FR2523153A1 - Obtention de mutants de clostridium acetobutylicum a haute productivite de butanol et d'acetone, mutants obtenus et utilisation de ces mutants pour la production conjointe de butanol et d'acetone - Google Patents

Obtention de mutants de clostridium acetobutylicum a haute productivite de butanol et d'acetone, mutants obtenus et utilisation de ces mutants pour la production conjointe de butanol et d'acetone Download PDF

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Publication number
FR2523153A1
FR2523153A1 FR8203980A FR8203980A FR2523153A1 FR 2523153 A1 FR2523153 A1 FR 2523153A1 FR 8203980 A FR8203980 A FR 8203980A FR 8203980 A FR8203980 A FR 8203980A FR 2523153 A1 FR2523153 A1 FR 2523153A1
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Prior art keywords
butanol
mutants
mutant
strain
acetone
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Granted
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FR8203980A
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English (en)
French (fr)
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FR2523153B1 (enExample
Inventor
Monique Hermann
Francoise Fayolle
Remy Marchal
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IFP Energies Nouvelles IFPEN
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IFP Energies Nouvelles IFPEN
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Priority to FR8203980A priority Critical patent/FR2523153A1/fr
Priority to EP83400339A priority patent/EP0088656B1/fr
Priority to DE8383400339T priority patent/DE3361193D1/de
Priority to AT83400339T priority patent/ATE16509T1/de
Priority to ES520294A priority patent/ES520294A0/es
Priority to JP58038125A priority patent/JPS58165786A/ja
Priority to IN282/CAL/83A priority patent/IN160986B/en
Priority to TR21410A priority patent/TR21410A/xx
Publication of FR2523153A1 publication Critical patent/FR2523153A1/fr
Application granted granted Critical
Publication of FR2523153B1 publication Critical patent/FR2523153B1/fr
Priority to US06/810,841 priority patent/US4757010A/en
Granted legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C12P7/28—Acetone-containing products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/145—Clostridium
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/842—Clostridium

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FR8203980A 1982-03-08 1982-03-08 Obtention de mutants de clostridium acetobutylicum a haute productivite de butanol et d'acetone, mutants obtenus et utilisation de ces mutants pour la production conjointe de butanol et d'acetone Granted FR2523153A1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR8203980A FR2523153A1 (fr) 1982-03-08 1982-03-08 Obtention de mutants de clostridium acetobutylicum a haute productivite de butanol et d'acetone, mutants obtenus et utilisation de ces mutants pour la production conjointe de butanol et d'acetone
DE8383400339T DE3361193D1 (en) 1982-03-08 1983-02-18 Production of mutants of clostridium acetobutylicum with high productivity of butanol and acetone, mutants obtained and use of these mutants in the joint production of butanol and acetone
AT83400339T ATE16509T1 (de) 1982-03-08 1983-02-18 Herstellung von clostridium acetobutylicum mutanten mit hoher butanol- und acetonausbeute, erhaltene mutanten und verwendung dieser mutanten zur gemeinsamen herstellung von butanol und aceton.
EP83400339A EP0088656B1 (fr) 1982-03-08 1983-02-18 Obtention de mutants de clostridium acétobutylicum à haute productivité de butanol et d'acétone, mutants obtenus et utilisation de ces mutants pour la production conjointe de butanol et d'acétone
ES520294A ES520294A0 (es) 1982-03-08 1983-03-04 Un procedimiento de obtencion de mutantes de clostridium acetobutylicum.
JP58038125A JPS58165786A (ja) 1982-03-08 1983-03-08 クロストリジウム・アセトブチリカムのブタノールおよびアセトン高生産性突然変異体の創製方法
IN282/CAL/83A IN160986B (enExample) 1982-03-08 1983-03-08
TR21410A TR21410A (tr) 1982-03-08 1983-03-08 Clostridium acetobutylicum'un,y*ksek b*tanol ve aseton *retkenligi olan mutantlarinin elde edilmesi,elde edilen mutantlar ve bu mutantlarin b*tanol ve asetonun birlikte *retimi icin kullanilmasi
US06/810,841 US4757010A (en) 1982-03-08 1985-12-19 Production of clostridium acetobutylicum mutants of high butanol and acetone productivity, the resultant mutants and the use of these mutants in the joint production of butanol and acetone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8203980A FR2523153A1 (fr) 1982-03-08 1982-03-08 Obtention de mutants de clostridium acetobutylicum a haute productivite de butanol et d'acetone, mutants obtenus et utilisation de ces mutants pour la production conjointe de butanol et d'acetone

Publications (2)

Publication Number Publication Date
FR2523153A1 true FR2523153A1 (fr) 1983-09-16
FR2523153B1 FR2523153B1 (enExample) 1984-08-10

Family

ID=9271812

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8203980A Granted FR2523153A1 (fr) 1982-03-08 1982-03-08 Obtention de mutants de clostridium acetobutylicum a haute productivite de butanol et d'acetone, mutants obtenus et utilisation de ces mutants pour la production conjointe de butanol et d'acetone

