FR2446843A1 - Procede de preparation de derives immunoregulateurs de copolymeres de monomeres olefiniques et d'anhydrides polycarboxyliques et nouvelles compositions ainsi obtenues - Google Patents

Procede de preparation de derives immunoregulateurs de copolymeres de monomeres olefiniques et d'anhydrides polycarboxyliques et nouvelles compositions ainsi obtenues

Info

Publication number
FR2446843A1
FR2446843A1 FR8001201A FR8001201A FR2446843A1 FR 2446843 A1 FR2446843 A1 FR 2446843A1 FR 8001201 A FR8001201 A FR 8001201A FR 8001201 A FR8001201 A FR 8001201A FR 2446843 A1 FR2446843 A1 FR 2446843A1
Authority
FR
France
Prior art keywords
copolymers
derivatives
immunoregulatory
polycarboxyl
anhydrides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8001201A
Other languages
English (en)
Other versions
FR2446843B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of FR2446843A1 publication Critical patent/FR2446843A1/fr
Application granted granted Critical
Publication of FR2446843B1 publication Critical patent/FR2446843B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/44Preparation of metal salts or ammonium salts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

On décrit des copolymères de monomères oléfiniques ayant 2 à environ 4 atomes de carbone et d'anhydrides polycarboxyliques à insaturation en alpha , beta ayant 4 à environ 6 atomes de carbone, à poids moléculaire moyen d'environ 300 à environ 1 500, et dont on a constitué des dérivés pour qu'ils contiennent une fonction semi-amide, semi-sel formé de carboxylate et une fonction imide, cette fonction imide formant environ 5 % à environ 40 % de cette fonction dérivée; ces copolymères sont utiles pour la conduite de la thérapie des tumeurs, afin d'empêcher la récurrence de tumeurs ou le développement de metastases par un mécanisme immunorégulateur.
FR8001201A 1979-01-22 1980-01-21 Procede de preparation de derives immunoregulateurs de copolymeres de monomeres olefiniques et d'anhydrides polycarboxyliques et nouvelles compositions ainsi obtenues Granted FR2446843A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/005,638 US4255537A (en) 1979-01-22 1979-01-22 Polymeric immunoregulatory agents containing half-amide/half carboxy/imide groups

Publications (2)

Publication Number Publication Date
FR2446843A1 true FR2446843A1 (fr) 1980-08-14
FR2446843B1 FR2446843B1 (fr) 1984-03-16

Family

ID=21716914

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8001201A Granted FR2446843A1 (fr) 1979-01-22 1980-01-21 Procede de preparation de derives immunoregulateurs de copolymeres de monomeres olefiniques et d'anhydrides polycarboxyliques et nouvelles compositions ainsi obtenues

Country Status (33)

