FR2539742B1 - Derives amines de la pyridazine substitues en position 6 par un heterocycle ou un alicycle, lesdits derives etant actifs sur le systeme nerveux central - Google Patents
Derives amines de la pyridazine substitues en position 6 par un heterocycle ou un alicycle, lesdits derives etant actifs sur le systeme nerveux centralInfo
- Publication number
- FR2539742B1 FR2539742B1 FR8301029A FR8301029A FR2539742B1 FR 2539742 B1 FR2539742 B1 FR 2539742B1 FR 8301029 A FR8301029 A FR 8301029A FR 8301029 A FR8301029 A FR 8301029A FR 2539742 B1 FR2539742 B1 FR 2539742B1
- Authority
- FR
- France
- Prior art keywords
- derivatives
- nervous system
- central nervous
- alicycle
- heterocycle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000003169 central nervous system Anatomy 0.000 title abstract 2
- 150000001412 amines Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000001541 3-thienyl group Chemical group S1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000004892 pyridazines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (24)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8301029A FR2539742B1 (fr) | 1983-01-24 | 1983-01-24 | Derives amines de la pyridazine substitues en position 6 par un heterocycle ou un alicycle, lesdits derives etant actifs sur le systeme nerveux central |
| DE8484400102T DE3464491D1 (en) | 1983-01-24 | 1984-01-18 | Amino derivatives of substituted pyridazines, process for their preparation and medicines containing them |
| US06/571,698 US4524070A (en) | 1983-01-24 | 1984-01-18 | Aminated derivatives of pyridazine substituted in 6 position by a heterocycle or an alicycle and compositions, said derivatives being active on the central nervous system |
| CA000445483A CA1218063A (en) | 1983-01-24 | 1984-01-18 | Process for obtaining aminated derivatives of pyridazine substituted in 6 position by a heterocycle or an alicycle |
| AT84400102T ATE28077T1 (de) | 1983-01-24 | 1984-01-18 | Aminoderivate von in stellung 6 durch ein heterocyclisch oder ein alicyclisch substituiertes pyridazin, verfahren zu deren herstellung und heilmittel die sie enthalten. |
| EP84400102A EP0117171B1 (fr) | 1983-01-24 | 1984-01-18 | Dérivés aminés de la pyridazine substitués en position 6 par un hétérocycle ou un alicycle, procédé d'obtention et médicaments les contenant |
| ES529007A ES529007A0 (es) | 1983-01-24 | 1984-01-19 | Procedimiento para la fabricacion de derivados aminados de la piridazina substituidos en posicion 6 por un heterociclo o un aliciclo, activos sobre el sistema nervioso central. |
| NZ206907A NZ206907A (en) | 1983-01-24 | 1984-01-20 | Morpholinoethylamino pyridazine derivatives and pharmaceutical compositions thereof |
| PT77982A PT77982B (fr) | 1983-01-24 | 1984-01-20 | Procede pour l'obtention de derives amines de la pyridazine substitues en position 6 actifs sur le systeme nerveum central |
| FI840268A FI840268A7 (fi) | 1983-01-24 | 1984-01-23 | Foerfarande foer erhaollande av aminerade derivat av pyridazin, vilka aer substituerade i 6-positionen med en heterocyklisk eller en alicyklisk ring. |
| NO840244A NO840244L (no) | 1983-01-24 | 1984-01-23 | Fremgangsmaate for fremstilling av aminerte derivater av pyridazin. |
| IL70757A IL70757A (en) | 1983-01-24 | 1984-01-23 | 3-morpholinoethylamino-6-cyclohexyl-or-thienylpyridazine derivatives,their preparation and pharmaceutical compositions containing them |
| ZA84501A ZA84501B (en) | 1983-01-24 | 1984-01-23 | Aminated derivatives of pyridazine substituted in 6 position by a heterocycle or an alicycle |
| KR1019840000274A KR910000641B1 (ko) | 1983-01-24 | 1984-01-23 | 복소환 또는 치환에 의해 6위치에 치환된 아미노화 피리다진 유도체의 제조방법 |
| IE840150A IE840150L (en) | 1983-01-24 | 1984-01-23 | Aminated pyridazine antidepressants. |
| DD84259545A DD238793A5 (de) | 1983-01-24 | 1984-01-23 | Verfahren zur herstellung von amin-derivaten des pyrazins |
| GR73585A GR81717B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1983-01-24 | 1984-01-23 | |
| SU843694357A SU1189345A3 (ru) | 1983-01-24 | 1984-01-23 | Способ получени аминопроизводных пиридазина или их солей с кислотами |
| YU00123/84A YU12384A (en) | 1983-01-24 | 1984-01-24 | Process for making amino derivatives of piridazine, substituted in position 6 with heterocyclic or acyclic compound with effect on the central neurosystem |
| JP59010903A JPS59139367A (ja) | 1983-01-24 | 1984-01-24 | ピリダジン誘導体，その製造方法，及び該化合物を含有する医薬 |
| CS84530A CS241539B2 (en) | 1983-01-24 | 1984-01-24 | Method of pyridazine's amine derivatives production |
| DK31584A DK31584A (da) | 1983-01-24 | 1984-01-24 | Aminerede derivater af pyridazin, som i 6-stillingen er substitueret med en heterocyklisk eller en alicyklisk gruppe, fremgangsmaade til fremstilling heraf og laegemidler med indhold heraf |
