|
DE3234203A1
(de)
*
|
1981-09-17 |
1983-07-07 |
Takeda Chemical Industries, Ltd., Osaka |
Macbecin-derivate und deren herstellung
|
|
US4578391A
(en)
*
|
1982-01-20 |
1986-03-25 |
Yamanouchi Pharmaceutical Co., Ltd. |
Oily compositions of antitumor drugs
|
|
JPS59102398A
(ja)
*
|
1982-12-03 |
1984-06-13 |
Takeda Chem Ind Ltd |
新規抗生物質およびその製造法
|
|
AU5360694A
(en)
*
|
1992-10-14 |
1994-05-09 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
Tumoricidal activity of benzoquinonoid ansamycins against prostate cancer and primitive neural malignancies
|
|
US5387584A
(en)
*
|
1993-04-07 |
1995-02-07 |
Pfizer Inc. |
Bicyclic ansamycins
|
|
WO1995001342A1
(en)
*
|
1993-06-29 |
1995-01-12 |
Pfizer Inc. |
Ansamycin derivatives as antioncogene and anticancer agents
|
|
US5932566A
(en)
*
|
1994-06-16 |
1999-08-03 |
Pfizer Inc. |
Ansamycin derivatives as antioncogene and anticancer agents
|
|
CA2218523A1
(en)
*
|
1995-05-02 |
1996-11-07 |
William J. Welch |
Inducement of thermotolerance with benzoquinonoid ansamycins
|
|
EP1023315B1
(en)
|
1997-05-14 |
2010-03-10 |
Sloan-Kettering Institute For Cancer Research |
Methods and compositions for destruction of selected proteins
|
|
US6852496B1
(en)
|
1997-08-12 |
2005-02-08 |
Oregon Health And Science University |
Methods of screening for agents that promote nerve cell growth
|
|
CA2338000C
(en)
|
1998-07-17 |
2009-12-15 |
The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Water-soluble 4-thio-maleimido derivatives and methods for their production
|
|
US6747055B1
(en)
|
1998-07-17 |
2004-06-08 |
The United States Of America As Represented By The Department Of Health And Human Services |
Water-soluble drugs and methods for their production
|
|
JP2002531512A
(ja)
*
|
1998-12-07 |
2002-09-24 |
エコスマート テクノロジーズ,インコーポレーテッド |
天然植物精油を用いた癌治療薬配合物および方法
|
|
US6174875B1
(en)
*
|
1999-04-01 |
2001-01-16 |
University Of Pittsburgh |
Benzoquinoid ansamycins for the treatment of cardiac arrest and stroke
|
|
US7238682B1
(en)
|
1999-04-09 |
2007-07-03 |
Sloan-Kettering Institute For Cancer Research |
Methods and compositions for degradation and/or inhibition of HER-family tyrosine kinases
|
|
AU769235B2
(en)
|
1999-04-09 |
2004-01-22 |
Sloan-Kettering Institute For Cancer Research |
Methods and compositions for degradation and/or inhibition of her-family tyrosine kinases
|
|
US6979574B1
(en)
*
|
1999-08-06 |
2005-12-27 |
Institut Fuer Diagnostik Forshung Gmbh |
Process for detecting binding reactions with use of the measurement of the relaxation of the double refraction of magnetic particles
|
|
AU2001271567A1
(en)
*
|
2000-06-29 |
2002-01-14 |
Trustees Of Boston University |
Use of geldanamycin and related compounds for prophylaxis or treatment of fibrogenic disorders
|
|
JP2004505044A
(ja)
|
2000-07-28 |
2004-02-19 |
スローン−ケッタリング・インスティテュート・フォー・キャンサー・リサーチ |
細胞増殖性障害およびウイルス感染の治療方法
|
|
EP1337275A4
(en)
|
2000-11-02 |
2007-05-09 |
Sloan Kettering Inst Cancer |
METHOD FOR ENHANCING THE EFFICACY OF CYTOTOXIC AGENTS USING HSP 90 INHIBITORS
|
|
AU2002252179A1
(en)
*
|
2001-03-01 |
2002-09-19 |
Conforma Therapeutics Corp. |
Methods for treating genetically-defined proliferative disorders with hsp90 inhibitors
|
|
WO2002079167A1
(en)
*
|
2001-03-30 |
2002-10-10 |
The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Geldanamycin derivative and method of treating cancer using same
|
|
EP1404871A4
(en)
*
|
2001-05-23 |
2006-10-04 |
Sloan Kettering Inst Cancer |
METHOD OF TREATING CANCERS ASSOCIATED WITH LEVELS OF HER-2 STUDENTS
|
|
US6872715B2
(en)
|
2001-08-06 |
2005-03-29 |
Kosan Biosciences, Inc. |
Benzoquinone ansamycins
|
|
US20090197852A9
(en)
*
|
2001-08-06 |
2009-08-06 |
Johnson Robert G Jr |
Method of treating breast cancer using 17-AAG or 17-AG or a prodrug of either in combination with a HER2 inhibitor
|
|
AU2002330998A1
(en)
*
|
2001-08-06 |
2003-02-24 |
Kosan Biosciences, Inc. |
Benzoquinone ansamycins
|
|
EP1923061A1
(en)
|
2001-09-24 |
2008-05-21 |
Conforma Therapeutic Corporation |
Process for preparing 17-Allyl amino geldanamycin (17-AAG) and other ansamycins
|
|
CN100378079C
(zh)
*
|
2001-09-24 |
2008-04-02 |
康福玛医药公司 |
用于制备17-烯丙基氨基格尔德霉素(17-aag)以及其它袢霉素的方法
|
|
US7465718B2
(en)
*
|
2002-02-08 |
2008-12-16 |
Conforma Therapeutics Corporation |
Ansamycins having improved pharmacological and biological properties
|
|
EP1492522A4
(en)
*
|
2002-04-10 |
2009-01-14 |
Conforma Therapeutics Corp |
ANSAMYCIN FORMULATIONS AND METHODS OF MAKING AND USING THE SAME
|
|
US20060148776A1
(en)
*
|
2003-03-13 |
2006-07-06 |
Conforma Therapeutics Corporation |
Drug formulations having long and medium chain triglycerides
|
|
US20050054625A1
(en)
*
|
2003-05-30 |
2005-03-10 |
Kosan Biosciences, Inc. |
Method for treating diseases using HSP90-inhibiting agents in combination with nuclear export inhibitors
|
|
US7691838B2
(en)
*
|
2003-05-30 |
2010-04-06 |
Kosan Biosciences Incorporated |
Method for treating diseases using HSP90-inhibiting agents in combination with antimitotics
|
|
US20050020534A1
(en)
*
|
2003-05-30 |
2005-01-27 |
Kosan Biosciences, Inc. |
Method for treating diseases using HSP90-inhibiting agents in combination with antimetabolites
|
|
US20050020556A1
(en)
*
|
2003-05-30 |
2005-01-27 |
Kosan Biosciences, Inc. |
Method for treating diseases using HSP90-inhibiting agents in combination with platinum coordination complexes
|
|
US20050026893A1
(en)
*
|
2003-05-30 |
2005-02-03 |
Kosan Biosciences, Inc. |
Method for treating diseases using HSP90-inhibiting agents in combination with immunosuppressants
|
|
US20050020557A1
(en)
*
|
2003-05-30 |
2005-01-27 |
Kosan Biosciences, Inc. |
