FR2340933A1 - Carboxyalkylacylamino-acides derives de la proline, de l'acide pipecolique et de l'acide azetidine-2-carboxylique - Google Patents
Carboxyalkylacylamino-acides derives de la proline, de l'acide pipecolique et de l'acide azetidine-2-carboxyliqueInfo
- Publication number
- FR2340933A1 FR2340933A1 FR7704123A FR7704123A FR2340933A1 FR 2340933 A1 FR2340933 A1 FR 2340933A1 FR 7704123 A FR7704123 A FR 7704123A FR 7704123 A FR7704123 A FR 7704123A FR 2340933 A1 FR2340933 A1 FR 2340933A1
- Authority
- FR
- France
- Prior art keywords
- azetidine
- proline
- acid
- acids derived
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/657,793 US4052511A (en) | 1976-02-13 | 1976-02-13 | Carboxyacylproline derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2340933A1 true FR2340933A1 (fr) | 1977-09-09 |
FR2340933B1 FR2340933B1 (fr) | 1980-04-11 |
Family
ID=24638684
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7704123A Granted FR2340933A1 (fr) | 1976-02-13 | 1977-02-14 | Carboxyalkylacylamino-acides derives de la proline, de l'acide pipecolique et de l'acide azetidine-2-carboxylique |
Country Status (23)
Country | Link |
---|---|
US (3) | US4052511A (fr) |
JP (1) | JPS6058751B2 (fr) |
AT (1) | AT366030B (fr) |
BE (1) | BE851363A (fr) |
CA (1) | CA1104059A (fr) |
CH (1) | CH602633A5 (fr) |
CS (1) | CS197285B2 (fr) |
DD (1) | DD129651A5 (fr) |
DE (1) | DE2704985A1 (fr) |
DK (1) | DK59077A (fr) |
FR (1) | FR2340933A1 (fr) |
GB (1) | GB1570921A (fr) |
HU (1) | HU177144B (fr) |
IE (1) | IE45086B1 (fr) |
NL (1) | NL167688C (fr) |
NO (1) | NO145915C (fr) |
NZ (1) | NZ183222A (fr) |
PH (1) | PH12066A (fr) |
PL (1) | PL106416B1 (fr) |
SE (1) | SE426169B (fr) |
SU (1) | SU694070A3 (fr) |
YU (1) | YU33277A (fr) |
ZA (1) | ZA77564B (fr) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2412537A1 (fr) * | 1977-12-22 | 1979-07-20 | Science Union & Cie | Nouveaux thiobutyramides substitues, leurs procedes d'obtention et leur application pharmaceutique |
FR2434150A1 (fr) * | 1978-08-24 | 1980-03-21 | Yoshitomi Pharmaceutical | Derives d'acides hydroxamiques et medicaments qui en contiennent |
EP0010347A1 (fr) * | 1978-09-05 | 1980-04-30 | American Cyanamid Company | Omega-aroyl(propionyl ou butyryl)-L-prolines substituées, compositions pharmaceutiques les contenant et procédés pour leur préparation |
FR2446281A1 (fr) * | 1979-01-15 | 1980-08-08 | Squibb & Sons Inc | Carbamates de mercaptoacyl hydroxy prolines, a action antihypertensive |
EP0021883A2 (fr) * | 1979-05-30 | 1981-01-07 | Merrell Toraude Et Compagnie | Dérivés d'aminoacides N-acylés et compositions pharmaceutiques les contenant, intermédiaires et produits de départ |
EP0031104A1 (fr) * | 1979-12-13 | 1981-07-01 | Santen Pharmaceutical Co., Ltd. | Composés de thiazolidine, procédés pour leur préparation et compositions pharmaceutiques les contenant |
EP0045161A1 (fr) * | 1980-07-24 | 1982-02-03 | Imperial Chemical Industries Plc | Amides des dérivés de l'acide 4-oxo-5 amidohexanoiques |
EP0053017A1 (fr) * | 1980-11-24 | 1982-06-02 | Imperial Chemical Industries Plc | Dérivés amidiques |
