IE800048L - Mercaptoacyl hydroxy prolines. - Google Patents

Mercaptoacyl hydroxy prolines.

Info

Publication number
IE800048L
IE800048L IE800048A IE4880A IE800048L IE 800048 L IE800048 L IE 800048L IE 800048 A IE800048 A IE 800048A IE 4880 A IE4880 A IE 4880A IE 800048 L IE800048 L IE 800048L
Authority
IE
Ireland
Prior art keywords
mercaptoacyl
prolines
hydroxy
hydroxy prolines
alkyl
Prior art date
Application number
IE800048A
Other versions
IE49357B1 (en
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IE800048L publication Critical patent/IE800048L/en
Publication of IE49357B1 publication Critical patent/IE49357B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention provides carbamate derivatives of hydroxy prolines which are useful in preparing new carbamate derivatives of mercaptoacyl hydroxy prolines. The compounds of the invention have the formula <IMAGE> wherein each of R0 and R1 is H, alkyl, cycloalkyl, alkyl, propargyl, phenyl or substituted phenyl, or R0 and R1 can form a ring. [GB2088875A]
IE48/80A 1979-01-15 1980-01-10 Derivatives of mercaptoacyl hydroxy prolines and compositions containing them IE49357B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US317879A 1979-01-15 1979-01-15

Publications (2)

Publication Number Publication Date
IE800048L true IE800048L (en) 1980-07-15
IE49357B1 IE49357B1 (en) 1985-09-18

Family

ID=21704564

Family Applications (1)

Application Number Title Priority Date Filing Date
IE48/80A IE49357B1 (en) 1979-01-15 1980-01-10 Derivatives of mercaptoacyl hydroxy prolines and compositions containing them

Country Status (21)

Country Link
JP (2) JPS5598161A (en)
AT (1) AT364377B (en)
AU (1) AU526767B2 (en)
BE (1) BE881153A (en)
CA (1) CA1138452A (en)
CH (2) CH646950A5 (en)
DE (1) DE3001113A1 (en)
DK (1) DK14980A (en)
FR (1) FR2446281A1 (en)
GB (2) GB2040937B (en)
GR (1) GR73002B (en)
HU (2) HU179621B (en)
IE (1) IE49357B1 (en)
IT (1) IT1140505B (en)
LU (1) LU82082A1 (en)
NL (1) NL8000206A (en)
NO (1) NO800077L (en)
NZ (1) NZ192522A (en)
PH (2) PH14946A (en)
SE (1) SE8000298L (en)
ZA (1) ZA8035B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316905A (en) * 1980-07-01 1982-02-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of various 4-substituted prolines
CA1258853A (en) * 1982-04-30 1989-08-29 Rudiger D. Haugwitz Substituted 4-phenoxy prolines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
US4052511A (en) * 1976-02-13 1977-10-04 E. R. Squibb & Sons, Inc. Carboxyacylproline derivatives

Also Published As

Publication number Publication date
NL8000206A (en) 1980-07-17
SE8000298L (en) 1980-07-16
BE881153A (en) 1980-07-15
IE49357B1 (en) 1985-09-18
LU82082A1 (en) 1980-04-23
DK14980A (en) 1980-07-16
AU526767B2 (en) 1983-01-27
JPH0378378B2 (en) 1991-12-13
ZA8035B (en) 1980-12-31
DE3001113A1 (en) 1980-07-24
NO800077L (en) 1980-07-16
GB2040937A (en) 1980-09-03
CA1138452A (en) 1982-12-28
JPH01301656A (en) 1989-12-05
IT8019209A0 (en) 1980-01-14
CH646690A5 (en) 1984-12-14
PH14946A (en) 1982-02-02
IT1140505B (en) 1986-10-01
GB2088875B (en) 1983-06-08
AU5432780A (en) 1980-07-24
ATA19080A (en) 1981-03-15
HU182778B (en) 1984-03-28
JPS5598161A (en) 1980-07-25
CH646950A5 (en) 1984-12-28
JPH0125744B2 (en) 1989-05-19
GB2088875A (en) 1982-06-16
GB2040937B (en) 1982-11-24
FR2446281B1 (en) 1984-01-20
PH15318A (en) 1982-11-18
NZ192522A (en) 1982-06-29
GR73002B (en) 1984-01-24
HU179621B (en) 1982-11-29
AT364377B (en) 1981-10-12
FR2446281A1 (en) 1980-08-08

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