Method for treating diseases using HSP90-inhibiting agents in combination with enzyme inhibitors
|
|
US20050054589A1
(en)
*
|
2003-05-30 |
2005-03-10 |
Kosan Biosciences, Inc. |
Method for treating diseases using HSP90-inhibiting agents in combination with antibiotics
|
|
US7241754B2
(en)
*
|
2003-06-13 |
2007-07-10 |
Kosan Biosciences, Inc. |
2-Desmethyl ansamycin compounds
|
|
US6855705B1
(en)
|
2003-11-12 |
2005-02-15 |
Kosan Biosciences, Inc. |
11-O-methylgeldanamycin compounds
|
|
WO2005056531A1
(en)
|
2003-11-12 |
2005-06-23 |
Kosan Biosciences, Inc. |
11-o-methylgeldanamycin compounds
|
|
US6887993B1
(en)
|
2003-11-12 |
2005-05-03 |
Kosan Biosciences, Inc. |
11-O-methylgeldanamycin compounds
|
|
US6875863B1
(en)
|
2003-11-12 |
2005-04-05 |
Kosan Biosciences, Inc. |
11-O-methylgeldanamycin compounds
|
|
WO2005063714A1
(en)
|
2003-12-23 |
2005-07-14 |
Infinity Pharmaceuticals, Inc |
Analogs of benzoquinone-containing ansamycins for the treatment of cancer
|
|
US20060019941A1
(en)
*
|
2003-12-23 |
2006-01-26 |
Infinity Pharmaceuticals, Inc. |
Analogs of benzoquinone-containing ansamycins and methods of use thereof
|
|
WO2005072766A2
(en)
*
|
2004-01-27 |
2005-08-11 |
Boys Town National Research Hospital |
Peptides that bind to hsp90 proteins
|
|
ES2566973T3
(es)
|
2004-03-15 |
2016-04-18 |
Sunesis Pharmaceuticals, Inc. |
Uso de SNS-595 para tratar leucemia
|
|
WO2005105077A1
(en)
*
|
2004-04-28 |
2005-11-10 |
Massachusetts Eye & Ear Infirmary |
Inflammatory eye disease
|
|
US20050256097A1
(en)
*
|
2004-05-11 |
2005-11-17 |
Kosan Biosciences, Inc. |
Pharmaceutical solution formulations containing 17-AAG
|
|
US7259156B2
(en)
|
2004-05-20 |
2007-08-21 |
Kosan Biosciences Incorporated |
Geldanamycin compounds and method of use
|
|
WO2006034147A2
(en)
*
|
2004-09-16 |
2006-03-30 |
Abraxis Bioscience, Inc. |
Compositions and methods for the preparation and administration of poorly water soluble drugs
|
|
US20060067953A1
(en)
*
|
2004-09-29 |
2006-03-30 |
Conforma Therapeutics Corporation |
Oral pharmaceutical formulations and methods for producing and using same
|
|
EP3345631A1
(en)
*
|
2005-02-18 |
2018-07-11 |
Abraxis BioScience, LLC |
Drugs with improved hydrophobicity for incorporation in medical devices
|
|
AU2006230447A1
(en)
|
2005-03-30 |
2006-10-05 |
Conforma Therapeutics Corporation |
Alkynyl pyrrolopyrimidines and related analogs as HSP90-inhibitors
|
|
CN101189006A
(zh)
*
|
2005-04-07 |
2008-05-28 |
康福玛医药公司 |
基于磷脂的药物制剂及其生产和使用方法
|
|
US8173167B2
(en)
|
2005-04-12 |
2012-05-08 |
Wisconsin Alumni Research Foundation |
Micelle composition of polymer and passenger drug
|
|
KR20080000682A
(ko)
*
|
2005-04-29 |
2008-01-02 |
코산 바이오사이언시즈, 인코포레이티드 |
17-aag 또는 17-ag, 또는 이들의 프로드럭을 사용한다발성 골수종의 치료 방법
|
|
EP1874297A4
(en)
*
|
2005-04-29 |
2009-04-22 |
Kosan Biosciences Inc |