Families Citing this family (91)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3242869A (en) * | 1964-07-15 | 1966-03-29 | Walter D Komhyr | Rectangular-piston pump |
US4199512A (en) * | 1976-05-10 | 1980-04-22 | E. R. Squibb & Sons, Inc. | Compounds for alleviating hypertension |
US4113715A (en) * | 1977-01-17 | 1978-09-12 | E. R. Squibb & Sons, Inc. | Amino acid derivatives |
US4241076A (en) * | 1978-02-21 | 1980-12-23 | E. R. Squibb & Sons, Inc. | Halogenated substituted mercaptoacylamino acids |
US4154935A (en) * | 1978-02-21 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Halogen substituted mercaptoacylamino acids |
US4179568A (en) * | 1978-07-31 | 1979-12-18 | E. R. Squibb & Sons, Inc. | (N-lower alkyl-3,5-dioxo-3-pyrrolidinyl)thioalkanoylpyrrolidine-and piperidine-carboxylic acid compounds |
JPS584711B2 (ja) * | 1978-08-02 | 1983-01-27 | 参天製薬株式会社 | ピロリジン誘導体 |
US4154934A (en) * | 1978-08-11 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Mercaptoacylamino derivatives of heterocyclic carboxylic acids |
US4226775A (en) * | 1979-06-01 | 1980-10-07 | American Cyanamid Company | Substituted thio-substituted benzyl-propionyl-L-prolines |
US4690940A (en) * | 1979-08-14 | 1987-09-01 | University Of Miami | Anti-hypertensive agents |
US4690938A (en) * | 1979-08-14 | 1987-09-01 | University Of Miami | Anti-hypertensive agents |
US4690937A (en) * | 1979-08-14 | 1987-09-01 | University Of Miami | Anti-hypertensive agents |
ZA794723B (en) * | 1978-09-11 | 1980-08-27 | Univ Miami | Anti-hypertensive agents |
US4695577A (en) * | 1979-08-14 | 1987-09-22 | University Of Miami | Anti-hypertensive agents |
US4690939A (en) * | 1979-08-14 | 1987-09-01 | University Of Miami | Anti-hypertensive agents |
US4698356A (en) * | 1979-08-14 | 1987-10-06 | University Of Miami | Anti-hypertensive agents |
US4698355A (en) * | 1979-08-14 | 1987-10-06 | University Of Miami | Anti-hypertensive agents |
US4217359A (en) * | 1979-01-15 | 1980-08-12 | E. R. Squibb & Sons, Inc. | Carbamate derivatives of mercaptoacyl hydroxy prolines |
US4291040A (en) * | 1979-10-22 | 1981-09-22 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of 4-disubstituted prolines and 4-substituted dehydroprolines |
US4499102A (en) * | 1979-12-13 | 1985-02-12 | Santen Pharmaceutical Co., Ltd. | Thiazolidine and pyrrolidine compounds and pharmaceutical compositions containing them |
PT70158A1 (en) * | 1980-03-03 | 1982-03-01 | Univ Miami | Process for preparing anti-hypertensive agents |
US4690936A (en) * | 1980-03-05 | 1987-09-01 | University Of Miami | Anti-hypertensive agents |
US4734420A (en) * | 1980-03-05 | 1988-03-29 | University Of Miami | Anti-hypertensive agents |
AU542211B2 (en) * | 1980-03-07 | 1985-02-14 | Gruppo Lepetit S.P.A. | Mercaptocycloalkyl carbonyl prolines |
US4629787A (en) * | 1980-08-18 | 1986-12-16 | Merck & Co., Inc. | Substituted caprolactam derivatives as antihypertensives |
US4587050A (en) * | 1980-08-18 | 1986-05-06 | Merck & Co., Inc. | Substituted enantholactam derivatives as antihypertensives |
US4344949A (en) * | 1980-10-03 | 1982-08-17 | Warner-Lambert Company | Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
