2011003553A/es
Priority to CN200980139617.9A priority patent/CN102203078B/zh
Priority to HRP20130895AT priority patent/HRP20130895T1/hr
Priority to MYPI2011001435A priority patent/MY159230A/en
Priority to PT97362719T priority patent/PT2350047E/pt
Priority to RS20130407A priority patent/RS52979B/sr
Priority to MX2011003552A priority patent/MX2011003552A/es
Priority to KR1020117009956A priority patent/KR101660266B1/ko
Priority to ES09785724.7T priority patent/ES2461496T3/es
Priority to JP2011529636A priority patent/JP5571088B2/ja
Priority to PCT/GB2009/051303 priority patent/WO2010038085A2/en
Priority to US13/121,445 priority patent/US8293771B2/en
Priority to ES09736271T priority patent/ES2428917T3/es
Priority to EA201170521A priority patent/EA020641B1/ru
Priority to KR1020117009977A priority patent/KR20110070887A/ko
Priority to SI200930725T priority patent/SI2350047T1/sl
Priority to CA2738827A priority patent/CA2738827C/en
Priority to JP2011529637A priority patent/JP2012504591A/ja
Priority to UAA201103555A priority patent/UA105014C2/uk
Priority to MYPI20111436 priority patent/MY150611A/en
Priority to EP09736271.9A priority patent/EP2350047B1/en
Priority to PE2011000798A priority patent/PE20110810A1/es
Priority to AU2009299554A priority patent/AU2009299554B8/en
Priority to UAA201103554A priority patent/UA104731C2/ru
Priority to BRPI0920707A priority patent/BRPI0920707A2/pt
Priority to HK12100606.2A priority patent/HK1160129B/en
Priority to MEP-2013-108A priority patent/ME01604B/me
Priority to PE2011000797A priority patent/PE20110598A1/es
Priority to HK11112365.9A priority patent/HK1157781B/en
Priority to PL09736271T priority patent/PL2350047T3/pl
Priority to NZ591427A priority patent/NZ591427A/xx
Priority to CO11037006A priority patent/CO6351785A2/es
Priority to CO11037018A priority patent/CO6351786A2/es
Priority to CL2011000735A priority patent/CL2011000735A1/es
Priority to HN2011000874A priority patent/HN2011000874A/es
Priority to NI201100062A priority patent/NI201100062A/es
Priority to EC2011010948A priority patent/ECSP11010948A/es
Priority to NI201100063A priority patent/NI201100063A/es
Priority to EC2011010949A priority patent/ECSP11010949A/es
Priority to CL2011000737A priority patent/CL2011000737A1/es
Priority to HN2011000876A priority patent/HN2011000876A/es
Priority to ZA2011/03181A priority patent/ZA201103181B/en
Priority to ZA2011/03180A priority patent/ZA201103180B/en
Priority to CR20110230A priority patent/CR20110230A/es
Priority to CR20110477A priority patent/CR20110477A/es
Priority to US13/616,696 priority patent/US8618140B2/en
Priority to SM201300097T priority patent/SMT201300097B/xx
Priority to CY20131100835T priority patent/CY1114665T1/el
Priority to US14/139,982 priority patent/US8975285B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
GBGB0818033.3A 2008-10-02 2008-10-02 Novel compound Ceased GB0818033D0 (en)

Priority Applications (60)