| HU84294A HU192390B (en) | 1983-01-24 | 1984-01-24 | Process for producing aminated derivatives of 6-heterocyclic or 6-alicyclic-piridazine and pharmaceutical compositions containing them |
| AU23727/84A AU560542B2 (en) | 1983-01-24 | 1984-01-24 | Pyridazine derivatives which have c.n.s. activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8301029A FR2539742B1 (fr) | 1983-01-24 | 1983-01-24 | Derives amines de la pyridazine substitues en position 6 par un heterocycle ou un alicycle, lesdits derives etant actifs sur le systeme nerveux central |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2539742A1 FR2539742A1 (fr) | 1984-07-27 |
| FR2539742B1 true FR2539742B1 (fr) | 1986-09-05 |
Family
ID=9285222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8301029A Expired FR2539742B1 (fr) | 1983-01-24 | 1983-01-24 | Derives amines de la pyridazine substitues en position 6 par un heterocycle ou un alicycle, lesdits derives etant actifs sur le systeme nerveux central |
Country Status (24)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0377606B1 (de) * | 1987-08-19 | 1992-11-25 | RWE-Entsorgung Aktiengesellschaft | Verfahren zur reinigung und regenerierung von altölen |
| FR2665442B1 (fr) * | 1990-07-31 | 1992-12-04 | Sanofi Sa | Derives d'alkyl-6 pyridazine, procede de preparation et compositions pharmaceutiques en contenant. |
| US5631255A (en) * | 1989-02-07 | 1997-05-20 | Sanofi | Pyridazine derivatives |
| PT93060B (pt) | 1989-02-07 | 1995-12-29 | Sanofi Sa | Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem |
| US5461053A (en) * | 1989-02-07 | 1995-10-24 | Sanofi | Pyridazine derivatives |
| CA2564996A1 (en) * | 2004-05-08 | 2006-01-12 | Taeyoung Yoon | 3-aryl-5,6-disubstituted pyridazines |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1292443A (en) * | 1968-11-01 | 1972-10-11 | Ct D Etudes Experimentales Et | New pyridazine derivatives and process for their preparation |
| GB1345880A (en) * | 1971-06-18 | 1974-02-06 | Cepbepe | Pyridazine derivatives |
-
1983
- 1983-01-24 FR FR8301029A patent/FR2539742B1/fr not_active Expired
-
1984
- 1984-01-18 CA CA000445483A patent/CA1218063A/en not_active Expired
- 1984-01-18 AT AT84400102T patent/ATE28077T1/de active
- 1984-01-18 DE DE8484400102T patent/DE3464491D1/de not_active Expired
- 1984-01-18 EP EP84400102A patent/EP0117171B1/fr not_active Expired
- 1984-01-18 US US06/571,698 patent/US4524070A/en not_active Expired - Fee Related
- 1984-01-19 ES ES529007A patent/ES529007A0/es active Granted
- 1984-01-20 NZ NZ206907A patent/NZ206907A/en unknown
- 1984-01-20 PT PT77982A patent/PT77982B/pt not_active IP Right Cessation
- 1984-01-23 SU SU843694357A patent/SU1189345A3/ru active
- 1984-01-23 IL IL70757A patent/IL70757A/xx unknown
- 1984-01-23 FI FI840268A patent/FI840268A7/fi not_active Application Discontinuation
- 1984-01-23 ZA ZA84501A patent/ZA84501B/xx unknown
- 1984-01-23 KR KR1019840000274A patent/KR910000641B1/ko not_active Expired
- 1984-01-23 IE IE840150A patent/IE840150L/xx unknown
- 1984-01-23 NO NO840244A patent/NO840244L/no unknown
- 1984-01-23 DD DD84259545A patent/DD238793A5/de unknown
- 1984-01-23 GR GR73585A patent/GR81717B/el unknown
- 1984-01-24 JP JP59010903A patent/JPS59139367A/ja active Pending
- 1984-01-24 HU HU84294A patent/HU192390B/hu unknown
- 1984-01-24 DK DK31584A patent/DK31584A/da unknown
- 1984-01-24 CS CS84530A patent/CS241539B2/cs unknown
- 1984-01-24 AU AU23727/84A patent/AU560542B2/en not_active Ceased
- 1984-01-24 YU YU00123/84A patent/YU12384A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK31584D0 (da) | 1984-01-24 |
| US4524070A (en) | 1985-06-18 |
| NZ206907A (en) | 1987-03-31 |
| HU192390B (en) | 1987-06-29 |
| DE3464491D1 (en) | 1987-08-06 |
| PT77982A (fr) | 1984-02-01 |
| ZA84501B (en) | 1984-09-26 |
| IE840150L (en) | 1984-07-24 |
| AU2372784A (en) | 1984-07-26 |
| CS241539B2 (en) | 1986-03-13 |
| DK31584A (da) | 1984-07-25 |
| CS53084A2 (en) | 1985-07-16 |
| KR840007409A (ko) | 1984-12-07 |
| KR910000641B1 (ko) | 1991-01-31 |
| ES8407043A1 (es) | 1984-09-01 |
| FR2539742A1 (fr) | 1984-07-27 |
| EP0117171B1 (fr) | 1987-07-01 |
| FI840268A0 (fi) | 1984-01-23 |
| ES529007A0 (es) | 1984-09-01 |
| EP0117171A1 (fr) | 1984-08-29 |
| CA1218063A (en) | 1987-02-17 |
| FI840268A7 (fi) | 1984-07-25 |
| JPS59139367A (ja) | 1984-08-10 |
| IL70757A (en) | 1986-12-31 |
| YU12384A (en) | 1986-10-31 |
| IL70757A0 (en) | 1984-04-30 |
| ATE28077T1 (de) | 1987-07-15 |
| AU560542B2 (en) | 1987-04-09 |
| NO840244L (no) | 1984-07-25 |
| SU1189345A3 (ru) | 1985-10-30 |
| PT77982B (fr) | 1986-04-10 |
| DD238793A5 (de) | 1986-09-03 |
| GR81717B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-12-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |