FR2400904A1 - Preparations pour administration vaginale et leur utilisation comme agents provoquant l'ovulation ou comme agents anti-mitotiques - Google Patents
Preparations pour administration vaginale et leur utilisation comme agents provoquant l'ovulation ou comme agents anti-mitotiquesInfo
- Publication number
- FR2400904A1 FR2400904A1 FR7824516A FR7824516A FR2400904A1 FR 2400904 A1 FR2400904 A1 FR 2400904A1 FR 7824516 A FR7824516 A FR 7824516A FR 7824516 A FR7824516 A FR 7824516A FR 2400904 A1 FR2400904 A1 FR 2400904A1
- Authority
- FR
- France
- Prior art keywords
- agents
- vaginal administration
- preparations
- mitotic
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/13—Luteinizing hormone-releasing hormone; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Préparation pour administration vaginale Cette préparation contient, comme ingrédient pharmaceutiquement actif principal un peptide ayant une activité d'hormone libérant l'hormone luteinisante et dont l'absorption est améliorée en ajoutant un acide carboxylique aliphatique aquasoluble ayant 2 à 6 atomes de carbone. Utilisation de cette préparation, comme médicament oestrogène ou anti-mitotique.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52101945A JPS6047249B2 (ja) | 1977-08-24 | 1977-08-24 | 膣投与剤 |
JP3933778A JPS54132221A (en) | 1978-04-03 | 1978-04-03 | Water-based medicine for vaginal administration |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2400904A1 true FR2400904A1 (fr) | 1979-03-23 |
FR2400904B1 FR2400904B1 (fr) | 1982-07-30 |
Family
ID=26378690
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7824516A Granted FR2400904A1 (fr) | 1977-08-24 | 1978-08-23 | Preparations pour administration vaginale et leur utilisation comme agents provoquant l'ovulation ou comme agents anti-mitotiques |
Country Status (8)
Country | Link |
---|---|
US (1) | US4211769A (fr) |
AU (1) | AU517349B2 (fr) |
CA (1) | CA1112570A (fr) |
CH (1) | CH634992A5 (fr) |
DE (1) | DE2836631A1 (fr) |
FR (1) | FR2400904A1 (fr) |
GB (1) | GB2003386B (fr) |
IT (1) | IT1098199B (fr) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2465486A1 (fr) * | 1979-09-21 | 1981-03-27 | Roussel Uclaf | Nouvelle application utilisant la lh-rh ou des agonistes |
EP0052510A2 (fr) * | 1980-11-18 | 1982-05-26 | Syntex (U.S.A.) Inc. | Microencapsulation de polypeptides hydrosolubles |
EP0067513A2 (fr) * | 1981-05-14 | 1982-12-22 | Takeda Chemical Industries, Ltd. | Préparations pharmaceutiques contenant du TRH ou son analogue |
EP0130409A2 (fr) * | 1983-06-07 | 1985-01-09 | Takeda Chemical Industries, Ltd. | Corps composite à libération lente et procédé de sa préparation |
Families Citing this family (87)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5389613A (en) * | 1979-09-21 | 1995-02-14 | Roussel Uclaf | Method of treating prostate adenocarcinoma, prostate benign hypertrophia and endometriosis |
DE3165535D1 (en) * | 1980-06-02 | 1984-09-20 | Andrew Victor Schally | Lh-rh antagonists |
US4675189A (en) * | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
JPS59139315A (ja) * | 1983-01-31 | 1984-08-10 | Taisho Pharmaceut Co Ltd | クリ−ム剤 |
GB8308330D0 (en) * | 1983-03-25 | 1983-05-05 | Crighton D B | Immunogenic compositions |
US4801475A (en) * | 1984-08-23 | 1989-01-31 | Gregory Halpern | Method of hydrophilic coating of plastics |
HU193607B (en) * | 1985-07-18 | 1987-11-30 | Innofinance Altalanos Innovaci | Process for production of sexual products applyable for natural or artificial insemination for mammates |
US4663233A (en) * | 1985-10-24 | 1987-05-05 | Universal High Technologies | Lens with hydrophilic coating |
US4746504A (en) * | 1986-03-14 | 1988-05-24 | Bio-Technology General Corp. | Heavy metal salts of hyaluronic acid and their use as antimicrobial agents |
WO1987005517A1 (fr) * | 1986-03-14 | 1987-09-24 | Bio-Technology General Corp. | Sels de metaux lourds de l'acide hyaluronique utiles en tant qu'agents antimicrobiens |
US4784991A (en) * | 1986-03-14 | 1988-11-15 | Bio-Technology General Corp. | Heavy metal salts of hyaluronic acid and their use as antimicrobial agents |
AU609765B2 (en) * | 1986-11-18 | 1991-05-09 | Senetek Plc | Method for inducing vaginal lubrication |
US4897268A (en) * | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
