FR2446281A1 - Carbamates de mercaptoacyl hydroxy prolines, a action antihypertensive - Google Patents

Carbamates de mercaptoacyl hydroxy prolines, a action antihypertensive

Info

Publication number
FR2446281A1
FR2446281A1 FR8000500A FR8000500A FR2446281A1 FR 2446281 A1 FR2446281 A1 FR 2446281A1 FR 8000500 A FR8000500 A FR 8000500A FR 8000500 A FR8000500 A FR 8000500A FR 2446281 A1 FR2446281 A1 FR 2446281A1
Authority
FR
France
Prior art keywords
mercaptoacyl
carbamates
antihypertensive action
prolines
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8000500A
Other languages
English (en)
French (fr)
Other versions
FR2446281B1 (nl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2446281A1 publication Critical patent/FR2446281A1/fr
Application granted granted Critical
Publication of FR2446281B1 publication Critical patent/FR2446281B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR8000500A 1979-01-15 1980-01-10 Carbamates de mercaptoacyl hydroxy prolines, a action antihypertensive Granted FR2446281A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US317879A 1979-01-15 1979-01-15

Publications (2)

Publication Number Publication Date
FR2446281A1 true FR2446281A1 (fr) 1980-08-08
FR2446281B1 FR2446281B1 (nl) 1984-01-20

Family

ID=21704564

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8000500A Granted FR2446281A1 (fr) 1979-01-15 1980-01-10 Carbamates de mercaptoacyl hydroxy prolines, a action antihypertensive

Country Status (21)

Country Link
JP (2) JPS5598161A (nl)
AT (1) AT364377B (nl)
AU (1) AU526767B2 (nl)
BE (1) BE881153A (nl)
CA (1) CA1138452A (nl)
CH (2) CH646950A5 (nl)
DE (1) DE3001113A1 (nl)
DK (1) DK14980A (nl)
FR (1) FR2446281A1 (nl)
GB (2) GB2040937B (nl)
GR (1) GR73002B (nl)
HU (2) HU182778B (nl)
IE (1) IE49357B1 (nl)
IT (1) IT1140505B (nl)
LU (1) LU82082A1 (nl)
NL (1) NL8000206A (nl)
NO (1) NO800077L (nl)
NZ (1) NZ192522A (nl)
PH (2) PH14946A (nl)
SE (1) SE8000298L (nl)
ZA (1) ZA8035B (nl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0095584A2 (en) * 1982-04-30 1983-12-07 E.R. Squibb & Sons, Inc. Substituted 4-phenoxy and 4-phenylthio prolines

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316905A (en) * 1980-07-01 1982-02-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of various 4-substituted prolines

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
FR2340932A1 (fr) * 1976-02-13 1977-09-09 Squibb & Sons Inc Derives de proline et composes apparentes, utiles pour reduire la tension sanguine
FR2340933A1 (fr) * 1976-02-13 1977-09-09 Squibb & Sons Inc Carboxyalkylacylamino-acides derives de la proline, de l'acide pipecolique et de l'acide azetidine-2-carboxylique

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
FR2340932A1 (fr) * 1976-02-13 1977-09-09 Squibb & Sons Inc Derives de proline et composes apparentes, utiles pour reduire la tension sanguine
FR2340933A1 (fr) * 1976-02-13 1977-09-09 Squibb & Sons Inc Carboxyalkylacylamino-acides derives de la proline, de l'acide pipecolique et de l'acide azetidine-2-carboxylique

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0095584A2 (en) * 1982-04-30 1983-12-07 E.R. Squibb & Sons, Inc. Substituted 4-phenoxy and 4-phenylthio prolines
EP0095584A3 (en) * 1982-04-30 1984-03-28 E.R. Squibb & Sons, Inc. Substituted 4-phenoxy and 4-phenylthio prolines

Also Published As

Publication number Publication date
NO800077L (no) 1980-07-16
GB2040937B (en) 1982-11-24
IE49357B1 (en) 1985-09-18
GB2088875A (en) 1982-06-16
GB2088875B (en) 1983-06-08
LU82082A1 (fr) 1980-04-23
JPH01301656A (ja) 1989-12-05
IT8019209A0 (it) 1980-01-14
HU182778B (en) 1984-03-28
AU5432780A (en) 1980-07-24
CH646690A5 (de) 1984-12-14
JPH0378378B2 (nl) 1991-12-13
DE3001113A1 (de) 1980-07-24
AT364377B (de) 1981-10-12
GB2040937A (en) 1980-09-03
ZA8035B (en) 1980-12-31
ATA19080A (de) 1981-03-15
CA1138452A (en) 1982-12-28
DK14980A (da) 1980-07-16
PH14946A (en) 1982-02-02
SE8000298L (sv) 1980-07-16
HU179621B (en) 1982-11-29
IE800048L (en) 1980-07-15
GR73002B (nl) 1984-01-24
CH646950A5 (de) 1984-12-28
NZ192522A (en) 1982-06-29
IT1140505B (it) 1986-10-01
JPS5598161A (en) 1980-07-25
BE881153A (fr) 1980-07-15
FR2446281B1 (nl) 1984-01-20
NL8000206A (nl) 1980-07-17
JPH0125744B2 (nl) 1989-05-19
PH15318A (en) 1982-11-18
AU526767B2 (en) 1983-01-27

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Legal Events

Date Code Title Description
ST Notification of lapse