FR2775435B1 - Nanoparticules comprenant au moins un polymere et au moins un compose apte a complexer un ou plusieurs principes actifs - Google Patents

Nanoparticules comprenant au moins un polymere et au moins un compose apte a complexer un ou plusieurs principes actifs

Info

Publication number
FR2775435B1
FR2775435B1 FR9802429A FR9802429A FR2775435B1 FR 2775435 B1 FR2775435 B1 FR 2775435B1 FR 9802429 A FR9802429 A FR 9802429A FR 9802429 A FR9802429 A FR 9802429A FR 2775435 B1 FR2775435 B1 FR 2775435B1
Authority
FR
France
Prior art keywords
nanoparticles
polymer
complexing
active ingredients
compound capable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9802429A
Other languages
English (en)
French (fr)
Other versions
FR2775435A1 (fr
Inventor
Da Silveira Airton Monza
Gilles Ponchel
Dominique Duchene
Patrick Couvreur
Francis Puisieux
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioalliance Pharma SA
Original Assignee
Bioalliance Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9802429A priority Critical patent/FR2775435B1/fr
Application filed by Bioalliance Pharma SA filed Critical Bioalliance Pharma SA
Priority to PCT/FR1999/000418 priority patent/WO1999043359A1/fr
Priority to JP2000533154A priority patent/JP4651192B2/ja
Priority to AU26287/99A priority patent/AU753573B2/en
Priority to CA002320928A priority patent/CA2320928C/fr
Priority to DK99906300T priority patent/DK1056477T3/da
Priority to ES99906300T priority patent/ES2255246T3/es
Priority to DE69928776T priority patent/DE69928776T2/de
Priority to EP99906300A priority patent/EP1056477B1/fr
Priority to AT99906300T priority patent/ATE311906T1/de
Priority to IL13788299A priority patent/IL137882A0/xx
Publication of FR2775435A1 publication Critical patent/FR2775435A1/fr
Application granted granted Critical
Publication of FR2775435B1 publication Critical patent/FR2775435B1/fr
Priority to IL137882A priority patent/IL137882A/en
Priority to US09/648,304 priority patent/US6881421B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FR9802429A 1998-02-27 1998-02-27 Nanoparticules comprenant au moins un polymere et au moins un compose apte a complexer un ou plusieurs principes actifs Expired - Fee Related FR2775435B1 (fr)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR9802429A FR2775435B1 (fr) 1998-02-27 1998-02-27 Nanoparticules comprenant au moins un polymere et au moins un compose apte a complexer un ou plusieurs principes actifs
IL13788299A IL137882A0 (en) 1998-02-27 1999-02-24 Nanoparticles comprising at least one polymer and at least one compound able to complex one or more active ingredients
AU26287/99A AU753573B2 (en) 1998-02-27 1999-02-24 Nanoparticles comprising polyisobutylcyanoacrylate and cyclodextrins
CA002320928A CA2320928C (fr) 1998-02-27 1999-02-24 Nanoparticules comprenant un poly(cyanoacrylate d'alkyl) et un oligosaccharide cyclique
DK99906300T DK1056477T3 (da) 1998-02-27 1999-02-24 Naopartikler omfattende polyisobutylcyanoacrylat og cyclodextriner
ES99906300T ES2255246T3 (es) 1998-02-27 1999-02-24 Nanoparticulas que comprenden poli(cianoacrilato de isobutilo) y ciclodextrinas.
PCT/FR1999/000418 WO1999043359A1 (fr) 1998-02-27 1999-02-24 Nanoparticules comprenant polyisobutylcyanoacrylate et cyclodextrines
EP99906300A EP1056477B1 (fr) 1998-02-27 1999-02-24 Nanoparticules comprenant polyisobutylcyanoacrylate et cyclodextrines
AT99906300T ATE311906T1 (de) 1998-02-27 1999-02-24 Nanopartikel die polyisobutylcyanoacrylate und cyclodextrine enthalten
JP2000533154A JP4651192B2 (ja) 1998-02-27 1999-02-24 少なくとも一つの重合体および一つ又は複数の有効成分と複合体を形成できる少なくとも一つの化合物から成るナノ粒子およびその製造方法
DE69928776T DE69928776T2 (de) 1998-02-27 1999-02-24 Nanopartikel die polyisobutylcyanoacrylate und cyclodextrine enthalten
IL137882A IL137882A (en) 1998-02-27 2000-08-15 Nanoparticles comprising at least one polymer and at least one compound able to complex one or more active ingredients
US09/648,304 US6881421B1 (en) 1998-02-27 2000-08-25 Nanoparticles comprising at least one polymer and at least one compound able to complex one or more active ingredients

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9802429A FR2775435B1 (fr) 1998-02-27 1998-02-27 Nanoparticules comprenant au moins un polymere et au moins un compose apte a complexer un ou plusieurs principes actifs

Publications (2)

Publication Number Publication Date
FR2775435A1 FR2775435A1 (fr) 1999-09-03
FR2775435B1 true FR2775435B1 (fr) 2000-05-26

Family

ID=9523473

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9802429A Expired - Fee Related FR2775435B1 (fr) 1998-02-27 1998-02-27 Nanoparticules comprenant au moins un polymere et au moins un compose apte a complexer un ou plusieurs principes actifs

Country Status (12)

Country Link
US (1) US6881421B1 (https=)
EP (1) EP1056477B1 (https=)
JP (1) JP4651192B2 (https=)
AT (1) ATE311906T1 (https=)
AU (1) AU753573B2 (https=)
CA (1) CA2320928C (https=)
DE (1) DE69928776T2 (https=)
DK (1) DK1056477T3 (https=)
ES (1) ES2255246T3 (https=)
FR (1) FR2775435B1 (https=)
IL (2) IL137882A0 (https=)
WO (1) WO1999043359A1 (https=)

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Also Published As

Publication number Publication date
AU2628799A (en) 1999-09-15
US6881421B1 (en) 2005-04-19
FR2775435A1 (fr) 1999-09-03
JP2002504526A (ja) 2002-02-12
WO1999043359A1 (fr) 1999-09-02
EP1056477A1 (fr) 2000-12-06
CA2320928C (fr) 2009-12-15
IL137882A (en) 2006-12-31
DE69928776T2 (de) 2006-09-07
DE69928776D1 (de) 2006-01-12
IL137882A0 (en) 2001-10-31
DK1056477T3 (da) 2006-04-18
JP4651192B2 (ja) 2011-03-16
AU753573B2 (en) 2002-10-24
ATE311906T1 (de) 2005-12-15
ES2255246T3 (es) 2006-06-16
CA2320928A1 (fr) 1999-09-02
EP1056477B1 (fr) 2005-12-07

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