FR2822466B1 - Fraction phenolique riche en phloridzine et son utilisation en tant qu'agent cosmetique, alimentaire ou nutraceutique - Google Patents
Fraction phenolique riche en phloridzine et son utilisation en tant qu'agent cosmetique, alimentaire ou nutraceutiqueInfo
- Publication number
- FR2822466B1 FR2822466B1 FR0103968A FR0103968A FR2822466B1 FR 2822466 B1 FR2822466 B1 FR 2822466B1 FR 0103968 A FR0103968 A FR 0103968A FR 0103968 A FR0103968 A FR 0103968A FR 2822466 B1 FR2822466 B1 FR 2822466B1
- Authority
- FR
- France
- Prior art keywords
- phloridzine
- cosmetic
- food
- solid
- nutraceutical agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000002537 cosmetic Substances 0.000 title 1
- 235000021436 nutraceutical agent Nutrition 0.000 title 1
- 239000007787 solid Substances 0.000 abstract 4
- 239000007788 liquid Substances 0.000 abstract 3
- 150000008442 polyphenolic compounds Chemical class 0.000 abstract 3
- 235000013824 polyphenols Nutrition 0.000 abstract 3
- 241000220225 Malus Species 0.000 abstract 2
- 235000021016 apples Nutrition 0.000 abstract 2
- 238000000605 extraction Methods 0.000 abstract 2
- IOUVKUPGCMBWBT-DARKYYSBSA-N Phloridzin Natural products O[C@H]1[C@@H](O)[C@H](O)[C@H](CO)O[C@H]1OC1=CC(O)=CC(O)=C1C(=O)CCC1=CC=C(O)C=C1 IOUVKUPGCMBWBT-DARKYYSBSA-N 0.000 abstract 1
- 235000004789 Rosa xanthina Nutrition 0.000 abstract 1
- 241000220222 Rosaceae Species 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- IOUVKUPGCMBWBT-UHFFFAOYSA-N phloridzosid Natural products OC1C(O)C(O)C(CO)OC1OC1=CC(O)=CC(O)=C1C(=O)CCC1=CC=C(O)C=C1 IOUVKUPGCMBWBT-UHFFFAOYSA-N 0.000 abstract 1
- IOUVKUPGCMBWBT-QNDFHXLGSA-N phlorizin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC(O)=CC(O)=C1C(=O)CCC1=CC=C(O)C=C1 IOUVKUPGCMBWBT-QNDFHXLGSA-N 0.000 abstract 1
- 235000019139 phlorizin Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
- C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Botany (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Alternative & Traditional Medicine (AREA)
- Food Science & Technology (AREA)
- Obesity (AREA)
- Medical Informatics (AREA)
- Toxicology (AREA)
- Birds (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Cosmetics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0103968A FR2822466B1 (fr) | 2001-03-23 | 2001-03-23 | Fraction phenolique riche en phloridzine et son utilisation en tant qu'agent cosmetique, alimentaire ou nutraceutique |
| DE60206095T DE60206095T2 (de) | 2001-03-23 | 2002-03-19 | Phlorizinreiche Phenolfraktion und ihre Verwendung in der Kosmetik oder als Nahrungsmittel |
| AT02290690T ATE304538T1 (de) | 2001-03-23 | 2002-03-19 | Phlorizinreiche phenolfraktion und ihre verwendung in der kosmetik oder als nahrungsmittel |
| EP02290690A EP1243586B1 (fr) | 2001-03-23 | 2002-03-19 | Fraction phénolique riche en phloridzine et son utilisation en tant qu'agent cosmétique, alimentaire ou nutraceutique. |
| DK02290690T DK1243586T3 (da) | 2001-03-23 | 2002-03-19 | Phloridzinrig phenolfraktion og dens anvendelse i kosmetik eller som næringsmiddel |