Application Number Priority Date Filing Date Title
GBGB0818033.3A GB0818033D0 (en) 2008-10-02 2008-10-02 Novel compound
US13/121,999 US8293748B2 (en) 2008-10-02 2009-10-02 p38 MAP kinase inhibitors
DK09736271.9T DK2350047T3 (da) 2008-10-02 2009-10-02 p38-MAP-KINASEINHIBITORER
BRPI0920840-2A BRPI0920840B1 (pt) 2008-10-02 2009-10-02 Inibidor de quinase mapk p38
CN2009801395551A CN102256964A (zh) 2008-10-02 2009-10-02 p38MAP激酶抑制剂
AU2009299555A AU2009299555B2 (en) 2008-10-02 2009-10-02 p38 map kinase inhibitors
EP09785724.7A EP2350049B1 (en) 2008-10-02 2009-10-02 P38 map kinase inhibitors
PCT/GB2009/051304 WO2010038086A2 (en) 2008-10-02 2009-10-02 Novel compounds
NZ591426A NZ591426A (en) 2008-10-02 2009-10-02 P38 map kinase inhibitors
EA201170520A EA019590B1 (ru) 2008-10-02 2009-10-02 ИНГИБИТОР p38 MAPK-КИНАЗЫ
CA2738828A CA2738828A1 (en) 2008-10-02 2009-10-02 P38 map kinase inhibitors
MX2011003553A MX2011003553A (es) 2008-10-02 2009-10-02 Inhibidores de las enzimas de proteina cinasa activadas por mitogeno p38.
CN200980139617.9A CN102203078B (zh) 2008-10-02 2009-10-02 p38MAP激酶抑制剂
HRP20130895AT HRP20130895T1 (en) 2008-10-02 2009-10-02 P38 map kinase inhibitors
MYPI2011001435A MY159230A (en) 2008-10-02 2009-10-02 P38 map kinase inhibitors
PT97362719T PT2350047E (pt) 2008-10-02 2009-10-02 Inibidor de p38 mapk quinase
RS20130407A RS52979B (sr) 2008-10-02 2009-10-02 Inhibitori p38 map kinaze
MX2011003552A MX2011003552A (es) 2008-10-02 2009-10-02 Inhibidores de las enzimas de proteina cinasa activadas por mitogeno p38.
KR1020117009956A KR101660266B1 (ko) 2008-10-02 2009-10-02 Ｐ38 엠에이피 키나제 억제제
ES09785724.7T ES2461496T3 (es) 2008-10-02 2009-10-02 Inhibidores de cinasa MAP p38
JP2011529636A JP5571088B2 (ja) 2008-10-02 2009-10-02 ｐ３８ＭＡＰキナーゼ阻害剤
PCT/GB2009/051303 WO2010038085A2 (en) 2008-10-02 2009-10-02 P38 mapk kinase inhibitor
US13/121,445 US8293771B2 (en) 2008-10-02 2009-10-02 p38 MAP kinase inhibitors
ES09736271T ES2428917T3 (es) 2008-10-02 2009-10-02 Inhibidores de p38 MAP cinasa
EA201170521A EA020641B1 (ru) 2008-10-02 2009-10-02 Производные n-(1-фенил-3-алкилпиразол-5-ил)-n'-арилмочевины
KR1020117009977A KR20110070887A (ko) 2008-10-02 2009-10-02 Ｐ38 엠에이피 키나제 억제제
SI200930725T SI2350047T1 (sl) 2008-10-02 2009-10-02 Inhibitorji P38 MAP kinaze
CA2738827A CA2738827C (en) 2008-10-02 2009-10-02 P38 map kinase inhibitors
JP2011529637A JP2012504591A (ja) 2008-10-02 2009-10-02 ｐ３８ＭＡＰキナーゼ阻害剤
UAA201103555A UA105014C2 (uk) 2008-10-02 2009-10-02 Інгібітор p38 map-кінази
MYPI20111436 MY150611A (en) 2008-10-02 2009-10-02 P38 map kinase inhibitors
EP09736271.9A EP2350047B1 (en) 2008-10-02 2009-10-02 P38 map kinase inhibitors
PE2011000798A PE20110810A1 (es) 2008-10-02 2009-10-02 Inhibidores de las enzimas de proteina cinasa activadas por mitogeno p38
AU2009299554A AU2009299554B8 (en) 2008-10-02 2009-10-02 P38 MAP kinase inhibitors
UAA201103554A UA104731C2 (ru) 2008-10-02 2009-10-02 Ингибиторы р38 мар-киназ
BRPI0920707A BRPI0920707A2 (pt) 2008-10-02 2009-10-02 compostos