METHOD OF TREATING MULTIPLE MYELOMES USING 17AGENE OR 17-AG OR A PRODRUG OR ALL IN COMBINATION WITH A PROTEASOMIC INHIBITOR
|
|
US20080032719A1
(en)
*
|
2005-10-01 |
2008-02-07 |
Outland Research, Llc |
Centralized establishment-based tracking and messaging service
|
|
EP1906950A4
(en)
*
|
2005-06-21 |
2008-09-24 |
Infinity Discovery Inc |
ANSAMYCIN FORMULATIONS AND METHODS OF USE
|
|
US8580814B2
(en)
*
|
2006-04-03 |
2013-11-12 |
Sunesis Pharmaceuticals, Inc. |
Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
|
|
EP1937258A2
(en)
*
|
2005-09-23 |
2008-07-02 |
Conforma Therapeutics Corporation |
Anti-tumor methods using multi drug resistance independent synthetic hsp90 inhibitors
|
|
US20090042847A1
(en)
*
|
2005-11-23 |
2009-02-12 |
Kosan Biosciences Incorporated |
17-allylamino-17-demethoxygeldanamycin polymorphs and formulations
|
|
US7648976B2
(en)
*
|
2005-11-23 |
2010-01-19 |
Bristol-Myers Squibb Company |
17-allylamino-17-demethoxygeldanamycin polymorphs and formulations
|
|
EP1954265A2
(en)
*
|
2005-12-01 |
2008-08-13 |
Conforma Therapeutics Corporation |
Compositions containing ansamycin
|
|
US20070167422A1
(en)
*
|
2006-01-18 |
2007-07-19 |
Yu Kwok S |
Pharmaceutical compositions comprising 17-allylamino-17-demethoxygeldanamycin
|
|
WO2007097839A2
(en)
*
|
2006-02-16 |
2007-08-30 |
Massachusetts Eye And Ear Infirmary |
Ansamycin analogs or heat shock 90 inhibitors in combination with pdt treatin conditions of the eye
|
|
EP2043645A2
(en)
|
2006-06-12 |
2009-04-08 |
Sunesis Pharmaceuticals, Inc. |
Compounds and compositions for treatment of cancer
|
|
EP2049109B1
(en)
*
|
2006-08-02 |
2015-11-18 |
Sunesis Pharmaceuticals, Inc. |
Combined use of (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid and cytarabine (ara-c) for the treatment of leukemia
|
|
PE20081506A1
(es)
*
|
2006-12-12 |
2008-12-09 |
Infinity Discovery Inc |
Formulaciones de ansamicina
|
|
EP2121957A4
(en)
|
2007-01-26 |
2010-11-10 |
Kosan Biosciences Inc |
MACROLACTAMES OBTAINED BY MODIFIED BIOSYNTHESIS
|
|
WO2008118601A2
(en)
*
|
2007-02-27 |
2008-10-02 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Radiolabeled affibody molecules
|
|
MX2009010667A
(es)
*
|
2007-04-12 |
2010-02-24 |
Joyant Pharmaceuticals Inc |
Dimeros y trimeros mimeticos de smac utiles como agentes anti-cancer.
|
|
JP2010523710A
(ja)
*
|
2007-04-12 |
2010-07-15 |
インフィニティ・ディスカバリー・インコーポレイテッド |
ヒドロキノンアンサマイシン製剤
|
|
JP2010533180A
(ja)
*
|
2007-07-09 |
2010-10-21 |
グレン エス. クウォン, |
治療剤
|
|
US8551964B2
(en)
|
2007-08-23 |
2013-10-08 |
The Regents Of The University Of Colorado |
Hsp90 inhibitors with modified toxicity
|
|
WO2009036092A2
(en)
*
|
2007-09-10 |
2009-03-19 |
University Of Massachusetts |
Mitochondria-targeted anti-tumor agents
|
|
EP3141250A1
(en)
*
|
2007-10-22 |
2017-03-15 |
Sunesis Pharmaceuticals, Inc. |
Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid in combination therapy
|
|
WO2009086170A1
(en)
*
|
2007-12-21 |
2009-07-09 |
Joyant Pharmaceuticals, Inc. |
Diazonamide analogs with improved solubility
|
|
CN101220068B
(zh)
*
|
2008-01-18 |
2012-06-13 |
中国医学科学院医药生物技术研究所 |
一组格尔德霉素衍生物及其制备方法
|
|
US20090258869A1
(en)
*
|
2008-02-08 |
2009-10-15 |
The Regents Of The University Of California |
Methods and compounds for treatment or prevention of substance-related disorders
|
|
WO2009134938A1
(en)
*
|
2008-04-29 |
2009-11-05 |
Joyant Pharmaceuticals, Inc. |
Indoline anti-cancer agents
|
|
US8153619B2
(en)
*
|
2008-05-22 |
2012-04-10 |
Joyant Pharmaceuticals, Inc. |
Diazonamide analogs
|
|
CA2739928A1
(en)
*
|
2008-10-15 |
2010-04-22 |
Infinity Pharmaceuticals, Inc. |
Ansamycin hydroquinone compositions
|
|
DE102008060549A1
(de)
|
2008-12-04 |
2010-06-10 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung
|
|
KR101721281B1
(ko)
|
2009-09-25 |
2017-04-10 |
위스콘신 얼럼나이 리서어치 화운데이션 |
치료제의 미셀 캡슐화
|
|
EP2471918A4
(en)
|
2009-09-29 |
2013-06-05 |
Takeda Pharmaceutical |
SCREENING METHOD
|
|
WO2011059763A2
(en)
|
2009-10-28 |
2011-05-19 |
Joyant Pharmaceuticals, Inc. |
Dimeric smac mimetics
|
|
CN102603635B
(zh)
*
|
2011-01-21 |
2016-08-03 |
杭州华东医药集团生物工程研究所有限公司 |
格尔德霉素衍生物及其制备方法和用途
|
|
RU2608308C2
(ru)
|
2011-04-22 |
2017-01-17 |
Джоянт Фармасьютикалс, Инк. |
Аналоги диазонамида
|
|
US8945627B2
(en)
|
2011-05-05 |
2015-02-03 |
Wisconsin Alumni Research Foundation |
Micelles for the solubilization of gossypol
|
|
MX2014004559A
(es)
|
2011-10-14 |
2014-08-01 |
Novartis Ag |
Derivados de 2-carboxamida cicloamino urea en combinacion con inhibidores de hsp90 para el tratamiento de enfermedades proliferativas.
|
|
WO2013074695A1
(en)
|
2011-11-14 |
2013-05-23 |
The Regents Of The University Of Colorado, A Body Corporate |
Hsp90 inhibitors with modified toxicity
|
|
JP6158833B2
(ja)
|
2012-01-09 |
2017-07-05 |
アローヘッド ファーマシューティカルズ インコーポレイテッド |
ベータ−カテニン関連疾患を処置するための有機組成物
|
|
UY34632A
(es)
|
2012-02-24 |
2013-05-31 |
Novartis Ag |
Compuestos de oxazolidin- 2- ona y usos de los mismos
|
|
EP3795694A3
(en)
|
2012-10-02 |
2021-06-23 |
The General Hospital Corporation d/b/a Massachusetts General Hospital |
Methods relating to dna-sensing pathway related conditions
|
|
AU2013341271A1
(en)
|
2012-11-07 |
2015-05-14 |
Novartis Ag |
Combination therapy
|
|
RS57106B1
(sr)
|
2013-02-19 |
2018-06-29 |
Novartis Ag |
Derivati benzotiofena i njihove kompozicije kao selektivni degraderi estrogenskog receptora
|
|
CN103360312B
(zh)
*
|
2013-07-22 |
2015-06-03 |
山东大学 |
一组格尔德霉素衍生物及其应用
|
|
CN105764501A
(zh)
|
2013-07-26 |
2016-07-13 |
现代化制药公司 |
改善比生群治疗效益的组合物
|
|
WO2015092634A1
(en)
|
2013-12-16 |
2015-06-25 |
Novartis Ag |
1,2,3,4-tetrahydroisoquinoline compounds and compositions as selective estrogen receptor antagonists and degraders
