FR3112480A1 - Composition aqueuse ayant des propriétés trophiques vis-à-vis de cellules de la peau et apte à faciliter la formulation de produits cosmétiques ou vétérinaires - Google Patents
Composition aqueuse ayant des propriétés trophiques vis-à-vis de cellules de la peau et apte à faciliter la formulation de produits cosmétiques ou vétérinaires Download PDFInfo
- Publication number
- FR3112480A1 FR3112480A1 FR2007631A FR2007631A FR3112480A1 FR 3112480 A1 FR3112480 A1 FR 3112480A1 FR 2007631 A FR2007631 A FR 2007631A FR 2007631 A FR2007631 A FR 2007631A FR 3112480 A1 FR3112480 A1 FR 3112480A1
- Authority
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- France
- Prior art keywords
- composition according
- composition
- advantageously
- aqueous composition
- weight
- Prior art date
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- Granted
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- 239000002537 cosmetic Substances 0.000 title claims description 21
- 238000009472 formulation Methods 0.000 title description 13
- 210000004927 skin cell Anatomy 0.000 title description 6
- 230000001228 trophic effect Effects 0.000 title description 3
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- 229930006000 Sucrose Natural products 0.000 claims abstract description 19
- 239000005720 sucrose Substances 0.000 claims abstract description 19
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims abstract description 17
- 229960002648 alanylglutamine Drugs 0.000 claims abstract description 17
- 229910000397 disodium phosphate Inorganic materials 0.000 claims abstract description 15
- 235000019800 disodium phosphate Nutrition 0.000 claims abstract description 15
- 229940054269 sodium pyruvate Drugs 0.000 claims abstract description 15
- 239000001632 sodium acetate Substances 0.000 claims abstract description 14
- 235000017281 sodium acetate Nutrition 0.000 claims abstract description 14
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims abstract description 12
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims abstract description 12
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- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims abstract description 12
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- MUPFEKGTMRGPLJ-WSCXOGSTSA-N gentianose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-WSCXOGSTSA-N 0.000 claims abstract description 6
- QWIZNVHXZXRPDR-WSCXOGSTSA-N melezitose Chemical compound O([C@@]1(O[C@@H]([C@H]([C@@H]1O[C@@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O)CO)CO)[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O QWIZNVHXZXRPDR-WSCXOGSTSA-N 0.000 claims abstract description 6
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 claims abstract description 6
- UQZIYBXSHAGNOE-XNSRJBNMSA-N stachyose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO[C@@H]3[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O3)O)O2)O)O1 UQZIYBXSHAGNOE-XNSRJBNMSA-N 0.000 claims abstract description 6
- FLUADVWHMHPUCG-SWPIJASHSA-N verbascose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO[C@@H]3[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO[C@@H]4[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O4)O)O3)O)O2)O)O1 FLUADVWHMHPUCG-SWPIJASHSA-N 0.000 claims abstract description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 32
- 241001465754 Metazoa Species 0.000 claims description 25
- HJCMDXDYPOUFDY-WHFBIAKZSA-N Ala-Gln Chemical compound C[C@H](N)C(=O)N[C@H](C(O)=O)CCC(N)=O HJCMDXDYPOUFDY-WHFBIAKZSA-N 0.000 claims description 14
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims description 11
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- 150000001875 compounds Chemical class 0.000 description 19
- -1 diethylhexyl Chemical group 0.000 description 19
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- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 14
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- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 229940010747 sodium hyaluronate Drugs 0.000 description 1
- 229940057950 sodium laureth sulfate Drugs 0.000 description 1
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 description 1
- 229940045885 sodium lauroyl sarcosinate Drugs 0.000 description 1
- 235000011008 sodium phosphates Nutrition 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 description 1