HK12100606.2A HK1160129B (en) 2008-10-02 2009-10-02 P38 map kinase inhibitors
MEP-2013-108A ME01604B (me) 2008-10-02 2009-10-02 Inhibitori p38 map kinaze
PE2011000797A PE20110598A1 (es) 2008-10-02 2009-10-02 Inhibidores de las enzimas de proteina cinasa activadas por mitogeno p38
HK11112365.9A HK1157781B (en) 2008-10-02 2009-10-02 P38 map kinase inhibitors
PL09736271T PL2350047T3 (pl) 2008-10-02 2009-10-02 Inhibitory kinazy MAP P38
NZ591427A NZ591427A (en) 2008-10-02 2009-10-02 P38 map kinase inhibitors
CO11037006A CO6351785A2 (es) 2008-10-02 2011-03-25 Inhibidores de cinasa map p39
CO11037018A CO6351786A2 (es) 2008-10-02 2011-03-25 Inkibidores de la cinasa map p38
CL2011000735A CL2011000735A1 (es) 2008-10-02 2011-04-01 N-[4-({4-[3-(3-terc-butil-1-p-tolil-1h-pirazol-5-il)ureido]naftalen-1-il-oxi}metil)piridin-2-il]-2-metoxiacetamida; procedimiento de preparacion; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de epoc, asma, dermatitis de contacto, artritis, entre otros.
HN2011000874A HN2011000874A (es) 2008-10-02 2011-04-01 Inhibidores de las enzimas de proteina cinasa activadas por mitogeno p38
NI201100062A NI201100062A (es) 2008-10-02 2011-04-01 Inhibidores de las enzimas de proteína cinasa activadas por mitógeno p38.
EC2011010948A ECSP11010948A (es) 2008-10-02 2011-04-01 Inhibidores de las enzimas de proteína cinasa activadas por
NI201100063A NI201100063A (es) 2008-10-02 2011-04-01 Inhibidores de las enzimas de proteína cinasa activadas por mitógeno p38.
EC2011010949A ECSP11010949A (es) 2008-10-02 2011-04-01 Inhibidores de las enzimas de proteína cinasa activadas por mitógeno p38
CL2011000737A CL2011000737A1 (es) 2008-10-02 2011-04-01 Compuestos derivados de fenil/naftil-3-(1-fenil-1h-pirazol-5-il)urea, inhibidores de mapk p38 y de baja toxicidad; composicion farmaceutica; y su uso para el tratamiento de epoc, asma, fibrosis quistica, dermatitis de contacto, colitis ulcerosa, artritis reumatoide, carcinoma de mama, entre otros.
HN2011000876A HN2011000876A (es) 2008-10-02 2011-04-01 Inhibidores de las enzimas de proteina cinaza activadas por mitogeno p38
ZA2011/03181A ZA201103181B (en) 2008-10-02 2011-04-29 P38 map kinase inhibitors
ZA2011/03180A ZA201103180B (en) 2008-10-02 2011-04-29 P38 map kinase inhibitors
CR20110230A CR20110230A (es) 2008-10-02 2011-05-02 Inhibidores de las enzimas de proteina cinasa activadas por mitogeno p38
CR20110477A CR20110477A (es) 2008-10-02 2011-09-06 Inhibidores de enzimas de proteina cinasa activadas por mitogeno p38
US13/616,696 US8618140B2 (en) 2008-10-02 2012-09-14 P38 MAP kinase inhibitors
SM201300097T SMT201300097B (it) 2008-10-02 2013-09-05 Inibitori delle chinasi map p38
CY20131100835T CY1114665T1 (el) 2008-10-02 2013-09-25 Αναστολεις p38 map κινασης
US14/139,982 US8975285B2 (en) 2008-10-02 2013-12-24 P38 MAP kinase inhibitors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0818033.3A GB0818033D0 (en) 2008-10-02 2008-10-02 Novel compound

