FR2997952B1 - Composes anioniques substitues constitues d'un squelette forme d'un nombre discret d'unites saccharidiques - Google Patents

Composes anioniques substitues constitues d'un squelette forme d'un nombre discret d'unites saccharidiques

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Publication number
FR2997952B1
FR2997952B1 FR1260808A FR1260808A FR2997952B1 FR 2997952 B1 FR2997952 B1 FR 2997952B1 FR 1260808 A FR1260808 A FR 1260808A FR 1260808 A FR1260808 A FR 1260808A FR 2997952 B1 FR2997952 B1 FR 2997952B1
Authority
FR
France
Prior art keywords
discrete number
anionic compounds
substituted anionic
skeletal form
saccharidic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1260808A
Other languages
English (en)
Other versions
FR2997952A1 (fr
Inventor
Gerard Soula
Emmanuel Dauty
Richard Charvet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adocia SAS
Original Assignee
Adocia SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adocia SAS filed Critical Adocia SAS
Priority to FR1260808A priority Critical patent/FR2997952B1/fr
Priority to SG11201503598QA priority patent/SG11201503598QA/en
Priority to EP13801655.5A priority patent/EP2920200A1/fr
Priority to CN201380059092.4A priority patent/CN104902922B/zh
Priority to AU2013346624A priority patent/AU2013346624B2/en
Priority to BR112015010797-4A priority patent/BR112015010797A2/pt
Priority to AU2013346623A priority patent/AU2013346623A1/en
Priority to SG10202112306UA priority patent/SG10202112306UA/en
Priority to BR112015010799-0A priority patent/BR112015010799B1/pt
Priority to KR1020217001290A priority patent/KR102367083B1/ko
Priority to CA2889552A priority patent/CA2889552C/fr
Priority to EA201590937A priority patent/EA201590937A1/ru
Priority to DK13801658.9T priority patent/DK2919804T3/en
Priority to US14/079,516 priority patent/US9700599B2/en
Priority to KR1020207029334A priority patent/KR20200121381A/ko
Priority to CN202010210296.5A priority patent/CN111494638A/zh
Priority to EP18154006.3A priority patent/EP3332810B1/fr
Priority to SG10201703742SA priority patent/SG10201703742SA/en
Priority to US14/079,437 priority patent/US20140187499A1/en
Priority to KR1020157015765A priority patent/KR20150084056A/ko
Priority to PCT/FR2013/052736 priority patent/WO2014076423A1/fr
Priority to KR1020207019459A priority patent/KR102205512B1/ko
Priority to JP2015542338A priority patent/JP6322642B2/ja
Priority to MX2015005423A priority patent/MX2015005423A/es
Priority to CA2889345A priority patent/CA2889345A1/fr
Priority to JP2015542337A priority patent/JP2016505523A/ja
Priority to CN201711087798.8A priority patent/CN107952065A/zh
Priority to PCT/FR2013/052733 priority patent/WO2014076422A1/fr
Priority to ES13801658.9T priority patent/ES2670969T3/es
Priority to PL13801658T priority patent/PL2919804T3/pl
Priority to EP13801658.9A priority patent/EP2919804B1/fr
Priority to MX2015005786A priority patent/MX360107B/es
Priority to EA201590944A priority patent/EA034393B1/ru
Priority to CN201380059136.3A priority patent/CN104903341B/zh
Priority to KR1020157015793A priority patent/KR20150082640A/ko
Publication of FR2997952A1 publication Critical patent/FR2997952A1/fr
Application granted granted Critical
Publication of FR2997952B1 publication Critical patent/FR2997952B1/fr
Priority to IL238303A priority patent/IL238303B/en
Priority to IL238446A priority patent/IL238446B/en
Priority to SA515360428A priority patent/SA515360428B1/ar
Priority to SA515360426A priority patent/SA515360426B1/ar
Priority to ZA2015/03293A priority patent/ZA201503293B/en
Priority to HK16101604.8A priority patent/HK1213493A1/zh
Priority to HK16101679.8A priority patent/HK1213907A1/zh
Priority to US15/410,524 priority patent/US20170143835A1/en
Priority to US15/609,670 priority patent/US10583175B2/en
Priority to JP2017207105A priority patent/JP2018021075A/ja
Priority to AU2018204764A priority patent/AU2018204764A1/en
Priority to AU2018208773A priority patent/AU2018208773B2/en
Priority to HK18111528.8A priority patent/HK1252137A1/zh
Priority to IL261726A priority patent/IL261726A/en
Priority to JP2019087751A priority patent/JP7332139B2/ja
Priority to US16/687,339 priority patent/US10646551B2/en
Priority to US16/848,640 priority patent/US10881716B2/en
Priority to IL274077A priority patent/IL274077A/en
Priority to AU2020203078A priority patent/AU2020203078A1/en
Priority to ZA2020/03132A priority patent/ZA202003132B/en
Priority to US17/096,178 priority patent/US11324808B2/en
Priority to JP2023088245A priority patent/JP2023099873A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR1260808A 2012-11-13 2012-11-13 Composes anioniques substitues constitues d'un squelette forme d'un nombre discret d'unites saccharidiques Active FR2997952B1 (fr)