Country Status (9)

Country Link
US (1) US4757010A (enExample)
EP (1) EP0088656B1 (enExample)
JP (1) JPS58165786A (enExample)
AT (1) ATE16509T1 (enExample)
DE (1) DE3361193D1 (enExample)
ES (1) ES520294A0 (enExample)
FR (1) FR2523153A1 (enExample)
IN (1) IN160986B (enExample)
TR (1) TR21410A (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4737459A (en) * 1984-09-18 1988-04-12 Michigan Biotechnology Institute Regulation and enhancement of enzyme production
US5192673A (en) * 1990-04-30 1993-03-09 Michigan Biotechnology Institute Mutant strain of C. acetobutylicum and process for making butanol
JPH05244935A (ja) * 1990-10-18 1993-09-24 Intevep Sa ラクトース又は未加水分解ホエーで培養するときキサンタンガムを生産する Ｘａｎｔｈｏｍｏｎａｓ ｃａｍｐｅｓｔｒｉｓ 突然変異株
US5210032A (en) * 1992-01-21 1993-05-11 Trustees Of The Boston University Degeneration-resistant solventogenic clostridia
WO1998051813A1 (en) 1997-05-14 1998-11-19 The Board Of Trustees Of The University Of Illinois A METHOD OF PRODUCING BUTANOL USING A MUTANT STRAIN OF $i(CLOSTRIDIUM BEIJERINCKII)
US20050089979A1 (en) * 2003-09-18 2005-04-28 Ezeji Thaddeus C. Process for continuous solvent production
US7659104B2 (en) 2006-05-05 2010-02-09 E.I. Du Pont De Nemours And Company Solvent tolerant microorganisms and methods of isolation
US7541173B2 (en) * 2006-06-15 2009-06-02 E.I. Du Pont De Nemours And Company Solvent tolerant microorganisms and methods of isolation
WO2008052991A2 (en) * 2006-10-31 2008-05-08 Dsm Ip Assets B.V. Butanol production in a eukaryotic cell
US20090081715A1 (en) * 2007-09-07 2009-03-26 Cobalt Technologies, Inc., A Delaware Corporation Engineered Light-Emitting Reporter Genes
ES2643605T3 (es) * 2007-12-24 2017-11-23 Reliance Life Sciences Pvt., Ltd. Procedimiento de alto rendimiento para la producción de biobutanol
CL2009000879A1 (es) 2008-04-09 2010-05-07 Talfryn S A Metodo para fabricar un producto en un biorreactor que comprende cultivar microorganismos que son adaptados o mutagenizados para que exhiban por lo menos un 150% de tolerancia al producto; sistema para fabricar un producto; biorreactor.
WO2010046928A2 (en) * 2008-10-16 2010-04-29 Praj Industries Limited High energy biofuel composition and fermentation process for the production thereof
RU2405826C2 (ru) 2008-12-29 2010-12-10 Дэвон Инвестмент Лимитед Способ получения органических растворителей, установка для его осуществления, продукт, полученный описанным способом
US8178329B2 (en) 2009-04-01 2012-05-15 Richard Allen Kohn Process to produce organic compounds from synthesis gases
CN102482690A (zh) 2009-06-26 2012-05-30 钴技术有限公司 生物产物生产的集成系统和方法
RU2458118C1 (ru) * 2011-02-17 2012-08-10 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") Штамм бактерий clostridium acetobutylicum - продуцент н-бутанола
RU2455350C1 (ru) * 2011-03-05 2012-07-10 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") ШТАММ БАКТЕРИЙ Clostridium acetobutylicum - ПРОДУЦЕНТ н-БУТАНОЛА
NO2739722T3 (enExample) * 2011-08-01 2018-04-21

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB278307A (en) * 1926-10-01 1927-10-27 Commercial Solvents Corp Improvements in art of butyl-acetonic fermentation
GB1021721A (en) * 1962-10-05 1966-03-09 Cons Lab Inc Improvements in or relating to the production of metabolites by micro-organisms
JPS5435288A (en) * 1977-08-23 1979-03-15 Ajinomoto Co Inc Preparation of l-threonine by fermentation
US4352880A (en) * 1979-09-17 1982-10-05 Massachusetts Institute Of Technology Diffusion bioassay for the quantitative determination of mutagenicity

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EXBK/79 *
EXBK/80 *

Also Published As

Publication number Publication date
ATE16509T1 (de) 1985-11-15
EP0088656B1 (fr) 1985-11-13
JPS58165786A (ja) 1983-09-30
JPH0526460B2 (enExample) 1993-04-16
DE3361193D1 (en) 1985-12-19
ES8401130A1 (es) 1983-12-01
TR21410A (tr) 1984-05-29
IN160986B (enExample) 1987-08-29
US4757010A (en) 1988-07-12
ES520294A0 (es) 1983-12-01
FR2523153B1 (enExample) 1984-08-10
EP0088656A1 (fr) 1983-09-14

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