- 229940001941 soy protein Drugs 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 238000002798 spectrophotometry method Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- WWUZIQQURGPMPG-KRWOKUGFSA-N sphingosine Chemical compound CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)CO WWUZIQQURGPMPG-KRWOKUGFSA-N 0.000 description 1
- 239000004544 spot-on Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- ARCJQKUWGAZPFX-UHFFFAOYSA-N stilbene oxide Chemical compound O1C(C=2C=CC=CC=2)C1C1=CC=CC=C1 ARCJQKUWGAZPFX-UHFFFAOYSA-N 0.000 description 1
- 235000021286 stilbenes Nutrition 0.000 description 1
- 150000001629 stilbenes Chemical class 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 125000005555 sulfoximide group Chemical group 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 229960003080 taurine Drugs 0.000 description 1
- 208000009056 telangiectasis Diseases 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 235000019303 thiodipropionic acid Nutrition 0.000 description 1
- 150000003573 thiols Chemical class 0.000 description 1
- 229940094937 thioredoxin Drugs 0.000 description 1
- 108060008226 thioredoxin Proteins 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 229930003802 tocotrienol Natural products 0.000 description 1
- 239000011731 tocotrienol Substances 0.000 description 1
- 235000019148 tocotrienols Nutrition 0.000 description 1
- ZRVDANDJSTYELM-FXAWDEMLSA-N totarol Chemical compound CC([C@@H]1CC2)(C)CCC[C@]1(C)C1=C2C(C(C)C)=C(O)C=C1 ZRVDANDJSTYELM-FXAWDEMLSA-N 0.000 description 1
- 229940074347 totarol Drugs 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- QURCVMIEKCOAJU-UHFFFAOYSA-N trans-isoferulic acid Natural products COC1=CC=C(C=CC(O)=O)C=C1O QURCVMIEKCOAJU-UHFFFAOYSA-N 0.000 description 1
- ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 description 1
- ZRVDANDJSTYELM-UHFFFAOYSA-N trans-totarol Natural products C1CC2C(C)(C)CCCC2(C)C2=C1C(C(C)C)=C(O)C=C2 ZRVDANDJSTYELM-UHFFFAOYSA-N 0.000 description 1
- SZEMGTQCPRNXEG-UHFFFAOYSA-M trimethyl(octadecyl)azanium;bromide Chemical compound [Br-].CCCCCCCCCCCCCCCCCC[N+](C)(C)C SZEMGTQCPRNXEG-UHFFFAOYSA-M 0.000 description 1
- 229910021642 ultra pure water Inorganic materials 0.000 description 1
- 239000012498 ultrapure water Substances 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 229940116269 uric acid Drugs 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 239000007762 w/o emulsion Substances 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011670 zinc gluconate Substances 0.000 description 1
- 229960000306 zinc gluconate Drugs 0.000 description 1
- 235000011478 zinc gluconate Nutrition 0.000 description 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 1
- 239000011686 zinc sulphate Substances 0.000 description 1
- 235000009529 zinc sulphate Nutrition 0.000 description 1
- 229910052726 zirconium Inorganic materials 0.000 description 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Cosmetics (AREA)
Abstract
Description
- du pyruvate de sodium ;
- de l’hydrogénophosphate de sodium ;
- de l’acétate de sodium ;
- du dipeptide L-Alanyl-L-Glutamine ;
- un sucre choisi parmi le saccharose, le tréhalose, l’isotréhalose, l’isosaccharose, le mélézitose, le gentianose, le raffinose, l’erlose, le stachyose, le verbascose, et leurs mélanges ; et
- de l’eau,
- permet de stimuler la croissance des cellules de la peau ;
-est cytocompatible ;
- comprend ou est constituée de composants biomimétiques ;
- peuvent être bénéfiques pour le microbiote cutané ;
-permettent d’obtenir des compositions isotoniques avec l’eau des cellules tout en évitant le recours aux électrolytes ;
-se prêtent à la formulation avec d’autres composants de la formule, dont ils contribuent à en améliorer la stabilité.
- du pyruvate de sodium ;
- de l’hydrogénophosphate de sodium ;
- de l’acétate de sodium ;
- du dipeptide L-Alanyl-L-Glutamine ;
- un sucre choisi parmi le saccharose, le tréhalose, l’isotréhalose, l’isosaccharose, le mélézitose, le gentianose, le raffinose, l’erlose, le stachyose, le verbascose, et leurs mélanges ; et
- de l’eau.
- du pyruvate de sodium ;
- de l’hydrogénophosphate de sodium ;
- de l’acétate de sodium ;
- du dipeptide L-Alanyl-L-Glutamine ;
- un sucre choisi parmi le saccharose, le tréhalose, l’isotréhalose, l’isosaccharose, le mélézitose, le gentianose, le raffinose, l’erlose, le stachyose, le verbascose, et leurs mélanges ; et
- de l’eau.
- comprise entre 10 et 28, en ce qui concerne le potentiel redox ;
- comprise entre 5 et 8, en ce qui concerne le pH ; et
- une résistivité substantiellement comprise entre 8000 ohms (Ω).cm et 80 Ω.cm avantageusement entre 500 et 100 Ω.cm.
- le filtre correspondant à la désignation INCI disodium phenyl dibenzimidazole tetrasulfonate, notamment disponible sous la dénomination Neo Heliopan®AP (Symrise) ;
- le filtre correspondant à la désignation INCI phenylbenzimidazole sulfonic acid, notamment disponible sous la dénomination Neo Heliopan®hydro (Symrise), de préférence en combinaison avec un acide aminé basique, avantageusement de l’arginine. En pratique, l’acide aminé basique représente entre 0,5 et 2% en poids de la composition, de préférence entre 1 et 1,5%.
- plusieurs matières premières de la gamme CETIOL®commercialisées par la société BASF, notamment le CETIOL®RLF, CETIOL®B, CETIOL®CC, CETIOL®O, CETIOL®C5, CETIOL®AB, CETIOL®SENSOFT correspondant respectivement aux désignations INCI caprylyl caprylate/caprate, dibutyl adipate, dicaprylyl carbonate, dicaprylyl ether, coco-caprylate, C12-15 alkyl benzoate, propylheptyl caprylate ;
- le DUBTMDIS commercialisé par la société STEARINE DUBOIS correspondant à la désignation INCI diisopropyl sebacate ;
- Le MIGLYOL®8810 commercialisé par la société IOI Oleo GmbH correspondant à la désignation INCI butylene glycol dicaprylate/dicaprate.
- le butyloctyl salicylate (INCI), photostabilisant représentant avantageusement entre 0,01% et 10% en poids de la composition, encore plus avantageusement ente 0,1% et 2%. Cette matière première est par exemple commercialisée par la société HALLSTAR sous le nom de Hallbrite®BHB ;
- le benzotriazolyl dodecyl p-cresol (INCI), photostabilisant représentant avantageusement entre 0,01% et 10% en poids de la composition, encore plus avantageusement entre 0,1% et 2%. Cette matière première est par exemple commercialisée par la société BASF sous le nom de TINOGARD®TL ;
- le pongamol (INCI), molécule végétale absorbant dans les UV-A, représentant avantageusement entre 0,5 et 2% en poids de la composition, encore plus avantageusement de l’ordre de 1%. A titre d’exemple, la matière première Pongamia Extract commercialisée par la société GIVAUDAN peut être utilisée dans le cadre la présente invention ;
- l’ethylhexyl methoxycrylene (INCI), photostabilisant, solubilisant et « booster » de SPF représentant avantageusement entre 1% et 5% en poids de la composition. La matière première SolaStay®S1 commercialisée par la société HALLSTAR peut être utilisée dans le cadre de la présente invention ;
- un copolymère de styrène acrylate (INCI : styrene/acrylate copolymer), représentant de préférence entre 1% et 10% en poids de la composition selon l’invention. Les matières premières SunSpheres®H53 et SunSpheres®PGL Polymer, commercialisées par la société DOW CHEMICALS, peuvent être utilisées dans le cadre de la présente invention ;
- le diethylhexyl syringylidene malonate (INCI), représentant avantageusement entre 1% et 10% en poids de la composition. La matière première OXYNET®ST, commercialisée par la société MERCK, peut être utilisée dans le cadre de la présente invention ;
- un polyester hydrodispersible, correspondant aux désignations INCI polyester-5 (and) Sodium silicoaluminate, représentant avantageusement entre 1% et 10% en poids de la composition, notamment l’EASTMANN AQTM38S Polymer commercialisé par la société SAFIC-ALCAN ;
- un copolymère d'acrylate ayant une température de transition vitreuse de -5°C à -15°C telle que mesurée par calorimétrie différentielle à balayage, ledit copolymère représentant avantageusement entre 1% et 10% en poids de la composition. Par exemple, un polymère correspondant à la désignation INCI Acrylate copolymer, tel que la matière première EPITEX 66, commercialisée par la société DOW CHEMICALS, peut être utilisée dans le cadre de la présente invention.