Priority Applications (57)

Application Number Priority Date Filing Date Title
FR1260808A FR2997952B1 (fr) 2012-11-13 2012-11-13 Composes anioniques substitues constitues d'un squelette forme d'un nombre discret d'unites saccharidiques
SG11201503598QA SG11201503598QA (en) 2012-11-13 2013-11-13 Substituted anionic compounds consisting of a backbone consisting of a discrete number of saccharide units
EP13801655.5A EP2920200A1 (fr) 2012-11-13 2013-11-13 Composes anioniques substitues constitues d'un squelette forme d'un nombre discret d'unites saccharidiques
CN201380059092.4A CN104902922B (zh) 2012-11-13 2013-11-13 包含经取代阴离子化合物的速效胰岛素制剂
AU2013346624A AU2013346624B2 (en) 2012-11-13 2013-11-13 Quick-acting insulin formulation including a substituted anionic compound
BR112015010797-4A BR112015010797A2 (pt) 2012-11-13 2013-11-13 compostos aniônicos substituídos, e, composição farmacêutica
AU2013346623A AU2013346623A1 (en) 2012-11-13 2013-11-13 Substituted anionic compounds consisting of a backbone consisting of a discrete number of saccharide units
SG10202112306UA SG10202112306UA (en) 2012-11-13 2013-11-13 Substituted anionic compounds consisting of a backbone consisting of a discrete number of saccharide units
BR112015010799-0A BR112015010799B1 (pt) 2012-11-13 2013-11-13 Composição em solução aquosa, e, formulação farmacêutica
KR1020217001290A KR102367083B1 (ko) 2012-11-13 2013-11-13 치환된 음이온성 화합물을 포함하는 속효성 인슐린 제형
CA2889552A CA2889552C (fr) 2012-11-13 2013-11-13 Formulation a action rapide d'insuline comprenant un compose anionique substitue
EA201590937A EA201590937A1 (ru) 2012-11-13 2013-11-13 Замещенные анионные соединения, имеющие скелет, образованный из небольшого числа сахаридных звеньев
DK13801658.9T DK2919804T3 (en) 2012-11-13 2013-11-13 Rapidly acting insulin formulation comprising a substituted anionic compound
US14/079,516 US9700599B2 (en) 2012-11-13 2013-11-13 Rapid-acting insulin formulation comprising a substituted anionic compound
KR1020207029334A KR20200121381A (ko) 2012-11-13 2013-11-13 개별 갯수의 사카라이드 단위로 이루어지는 백본으로 이루어지는 치환된 음이온성 화합물
CN202010210296.5A CN111494638A (zh) 2012-11-13 2013-11-13 由离散数个糖单元组成的骨架组成的经取代阴离子化合物
EP18154006.3A EP3332810B1 (fr) 2012-11-13 2013-11-13 Formulation à action rapide d'insuline comprenant un composé anionique substitué
SG10201703742SA SG10201703742SA (en) 2012-11-13 2013-11-13 Substituted anionic compounds consisting of a backbone consisting of a discrete number of saccharide units
US14/079,437 US20140187499A1 (en) 2012-11-13 2013-11-13 Substituted anionic compounds consisting of a backbone made up of a discrete number of saccharide units
KR1020157015765A KR20150084056A (ko) 2012-11-13 2013-11-13 개별 갯수의 사카라이드 단위로 이루어지는 백본으로 이루어지는 치환된 음이온성 화합물
PCT/FR2013/052736 WO2014076423A1 (fr) 2012-11-13 2013-11-13 Formulation à action rapide d'insuline comprenant un composé anionique substitué
KR1020207019459A KR102205512B1 (ko) 2012-11-13 2013-11-13 치환된 음이온성 화합물을 포함하는 속효성 인슐린 제형
JP2015542338A JP6322642B2 (ja) 2012-11-13 2013-11-13 置換されたアニオン性化合物を含有する速効型インスリン製剤
MX2015005423A MX2015005423A (es) 2012-11-13 2013-11-13 Compuestos anionicos sustituidos que consisten de un esqueleto formado por un numero discreto de unidades sacaridicas.
CA2889345A CA2889345A1 (fr) 2012-11-13 2013-11-13 Composes anioniques substitues constitues d'un squelette forme d'un nombre discret d'unites saccharidiques
JP2015542337A JP2016505523A (ja) 2012-11-13 2013-11-13 離散数の糖単位から構成される主骨格から成る置換されたアニオン性化合物
CN201711087798.8A CN107952065A (zh) 2012-11-13 2013-11-13 包含经取代阴离子化合物的速效胰岛素制剂
PCT/FR2013/052733 WO2014076422A1 (fr) 2012-11-13 2013-11-13 Composes anioniques substitues constitues d'un squelette forme d'un nombre discret d'unites saccharidiques