DE3928677C2 (de) * | 1989-08-30 | 1998-05-14 | Kimberly Clark Gmbh | Tampon für medizinische oder hygienische Zwecke sowie Verfahren zu seiner Herstellung |
JP2997488B2 (ja) * | 1989-12-25 | 2000-01-11 | 興研株式会社 | 腫瘍細胞増殖抑制剤 |
CA2070061C (fr) * | 1991-06-07 | 2004-02-10 | Shigeyuki Takama | Composition pharmaceutique renfermant des polypeptides physiologiquement actives |
EP0527241B1 (fr) * | 1991-07-15 | 1994-03-16 | Artesan Pharma Gesellschaft mit beschränkter Haftung | L'utilisation d'acide ascorbique pour la préparation d'un médicament pour utilisation dans la région génitale |
US5518730A (en) | 1992-06-03 | 1996-05-21 | Fuisz Technologies Ltd. | Biodegradable controlled release flash flow melt-spun delivery system |
US6582728B1 (en) * | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
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US6024090A (en) * | 1993-01-29 | 2000-02-15 | Aradigm Corporation | Method of treating a diabetic patient by aerosolized administration of insulin lispro |
US6051256A (en) * | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
CZ295827B6 (cs) | 1994-03-07 | 2005-11-16 | Nektar Therapeutics | Způsob aerosolizace dávky inzulinu, inzulinový přípravek a jeho použití |
US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
US6428771B1 (en) * | 1995-05-15 | 2002-08-06 | Pharmaceutical Discovery Corporation | Method for drug delivery to the pulmonary system |
US20030203036A1 (en) | 2000-03-17 | 2003-10-30 | Gordon Marc S. | Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients |
US6309623B1 (en) | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
RU2230550C2 (ru) * | 1998-01-16 | 2004-06-20 | Такеда Кемикал Индастриз, Лтд. | Композиции длительного высвобождения, способ их получения и применение |
JP4713798B2 (ja) * | 1999-06-29 | 2011-06-29 | マンカインド コーポレイション | ペプチドおよびタンパク質の薬学的因子の精製および安定化 |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
US7442388B2 (en) | 2000-05-10 | 2008-10-28 | Weers Jeffry G | Phospholipid-based powders for drug delivery |
US8404217B2 (en) | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
US7575761B2 (en) | 2000-06-30 | 2009-08-18 | Novartis Pharma Ag | Spray drying process control of drying kinetics |
WO2002055101A2 (fr) * | 2000-12-21 | 2002-07-18 | Inhale Therapeutic Syst | Compositions de recepteur de l'interleukine 4 en poudre stables au stockage |
SI1458360T1 (sl) | 2001-12-19 | 2011-08-31 | Novartis Ag | Pulmonalno dajanje aminoglikozidov |
EP1494732B1 (fr) | 2002-03-20 | 2008-01-30 | MannKind Corporation | Appareil d'inhalation |
DE60323734D1 (de) * | 2002-03-21 | 2008-11-06 | Bifodan As | Lactobacillus-stämme |
GB0216562D0 (en) | 2002-04-25 | 2002-08-28 | Bradford Particle Design Ltd | Particulate materials |
US9339459B2 (en) | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
US8088726B2 (en) * | 2002-06-25 | 2012-01-03 | Takeda Pharmaceutical Company Limited | Process for producing sustained-release composition |
AU2003266142A1 (en) * | 2002-09-12 | 2004-04-30 | Biosyn, Inc. | Mucus formulation for mucosal surfaces and uses thereof |
US7338171B2 (en) * | 2003-10-27 | 2008-03-04 | Jen-Chuen Hsieh | Method and apparatus for visual drive control |
ES2584867T3 (es) * | 2004-01-12 | 2016-09-29 | Mannkind Corporation | Un método que reduce los niveles séricos de proinsulina en diabéticos de tipo 2 |
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ATE433746T1 (de) * | 2004-03-12 | 2009-07-15 | Biodel Inc | Insulinzusammensetzungen mit verbesserter wirkstoffabsorption |
US20080090753A1 (en) | 2004-03-12 | 2008-04-17 | Biodel, Inc. | Rapid Acting Injectable Insulin Compositions |
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WO2007041481A1 (fr) * | 2005-09-29 | 2007-04-12 | Biodel, Inc. | Preparations d'insuline a action rapide et prolongee |
US7713929B2 (en) | 2006-04-12 | 2010-05-11 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
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US20090175840A1 (en) * | 2008-01-04 | 2009-07-09 | Biodel, Inc. | Insulin formulations for insulin release as a function of tissue glucose levels |
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EP2496295A1 (fr) | 2009-11-03 | 2012-09-12 | MannKind Corporation | Appareil et méthode de simulation d'efforts d'inhalation |