US4311705A (en) * | 1980-10-06 | 1982-01-19 | E. R. Squibb & Sons, Inc. | Carboxyalkanoyl and hydroxycarbamoylalkanoyl derivatives of substituted prolines |
US4409146A (en) * | 1980-10-06 | 1983-10-11 | Merck & Co., Inc. | Substituted caprolactam derivatives as antihypertensives |
US4374847A (en) * | 1980-10-27 | 1983-02-22 | Ciba-Geigy Corporation | 1-Carboxyalkanoylindoline-2-carboxylic acids |
US4390700A (en) * | 1980-11-10 | 1983-06-28 | Ciba-Geigy Corporation | 1-Carboxyazaalkanoyl-tetrahydroquinoline-2-carboxylic acids |
US4462943A (en) * | 1980-11-24 | 1984-07-31 | E. R. Squibb & Sons, Inc. | Carboxyalkyl amino acid derivatives of various substituted prolines |
US4303662A (en) * | 1980-11-24 | 1981-12-01 | E. R. Squibb & Sons, Inc. | Carboxyacyl, mercapto and acylmercapto derivatives of heterobicyclo compounds |
US4321383A (en) * | 1980-11-24 | 1982-03-23 | E. R. Squibb & Sons, Inc. | Heterobicyclo intermediates |
US4401818A (en) * | 1980-12-24 | 1983-08-30 | Ciba-Geigy Corporation | 1-Carboxyalkanoyl-1,2,3,4-tetrahydroquinoline-2-carboxylic acids |
US4479963A (en) * | 1981-02-17 | 1984-10-30 | Ciba-Geigy Corporation | 1-Carboxyalkanoylindoline-2-carboxylic acids |
US4532342A (en) * | 1981-02-20 | 1985-07-30 | Warner-Lambert Company | N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
US4402969A (en) * | 1981-03-23 | 1983-09-06 | Merck & Co., Inc. | Antihypertensive proline derivatives |
US4512979A (en) * | 1981-03-23 | 1985-04-23 | Merck & Co., Inc. | Dipeptides containing thialysine and related amino acids as antihypertensives |
US4587238A (en) * | 1981-07-06 | 1986-05-06 | Merck & Co., Inc. | Substituted caprylolactam derivatives as anti-hypertensives |
US4866087A (en) * | 1982-01-21 | 1989-09-12 | Merck & Co., Inc. | Carboxyalkyl urea compounds and derivatives thereof useful as angiotensin converting enzyme inhibitors and as antihypertensives |
US4483850A (en) * | 1982-05-10 | 1984-11-20 | Merck & Co., Inc. | N-Terminal substituted oligopeptide converting enzyme inhibitors |
US4634716A (en) * | 1982-09-30 | 1987-01-06 | Merck & Co., Inc. | Substituted N-carboxymethyl-aminoacylaminoalkanoic acids useful as antihypertensive agents |
US4499079A (en) * | 1982-11-18 | 1985-02-12 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
US4587234A (en) * | 1982-11-18 | 1986-05-06 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
US4456595A (en) * | 1982-12-06 | 1984-06-26 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy aroly peptides |
GB8311286D0 (en) * | 1983-04-26 | 1983-06-02 | Searle & Co | Carboxyalkyl peptide derivatives |
US4552889A (en) * | 1983-06-09 | 1985-11-12 | Eli Lilly And Company | 3-Mercaptomethyl-2-oxo-1-pyrrolidine acetic acids and use for hypertension |
US4472384A (en) * | 1983-06-15 | 1984-09-18 | Merck & Co., Inc. | Antihypertensive composition |
US4617301A (en) * | 1983-06-22 | 1986-10-14 | Merck & Co., Inc. | Sulfoxide and sulfone derivatives of bicyclic lactams as antihypertensives |
US4558037A (en) * | 1984-06-04 | 1985-12-10 | Merck & Co., Inc. | Cardiovascular composition |
US4939261A (en) * | 1984-06-08 | 1990-07-03 | Ciba-Geigy Corporation | N-substituted butyramide derivatives useful for treatment of conditions responsive to inhibition of enkephalinase |