| ES02290690T ES2247279T3 (es) | 2001-03-23 | 2002-03-19 | Fraccion fenolica rica en floricina y su utilizacion como agente cosmetico, alimentario o nutraceutico. |
| US10/105,040 US7041322B2 (en) | 2001-03-23 | 2002-03-22 | Phloridzin-rich phenolic fraction and use thereof as a cosmetic, dietary or nutraceutical agent |
| JP2002084030A JP5192110B2 (ja) | 2001-03-23 | 2002-03-25 | フロリジン−リッチなフェノール性画分および化粧剤、食餌療法剤またはニュートラシューティカル剤としてのその使用 |
| US11/282,396 US7427418B2 (en) | 2001-03-23 | 2005-11-18 | Phloridzin-rich phenolic fraction and use thereof as a cosmetic, dietary or nutraceutical agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0103968A FR2822466B1 (fr) | 2001-03-23 | 2001-03-23 | Fraction phenolique riche en phloridzine et son utilisation en tant qu'agent cosmetique, alimentaire ou nutraceutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2822466A1 FR2822466A1 (fr) | 2002-09-27 |
| FR2822466B1 true FR2822466B1 (fr) | 2004-07-02 |
Family
ID=8861487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR0103968A Expired - Fee Related FR2822466B1 (fr) | 2001-03-23 | 2001-03-23 | Fraction phenolique riche en phloridzine et son utilisation en tant qu'agent cosmetique, alimentaire ou nutraceutique |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7041322B2 (enExample) |
| EP (1) | EP1243586B1 (enExample) |
| JP (1) | JP5192110B2 (enExample) |
| AT (1) | ATE304538T1 (enExample) |
| DE (1) | DE60206095T2 (enExample) |
| DK (1) | DK1243586T3 (enExample) |
| ES (1) | ES2247279T3 (enExample) |
| FR (1) | FR2822466B1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2836336B1 (fr) * | 2002-02-26 | 2004-08-27 | Diana Ingredients | Utilisation dans un traitement cosmetique d'une fraction phenolique riche en dihydrochalcones |
| US20040109905A1 (en) * | 2002-09-18 | 2004-06-10 | Debasis Bagchi | Method and composition of anthocyanin-rich berry extracts that prevents or inhibits angiogenesis and helicobacter pylori and acts as a powerful antioxidant that provides various health benefits |
| US9358262B2 (en) * | 2003-03-13 | 2016-06-07 | University Of Ottawa | Use of antioxidant-enriched fermented blueberry extracts in the treatment of diabetes |
| CA2559596A1 (en) | 2003-03-13 | 2004-11-25 | Universite De Moncton (Bureau De Soutien A L'innovation) | Antioxidant producing bacterium and uses thereof |
| RU2233668C1 (ru) * | 2003-05-20 | 2004-08-10 | Федеральное государственное унитарное предприятие "Научно-производственное объединение по медицинским иммунобиологическим препаратам "Микроген" | Способ получения препарата фенольной природы из растительного сырья |
| FR2862303B1 (fr) * | 2003-11-17 | 2006-01-06 | Agronomique Inst Nat Rech | Preparations colorantes hydrosolubles jaunes derivees des dihydrochalcones, leur procede des preparation, et leurs utilisations |
| EP1835884A2 (en) * | 2005-01-14 | 2007-09-26 | Lipo Chemicals Inc | Composition and method for treating hyperpigmented skin |
| US20060172012A1 (en) * | 2005-01-28 | 2006-08-03 | Finley John W | Anti-inflammatory supplement compositions and regimens to reduce cardiovascular disease risks |
| CN100463913C (zh) * | 2005-03-11 | 2009-02-25 | 天津市尖峰天然产物研究开发有限公司 | 从蔷薇科植物的皮根枝叶及榨汁废料中提取根皮苷的工艺 |