Publications (1)

Publication Number Publication Date
GB0818033D0 true GB0818033D0 (en) 2008-11-05

Family

ID=40019929

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0818033.3A Ceased GB0818033D0 (en) 2008-10-02 2008-10-02 Novel compound

Country Status (32)

Country Link
US (1) US8293771B2 (enExample)
EP (1) EP2350047B1 (enExample)
JP (1) JP5571088B2 (enExample)
KR (1) KR101660266B1 (enExample)
CN (1) CN102203078B (enExample)
AU (1) AU2009299554B8 (enExample)
CA (1) CA2738827C (enExample)
CL (1) CL2011000735A1 (enExample)
CO (1) CO6351785A2 (enExample)
CR (1) CR20110230A (enExample)
CY (1) CY1114665T1 (enExample)
DK (1) DK2350047T3 (enExample)
EA (1) EA019590B1 (enExample)
EC (1) ECSP11010948A (enExample)
ES (1) ES2428917T3 (enExample)
GB (1) GB0818033D0 (enExample)
HN (1) HN2011000874A (enExample)
HR (1) HRP20130895T1 (enExample)
ME (1) ME01604B (enExample)
MX (1) MX2011003552A (enExample)
MY (1) MY150611A (enExample)
NI (1) NI201100062A (enExample)
NZ (1) NZ591426A (enExample)
PE (1) PE20110810A1 (enExample)
PL (1) PL2350047T3 (enExample)
PT (1) PT2350047E (enExample)
RS (1) RS52979B (enExample)
SI (1) SI2350047T1 (enExample)
SM (1) SMT201300097B (enExample)
UA (2) UA104731C2 (enExample)
WO (1) WO2010038085A2 (enExample)
ZA (1) ZA201103181B (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5511680B2 (ja) 2007-12-19 2014-06-04 キャンサー・リサーチ・テクノロジー・リミテッド ピリド［２，３−ｂ］ピラジン−８−置換化合物及びその使用
PE20110598A1 (es) * 2008-10-02 2011-08-31 Respivert Ltd Inhibidores de las enzimas de proteina cinasa activadas por mitogeno p38
MX2011006220A (es) 2008-12-11 2011-06-28 Respivert Ltd Inhibidores de la proteina cinasa activada por el mitogeno p38.
GB0905955D0 (en) 2009-04-06 2009-05-20 Respivert Ltd Novel compounds
EP2236505A1 (de) * 2009-04-03 2010-10-06 Bayer CropScience AG Acylierte Aminopyridine und - pyridazine als Insektizide
GB0921730D0 (en) * 2009-12-11 2010-01-27 Respivert Ltd Method of treatment
NZ601085A (en) 2010-02-01 2015-04-24 Cancer Rec Tech Ltd 1-(5-tert-butyl-2-phenyl-2h-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1h-imidazo[4,5-b]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapy
GB201005589D0 (en) 2010-04-01 2010-05-19 Respivert Ltd Novel compounds
JP5787977B2 (ja) 2010-04-08 2015-09-30 レスピバート・リミテツド Ｐ３８ｍａｐキナーゼ阻害剤
US9260410B2 (en) 2010-04-08 2016-02-16 Respivert Ltd. P38 MAP kinase inhibitors
WO2011158044A2 (en) * 2010-06-17 2011-12-22 Respivert Limited Respiratory formulations and compounds for use therein
GB201010193D0 (en) * 2010-06-17 2010-07-21 Respivert Ltd Medicinal use
GB201010196D0 (en) * 2010-06-17 2010-07-21 Respivert Ltd Methods
EP2578582A1 (en) 2011-10-03 2013-04-10 Respivert Limited 1-Pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl)ureas as p38 MAP kinase inhibitors
EP2763984B1 (en) 2011-10-03 2016-04-20 Respivert Limited 1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl)ureas as p38 map kinase inhibitors
EP2788345B1 (en) * 2011-12-09 2020-06-10 Chiesi Farmaceutici S.p.A. Derivatives of 4-hydroxy-1,2,3,4-tetrahydronaphtalen-1-yl urea and their use in the treatment of, inter alia, diseases of the respiratory tract
GB201214750D0 (en) 2012-08-17 2012-10-03 Respivert Ltd Compounds
EP2890701B1 (en) 2012-08-29 2017-03-29 Respivert Limited Kinase inhibitors
WO2014033447A2 (en) 2012-08-29 2014-03-06 Respivert Limited Kinase inhibitors
US20150210722A1 (en) 2012-08-29 2015-07-30 Respivert Limited Kinase inhibitors
GB201215357D0 (en) 2012-08-29 2012-10-10 Respivert Ltd Compounds
WO2014076484A1 (en) 2012-11-16 2014-05-22 Respivert Limited Kinase inhibitors
US20160016934A1 (en) 2013-03-14 2016-01-21 Respivert Limited Kinase inhibitors
US9771353B2 (en) 2013-04-02 2017-09-26 Topivert Pharma Limited Kinase inhibitors based upon N-alkyl pyrazoles
BR112015024678B1 (pt) 2013-04-02 2023-02-23 Oxular Acquisitions Limited Composto inibidor da cinase, formulação farmacêutica que compreende o mesmo, seus usos, processo para sua preparação e intermediários
GB201320732D0 (en) 2013-11-25 2014-01-08 Cancer Rec Tech Ltd Methods of chemical synthesis
GB201320729D0 (en) 2013-11-25 2014-01-08 Cancer Rec Tech Ltd Therapeutic compounds and their use
JP6514703B2 (ja) 2013-12-20 2019-05-15 トピバート ファーマ リミテッド キナーゼインヒビターとして有用な尿素誘導体
TWI664967B (zh) 2014-02-14 2019-07-11 英商瑞斯比維特有限公司 新穎化合物（一）
MA40775A (fr) 2014-10-01 2017-08-08 Respivert Ltd Dérivé d'acide 4-(4-(4-phényluréido-naphtalén -1-yl) oxy-pyridin-2-yl) amino-benzoïque utilisé en tant qu'inhibiteur de la kinase p38
CA3015978A1 (en) 2016-04-06 2017-10-12 Topivert Pharma Limited Kinase inhibitors
GB201611712D0 (en) * 2016-07-02 2016-08-17 Hvivo Services Ltd Methods and compounds for the treatment or prevention of severe or persistent influenza
GB201721793D0 (en) 2017-12-22 2018-02-07 Hvivo Services Ltd Methods and compunds for the treatment or prevention of hypercytokinemia and severe influenza
EP4219489A3 (en) 2018-05-30 2023-11-15 Washington University Mitogen-activated protein kinase inhibitors, methods of making, and methods of use thereof
KR102789258B1 (ko) * 2022-10-26 2025-04-01 (의료)길의료재단 신규화합물 및 이를 유효성분으로 포함하는 폐섬유화증 예방 또는 치료용 약학 조성물

