FR2447191A1 - Preparation medicale contenant de la prostaglandine et son utilisation pour application intravaginale et intracervicale - Google Patents

Preparation medicale contenant de la prostaglandine et son utilisation pour application intravaginale et intracervicale

Info

Publication number
FR2447191A1
FR2447191A1 FR8001797A FR8001797A FR2447191A1 FR 2447191 A1 FR2447191 A1 FR 2447191A1 FR 8001797 A FR8001797 A FR 8001797A FR 8001797 A FR8001797 A FR 8001797A FR 2447191 A1 FR2447191 A1 FR 2447191A1
Authority
FR
France
Prior art keywords
intravaginal
medical preparation
preparation containing
intracervical
containing prostaglandin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8001797A
Other languages
English (en)
Other versions
FR2447191B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Perstorp AB
Original Assignee
Perstorp AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Perstorp AB filed Critical Perstorp AB
Publication of FR2447191A1 publication Critical patent/FR2447191A1/fr
Application granted granted Critical
Publication of FR2447191B1 publication Critical patent/FR2447191B1/fr
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

LA PRESENTE INVENTION DECRIT UNE PREPARATION MEDICALE STABLE SOUS LA FORME DE PARTICULES ESSENTIELLEMENT SECHES, CONTENANT DE LA PROSTAGLANDINE ABSORBEE ETOU ADSORBEE DANS UN POLYMERE RETICULE RENFERMANT DES GROUPES HYDROXYLE, QUI EST INSOLUBLE DANS L'EAU, MAIS POSSEDE UNE APTITUDE AU GONFLEMENT DANS LES LIQUIDES CONTENANT DE L'EAU POUR FORMER UN GEL. UTILISATION DE CETTE PREPARATION POUR DES APPLICATIONS INTRAVAGINALES ETOU INTRACERVICALES.
FR8001797A 1979-01-29 1980-01-28 Preparation medicale contenant de la prostaglandine et son utilisation pour application intravaginale et intracervicale Granted FR2447191A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7900737A SE431821B (sv) 1979-01-29 1979-01-29 Lagringsstabilt, prostaglandininnehallande medicinskt preparat

Publications (2)

Publication Number Publication Date
FR2447191A1 true FR2447191A1 (fr) 1980-08-22
FR2447191B1 FR2447191B1 (fr) 1983-07-22

Family

ID=20337129

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8001797A Granted FR2447191A1 (fr) 1979-01-29 1980-01-28 Preparation medicale contenant de la prostaglandine et son utilisation pour application intravaginale et intracervicale

Country Status (10)

Country Link
US (1) US4352790A (fr)
JP (1) JPS55102512A (fr)
BE (1) BE881351A (fr)
DE (1) DE3001454A1 (fr)
DK (2) DK160739C (fr)
FR (1) FR2447191A1 (fr)
GB (1) GB2041220B (fr)
NL (1) NL190693C (fr)
NO (1) NO153520C (fr)
SE (2) SE431821B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0116358A1 (fr) * 1983-02-12 1984-08-22 Bayer Ag Complexes de prostaglandines

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079009A (en) * 1979-03-21 1992-01-07 National Research Development Corporation Controlled release compositions including polyethylene oxide with urethane cross-linking
AU537741B2 (en) * 1979-03-21 1984-07-12 British Technology Group Limited Controlled release compositions
IT1131833B (it) * 1980-06-20 1986-06-25 Crinos Industria Farmaco Eccipienti per sostanze spermicide
ZA831186B (en) * 1982-03-22 1983-11-30 Upjohn Ltd Gelled pge2/triacetin solutions
AU546872B2 (en) * 1982-06-16 1985-09-26 Unilever Plc Skin treatment compositions containing a fatty acid or ester
DE3307816A1 (de) * 1983-03-02 1984-09-06 Schering AG, 1000 Berlin und 4709 Bergkamen Prostaglandin-haltiges pharmazeutisches praeparat und seine herstellung
GB8403360D0 (en) * 1984-02-08 1984-03-14 Erba Farmitalia Pharmaceutical compositions
DE3428264A1 (de) * 1984-07-27 1986-03-06 Schering Ag Gelhaltige pharmazeutische zubereitungen
IE59361B1 (en) 1986-01-24 1994-02-09 Akzo Nv Pharmaceutical preparation for obtaining a highly viscous hydrogel or suspension
JP2590358B2 (ja) * 1988-03-01 1997-03-12 正雄 五十嵐 子宮内膜症治療用の子宮内又は膣内投与製剤
JPH03220201A (ja) * 1988-11-18 1991-09-27 Eisai Co Ltd プロスタグランジン類と多糖類の結合体
CH678697A5 (fr) * 1989-04-03 1991-10-31 Warner Lambert Co
US5491171A (en) * 1991-11-08 1996-02-13 Kyoto Pharmaceutical Industries, Ltd. Pharmaceutical preparation containing prostaglandin compound for rectal or vaginal administration
US6946442B2 (en) * 1994-11-30 2005-09-20 Asif Syed Ahmed Method of hastening cervical ripening
JPH11506100A (ja) * 1995-06-01 1999-06-02 ジー.ディー.サール アンド カンパニー ミソプロストールの安定化された分散系
KR20010021625A (ko) 1997-07-09 2001-03-15 추후보정 개선된 남성발기 기능장애 치료방법 및 그 조성물
US6103765A (en) 1997-07-09 2000-08-15 Androsolutions, Inc. Methods for treating male erectile dysfunction
FR2766709B1 (fr) 1997-07-31 2000-04-07 Dominique Cingotti Procede pour la preparation d'un extrait de principes actifs sous forme de microgranules a base de fibres alimentaires entierement solubles destines a differentes formes galeniques
US6031002A (en) * 1998-05-01 2000-02-29 Michael Ebert Method for enhancing female sexual response and a composition therefor
US5891915A (en) * 1998-05-01 1999-04-06 Wysor; Michael S. Method for enhancing female sexual response and an ointment therefor
US6825234B2 (en) 1998-12-10 2004-11-30 Nexmed (Holdings) , Inc. Compositions and methods for amelioration of human female sexual dysfunction
US6486207B2 (en) 1998-12-10 2002-11-26 Nexmed (Holdings), Inc. Compositions and methods for amelioration of human female sexual dysfunction
US20070191320A1 (en) * 1998-12-10 2007-08-16 Nexmed Holdings, Inc. Methods of treatment for female sexual arousal disorder
GR1004266B (el) * 2001-04-30 2003-06-18 Ηλιας Κ. Παπαδοπουλος Φαρμακευτικο παρασκευασμα για την διαγνωση και θεραπεια της στυτικης δυσλειτουργιας
US20050181030A1 (en) * 2003-01-03 2005-08-18 Mo Y. J. Topical stabilized prostaglandin E compound dosage forms