- le EVO-100™commercialisé par la société ARCHER DANIELS MIDLAND COMPANY et correspondant à la désignation INCI propylene glycol ;
- le ZEMEA™commercialisé par la société DUPONT-TATE & LYLE BIOPRODUCTS et correspondant à la désignation INCI 1,2-propanediol ;
- le DUB DIOL™commercialisé par la société STEARINERIE DUBOIS et correspondant à la désignations INCI 2-methyl-1,3-propanediol ;
- l’Hydrolite-5™, Hydrolite-6™, Hydrolite-8™et le SymClariol 344028™commercialisés par la société SYMRISE et correspondant respectivement aux désignations INCI 1,2-pentanediol, 1,2-hexanediol, caprylyl glycol et 1,2-decanediol ;
- l’Hexasol™commercialisé par la société ARKEMA et correspondant à la désignation INCI hexylene glycol.
- le potassium sorbate (INCI), le sodium benzoate (INCI) et le benzyl alcohol (INCI) commercialisés par la société AZELIS UK sous la dénomination Paratexin™KS, Paratexin™SBG et Paratexin™BA, respectivement ;
- le p-anisic acid (INCI) et levulinic acid (INCI) commercialisés par la société COSPHATEC GMBH sous la dénomination Cosphaderm™et Cophaderm™LA-T, respectivement ;
- le dehydroacetic acid (INCI) et le polyaminoprypyl guanide (INCI), commercialisés par la société LONZA sous la dénomination Geogard™111A et Cosmocil™CQ, respectivement ;
- le phenoxyethanol (INCI) commercialisé par la société CLARIANT INTERNATIONAL LTD sous la dénomination Phenoxetol™.
- un agent antiradicalaire préservant les structures cellulaires, tel que par exemple la vitamine E et/ou ses dérivés liposolubles ou hydrosolubles, en particulier le tocotriénol et/ou le tocophérol, représentant avantageusement entre 0,001% et 10% en poids de la composition, encore plus avantageusement entre 0,02% et 2%, de préférence 0,04% ;
- un agent limitant l'immunosuppression, tel que par exemple la vitamine PP, représentant avantageusement entre 0,001% et 1% en poids de la composition, de préférence entre 0,01% et 0,3%;
- un agent protecteur de la protéine p53, tel que par exemple l'épigallocatéchine gallate (EGCG), représentant avantageusement entre 0,001% et 0,1% en poids de la composition, de préférence entre 0,005% et 0,05%.
- de l’acide α-lipoïque ou l’un de ses sels ;
- un dérivé de vitamine C choisi parmi l’éthyle acide ascorbique et l’ascorbate de sodium ou leur mélange ; et
- de l’acide hyaluronique, dont le poids moléculaire (Mw) est avantageusement compris entre 0,5 et 15 kDa, de préférence 0,5 et 10 kDa.
- de l’azéilate de lysine, ou d’autres dérivés ou sels de l’acide azélaïque ;
- de l’andrographolide, notamment l’extrait d’Andrographis paniculatacorrespondant à la désignation INCIAndrographis paniculataleaf extract ;
- de l’acide ascorbique natif (vitamine C) ou ses dérivés, notamment les dérivés correspondant aux INCI Ascorbyl Glucoside, Ethyl ascorbic acid, Ascorbyl methylsilanol pectinate, Sodium ascorbyl phosphate et Ascorbyl tetraisopalmitate, avantageusement l’ascorbyl glucoside ;
- de l’arbutine ou un extrait végétal la contenant, notamment l’extrait de busserole correspondant à la désignation INCIArctostaphylos uva-ursileaf extract ;
- de la glabridine ou un extrait végétal la contenant, notamment les extraits de réglisse correspondant à la désignation INCIGlycyrrhiza glabraroot extract,Glycyrrhiza inflataroot extract,Glycyrrhiza uralensisroot extract ;
- les peptides biomimétiques correspondant aux désignations INCI hexapeptide 2 et/ou nonapeptide-1 ;
- un extrait aqueux d'une algue dénomméePalmaria palmata, notamment l’extrait correspondant à la désignation INCIPalmaria palmataextract ;
- le 4-n-butylresorcinol ;
- de la vitamine PP, également appelée niacinamide ou nicotinamide, et ses dérivés;
- ou leurs mélanges.