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001521934A (ja) 1997-11-03 2001-11-13 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド 抗炎症薬としての芳香族ヘテロ環式化合物
US7329670B1 (en) 1997-12-22 2008-02-12 Bayer Pharmaceuticals Corporation Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
RU2265597C2 (ru) 1997-12-22 2005-12-10 Байер Копэрейшн Арил- и гетероарилзамещенные гетероциклические производные мочевины, способ ингибирования киназы raf и фармацевтическая композиция
DK1043995T3 (da) 1997-12-22 2007-03-05 Bayer Pharmaceuticals Corp Inhibering af p38 kinaseaktivitet ved anvendelse af aryl- og heteroaryl-substituerede, heterocykliske urinstoffer
CA2315720A1 (en) 1997-12-22 1999-07-01 Bayer Corporation Inhibition of p38 kinase activity using substituted heterocyclic ureas
US20080300281A1 (en) 1997-12-22 2008-12-04 Jacques Dumas Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas
JP2002506873A (ja) 1998-03-18 2002-03-05 アリアド・ファーマシューティカルズ・インコーポレイテッド 複素環式シグナル伝達阻害剤、それを含む組成物
UA73492C2 (en) 1999-01-19 2005-08-15 Aromatic heterocyclic compounds as antiinflammatory agents
EP1200411B1 (en) 1999-07-09 2005-12-14 Boehringer Ingelheim Pharmaceuticals Inc. Process for synthesis of heteroaryl-substituted urea compounds
US6525046B1 (en) 2000-01-18 2003-02-25 Boehringer Ingelheim Pharmaceuticals, Inc. Aromatic heterocyclic compounds as antiinflammatory agents
WO2002066442A1 (en) 2001-02-15 2002-08-29 Boehringer Ingelheim Pharmaceuticals, Inc. Process for synthesis of heteroaryl-substituted urea compounds useful as antiinflammatory agents
JP2004530690A (ja) 2001-05-16 2004-10-07 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド 抗炎症性薬剤として有用なジアリールウレア誘導体
ATE360417T1 (de) 2001-07-11 2007-05-15 Boehringer Ingelheim Pharma Methode zur behandlung von zytokinvermittelten erkrankungen
SI1478358T1 (sl) 2002-02-11 2013-09-30 Bayer Healthcare Llc Sorafenib tozilat za zdravljenje bolezni, značilnih po abnormalni angiogenezi
US20040023961A1 (en) * 2002-02-11 2004-02-05 Bayer Corporation Aryl ureas with raf kinase and angiogenisis inhibiting activity
WO2003072569A1 (en) * 2002-02-25 2003-09-04 Boehringer Ingelheim Pharmaceuticals, Inc. 1,4-disubstituted benzofused cycloalkyl urea compounds useful in treating cytokine mediated diseases
AU2003224025A1 (en) 2002-04-05 2003-10-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg p38 kinase inhibitors for treating mucus hypersecretion
US20040110755A1 (en) 2002-08-13 2004-06-10 Boehringer Ingelheim Pharmaceuticals, Inc. Combination therapy with p38 MAP kinase inhibitors and their pharmaceutical compositions
EP1545535A4 (en) 2002-09-05 2008-06-04 Scios Inc TREATMENT OF PAIN BY INHIBITION OF P38 MAP KINASE
US7202257B2 (en) 2003-12-24 2007-04-10 Deciphera Pharmaceuticals, Llc Anti-inflammatory medicaments
US7144911B2 (en) 2002-12-31 2006-12-05 Deciphera Pharmaceuticals Llc Anti-inflammatory medicaments
WO2004078746A2 (en) 2003-02-28 2004-09-16 Bayer Pharmaceuticals Corporation 2-oxo-1,3,5-perhydrotriazapine derivatives useful in the treatment of hyper-proliferative, angiogenesis, and inflammatrory disorders
AU2004218463B2 (en) 2003-03-03 2009-07-16 Array Biopharma, Inc. p38 inhibitors and methods of use thereof
GB0308511D0 (en) 2003-04-14 2003-05-21 Astex Technology Ltd Pharmaceutical compounds
GB0320244D0 (en) 2003-05-06 2003-10-01 Aventis Pharma Inc Pyrazoles as inhibitors of tumour necrosis factor
US20070010529A1 (en) 2003-05-19 2007-01-11 Kanji Takahashi Nitrogenous heterocyclic compounds and medical use thereof
BRPI0413757A (pt) 2003-08-22 2006-10-31 Boehringer Ingelheim Pharma métodos para o tratamento de copd e da hipertensão pulmonar
EP1684762A4 (en) 2003-11-13 2009-06-17 Ambit Biosciences Corp UREA DERIVATIVES AS MODULATORS OF KINASE
WO2006028524A2 (en) 2004-04-29 2006-03-16 Pharmix Corporation Compositions and treatments for inhibiting kinase and/or hmg-coa reductase
WO2005110994A2 (en) 2004-04-30 2005-11-24 Bayer Pharmaceuticals Corporation Substituted pyrazolyl urea derivatives useful in the treatment of cancer
WO2005113511A1 (en) 2004-05-12 2005-12-01 Bristol-Myers Squibb Company Urea antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
ES2308523T3 (es) 2004-06-23 2008-12-01 Eli Lilly And Company Inhibidores de quinasa.
US20060035893A1 (en) 2004-08-07 2006-02-16 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
GB0423554D0 (en) 2004-10-22 2004-11-24 Cancer Rec Tech Ltd Therapeutic compounds
US7612200B2 (en) 2004-12-07 2009-11-03 Locus Pharmaceuticals, Inc. Inhibitors of protein kinases
JP2008524213A (ja) 2004-12-20 2008-07-10 アストラゼネカ・アクチエボラーグ 新規なピラゾール誘導体及びニコチン性アセチルコリン受容体のモジュレーターとしてのそれらの使用
AU2005321946B2 (en) 2004-12-23 2012-08-16 Deciphera Pharmaceuticals, Llc Enzyme modulators and treatments
US20090312349A1 (en) 2004-12-23 2009-12-17 Deciphera Pharmaceuticals, Llc Anti-inflammatory medicaments
GB0500435D0 (en) * 2005-01-10 2005-02-16 Novartis Ag Organic compounds
DE102005015253A1 (de) 2005-04-04 2006-10-05 Merck Patent Gmbh Pyrazolderivate
US7700620B2 (en) 2005-06-27 2010-04-20 Bristol-Myers Squibb Company C-linked cyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
DE102005037499A1 (de) 2005-08-09 2007-02-15 Merck Patent Gmbh Pyrazolderivate
WO2007038425A2 (en) 2005-09-27 2007-04-05 Regents Of The University Of Minnesota Anti-viral compouinds
EP1960394A2 (en) 2005-11-15 2008-08-27 Bayer HealthCare AG Pyrazolyl urea derivatives useful in the treatment of cancer
US20110195110A1 (en) 2005-12-01 2011-08-11 Roger Smith Urea compounds useful in the treatment of cancer
US8044049B2 (en) 2006-08-04 2011-10-25 Takeda Pharmaceutical Company Limited Fused heterocyclic derivative and use thereof
CN102112901B (zh) * 2008-07-31 2014-08-06 惠普开发有限公司 用于放大、调制和检测光信号的纳米线光学块设备
PE20110598A1 (es) * 2008-10-02 2011-08-31 Respivert Ltd Inhibidores de las enzimas de proteina cinasa activadas por mitogeno p38
MX2011006220A (es) * 2008-12-11 2011-06-28 Respivert Ltd Inhibidores de la proteina cinasa activada por el mitogeno p38.

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