FR2471975B1 - Procede pour la preparation de n-mercaptoalcanoylaminoacides optiquement actifs - Google Patents
Procede pour la preparation de n-mercaptoalcanoylaminoacides optiquement actifsInfo
- Publication number
- FR2471975B1 FR2471975B1 FR8026234A FR8026234A FR2471975B1 FR 2471975 B1 FR2471975 B1 FR 2471975B1 FR 8026234 A FR8026234 A FR 8026234A FR 8026234 A FR8026234 A FR 8026234A FR 2471975 B1 FR2471975 B1 FR 2471975B1
- Authority
- FR
- France
- Prior art keywords
- formula
- bopi
- optically active
- mercaptoalcanoylaminoacids
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/58—Preparation of carboxylic acid halides
- C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Abstract
PROCEDE DE PREPARATION DE N-MERCAPTOALCANOYLAMINOACIDE OPTIQUEMENT ACTIF DE FORMULE: (CF DESSIN DANS BOPI) IL CONSISTE A FAIRE REAGIR UN COMPOSE DE FORMULE: (CF DESSIN DANS BOPI) AVEC UN REACTIF HALOGENANT; A FAIRE REAGIR LE COMPOSE OBTENU DE FORMULE:AVEC UN AMINO-ACIDE DE FORMULE: (CF DESSIN DANS BOPI) ET A FAIRE REAGIR LE COMPOSE OBTENU DE FORMULE: (CF DESSIN DANS BOPI) AVEC UN REACTIF SUSCEPTIBLE DE CONVERTIR L'HALOGENE EN GROUPE THIO. LES COMPOSES DE FORMULE (I) SONT UTILES DANS LE TRAITEMENT DE L'HYPERTENSION.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16237779A JPS5686152A (en) | 1979-12-13 | 1979-12-13 | Preparation of n-mercaptoacylamino acid |
JP16237879A JPS56108734A (en) | 1979-12-13 | 1979-12-13 | Preparation of beta-halogenoisobutyryl halide |
JP17190479A JPS5695178A (en) | 1979-12-28 | 1979-12-28 | Production of n-mercaptoalkanoylaminoacid |
JP2943080A JPS56125363A (en) | 1980-03-08 | 1980-03-08 | Preparation of thiol compound |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2471975A1 FR2471975A1 (fr) | 1981-06-26 |
FR2471975B1 true FR2471975B1 (fr) | 1985-07-05 |
Family
ID=27459067
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8026234A Expired FR2471975B1 (fr) | 1979-12-13 | 1980-12-10 | Procede pour la preparation de n-mercaptoalcanoylaminoacides optiquement actifs |
Country Status (8)
Country | Link |
---|---|
US (1) | US4371699A (fr) |
DE (1) | DE3046271A1 (fr) |
ES (1) | ES497665A0 (fr) |
FR (1) | FR2471975B1 (fr) |
GB (1) | GB2065643B (fr) |
IE (1) | IE50548B1 (fr) |
IT (1) | IT1188971B (fr) |
NL (1) | NL192264C (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4499102A (en) * | 1979-12-13 | 1985-02-12 | Santen Pharmaceutical Co., Ltd. | Thiazolidine and pyrrolidine compounds and pharmaceutical compositions containing them |
IE50839B1 (en) * | 1980-02-26 | 1986-07-23 | Wyeth John & Brother Ltd | Novel processes for preparing proline derivatives and analogous compounds |
DE3266746D1 (en) | 1981-03-12 | 1985-11-14 | Beecham Group Plc | N-carboxyalkyl dipeptide derivatives and pharmaceutical compositions thereof |
DE3143726A1 (de) * | 1981-11-04 | 1983-05-11 | Degussa Ag, 6000 Frankfurt | Optisch aktive prolin-derivate, verfahren zu ihrer herstellung und ihre verwendung |