ES13801658.9T ES2670969T3 (es) 2012-11-13 2013-11-13 Formulación de acción rápida de insulina que comprende un compuesto aniónico sustituido
PL13801658T PL2919804T3 (pl) 2012-11-13 2013-11-13 Szybko działająca formulacja insuliny zawierająca podstawiony związek anionowy
EP13801658.9A EP2919804B1 (fr) 2012-11-13 2013-11-13 Formulation à action rapide d'insuline comprenant un composé anionique substitué
MX2015005786A MX360107B (es) 2012-11-13 2013-11-13 Formulación de acción rápida de insulina que comprende un compuesto aniónico sustituido.
EA201590944A EA034393B1 (ru) 2012-11-13 2013-11-13 Состав инсулина быстрого действия, содержащий замещенное анионное соединение
CN201380059136.3A CN104903341B (zh) 2012-11-13 2013-11-13 由离散数个糖单元组成的骨架组成的经取代阴离子化合物
KR1020157015793A KR20150082640A (ko) 2012-11-13 2013-11-13 치환된 음이온성 화합물을 포함하는 속효성 인슐린 제형
IL238303A IL238303B (en) 2012-11-13 2015-04-15 Modified anionic compounds containing a skeleton composed of a distinct number of saccharide units
IL238446A IL238446B (en) 2012-11-13 2015-04-26 A fast-acting insulin composition comprising a modified anionic compound
SA515360428A SA515360428B1 (ar) 2012-11-13 2015-05-12 صيغة إنسولين سريعة المفعول تتضمن مركب أنيوني به استبدال
SA515360426A SA515360426B1 (ar) 2012-11-13 2015-05-12 مركبات أنيونية بها استبدال تكوِّن سلسلة رئيسية تتكون من عدد منفصل من وحدات سكاريد
ZA2015/03293A ZA201503293B (en) 2012-11-13 2015-05-12 Quick-acting insulin formulation including a substituted anionic compound
HK16101604.8A HK1213493A1 (zh) 2012-11-13 2016-02-15 包含經取代陰離子化合物的速效胰島素製劑
HK16101679.8A HK1213907A1 (zh) 2012-11-13 2016-02-17 由離散數個糖單元組成的骨架組成的經取代陰離子化合物
US15/410,524 US20170143835A1 (en) 2012-11-13 2017-01-19 Substituted anionic compounds consisting of a backbone made up of a discrete number of saccharide units
US15/609,670 US10583175B2 (en) 2012-11-13 2017-05-31 Rapid-acting insulin formulation comprising a substituted anionic compound
JP2017207105A JP2018021075A (ja) 2012-11-13 2017-10-26 置換されたアニオン性化合物を含有する速効型インスリン製剤
AU2018204764A AU2018204764A1 (en) 2012-11-13 2018-06-29 Substituted anionic compounds consisting of a backbone consisting of a discrete number of saccharide units
AU2018208773A AU2018208773B2 (en) 2012-11-13 2018-07-30 Quick-acting insulin formulation including a substituted anionic compound
HK18111528.8A HK1252137A1 (zh) 2012-11-13 2018-09-07 包含經取代陰離子化合物的速效胰島素製劑
IL261726A IL261726A (en) 2012-11-13 2018-09-12 Modified anionic compounds containing a skeleton composed of a distinct number of saccharide units
JP2019087751A JP7332139B2 (ja) 2012-11-13 2019-05-07 置換されたアニオン性化合物
US16/687,339 US10646551B2 (en) 2012-11-13 2019-11-18 Rapid-acting insulin formulation comprising a substituted anionic compound
US16/848,640 US10881716B2 (en) 2012-11-13 2020-04-14 Rapid-acting insulin formulation comprising a substituted anionic compound
IL274077A IL274077A (en) 2012-11-13 2020-04-20 A fast-acting insulin composition comprising a modified anionic compound
AU2020203078A AU2020203078A1 (en) 2012-11-13 2020-05-10 Substituted anionic compounds consisting of a backbone consisting of a discrete number of saccharide units
ZA2020/03132A ZA202003132B (en) 2012-11-13 2020-05-27 Quick-acting insulin formulation including a substituted anionic compound
US17/096,178 US11324808B2 (en) 2012-11-13 2020-11-12 Rapid-acting insulin formulation comprising a substituted anionic compound
JP2023088245A JP2023099873A (ja) 2012-11-13 2023-05-29 置換されたアニオン性化合物を含有する速効型インスリン製剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1260808A FR2997952B1 (fr) 2012-11-13 2012-11-13 Composes anioniques substitues constitues d'un squelette forme d'un nombre discret d'unites saccharidiques