| JP5067916B2 (ja) * | 2005-10-05 | 2012-11-07 | 丸善製薬株式会社 | 皮膚化粧料及び頭髪化粧料 |
| JP2007326799A (ja) * | 2006-06-07 | 2007-12-20 | Kao Corp | 活性酸素消去酵素発現促進剤 |
| US20070298013A1 (en) * | 2006-06-23 | 2007-12-27 | Altman Jay A | Animal Nutritional Supplement and Method |
| FR2906145B1 (fr) * | 2006-09-25 | 2008-12-12 | Cooperative Les Celliers Assoc | Procede d'extraction de phloridzine a partir de pepins de pomme |
| NZ564691A (en) * | 2007-12-21 | 2010-03-26 | Nz Inst Plant & Food Res Ltd | Glycosyltransferases, polynucleotides encoding these and methods of use |
| FR2928263B1 (fr) * | 2008-03-07 | 2010-06-18 | Oreal | Procede de traitement cosmetique a base de polyphenols de fruits ou de legumes |
| US20090300998A1 (en) * | 2008-06-03 | 2009-12-10 | Ablett Richard F | Modular portable micro-factory system |
| EP2299852B1 (en) * | 2008-06-16 | 2015-08-05 | Eckes-Granini Group GmbH | Beverage composition |
| FR2935096B1 (fr) * | 2008-08-21 | 2010-12-10 | Cooperative Agricole D Elle Et Vire | Compositions riches en acide chlorogenique, leur procede d'obtention et leur utilisation |
| AU2009319881C1 (en) * | 2008-11-26 | 2015-12-24 | Perio Sciences, Llc | Antioxidant compositions for soft oral tissue and methods of formulation and use thereof |
| WO2012104145A1 (en) | 2011-01-31 | 2012-08-09 | Dsm Ip Assets B.V. | Dihydrochalcone purification process |
| CA2849910A1 (en) | 2011-09-30 | 2013-04-04 | Perio Sciences, Llc | Antioxidant compositions for treatment of inflammation or oxidative damage |
| EP2596704A1 (en) * | 2011-11-28 | 2013-05-29 | Nestec S.A. | Increasing the bioavailability of hydroxycinnamic acids |
| KR101417310B1 (ko) | 2012-08-06 | 2014-07-08 | 제주대학교 산학협력단 | 아그배나무 가지 추출물, 분획물 또는 화합물을 포함하는 화장료 조성물 |
| EP2944311A1 (de) * | 2014-05-16 | 2015-11-18 | BioActive Food GmbH | Kombination von biologisch aktiven Substanzen zur Behandlung von hyperglykämischen Erkrankungen |
| US10616382B2 (en) * | 2016-09-02 | 2020-04-07 | Accedian Networks Inc. | Efficient capture and streaming of data packets |
| JP2018150276A (ja) * | 2017-03-13 | 2018-09-27 | アサヒグループホールディングス株式会社 | フロレチン配糖体類の精製方法 |
| CN108634309B (zh) * | 2018-04-13 | 2021-10-08 | 陕西师范大学 | 野生水麻叶提取物及其新用途 |
| FR3158225A1 (fr) | 2024-01-16 | 2025-07-18 | Laboratoire Clemascience | Compositions nutraceutiques et leur utilisation pour induire une perte de poids corporel et/ou une réduction de l’accumulation de graisse. |
| CN119591440B (zh) * | 2024-11-13 | 2025-11-21 | 华中农业大学 | 一种钼调控的增效物质根皮苷在促进作物生长及活化土壤磷中的应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1427100A (fr) | 1964-12-14 | 1966-02-04 | Ile De Rech Pharma Et Therapeu | Procédé pour l'obtention d'hydroxyflavanne-3-4-diols |
| FR2092743A1 (en) | 1970-06-15 | 1972-01-28 | Aquitaine Invest Pharma | Complete extraction of total flavanol gomers from plats -peripheral - venous activity |
| GB1541469A (en) | 1976-12-01 | 1979-02-28 | Inverni Della Beffa Spa | Method of obtaining flavonolic oligomers |
| US5110801A (en) * | 1984-08-13 | 1992-05-05 | Leveen Harry H | Treatment of acne |
