FR2645153B1 - Derives de la thieno-triazolo-diazepine ainsi que leur procede de preparation - Google Patents

Derives de la thieno-triazolo-diazepine ainsi que leur procede de preparation

Info

Publication number
FR2645153B1
FR2645153B1 FR909004156A FR9004156A FR2645153B1 FR 2645153 B1 FR2645153 B1 FR 2645153B1 FR 909004156 A FR909004156 A FR 909004156A FR 9004156 A FR9004156 A FR 9004156A FR 2645153 B1 FR2645153 B1 FR 2645153B1
Authority
FR
France
Prior art keywords
thieno
triazolo
preparation process
diazepine derivatives
diazepine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR909004156A
Other languages
English (en)
French (fr)
Other versions
FR2645153A1 (fr
Inventor
Pierre Braquet
Jean-Pierre Laurent
Andre Esanu
Alain Rolland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of FR2645153A1 publication Critical patent/FR2645153A1/fr
Application granted granted Critical
Publication of FR2645153B1 publication Critical patent/FR2645153B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR909004156A 1989-03-31 1990-04-02 Derives de la thieno-triazolo-diazepine ainsi que leur procede de preparation Expired - Lifetime FR2645153B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898907256A GB8907256D0 (en) 1989-03-31 1989-03-31 New derivatives of hetrazepine as anti-asthmatic anti-allergic and gastro-intestinal protectors

Publications (2)

Publication Number Publication Date
FR2645153A1 FR2645153A1 (fr) 1990-10-05
FR2645153B1 true FR2645153B1 (fr) 1992-04-17

Family

ID=10654231

Family Applications (2)

Application Number Title Priority Date Filing Date
FR909004156A Expired - Lifetime FR2645153B1 (fr) 1989-03-31 1990-04-02 Derives de la thieno-triazolo-diazepine ainsi que leur procede de preparation
FR909004155A Expired - Lifetime FR2645022B1 (fr) 1989-03-31 1990-04-02 Compositions therapeutiques a base de derives de la thieno-triazolo-diazepine

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR909004155A Expired - Lifetime FR2645022B1 (fr) 1989-03-31 1990-04-02 Compositions therapeutiques a base de derives de la thieno-triazolo-diazepine

Country Status (30)

Country Link
US (1) US5492906A (cg-RX-API-DMAC7.html)
JP (1) JPH07103127B2 (cg-RX-API-DMAC7.html)
KR (1) KR900014396A (cg-RX-API-DMAC7.html)
AT (1) AT394561B (cg-RX-API-DMAC7.html)
AU (1) AU622007B2 (cg-RX-API-DMAC7.html)
BE (1) BE1003699A3 (cg-RX-API-DMAC7.html)
CA (1) CA2013518C (cg-RX-API-DMAC7.html)
CH (1) CH680365A5 (cg-RX-API-DMAC7.html)
DE (1) DE4010316C2 (cg-RX-API-DMAC7.html)
DK (1) DK80890A (cg-RX-API-DMAC7.html)
ES (1) ES2019243A6 (cg-RX-API-DMAC7.html)
FI (1) FI95036C (cg-RX-API-DMAC7.html)
FR (2) FR2645153B1 (cg-RX-API-DMAC7.html)
GB (2) GB8907256D0 (cg-RX-API-DMAC7.html)
GR (1) GR1000394B (cg-RX-API-DMAC7.html)
HK (1) HK95192A (cg-RX-API-DMAC7.html)
IE (1) IE64564B1 (cg-RX-API-DMAC7.html)
IN (1) IN174015B (cg-RX-API-DMAC7.html)
IT (1) IT1240350B (cg-RX-API-DMAC7.html)
LU (1) LU87710A1 (cg-RX-API-DMAC7.html)
MA (1) MA21790A1 (cg-RX-API-DMAC7.html)
MY (1) MY105538A (cg-RX-API-DMAC7.html)
NL (1) NL194827C (cg-RX-API-DMAC7.html)
NO (1) NO173784C (cg-RX-API-DMAC7.html)
NZ (1) NZ233011A (cg-RX-API-DMAC7.html)
OA (1) OA09442A (cg-RX-API-DMAC7.html)
PT (1) PT93629B (cg-RX-API-DMAC7.html)
SE (1) SE505417C2 (cg-RX-API-DMAC7.html)
TN (1) TNSN90042A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA901765B (cg-RX-API-DMAC7.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
US5221671A (en) * 1988-10-31 1993-06-22 Eisai Co., Ltd. Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
US5382579A (en) * 1988-10-31 1995-01-17 Eisai Co., Ltd. Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
US5304553A (en) * 1988-10-31 1994-04-19 Eisai Co., Ltd. 1,4-diazepine derivative and its pharmaceutical use
DE4027470A1 (de) * 1990-08-30 1992-03-05 Boehringer Ingelheim Kg Neue hetrazepinoide amide
ES2061406B1 (es) * 1993-05-07 1995-06-01 Uriach & Cia Sa J Nuevos derivados de la 2-(quinolina) con actividad farmacologica.
FI101989B (fi) * 1996-11-22 1998-09-30 Stora Enso Oyj Menetelmät neste- ja kaasutiiviin pakkauskartongin sekä pakkauksen val mistamiseksi sekä menetelmien mukaisesti valmistetut tuotteet
WO1998058930A1 (en) * 1997-06-25 1998-12-30 Nikken Chemicals Co., Ltd. Triazolo-1,4-diazepine compounds and medicinal composition containing the same
FR2779652B1 (fr) * 1998-06-15 2001-06-08 Sod Conseils Rech Applic Utilisation de diazepines pour la preparation de medicaments destines a traiter les etats pathologiques ou les maladies dans lesquels un des recepteurs de la somatostatine est implique
AU2001255708A1 (en) * 2000-04-28 2001-11-12 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Synthesis and use of thienotriazolodiazepines
RS20050890A (sr) * 2003-05-30 2007-12-31 Ranbaxy Laboratories Limited, Supstituisani pirol derivati
WO2007054896A1 (en) * 2005-11-08 2007-05-18 Ranbaxy Laboratories Limited Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
CL2007000667A1 (es) * 2006-03-14 2008-03-14 Ranbaxi Lab Ltd Composicion farmaceutica que comprende al acido 7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino)carbonil]pirrol-1-il]-3,5-dihidroxi-heptanoico o una sal y al menos un agente estabilizante; procedimiento de preparacion, util en e
MX2009000439A (es) * 2006-07-14 2009-02-04 Ranbaxy Lab Ltd Formas polimorficas de un inhibidor de hmg-coa reductasa y usos de las mismas.
KR101675984B1 (ko) 2015-02-23 2016-11-14 한양대학교 에리카산학협력단 티에노디아제핀 유도체 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 포함하는 약학적 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
WO1988009792A1 (fr) * 1987-06-08 1988-12-15 Yoshitomi Pharmaceutical Industries, Ltd. Composes de thienotriazolodiazepine a substitution ether et leur utilisation en medecine
FI95708C (fi) * 1988-10-31 1996-03-11 Eisai Co Ltd Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
NL9000627A (nl) * 1990-03-29 1991-10-16 Scras Werkwijze ter bereiding van nieuwe thienotriazolo-diazepines.