Publications (2)

Publication Number Publication Date
FR2997952A1 FR2997952A1 (fr) 2014-05-16
FR2997952B1 true FR2997952B1 (fr) 2014-11-21

Family

ID=47666319

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1260808A Active FR2997952B1 (fr) 2012-11-13 2012-11-13 Composes anioniques substitues constitues d'un squelette forme d'un nombre discret d'unites saccharidiques

Country Status (1)

Country Link
FR (1) FR2997952B1 (fr)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2914305B1 (fr) * 2007-03-29 2009-07-03 Proteins & Peptides Man Dextran fonctionnalise par des amino-acides hydrophobes.
FR2934999B1 (fr) * 2008-08-13 2011-07-29 Adocia Polysaccharides fonctionnalises par des derives du tryptophane
FR2936800B1 (fr) * 2008-10-06 2010-12-31 Adocia Polysaccharide comportant des groupes fonctionnels carboxyles substitues par un derive d'alcool hydrophobe
FR2958646B1 (fr) * 2010-04-07 2012-05-18 Adocia Polysaccharides comportant des groupes fonctionnels carboxyles substitues par un derive d'acide hydrophobe.
EP2828297A1 (fr) * 2011-05-10 2015-01-28 Adocia Oligosaccharides fonctionnalisés
US20120295833A1 (en) * 2011-05-10 2012-11-22 Adocia Polysaccharides having an adjustable degree of functionalization
EP2773675B1 (fr) * 2011-11-02 2023-03-01 Adocia Formulation à action rapide d'insuline comprenant un oligosaccharide

Also Published As

Publication number Publication date
FR2997952A1 (fr) 2014-05-16

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