Country Link
US (1) US4255537A (fr)
JP (1) JPS55100322A (fr)
AT (1) AT368172B (fr)
AU (1) AU533497B2 (fr)
BE (1) BE881264A (fr)
CA (1) CA1140852A (fr)
CH (1) CH644874A5 (fr)
DD (1) DD148780A5 (fr)
DE (1) DE3002047A1 (fr)
DK (1) DK23780A (fr)
EG (1) EG14805A (fr)
ES (1) ES487819A0 (fr)
FI (1) FI68060C (fr)
FR (1) FR2446843A1 (fr)
GB (1) GB2040951B (fr)
GR (1) GR68103B (fr)
HU (1) HU184229B (fr)
IE (1) IE49366B1 (fr)
IL (1) IL59172A (fr)
IN (1) IN151745B (fr)
IT (1) IT1193367B (fr)
LU (1) LU82099A1 (fr)
MA (1) MA18705A1 (fr)
MW (1) MW580A1 (fr)
NL (1) NL184900C (fr)
NO (1) NO158807C (fr)
NZ (1) NZ192649A (fr)
OA (1) OA06425A (fr)
PL (1) PL128160B1 (fr)
PT (1) PT70717A (fr)
SE (1) SE449490B (fr)
ZA (1) ZA80330B (fr)
ZM (1) ZM480A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4309413A (en) * 1979-01-22 1982-01-05 Monsanto Company Method of producing immune response by administering polymeric composition
US4397995A (en) * 1980-12-29 1983-08-09 Monsanto Company Polymeric anti-tumor agent and method of preparation
US4508866A (en) * 1981-06-17 1985-04-02 Monsanto Company Polymeric antitumor agent
US4517329A (en) * 1981-06-17 1985-05-14 Monsanto Company Polymeric antitumor agent
US4510285A (en) * 1981-06-17 1985-04-09 Monsanto Company Terpolymeric antitumor agent
US4501847A (en) * 1981-07-09 1985-02-26 Monsanto Company Polymeric antitumor agent
US4514340A (en) * 1982-08-30 1985-04-30 Monsanto Company Cyano-polycarboxylates
US4442298A (en) * 1982-08-30 1984-04-10 Monsanto Company Chemical synthesis of ethylene/maleic anhydride dimer with phenylethyl end group
US4521344A (en) * 1982-08-30 1985-06-04 Monsanto Company Cyano-dicarboxylate
JPS6143124A (ja) * 1984-08-06 1986-03-01 Japan Synthetic Rubber Co Ltd 抗体の製造方法
PT93772A (pt) * 1989-04-17 1991-01-08 Searle & Co Processo para a preparacao de composicoes para o tratamento de neoplasias, contendo um agente anti-neoplastico, por exemplo doxorubicina e um agente protector para reduzir os efeitos secundarios, por exemplo carbetimer
WO2017048719A1 (fr) * 2015-09-14 2017-03-23 Saudi Arabian Oil Company Polymères d'anhydride maléique et procédés de traitement de formations souterraines
EP3350282B1 (fr) 2015-09-14 2020-11-04 Saudi Arabian Oil Company Polymères d'époxyde pendant et procédés de traitement de formations souterraines
EP3535345A1 (fr) 2016-11-04 2019-09-11 Saudi Arabian Oil Company Compositions et procédés d'obturation de canaux d'écoulement en contact avec du ciment durci

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA664326A (en) 1963-06-04 E. Fields Joseph Polymeric electrolyte-containing composition
US2883287A (en) * 1957-01-28 1959-04-21 Monsanto Chemicals Treatment of produce
US3157595A (en) * 1959-09-16 1964-11-17 Monsanto Co Clarification of water with copolymers containing half-amides of olefinic anhydrides
GB1363512A (en) * 1971-03-25 1974-08-14 Ethylene Plastique Sa Adhesives based on copolymer of ethylene and maleic anhydride

Also Published As

Publication number Publication date
IL59172A (en) 1982-12-31
ZM480A1 (en) 1981-06-22
PL221495A1 (fr) 1980-12-01
FR2446843B1 (fr) 1984-03-16
ATA28480A (de) 1982-01-15
MW580A1 (en) 1981-03-11
IN151745B (fr) 1983-07-23
BE881264A (fr) 1980-07-22
MA18705A1 (fr) 1980-10-01
SE449490B (sv) 1987-05-04
ES8102153A1 (es) 1980-12-16
NZ192649A (en) 1985-02-28
CA1140852A (fr) 1983-02-08
NL184900B (nl) 1989-07-03
PT70717A (en) 1980-02-01
ES487819A0 (es) 1980-12-16
NL184900C (nl) 1989-12-01
IL59172A0 (en) 1980-05-30
ZA80330B (en) 1981-03-25
FI68060C (fi) 1985-07-10
JPS55100322A (en) 1980-07-31
IE49366B1 (en) 1985-09-18
CH644874A5 (de) 1984-08-31
IT1193367B (it) 1988-06-15
OA06425A (fr) 1981-07-31
FI800158A (fi) 1980-07-23
JPH0159250B2 (fr) 1989-12-15
AU5477680A (en) 1980-08-07
FI68060B (fi) 1985-03-29
AU533497B2 (en) 1983-12-01
NO158807C (no) 1988-11-02
PL128160B1 (en) 1984-01-31
AT368172B (de) 1982-09-27
LU82099A1 (fr) 1980-08-08
GR68103B (fr) 1981-10-30
HU184229B (en) 1984-07-30
SE8000466L (sv) 1980-09-12
DK23780A (da) 1980-07-23
IT8019343A0 (it) 1980-01-21
GB2040951A (en) 1980-09-03
US4255537A (en) 1981-03-10
DE3002047A1 (de) 1980-07-31
IE800114L (en) 1980-07-22
DD148780A5 (de) 1981-06-10
NL8000334A (nl) 1980-07-24
GB2040951B (en) 1983-01-26
EG14805A (en) 1985-06-30
NO158807B (no) 1988-07-25
NO800137L (no) 1980-07-23

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