DE102010015350A1 (de) | 2010-04-16 | 2011-10-20 | Michael Zimmermann | Vaginalapplikator |
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WO2012174472A1 (fr) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | Microparticules de dicétopipérazine de capacité élevée |
BR112014009686A2 (pt) | 2011-10-24 | 2018-08-07 | Mannkind Corp | composição analgésica inalável, pó seco e método para tratar dor |
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AU2015277613A1 (en) * | 2014-06-16 | 2016-12-08 | Zoetis Services Llc | Intravaginal formulations comprising GnRH |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
GB201501302D0 (en) | 2015-01-27 | 2015-03-11 | Ostara Biomedical Ltd | Embryo implantation |
GB201517523D0 (en) | 2015-10-05 | 2015-11-18 | Ostara Biomedical Ltd | Methods and compositions for managing reproduction |
US20200121589A1 (en) * | 2017-06-22 | 2020-04-23 | Viramal Limited | Compositions for drug delivery and methods of use thereof |
IL258017B (en) * | 2018-03-11 | 2019-10-31 | Aquafit Intimate Ltd | Cervical device and its uses |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3835108A (en) * | 1972-02-15 | 1974-09-10 | American Home Prod | Process for preparing the releasing hormone of luteinizing hormone(lh)and of follicle stimulating hormone(fsh),salts and compositions thereof,and intermediates therefor |
US3917825A (en) * | 1972-10-12 | 1975-11-04 | Takeda Chemical Industries Ltd | Preparation for rectal or vaginal administration containing LH-RH or its analogs |
GB1454105A (en) * | 1972-11-04 | 1976-10-27 | Hoechst Ag | Preparation containing luteinizing hormone-releasing factor |
-
1978
- 1978-08-17 US US05/934,594 patent/US4211769A/en not_active Expired - Lifetime
- 1978-08-22 CH CH887778A patent/CH634992A5/de not_active IP Right Cessation
- 1978-08-22 DE DE19782836631 patent/DE2836631A1/de not_active Withdrawn
- 1978-08-23 FR FR7824516A patent/FR2400904A1/fr active Granted
- 1978-08-23 AU AU39183/78A patent/AU517349B2/en not_active Expired
- 1978-08-23 CA CA309,894A patent/CA1112570A/fr not_active Expired
- 1978-08-23 IT IT26956/78A patent/IT1098199B/it active
- 1978-08-24 GB GB7834426A patent/GB2003386B/en not_active Expired
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3835108A (en) * | 1972-02-15 | 1974-09-10 | American Home Prod | Process for preparing the releasing hormone of luteinizing hormone(lh)and of follicle stimulating hormone(fsh),salts and compositions thereof,and intermediates therefor |
US3917825A (en) * | 1972-10-12 | 1975-11-04 | Takeda Chemical Industries Ltd | Preparation for rectal or vaginal administration containing LH-RH or its analogs |
GB1454105A (en) * | 1972-11-04 | 1976-10-27 | Hoechst Ag | Preparation containing luteinizing hormone-releasing factor |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2465486A1 (fr) * | 1979-09-21 | 1981-03-27 | Roussel Uclaf | Nouvelle application utilisant la lh-rh ou des agonistes |
EP0052510A2 (fr) * | 1980-11-18 | 1982-05-26 | Syntex (U.S.A.) Inc. | Microencapsulation de polypeptides hydrosolubles |
EP0052510A3 (en) * | 1980-11-18 | 1982-09-08 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble polypeptides |
EP0067513A2 (fr) * | 1981-05-14 | 1982-12-22 | Takeda Chemical Industries, Ltd. | Préparations pharmaceutiques contenant du TRH ou son analogue |
EP0067513A3 (en) * | 1981-05-14 | 1983-10-05 | Takeda Chemical Industries, Ltd. | Pharmaceutical preparations containing trh or its analogue |
EP0130409A2 (fr) * | 1983-06-07 | 1985-01-09 | Takeda Chemical Industries, Ltd. | Corps composite à libération lente et procédé de sa préparation |
EP0130409A3 (fr) * | 1983-06-07 | 1986-07-02 | Takeda Chemical Industries, Ltd. | Corps composite à libération lente et procédé de sa préparation |
Also Published As
Publication number | Publication date |
---|---|
AU3918378A (en) | 1980-02-28 |
CH634992A5 (de) | 1983-03-15 |
US4211769A (en) | 1980-07-08 |
CA1112570A (fr) | 1981-11-17 |
GB2003386A (en) | 1979-03-14 |
FR2400904B1 (fr) | 1982-07-30 |
IT7826956A0 (it) | 1978-08-23 |
IT1098199B (it) | 1985-09-07 |
AU517349B2 (en) | 1981-07-23 |
DE2836631A1 (de) | 1979-03-08 |
GB2003386B (en) | 1982-06-16 |
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