| US4698360B1 (en) | 1985-04-09 | 1997-11-04 | D Investigations Pharmacologiq | Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenger effect and use thereof |
| FR2611140B1 (fr) | 1987-02-20 | 1991-02-22 | Lamaison Jean Louis | Procede d'obtention de principes tanniques d'origine vegetale, composition cosmetologique et composition pharmaceutique contenant le principe tannique purifie obtenu selon le procede |
| IT1219732B (it) | 1988-06-28 | 1990-05-24 | Tecnofarmaci Spa | Frazioni oligomeriche procianidoliche,loro procedimento di preparazione e composizioni farmaceutiche che le contengono |
| FR2643073B1 (fr) | 1989-02-15 | 1991-08-16 | Expansion Rech Phytochimie | Procede de preparation d'extraits polyphenoliques de type flavane-3-ol purifies et extraits obtenus |
| JPH05294818A (ja) * | 1992-04-17 | 1993-11-09 | H Lhevinne Harry | にきびの治療に有効な薬剤およびにきびの治療方法並びに上記薬剤を含有する化粧品組成物 |
| JP3521155B2 (ja) * | 1993-12-06 | 2004-04-19 | ニッカウヰスキー株式会社 | 果実ポリフェノールの製造方法 |
| CA2128293C (en) * | 1993-12-06 | 2002-09-03 | Masayuki Tanabe | Fruit polyphenols and medicinal compositions containing them |
| DE4444238A1 (de) * | 1994-12-13 | 1996-06-20 | Beiersdorf Ag | Kosmetische oder dermatologische Wirkstoffkombinationen aus Zimtsäurederivaten und Flavonglycosiden |
| JPH09175982A (ja) * | 1995-12-28 | 1997-07-08 | Nikka Uisukii Kk | 化粧品 |
| AU5755200A (en) * | 1999-08-27 | 2001-03-26 | Joel R.L. Ehrenkranz | Method of using dihydrochalcone derivatives to block glucose transfer |
| FR2799121B1 (fr) * | 1999-10-01 | 2004-02-13 | Fabre Pierre Dermo Cosmetique | Extraits de branches de pommiers utiles en dermocosmetologie et leur procede de preparation |
| US6509054B1 (en) * | 2000-05-05 | 2003-01-21 | American Fruits And Flavors | Food additives having enlarged concentration of phenolics extracted from fruits, and process of obtaining the same |
| JP2001348336A (ja) * | 2000-06-07 | 2001-12-18 | Fancl Corp | 紫外線障害抑制用組成物 |
-
2001
- 2001-03-23 FR FR0103968A patent/FR2822466B1/fr not_active Expired - Fee Related
-
2002
- 2002-03-19 EP EP02290690A patent/EP1243586B1/fr not_active Expired - Lifetime
- 2002-03-19 ES ES02290690T patent/ES2247279T3/es not_active Expired - Lifetime
- 2002-03-19 DE DE60206095T patent/DE60206095T2/de not_active Expired - Lifetime
- 2002-03-19 AT AT02290690T patent/ATE304538T1/de active
- 2002-03-19 DK DK02290690T patent/DK1243586T3/da active
- 2002-03-22 US US10/105,040 patent/US7041322B2/en not_active Expired - Lifetime
- 2002-03-25 JP JP2002084030A patent/JP5192110B2/ja not_active Expired - Fee Related
-
2005
- 2005-11-18 US US11/282,396 patent/US7427418B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7427418B2 (en) | 2008-09-23 |
| JP5192110B2 (ja) | 2013-05-08 |
| EP1243586B1 (fr) | 2005-09-14 |
| US20030003120A1 (en) | 2003-01-02 |
| ATE304538T1 (de) | 2005-09-15 |
| US20060073223A1 (en) | 2006-04-06 |
| EP1243586A1 (fr) | 2002-09-25 |
| JP2002322067A (ja) | 2002-11-08 |
| US7041322B2 (en) | 2006-05-09 |
| DK1243586T3 (da) | 2005-11-21 |
| FR2822466A1 (fr) | 2002-09-27 |
| ES2247279T3 (es) | 2006-03-01 |
| DE60206095T2 (de) | 2006-06-29 |
| DE60206095D1 (de) | 2005-10-20 |
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