US5096925A (en) * | 1984-06-08 | 1992-03-17 | Ciba-Geigy Corporation | N-substituted butyramide derivatives |
US4678800A (en) * | 1984-06-15 | 1987-07-07 | Ciba-Geigy Corporation | Gamma-r-glutamoyl derivatives |
US4568489A (en) * | 1984-06-29 | 1986-02-04 | E. R. Squibb & Sons, Inc. | N-Acyl-γ-glutamyl imino and amino acids and esters |
JPS6137764A (ja) * | 1984-07-31 | 1986-02-22 | Suntory Ltd | 抗プロリルエンドペプチダ−ゼ活性を有する新規生理活性化合物 |
US4626545A (en) * | 1984-08-27 | 1986-12-02 | Merck & Co., Inc. | Amino acid derivatives as enzyme inhibitors |
JPH0623190B2 (ja) * | 1985-04-16 | 1994-03-30 | サントリー株式会社 | インヒビタ−活性を有するn−アシルピロリジン誘導体及びその製法並びに用途 |
US5166212A (en) * | 1985-12-06 | 1992-11-24 | Ciba-Geigy Corporation | Certain n-substituted butyramide derivatives |
EP0225292A3 (fr) * | 1985-12-06 | 1988-11-30 | Ciba-Geigy Ag | Certains dérivés de butyramide N-substitués |
US5356890A (en) * | 1988-06-15 | 1994-10-18 | Brigham And Women's Hospital | S-nitroso derivatives of ace inhibitors and the use thereof |
US5025001A (en) * | 1988-06-15 | 1991-06-18 | Brigham And Women's Hospital | S-nitroso derivatives of ACE inhibitors and the use thereof |
US5002964A (en) * | 1988-06-15 | 1991-03-26 | Brigham & Women's Hospital | S-nitrosocaptopril compounds and the use thereof |
US5187183A (en) * | 1988-06-15 | 1993-02-16 | Brigham & Women's Hospital | S-nitroso derivatives of ACE inhibitors and the use thereof |
US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
US6797820B2 (en) | 1999-12-17 | 2004-09-28 | Vicuron Pharmaceuticals Inc. | Succinate compounds, compositions and methods of use and preparation |
AR036053A1 (es) * | 2001-06-15 | 2004-08-04 | Versicor Inc | Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas |
JP4314340B2 (ja) * | 2001-06-15 | 2009-08-12 | ヴィキュロン ファーマシューティカルズ インコーポレイテッド | ピロリジン二環性化合物 |
GB0221169D0 (en) * | 2002-09-12 | 2002-10-23 | Univ Bath | Crystal |
ITMI20041567A1 (it) * | 2004-07-30 | 2004-10-30 | Maycos Italiana Di Comini Miro | "derivati n-acilati di acidi bicarbossilici con amminoacidi e con idrolizzati proteici vegetali e loro applicazione in prodotti cosmetici, dermofarmaceutici e farmaceutici" |
US20070086958A1 (en) * | 2005-10-14 | 2007-04-19 | Medafor, Incorporated | Formation of medically useful gels comprising microporous particles and methods of use |
US20070087061A1 (en) * | 2005-10-14 | 2007-04-19 | Medafor, Incorporated | Method and composition for creating and/or activating a platelet-rich gel by contact with a porous particulate material, for use in wound care, tissue adhesion, or as a matrix for delivery of therapeutic components |
GB0600406D0 (en) * | 2006-01-10 | 2006-02-15 | Univ Bath | Crystal |
US9259535B2 (en) | 2006-06-22 | 2016-02-16 | Excelsior Medical Corporation | Antiseptic cap equipped syringe |
US11229746B2 (en) | 2006-06-22 | 2022-01-25 | Excelsior Medical Corporation | Antiseptic cap |
CN100590117C (zh) * | 2007-08-01 | 2010-02-17 | 潍坊潍泰化工有限公司 | 一种制备3-乙酰硫基-2-甲基-丙酰氯方法 |
JPWO2009057427A1 (ja) * | 2007-10-29 | 2011-03-10 | 宇部興産株式会社 | 第二級カルボン酸化合物及びそれを用いた電解コンデンサ用電解液 |
US9078992B2 (en) | 2008-10-27 | 2015-07-14 | Pursuit Vascular, Inc. | Medical device for applying antimicrobial to proximal end of catheter |
CA2841832C (fr) | 2011-07-12 | 2019-06-04 | Pursuit Vascular, Inc. | Dispositif de distribution d'agent antimicrobien dans catheter transdermique |
JP6546988B2 (ja) | 2014-05-02 | 2019-07-17 | エクセルシオール・メディカル・コーポレイションExcelsior Medical Corporation | 防腐キャップのためのストリップパッケージ |
JP6822978B2 (ja) | 2015-05-08 | 2021-01-27 | アイシーユー・メディカル・インコーポレーテッド | 治療薬のエミッタを受け入れるように構成された医療用コネクタ |
WO2018071717A1 (fr) | 2016-10-14 | 2018-04-19 | Icu Medical, Inc. | Capuchons désinfectants pour raccords médicaux |
WO2018204206A2 (fr) | 2017-05-01 | 2018-11-08 | Icu Medical, Inc. | Raccords de fluide médical et procédés pour fournir des additifs dans des conduites de fluide médical |
US11541221B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Tubing set with antimicrobial properties |
US11517732B2 (en) | 2018-11-07 | 2022-12-06 | Icu Medical, Inc. | Syringe with antimicrobial properties |
US11534595B2 (en) | 2018-11-07 | 2022-12-27 | Icu Medical, Inc. | Device for delivering an antimicrobial composition into an infusion device |
US11541220B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Needleless connector with antimicrobial properties |
US11400195B2 (en) | 2018-11-07 | 2022-08-02 | Icu Medical, Inc. | Peritoneal dialysis transfer set with antimicrobial properties |
EP3883638A1 (fr) | 2018-11-21 | 2021-09-29 | ICU Medical, Inc. | Dispositif antimicrobien comprenant un capuchon avec bague et insert |
CN110615827B (zh) * | 2019-09-10 | 2020-11-03 | 中国海洋大学 | 一种X-Pro结构特异型ACE抑制肽及其制备方法 |
WO2022125474A1 (fr) | 2020-12-07 | 2022-06-16 | Icu Medical, Inc. | Capuchons, systèmes et procédés de dialyse péritonéale |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2627487A (en) * | 1949-01-11 | 1953-02-03 | Nathan L Drake | Insect repellents |
US3335145A (en) * | 1963-03-07 | 1967-08-08 | Reilly Tar & Chem Corp | N-carboxyacyl- and n-carboxyaroylcarboxy piperidines |
-
1976
- 1976-02-13 US US05/657,793 patent/US4052511A/en not_active Expired - Lifetime
-
1977
- 1977-01-31 NZ NZ183222A patent/NZ183222A/xx unknown
- 1977-02-01 ZA ZA770564A patent/ZA77564B/xx unknown
- 1977-02-03 IE IE229/77A patent/IE45086B1/en unknown
- 1977-02-04 PH PH19419A patent/PH12066A/en unknown
- 1977-02-04 CA CA271,135A patent/CA1104059A/fr not_active Expired
- 1977-02-07 DE DE19772704985 patent/DE2704985A1/de not_active Ceased
- 1977-02-08 YU YU00332/77A patent/YU33277A/xx unknown
- 1977-02-11 HU HU77SU940A patent/HU177144B/hu unknown
- 1977-02-11 DD DD7700197347A patent/DD129651A5/xx unknown
- 1977-02-11 DK DK59077A patent/DK59077A/da not_active Application Discontinuation
- 1977-02-11 US US05/767,708 patent/US4086338A/en not_active Expired - Lifetime
- 1977-02-11 SU SU772452053A patent/SU694070A3/ru active
- 1977-02-11 NO NO770465A patent/NO145915C/no unknown
- 1977-02-11 BE BE174887A patent/BE851363A/fr not_active IP Right Cessation
- 1977-02-11 CH CH170477A patent/CH602633A5/xx not_active IP Right Cessation
- 1977-02-11 CS CS77926A patent/CS197285B2/cs unknown
- 1977-02-11 SE SE7701562A patent/SE426169B/xx unknown
- 1977-02-11 US US05/768,003 patent/US4128653A/en not_active Expired - Lifetime