Also Published As

Publication number Publication date
GB2229723B (en) 1992-07-01
IN174015B (cg-RX-API-DMAC7.html) 1994-08-27
NO173784C (no) 1994-02-02
OA09442A (fr) 1992-10-15
IT1240350B (it) 1993-12-07
AU5242590A (en) 1990-11-01
CH680365A5 (cg-RX-API-DMAC7.html) 1992-08-14
IE900806L (en) 1990-09-30
JPH02289582A (ja) 1990-11-29
CA2013518A1 (en) 1990-09-30
FR2645153A1 (fr) 1990-10-05
NZ233011A (en) 1991-02-26
IE64564B1 (en) 1996-08-23
PT93629A (pt) 1990-11-20
LU87710A1 (fr) 1990-07-24
NO901070D0 (no) 1990-03-07
GR900100165A (en) 1990-07-31
HK95192A (en) 1992-12-04
FI95036C (fi) 1995-12-11
SE505417C2 (sv) 1997-08-25
GR1000394B (el) 1992-06-30
ATA56790A (de) 1991-10-15
SE9000871D0 (sv) 1990-03-12
FI95036B (fi) 1995-08-31
DK80890A (da) 1990-10-01
IT9019884A0 (it) 1990-03-30
AT394561B (de) 1992-05-11
AU622007B2 (en) 1992-03-26
NL9000626A (nl) 1990-10-16
GB9007000D0 (en) 1990-05-30
ZA901765B (en) 1990-12-28
NL194827C (nl) 2003-04-03
NO901070L (no) 1990-10-01
BE1003699A3 (fr) 1992-05-26
SE9000871L (sv) 1990-10-01
FI901605A0 (fi) 1990-03-30
IT9019884A1 (it) 1991-09-30
ES2019243A6 (es) 1991-06-01
MY105538A (en) 1994-10-31
US5492906A (en) 1996-02-20
GB2229723A (en) 1990-10-03
CA2013518C (en) 2004-02-24
FR2645022A1 (fr) 1990-10-05
DK80890D0 (da) 1990-03-30
TNSN90042A1 (fr) 1991-03-05
JPH07103127B2 (ja) 1995-11-08
DE4010316A1 (de) 1990-10-04
NL194827B (nl) 2002-12-02
MA21790A1 (fr) 1990-10-01
DE4010316C2 (de) 2003-05-28
FR2645022B1 (fr) 1992-04-17
KR900014396A (ko) 1990-10-23
PT93629B (pt) 1996-07-31
GB8907256D0 (en) 1989-05-17
NO173784B (no) 1993-10-25

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20091231