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2210415A1 (fr) * 1972-12-18 1974-07-12 Ortho Pharma Corp
US3888975A (en) * 1972-12-27 1975-06-10 Alza Corp Erodible intrauterine device
US3948254A (en) * 1971-11-08 1976-04-06 Alza Corporation Novel drug delivery device
GB1516348A (en) * 1974-09-18 1978-07-05 Pharma Soc Of Victoria Injectable compositions
FR2373279A1 (fr) * 1976-12-13 1978-07-07 Ici Ltd Composition a base d'un copolymere sequence pour la liberation prolongee d'un agent doue d'activite biologique

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4036954A (en) * 1973-11-02 1977-07-19 Yamanouchi Pharmaceutical Co., Ltd. Stable prostaglandin E group-containing formulation
AR205997A1 (es) 1973-11-21 1976-06-23 American Cyanamid Co Resina de poliester normalmente solida biodegradable e hidrolizable
CH616694A5 (en) * 1974-06-27 1980-04-15 Ciba Geigy Ag Process for the preparation of crosslinked, water-insoluble, hydrophilic copolymers
JPS5256148A (en) * 1975-10-16 1977-05-09 Agency Of Ind Science & Technol Process for preparing active substances having improved
GB1554783A (en) 1976-01-05 1979-10-31 Population Res Inc Pharmaceutical compositions for use in the permanent sterilization of female animals
DE2709804C2 (de) * 1976-03-12 1986-03-13 Ono Pharmaceutical Co. Ltd., Osaka Prostaglandin-analoga, Verfahren zu ihrer Herstellung, sowie diese enthaltende pharmazeutische Zusammensetzungen

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3948254A (en) * 1971-11-08 1976-04-06 Alza Corporation Novel drug delivery device
FR2210415A1 (fr) * 1972-12-18 1974-07-12 Ortho Pharma Corp
GB1446626A (en) * 1972-12-18 1976-08-18 Ortho Pharma Corp Composition for sustained release of a medicament and method of using same
US3888975A (en) * 1972-12-27 1975-06-10 Alza Corp Erodible intrauterine device
GB1516348A (en) * 1974-09-18 1978-07-05 Pharma Soc Of Victoria Injectable compositions
FR2373279A1 (fr) * 1976-12-13 1978-07-07 Ici Ltd Composition a base d'un copolymere sequence pour la liberation prolongee d'un agent doue d'activite biologique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1980 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0116358A1 (fr) * 1983-02-12 1984-08-22 Bayer Ag Complexes de prostaglandines

Also Published As

Publication number Publication date
JPS55102512A (en) 1980-08-05
DK160740C (da) 1991-09-30
NO153520B (no) 1985-12-30
DE3001454C2 (fr) 1990-05-10
US4352790A (en) 1982-10-05
DE3001454A1 (de) 1980-08-07
DK316186A (da) 1986-07-03
GB2041220A (en) 1980-09-10
GB2041220B (en) 1983-07-27
NL190693C (nl) 1994-07-01
DK33580A (da) 1980-07-30
BE881351A (fr) 1980-05-16
NL8000426A (nl) 1980-07-31
NL190693B (nl) 1994-02-01
SE7910354L (sv) 1980-07-30
SE431821B (sv) 1984-03-05
DK316186D0 (da) 1986-07-03
NO800186L (no) 1980-07-30
SE7900737L (sv) 1980-07-30
DK160739C (da) 1991-09-30
FR2447191B1 (fr) 1983-07-22
SE442167B (sv) 1985-12-09
DK160740B (da) 1991-04-15
JPH0140013B2 (fr) 1989-08-24
NO153520C (no) 1986-04-09
DK160739B (da) 1991-04-15

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Legal Events

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ST Notification of lapse
RC Opposition against decision of lapse
DA Annulment of decision of lapse