- 1977-02-11 GB GB5745/77A patent/GB1570921A/en not_active Expired
- 1977-02-11 NL NL7701463A patent/NL167688C/xx not_active IP Right Cessation
- 1977-02-12 JP JP52014543A patent/JPS6058751B2/ja not_active Expired
- 1977-02-14 PL PL1977195997A patent/PL106416B1/pl unknown
- 1977-02-14 AT AT0096977A patent/AT366030B/de not_active IP Right Cessation
- 1977-02-14 FR FR7704123A patent/FR2340933A1/fr active Granted
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2412537A1 (fr) * | 1977-12-22 | 1979-07-20 | Science Union & Cie | Nouveaux thiobutyramides substitues, leurs procedes d'obtention et leur application pharmaceutique |
FR2434150A1 (fr) * | 1978-08-24 | 1980-03-21 | Yoshitomi Pharmaceutical | Derives d'acides hydroxamiques et medicaments qui en contiennent |
EP0010347A1 (fr) * | 1978-09-05 | 1980-04-30 | American Cyanamid Company | Omega-aroyl(propionyl ou butyryl)-L-prolines substituées, compositions pharmaceutiques les contenant et procédés pour leur préparation |
FR2446281A1 (fr) * | 1979-01-15 | 1980-08-08 | Squibb & Sons Inc | Carbamates de mercaptoacyl hydroxy prolines, a action antihypertensive |
EP0021883A2 (fr) * | 1979-05-30 | 1981-01-07 | Merrell Toraude Et Compagnie | Dérivés d'aminoacides N-acylés et compositions pharmaceutiques les contenant, intermédiaires et produits de départ |
EP0021883A3 (fr) * | 1979-05-30 | 1981-03-25 | Merrell Toraude Et Compagnie | Dérivés d'aminoacides N-acylés et compositions pharmaceutiques les contenant, intermédiaires et produits de départ |
EP0031104A1 (fr) * | 1979-12-13 | 1981-07-01 | Santen Pharmaceutical Co., Ltd. | Composés de thiazolidine, procédés pour leur préparation et compositions pharmaceutiques les contenant |
EP0045161A1 (fr) * | 1980-07-24 | 1982-02-03 | Imperial Chemical Industries Plc | Amides des dérivés de l'acide 4-oxo-5 amidohexanoiques |
EP0053017A1 (fr) * | 1980-11-24 | 1982-06-02 | Imperial Chemical Industries Plc | Dérivés amidiques |
Also Published As
Publication number | Publication date |
---|---|
HU177144B (en) | 1981-07-28 |
BE851363A (fr) | 1977-08-11 |
PL195997A1 (pl) | 1978-02-27 |
NZ183222A (en) | 1979-07-11 |
AT366030B (de) | 1982-03-10 |
ATA96977A (de) | 1981-07-15 |
DE2704985A1 (de) | 1977-08-18 |
SU694070A3 (ru) | 1979-10-25 |
NL167688C (nl) | 1982-01-18 |
JPS52100461A (en) | 1977-08-23 |
NO145915C (no) | 1982-06-23 |
SE7701562L (sv) | 1977-09-23 |
US4052511A (en) | 1977-10-04 |
PL106416B1 (pl) | 1979-12-31 |
PH12066A (en) | 1978-10-18 |
DK59077A (da) | 1977-08-14 |
NO770465L (no) | 1977-08-16 |
GB1570921A (en) | 1980-07-09 |
US4128653A (en) | 1978-12-05 |
NO145915B (no) | 1982-03-15 |
YU33277A (en) | 1982-08-31 |
NL7701463A (nl) | 1977-08-16 |
NL167688B (nl) | 1981-08-17 |
JPS6058751B2 (ja) | 1985-12-21 |
IE45086L (en) | 1977-08-13 |
IE45086B1 (en) | 1982-06-16 |
FR2340933B1 (fr) | 1980-04-11 |
SE426169B (sv) | 1982-12-13 |
CH602633A5 (fr) | 1978-07-31 |
CS197285B2 (en) | 1980-04-30 |
US4086338A (en) | 1978-04-25 |
AU2189877A (en) | 1978-08-10 |
CA1104059A (fr) | 1981-06-30 |
DD129651A5 (de) | 1978-02-01 |
ZA77564B (en) | 1977-12-28 |
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