US4634716A (en) * | 1982-09-30 | 1987-01-06 | Merck & Co., Inc. | Substituted N-carboxymethyl-aminoacylaminoalkanoic acids useful as antihypertensive agents |
US4596819A (en) * | 1984-01-23 | 1986-06-24 | Warner-Lambert Company | Modified tripeptides |
KR860001391B1 (ko) * | 1984-07-23 | 1986-09-22 | 보령제약 주식회사 | 피롤리딘 유도체의 제조방법 |
KR870001570B1 (ko) * | 1984-12-19 | 1987-09-04 | 보령제약 주식회사 | 피롤리딘 유도체의 제조방법 |
KR870001569B1 (ko) * | 1985-02-11 | 1987-09-04 | 보령제약 주식회사 | 피롤리딘 유도체의 제조방법 |
AT395012B (de) * | 1986-06-27 | 1992-08-25 | Richter Gedeon Vegyeszet | Verfahren zur herstellung von n-(1(s)|thoxycarbonyl-3-phenyl-propyl)-(s)-alanyl-(s)prolin und von dessen saeureadditionssalzen |
FI922867A (fi) * | 1991-06-21 | 1992-12-22 | Tanabe Seiyaku Co | Dikarbonsyraderivat och foerfarande foer framstaellning av dem |
JPH06199850A (ja) * | 1992-12-28 | 1994-07-19 | Tanabe Seiyaku Co Ltd | インドール含有ペプチド及びその製法 |
WO2001055074A1 (fr) * | 2000-01-25 | 2001-08-02 | Kaneka Corporation | Processus de production d'acide carboxylique optiquement actif substitue en position 2 |
US20050136666A1 (en) * | 2003-12-23 | 2005-06-23 | Tokyo Electron Limited | Method and apparatus for etching an organic layer |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4105776A (en) * | 1976-06-21 | 1978-08-08 | E. R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
AU509899B2 (en) * | 1976-02-13 | 1980-05-29 | E.R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
US4192878A (en) * | 1976-12-03 | 1980-03-11 | E. R. Squibb & Sons, Inc. | Derivatives of thiazolidinecarboxylic acids and related acids |
US4108886A (en) * | 1977-03-11 | 1978-08-22 | E. R. Squibb & Sons, Inc. | Thiopropanoylamino acid derivatives |
US4070361A (en) * | 1977-04-21 | 1978-01-24 | E. R. Squibb & Sons, Inc. | Mercaptoalkylsulfonyl proline and pipecolic acid and esters thereof |
-
1980
- 1980-12-01 GB GB8038469A patent/GB2065643B/en not_active Expired
- 1980-12-09 US US06/214,780 patent/US4371699A/en not_active Expired - Lifetime
- 1980-12-09 DE DE19803046271 patent/DE3046271A1/de active Granted
- 1980-12-10 FR FR8026234A patent/FR2471975B1/fr not_active Expired
- 1980-12-11 IT IT50342/80A patent/IT1188971B/it active
- 1980-12-12 ES ES497665A patent/ES497665A0/es active Granted
- 1980-12-12 NL NL8006768A patent/NL192264C/nl not_active IP Right Cessation
- 1980-12-12 IE IE2603/80A patent/IE50548B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FR2471975A1 (fr) | 1981-06-26 |
IT1188971B (it) | 1988-01-28 |
GB2065643A (en) | 1981-07-01 |
IT8050342A0 (it) | 1980-12-11 |
DE3046271C2 (fr) | 1988-07-28 |
IT8050342A1 (it) | 1982-06-11 |
NL192264B (nl) | 1996-12-02 |
IE802603L (en) | 1981-06-13 |
ES8200863A1 (es) | 1981-11-16 |
IE50548B1 (en) | 1986-05-14 |
US4371699A (en) | 1983-02-01 |
GB2065643B (en) | 1983-08-24 |
NL8006768A (nl) | 1981-07-16 |
ES497665A0 (es) | 1981-11-16 |
NL192264C (nl) | 1997-04-03 |
DE3046271A1 (de) | 1981-08-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |