GB0814302D0 - Compounds and methods - Google Patents

Compounds and methods

Info

Publication number
GB0814302D0
GB0814302D0 GBGB0814302.6A GB0814302A GB0814302D0 GB 0814302 D0 GB0814302 D0 GB 0814302D0 GB 0814302 A GB0814302 A GB 0814302A GB 0814302 D0 GB0814302 D0 GB 0814302D0
Authority
GB
United Kingdom
Prior art keywords
microns
methods
tissue
target tissue
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0814302.6A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coretherapix SL
Original Assignee
Coretherapix SL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39846672&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB0814302(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Coretherapix SL filed Critical Coretherapix SL
Priority to GBGB0814302.6A priority Critical patent/GB0814302D0/en
Publication of GB0814302D0 publication Critical patent/GB0814302D0/en
Priority to JP2011521575A priority patent/JP5623400B2/ja
Priority to BRPI0917571-7A priority patent/BRPI0917571B1/pt
Priority to EP09781530.2A priority patent/EP2323626B1/en
Priority to KR1020117004837A priority patent/KR101639827B1/ko
Priority to ES09781530.2T priority patent/ES2677005T3/es
Priority to CN2009801391387A priority patent/CN102170868A/zh
Priority to AU2009279086A priority patent/AU2009279086B2/en
Priority to MX2011001261A priority patent/MX2011001261A/es
Priority to PCT/EP2009/060171 priority patent/WO2010015665A2/en
Priority to CA2732785A priority patent/CA2732785C/en
Priority to CL2011000244A priority patent/CL2011000244A1/es
Priority to US13/425,041 priority patent/US20120195939A1/en
Priority to US13/736,267 priority patent/US20130189321A1/en
Priority to US13/836,102 priority patent/US20130309304A1/en
Priority to US13/873,812 priority patent/US8846099B2/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GBGB0814302.6A 2008-08-05 2008-08-05 Compounds and methods Ceased GB0814302D0 (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
GBGB0814302.6A GB0814302D0 (en) 2008-08-05 2008-08-05 Compounds and methods
PCT/EP2009/060171 WO2010015665A2 (en) 2008-08-05 2009-08-05 Compounds and methods
CA2732785A CA2732785C (en) 2008-08-05 2009-08-05 Parenteral pharmaceutical composition comprising microspheres and active ingredients for targeting particular tissue and/or/organ
AU2009279086A AU2009279086B2 (en) 2008-08-05 2009-08-05 Parenteral composition comprising microspheres with a diameter between 10 and 20 microns
MX2011001261A MX2011001261A (es) 2008-08-05 2009-08-05 Composicion parenteral que comprende microesferas con un diametro entre 10 y 20 micrometros.
EP09781530.2A EP2323626B1 (en) 2008-08-05 2009-08-05 Parenteral composition comprising microspheres with a diameter between 10 and 20 microns
KR1020117004837A KR101639827B1 (ko) 2008-08-05 2009-08-05 10 내지 20 미크론의 직경을 갖는 미세구를 포함하는 비경구형 조성물
ES09781530.2T ES2677005T3 (es) 2008-08-05 2009-08-05 Composición parenteral que comprende microesferas con un diámetro entre 10 y 20 micras
CN2009801391387A CN102170868A (zh) 2008-08-05 2009-08-05 包含介于10和20微米之间直径的微球的胃肠外给药组合物
JP2011521575A JP5623400B2 (ja) 2008-08-05 2009-08-05 直径１０〜２０μｍのマイクロスフェアを含む非経口組成物
BRPI0917571-7A BRPI0917571B1 (pt) 2008-08-05 2009-08-05 Formulação farmacêutica para administração intraarterial a montante de um tecido alvo compreendendo partículas esféricas contendo um ingrediente ativo e um excipiente biodegradável, e, usos da mesma
CL2011000244A CL2011000244A1 (es) 2008-08-05 2011-02-04 Formulacion farmaceutica intra-arterial que comprende particulas esfericas que contienen un factor de crecimiento y un excipiente biodegradable, en donde el diametro medio de dichas particulas es de 15-20 micrometros, con una desviacion estandar de (+/-) 1 micrometro en al menos 99% de las particulas; y su uso en el tratamiento de infarto al miocardio, trastorno cardiaco isquemico, entre otros.
US13/425,041 US20120195939A1 (en) 2008-08-05 2012-03-20 Parenteral composition comprising microspheres with a diameter between 10 and 20 microns
US13/736,267 US20130189321A1 (en) 2008-08-05 2013-01-08 Parental Composition Comprising Microsperes with a Diameter between 10 and 20 Microns
US13/836,102 US20130309304A1 (en) 2008-08-05 2013-03-15 Compounds and methods
US13/873,812 US8846099B2 (en) 2008-08-05 2013-04-30 Parenteral composition comprising microspheres with a diameter between 10 and 20 microns

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0814302.6A GB0814302D0 (en) 2008-08-05 2008-08-05 Compounds and methods

Publications (1)

Publication Number Publication Date
GB0814302D0 true GB0814302D0 (en) 2008-10-01

Family

ID=39846672

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0814302.6A Ceased GB0814302D0 (en) 2008-08-05 2008-08-05 Compounds and methods

Country Status (13)

Country Link
US (3) US20120195939A1 (enExample)
EP (1) EP2323626B1 (enExample)
JP (1) JP5623400B2 (enExample)
KR (1) KR101639827B1 (enExample)
CN (1) CN102170868A (enExample)
AU (1) AU2009279086B2 (enExample)
BR (1) BRPI0917571B1 (enExample)
CA (1) CA2732785C (enExample)
CL (1) CL2011000244A1 (enExample)
ES (1) ES2677005T3 (enExample)
GB (1) GB0814302D0 (enExample)
MX (1) MX2011001261A (enExample)
WO (1) WO2010015665A2 (enExample)

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GB0814302D0 (en) 2008-08-05 2008-10-01 Coretherapix Slu Compounds and methods
US10195252B2 (en) 2012-08-03 2019-02-05 University of Pittsburgh—of the Commonwealth System of Higher Education Recruitment of mensenchymal cells using controlled release systems
US9828603B2 (en) 2012-08-13 2017-11-28 Cedars Sinai Medical Center Exosomes and micro-ribonucleic acids for tissue regeneration
WO2014066545A1 (en) * 2012-10-26 2014-05-01 Cedars-Sinai Medical Center Therapeutic cells depleted of specific subpopulations of cells for use in tissue repair of regeneration
US10526581B2 (en) * 2013-01-24 2020-01-07 Bernardo Nadal-Ginard Modulation of cardiac stem-progenitor cell differentiation, assays and uses thereof
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US11357799B2 (en) 2014-10-03 2022-06-14 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
CN104650333B (zh) * 2015-02-05 2016-08-24 浙江大学 聚乳酸/氢化聚丁二烯热塑性超分子弹性体及其制备方法
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EP3402543B1 (en) 2016-01-11 2021-09-08 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction
CN109414266B (zh) 2016-05-04 2021-07-23 阿克瑞特医学治疗有限公司 具有狭缝状图案的栓塞微导管头部
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EP3515459A4 (en) 2016-09-20 2020-08-05 Cedars-Sinai Medical Center CELLS DERIVED FROM CARDIOSPHERES AND THEIR EXTRACELLULAR VESICLES TO DELAY OR REVERSE AGING AND AGE-RELATED DISORDERS
US11759482B2 (en) 2017-04-19 2023-09-19 Cedars-Sinai Medical Center Methods and compositions for treating skeletal muscular dystrophy
CN111447882B (zh) 2017-11-02 2024-05-24 阿克瑞特医学治疗有限公司 具有一体式过滤器的栓塞导管
US11660355B2 (en) 2017-12-20 2023-05-30 Cedars-Sinai Medical Center Engineered extracellular vesicles for enhanced tissue delivery
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Also Published As

Publication number Publication date
CN102170868A (zh) 2011-08-31
JP2011529946A (ja) 2011-12-15
AU2009279086A1 (en) 2010-02-11
CL2011000244A1 (es) 2011-07-15
KR20110051212A (ko) 2011-05-17
EP2323626B1 (en) 2018-04-11
WO2010015665A2 (en) 2010-02-11
BRPI0917571A2 (pt) 2020-08-11
US20130189321A1 (en) 2013-07-25
CA2732785A1 (en) 2010-02-11
KR101639827B1 (ko) 2016-07-14
CA2732785C (en) 2016-11-22
BRPI0917571B1 (pt) 2022-01-04
US20130315997A1 (en) 2013-11-28
US20120195939A1 (en) 2012-08-02
EP2323626A2 (en) 2011-05-25
ES2677005T3 (es) 2018-07-27
MX2011001261A (es) 2011-08-08
WO2010015665A3 (en) 2010-10-07
US8846099B2 (en) 2014-09-30
JP5623400B2 (ja) 2014-11-12
AU2009279086B2 (en) 2014-05-22

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