- de l’hypotaurine (acide aminoethanesulfinique) ;
- un extrait des alguesLaminaria ochroleuca,Blidingia minimaouLaminaria saccharina;
- un extrait de la planteZanthoxylum alatum;
- du panthénol ;
- un extrait de bois de cade ;
- un extrait de Boldo ;
- un extrait de Reine des prés ;
- un extrait d’huile de karanja issue duPongamia glabra;
- des paraffines linéaires.
INCI | % |
Composition aqueuse selon l’invention | |
Saccharose | 3,8944 |
Disodium Phosphate | 2,6284 |
L-Alanyl L-Glutamine | 0,0662 |
Sodium Acetate | 0,0195 |
Sodium Pyruvate | 0,0036 |
Autres composants de la composition selon l’invention | |
Eau | 68,8749 |
Propanediol | 5,00 |
Dicaprylyl carbonate | 4,9985 |
Alcohol | 4,80 |
Urea | 2,00 |
C14-22 Alcohols | 1,60 |
Capryloyl Glycine | 1,20 |
Dipalmitoyl Hydroxyproline | 1,00 |
Potassium Phosphate | 0,75 |
Sodium Lactate | 0,6 |
Leuconostoc/Radish Root Ferment Filtrate | 0,45 |
C12-20 Alkyl Glucoside | 0,40 |
Xanthan Gum | 0,40 |
Cetearyl Alcohol | 0,325 |
Sodium Hydroxyde | 0,283 |
Sodium Stearoyl Glutamate | 0,20 |
Salix Nigra (Willow) Bark Extract | 0,18 |
Coco-Glucoside | 0,175 |
Carrageenan | 0,15 |
INCI | % |
Composition aqueuse selon l’invention | |
Saccharose | 3,9166 |
L-Alanyl L-Glutamine | 0,0666 |
Sodium Acetate | 0,0196 |
Disodium Phosphate | 0,0185 |
Sodium Pyruvate | 0,0036 |
Autres composants de la composition selon l’invention | |
Eau | 79,64225 |
Sodium Laureth Sulfate | 4,9 |
Coco-betaine | 3,9 |
Sodium Lauroyl Sarcosinate | 2,7 |
Glycerin | 1 |
Methypropanediol | 1 |
Coco-glucoside | 0,75 |
Glyceryl Oleate | 0,75 |
Disodium EDTA | 0,5 |
Parfum | 0,23 |
Caprylyoyl Glycine | 0,2 |
Citric acid | 0,125 |
Citric Acid | 0,11 |
Copper Sulfate | 0,07 |
Xylitylglucoside | 0,04 |
Anhydroxlitol | 0,028 |
Xylitol | 0,012 |
Niacinamide | 0,01 |
Glucose | 0,004 |
Fructooligosaccharides | 0,001 |
Mannitol | 0,001 |
Xylitol | 0,001 |
Tocopherol | 0,0005 |
Hydrogenated Palm Glycerides Citrate | 0,00025 |
Rhamnose | 0,0001 |
INCI | % |
Composition aqueuse selon l’invention | |
Saccharose | 5,7883 |
L-Alanyl L-Glutamine | 0,0984 |
Sodium Acetate | 0,029 |
Disodium Phosphate | 0,0274 |
Sodium Pyruvate | 0,0053 |
Autres composants de la composition selon l’invention | |
Eau | 91,1651 |
PEG-6 Caprylic/Capric Glycerides | 2,5 |
Disodium EDTA | 0,2 |
Cetrimonium Bromide | 0,075 |
Propylene Glycol | 0,074 |
Citric Acid | 0,0375 |
Composant (INCI) | Composition selon l’invention (%) |
Saccharose | 6 % |
Sodium pyruvate | 0,0055% |
L-Alanyl-L-Glutamine | 0,150% |
Disodium phosphate | 0,0284% |
Sodium acetate | 0,03% |
Eau | qsp 100% |
pH | 7.24 |
Osmolarité | 244 |
Ingrédient | Fle 1 (composition selon l’invention) | Fle 2 |
Eau | 68,8749 | 68,8749 |
Propanediol | 5 | 5 |
Dicaprylyl carbonate | 4,9985 | 4,9985 |
Alcohol | 4,8 | 4,8 |
Saccharose | 3,8944 | - |
Glucose | - | 3,8944 |
Disodium Phosphate | 2,6284 | 2,6284 |
Urea | 2 | 2 |
C14-22 Alcohols | 1,6 | 1,6 |
Capryloyl Glycine | 1,2 | 1,2 |