|
|
CN105899491B
(zh)
|
2014-01-17 |
2019-04-02 |
诺华股份有限公司 |
用于抑制shp2活性的1-哒嗪-/三嗪-3-基-哌(-嗪)/啶/吡咯烷衍生物及其组合物
|
|
JO3517B1
(ar)
|
2014-01-17 |
2020-07-05 |
Novartis Ag |
ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2
|
|
WO2015107494A1
(en)
|
2014-01-17 |
2015-07-23 |
Novartis Ag |
1 -(triazin-3-yi_/pyridazin-3-yl)-piper(-azine)idine derivatives and compositions thereof for inhibiting the activity of shp2
|
|
BR112017016817A2
(pt)
|
2015-03-25 |
2018-04-03 |
Novartis Ag |
derivados heterocíclicos formilados como inibidores de fgfr4
|
|
EP3307264A1
(en)
|
2015-06-12 |
2018-04-18 |
Wisconsin Alumni Research Foundation |
Multi-drug combinations that act as potent radiosensitizers
|
|
EP3310779B1
(en)
|
2015-06-19 |
2019-05-08 |
Novartis AG |
Compounds and compositions for inhibiting the activity of shp2
|
|
WO2016203406A1
(en)
|
2015-06-19 |
2016-12-22 |
Novartis Ag |
Compounds and compositions for inhibiting the activity of shp2
|
|
EP3310771B1
(en)
|
2015-06-19 |
2020-07-22 |
Novartis AG |
Compounds and compositions for inhibiting the activity of shp2
|
|
MA44334A
(fr)
|
2015-10-29 |
2018-09-05 |
Novartis Ag |
Conjugués d'anticorps comprenant un agoniste du récepteur de type toll
|
|
CA3023032A1
(en)
|
2016-05-04 |
2017-11-09 |
Genoscience Pharma |
Substituted 2,4-diamino-quinoline derivatives for use in the treatment of proliferative diseases
|
|
KR102457146B1
(ko)
|
2016-06-14 |
2022-10-19 |
노파르티스 아게 |
Shp2의 활성을 억제하기 위한 화합물 및 조성물
|
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
|
TW202517628A
(zh)
|
2017-09-11 |
2025-05-01 |
美商克魯松藥物公司 |
Shp2之八氫環戊烷并[c]吡咯別構抑制劑
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
CN112584875A
(zh)
|
2018-07-25 |
2021-03-30 |
先进加速器应用公司 |
稳定的、浓缩的放射性核素络合物溶液
|
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
|
BR112021005082A2
(pt)
|
2018-09-18 |
2021-06-08 |
Nikang Therapeutics, Inc. |
derivados de anel tricíclico fundido como inibidores de src homologia-2 fosfatase
|
|
WO2020064693A1
(en)
|
2018-09-25 |
2020-04-02 |
Advanced Accelerator Applications (Italy) Srl |
Combination therapy
|
|
CN113164776A
(zh)
|
2018-09-25 |
2021-07-23 |
黑钻治疗公司 |
酪氨酸激酶抑制剂组合物、其制备方法和使用方法
|
|
KR20210137422A
(ko)
|
2018-09-25 |
2021-11-17 |
블랙 다이아몬드 테라퓨틱스, 인코포레이티드 |
티로신 키나아제 억제제로서의 퀴나졸린 유도체, 조성물, 이들의 제조 방법 및 이들의 용도
|
|
EP3856345A1
(en)
|
2018-09-29 |
2021-08-04 |
Novartis AG |
Process of manufacture of a compound for inhibiting the activity of shp2
|
|
CA3123511A1
(en)
|
2018-12-20 |
2020-06-25 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
EP3924054B1
(en)
|
2019-02-15 |
2025-04-02 |
Novartis AG |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
MX2021009764A
(es)
|
2019-02-15 |
2021-09-08 |
Novartis Ag |
Derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona sustituidos y usos de los mismos.
|
|
US12435046B2
(en)
|
2019-08-15 |
2025-10-07 |
Black Diamond Therapeutics, Inc. |
Alkynyl quinazoline compounds
|
|
CN115175937A
(zh)
|
2019-12-20 |
2022-10-11 |
诺华股份有限公司 |
用于治疗骨髓纤维化和骨髓增生异常综合征的抗TIM-3抗体MBG453和抗TGF-β抗体NIS793与或不与地西他滨或抗PD-1抗体斯巴达珠单抗的组合
|
|
WO2021195206A1
(en)
|
2020-03-24 |
2021-09-30 |
Black Diamond Therapeutics, Inc. |
Polymorphic forms and related uses
|
|
CA3182346A1
(en)
|
2020-06-23 |
2021-12-30 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
US20230271940A1
(en)
|
2020-08-03 |
2023-08-31 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
WO2022043556A1
(en)
|
2020-08-31 |
2022-03-03 |
Novartis Ag |
Stable radiopharmaceutical composition
|
|
EP4204020A1
(en)
|
2020-08-31 |
2023-07-05 |
Advanced Accelerator Applications International S.A. |
Method of treating psma-expressing cancers
|
|
WO2022043557A1
(en)
|
2020-08-31 |
2022-03-03 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
EP4267575A1
(en)
|
2020-12-22 |
2023-11-01 |
Nikang Therapeutics, Inc. |
Compounds for degrading cyclin-dependent kinase 2 via ubiquitin proteosome pathway
|
|
AU2022207648A1
(en)
|
2021-01-13 |
2023-07-27 |
Monte Rosa Therapeutics Ag |
Isoindolinone compounds
|
|
WO2022170052A1
(en)
|
2021-02-05 |
2022-08-11 |
Black Diamond Therapeutics, Inc. |
Quinazoline derivatives, pyridopyrimidine derivatives, pyrimidopyrimidine derivatives, and uses thereof
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
EP4323349A1
(en)
|
2021-04-14 |
2024-02-21 |
Monte Rosa Therapeutics AG |
Isoindolinone amide compounds useful to treat diseases associated with gspt1
|
|
WO2022219407A1
(en)
|
2021-04-14 |
2022-10-20 |
Monte Rosa Therapeutics Ag |
Isoindolinone compounds
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
EP4370522A1
(en)
|
2021-07-14 |
2024-05-22 |
Nikang Therapeutics, Inc. |
Alkylidene derivatives as kras inhibitors
|
|
WO2023192801A1
(en)
|
2022-03-28 |
2023-10-05 |
Nikang Therapeutics, Inc. |
Sulfonamido derivatives as cyclin-dependent kinase 2 inhibitors
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
WO2023240024A1
(en)
|
2022-06-08 |
2023-12-14 |
Nikang Therapeutics, Inc. |
Sulfamide derivatives as cyclin-dependent kinase 2 inhibitors
|
|
TW202434563A
(zh)
|
2022-11-11 |
2024-09-01 |
美商尼坎醫療公司 |
用於經由泛素蛋白酶體途徑降解週期蛋白依賴性激酶2的含有2,5-取代的嘧啶衍生物之雙功能化合物
|
|
WO2025072462A1
(en)
|
2023-09-27 |
2025-04-03 |
Nikang Therapeutics, Inc. |
Sulfonamide derivatives as cyclin-dependent kinase 2 inhibitors
|
|
TW202527955A
(zh)
|
2023-11-27 |
2025-07-16 |
美商尼坎醫療公司 |
用於經由泛素蛋白酶體途徑降解週期蛋白依賴性激酶2和週期蛋白依賴性激酶4的含有2,5-取代的嘧啶衍生物的雙功能化合物
|
|
WO2025117981A1
(en)
|
2023-12-02 |
2025-06-05 |
Nikang Therapeutics, Inc. |
Bifunctional compounds containing 2,5-substituted pyrimidine derivatives for degrading cyclin-dependent kinase 2 via ubiquitin proteasome pathway
|
|
WO2025212828A1
(en)
|
2024-04-03 |
2025-10-09 |
Nikang Therapeutics, Inc. |
Bifunctional compounds containing 2,5-substituted pyrimidine derivatives for degrading cyclin-dependent kinase 2 and cyclin-dependent kinase 4 via ubiquitin proteasome pathway
|
|
WO2025240536A1
(en)
|
2024-05-15 |
2025-11-20 |
Nikang Therapeutics, Inc. |
Bifunctional compounds containing 2,5-substituted pyrimidine derivatives for degrading cyclin-dependent kinase 2 and/or cyclin-dependent kinase 4 via ubiquitin proteasome pathway
|