Dipalmitoyl Hydroxyproline | 1 | 1 |
Potassium Phosphate | 0,75 | 0,75 |
Sodium Lactate | 0,6 | 0,6 |
Leuconostoc/Radish Root Ferment Filtrate | 0,45 | 0,45 |
C12-20 Alkyl Glucoside | 0,4 | 0,4 |
Xanthan Gum | 0,4 | 0,4 |
Cetearyl Alcohol | 0,325 | 0,325 |
Sodium Hydroxyde | 0,283 | 0,283 |
Sodium Stearoyl Glutamate | 0,2 | 0,2 |
Salix Nigra (Willow) Bark Extract | 0,18 | 0,18 |
Coco-Glucoside | 0,175 | 0,175 |
Carrageenan | 0,15 | 0,15 |
L-Alanyl L-Glutamine | 0,0662 | 0,0662 |
Sodium Acetate | 0,0195 | 0,0195 |
Sodium Pyruvate | 0,0036 | 0,0036 |
Tocopherol | 0,0015 | 0,0015 |
- après incubation en étuve à 80°C pendant 24 heures ;
- après incubation en étuve à 50°C pendant un mois ; et
- après incubation en étuve à 40°C pendant deux mois ;
car il a été constaté visuellement qu’il y avait une évolution limitée en couleur.
- L* représente la clarté, du noir au blanc.
- a* représente l'axe rouge et l'axe vert en passant par le gris.
- b* représente l’axe jaune et l'axe bleu en passant par le gris.
Fle | ΔE*ab(D65) | L*(D65) | Axe a* | Axe b* |
Fle 1 (Témoin) | --- | --- | --- | --- |
Fle 2 | 1,79 | Plus foncé | Plus vert | Plus jaune |
Fle | 24H80°C | ΔE*ab(D65) | L*(D65) | Axe a* | Axe b* |
Fle 1 (Témoin) | Oui | ---- | ---- | ---- | ---- |
Fle 2 | Oui | 38,98 | Plus foncé | Moins vert | Plus jaune |
Fle | 1M50°C | ΔE*ab(D65) | L*(D65) | Axe a* | Axe b* |
Fle 1 (Témoin) | Oui | ---- | ---- | ---- | ---- |
Fle 2 | Oui | 40,50 | Plus foncé | Moins vert | Plus jaune |
Fle | 2M40°C | ΔE*ab(D65) | L*(D65) | Axe a* | Axe b* |
Fle 1 (Témoin) | Oui | ---- | ---- | ---- | ---- |
Fle 2 | Oui | 25,18 | Plus foncé | Moins vert | Plus jaune |
Claims (12)
- Composition aqueuse comprenant :
- du pyruvate de sodium ;
- de l’hydrogénophosphate de sodium ;
-de l’acétate de sodium ;
- du dipeptide L-Alanyl-L-Glutamine ;
-un sucre choisi parmi le saccharose, le tréhalose, l’isotréhalose, l’isosaccharose, le mélézitose, le gentianose, le raffinose, l’erlose, le stachyose, le verbascose, et leurs mélanges. - Composition aqueuse selon la revendication 1, caractérisée en ce que le sucre est choisi parmi le saccharose et le tréhalose, avantageusement le sucre est le saccharose.
- Composition aqueuse selon la revendication 1, caractérisée en ce que le pyruvate de sodium représente de 0,0001% à 0,1% en poids de la composition, de préférence de 0,001 à 0,01%.
- Composition aqueuse selon l’une des revendications précédentes, caractérisée en ce que l’hydrogénophosphate de sodium représente de 0,01% à 10% en poids de la composition, de préférence de 0,01% à 5%.
- Composition aqueuse selon l’une des revendications précédentes, caractérisée en ce que l’acétate de sodium représente de 0,0001% à 0,1% en poids de la composition, de préférence de 0,001 à 0,05%.
- Composition aqueuse selon l’une des revendications précédentes, caractérisée en ce que le dipeptide L-Alanyl-L-glutamine représente entre 0,001% et 5% en poids de la composition, avantageusement entre 0,01% et 2%.
- Composition aqueuse selon l’une des revendications précédentes, caractérisée en ce que le sucre représente entre 0,01% et 15% en poids de la composition, avantageusement entre 0,1% et 7%.
- Composition aqueuse selon une des revendications précédentes, caractérisée en ce que l’eau représente au moins 50% en poids de la composition, avantageusement au moins 70%, de préférence au moins 90%.
- Composition aqueuse selon l’une des revendications 1 à 8, ladite composition étant sous la forme d’une émulsion H/E, d’une émulsion E/H, d’un gel, d’une lotion ou d’une composition pulvérisable.
- Composition aqueuse selon l’une des revendications 1 à 9, caractérisée en ce qu’il s’agit d’une composition cosmétique.
- Composition aqueuse selon l’une des revendications 1 à 10, pour son utilisation en hygiène corporelle ou dermo-pharmaceutique ou vétérinaire..
- Composition aqueuse pour son utilisation selon la revendication 11, comme nettoyant auriculaire chez l’animal, avantageusement l’animal domestique.
Priority Applications (2)
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FR2007631A FR3112480B1 (fr) | 2020-07-20 | 2020-07-20 | Composition aqueuse ayant des propriétés trophiques vis-à-vis de cellules de la peau et apte à faciliter la formulation de produits cosmétiques ou vétérinaires |
PCT/FR2021/051275 WO2022018347A1 (fr) | 2020-07-20 | 2021-07-08 | Composition aqueuse ayant des propriétés trophiques vis-a-vis de cellules de la peau et apte à faciliter la formulation de produits cosmétiques ou vétérinaires |
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FR2007631A FR3112480B1 (fr) | 2020-07-20 | 2020-07-20 | Composition aqueuse ayant des propriétés trophiques vis-à-vis de cellules de la peau et apte à faciliter la formulation de produits cosmétiques ou vétérinaires |
FR2007631 | 2020-07-20 |
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Citations (5)
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FR2780887A1 (fr) | 1998-07-08 | 2000-01-14 | Jean Noel Thorel | Solution aqueuse saline et mineralisee, et son utilisation en cosmetique et dermo-pharmacie |
EP1484051A2 (fr) | 2003-06-05 | 2004-12-08 | L'oreal | Utilisation d'au moins un filtre de la lumière bleue pour préserver le capital de caroténoides endogènes de la peau; nouveaux filtres de la lumière bleue; compositions cosmétiques |
FR2865398A1 (fr) | 2004-01-23 | 2005-07-29 | Jean Noel Thorel | Compositions destinees a la protection cellulaire vis-a-vis des uva, de la peau, et/ou des phaneres. |
US20120121534A1 (en) * | 2009-07-27 | 2012-05-17 | Jean-Noel Thorel | Injectable composition combining a filling agent and a fibroblast growth medium |
FR3072285A1 (fr) | 2017-10-12 | 2019-04-19 | Jean-Noel Thorel | Solution aqueuse saline mineralisee et pourvue d'activite antioxydante, et son utilisation en dermocosmetique et dermopharmacie |
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2020
- 2020-07-20 FR FR2007631A patent/FR3112480B1/fr active Active
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2021
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FR2780887A1 (fr) | 1998-07-08 | 2000-01-14 | Jean Noel Thorel | Solution aqueuse saline et mineralisee, et son utilisation en cosmetique et dermo-pharmacie |
EP1484051A2 (fr) | 2003-06-05 | 2004-12-08 | L'oreal | Utilisation d'au moins un filtre de la lumière bleue pour préserver le capital de caroténoides endogènes de la peau; nouveaux filtres de la lumière bleue; compositions cosmétiques |
FR2865398A1 (fr) | 2004-01-23 | 2005-07-29 | Jean Noel Thorel | Compositions destinees a la protection cellulaire vis-a-vis des uva, de la peau, et/ou des phaneres. |
US20120121534A1 (en) * | 2009-07-27 | 2012-05-17 | Jean-Noel Thorel | Injectable composition combining a filling agent and a fibroblast growth medium |
FR3072285A1 (fr) | 2017-10-12 | 2019-04-19 | Jean-Noel Thorel | Solution aqueuse saline mineralisee et pourvue d'activite antioxydante, et son utilisation en dermocosmetique et dermopharmacie |
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