FR2400904A1 - Preparations pour administration vaginale et leur utilisation comme agents provoquant l'ovulation ou comme agents anti-mitotiques - Google Patents

Preparations pour administration vaginale et leur utilisation comme agents provoquant l'ovulation ou comme agents anti-mitotiques

Info

Publication number
FR2400904A1
FR2400904A1 FR7824516A FR7824516A FR2400904A1 FR 2400904 A1 FR2400904 A1 FR 2400904A1 FR 7824516 A FR7824516 A FR 7824516A FR 7824516 A FR7824516 A FR 7824516A FR 2400904 A1 FR2400904 A1 FR 2400904A1
Authority
FR
France
Prior art keywords
agents
vaginal administration
preparations
mitotic
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7824516A
Other languages
English (en)
Other versions
FR2400904B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP52101945A external-priority patent/JPS6047249B2/ja
Priority claimed from JP3933778A external-priority patent/JPS54132221A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FR2400904A1 publication Critical patent/FR2400904A1/fr
Application granted granted Critical
Publication of FR2400904B1 publication Critical patent/FR2400904B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Préparation pour administration vaginale Cette préparation contient, comme ingrédient pharmaceutiquement actif principal un peptide ayant une activité d'hormone libérant l'hormone luteinisante et dont l'absorption est améliorée en ajoutant un acide carboxylique aliphatique aquasoluble ayant 2 à 6 atomes de carbone. Utilisation de cette préparation, comme médicament oestrogène ou anti-mitotique.
FR7824516A 1977-08-24 1978-08-23 Preparations pour administration vaginale et leur utilisation comme agents provoquant l'ovulation ou comme agents anti-mitotiques Granted FR2400904A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP52101945A JPS6047249B2 (ja) 1977-08-24 1977-08-24 膣投与剤
JP3933778A JPS54132221A (en) 1978-04-03 1978-04-03 Water-based medicine for vaginal administration

Publications (2)

Publication Number Publication Date
FR2400904A1 true FR2400904A1 (fr) 1979-03-23
FR2400904B1 FR2400904B1 (fr) 1982-07-30

Family

ID=26378690

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7824516A Granted FR2400904A1 (fr) 1977-08-24 1978-08-23 Preparations pour administration vaginale et leur utilisation comme agents provoquant l'ovulation ou comme agents anti-mitotiques

Country Status (8)

Country Link
US (1) US4211769A (fr)
AU (1) AU517349B2 (fr)
CA (1) CA1112570A (fr)
CH (1) CH634992A5 (fr)
DE (1) DE2836631A1 (fr)
FR (1) FR2400904A1 (fr)
GB (1) GB2003386B (fr)
IT (1) IT1098199B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2465486A1 (fr) * 1979-09-21 1981-03-27 Roussel Uclaf Nouvelle application utilisant la lh-rh ou des agonistes
EP0052510A2 (fr) * 1980-11-18 1982-05-26 Syntex (U.S.A.) Inc. Microencapsulation de polypeptides hydrosolubles
EP0067513A2 (fr) * 1981-05-14 1982-12-22 Takeda Chemical Industries, Ltd. Préparations pharmaceutiques contenant du TRH ou son analogue
EP0130409A2 (fr) * 1983-06-07 1985-01-09 Takeda Chemical Industries, Ltd. Corps composite à libération lente et procédé de sa préparation

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5389613A (en) * 1979-09-21 1995-02-14 Roussel Uclaf Method of treating prostate adenocarcinoma, prostate benign hypertrophia and endometriosis
DE3165535D1 (en) * 1980-06-02 1984-09-20 Andrew Victor Schally Lh-rh antagonists
US4675189A (en) * 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
JPS59139315A (ja) * 1983-01-31 1984-08-10 Taisho Pharmaceut Co Ltd クリ−ム剤
GB8308330D0 (en) * 1983-03-25 1983-05-05 Crighton D B Immunogenic compositions
US4801475A (en) * 1984-08-23 1989-01-31 Gregory Halpern Method of hydrophilic coating of plastics
HU193607B (en) * 1985-07-18 1987-11-30 Innofinance Altalanos Innovaci Process for production of sexual products applyable for natural or artificial insemination for mammates
US4663233A (en) * 1985-10-24 1987-05-05 Universal High Technologies Lens with hydrophilic coating
US4746504A (en) * 1986-03-14 1988-05-24 Bio-Technology General Corp. Heavy metal salts of hyaluronic acid and their use as antimicrobial agents
WO1987005517A1 (fr) * 1986-03-14 1987-09-24 Bio-Technology General Corp. Sels de metaux lourds de l'acide hyaluronique utiles en tant qu'agents antimicrobiens
US4784991A (en) * 1986-03-14 1988-11-15 Bio-Technology General Corp. Heavy metal salts of hyaluronic acid and their use as antimicrobial agents
AU609765B2 (en) * 1986-11-18 1991-05-09 Senetek Plc Method for inducing vaginal lubrication
US4897268A (en) * 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
DE3928677C2 (de) * 1989-08-30 1998-05-14 Kimberly Clark Gmbh Tampon für medizinische oder hygienische Zwecke sowie Verfahren zu seiner Herstellung
JP2997488B2 (ja) * 1989-12-25 2000-01-11 興研株式会社 腫瘍細胞増殖抑制剤
CA2070061C (fr) * 1991-06-07 2004-02-10 Shigeyuki Takama Composition pharmaceutique renfermant des polypeptides physiologiquement actives
EP0527241B1 (fr) * 1991-07-15 1994-03-16 Artesan Pharma Gesellschaft mit beschränkter Haftung L'utilisation d'acide ascorbique pour la préparation d'un médicament pour utilisation dans la région génitale
US5518730A (en) 1992-06-03 1996-05-21 Fuisz Technologies Ltd. Biodegradable controlled release flash flow melt-spun delivery system
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
KR100291620B1 (ko) 1992-09-29 2001-10-24 추후제출 부갑상선호르몬의활성단편의폐를통한전달방법
US7448375B2 (en) 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US6051256A (en) * 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
CZ295827B6 (cs) 1994-03-07 2005-11-16 Nektar Therapeutics Způsob aerosolizace dávky inzulinu, inzulinový přípravek a jeho použití
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US6428771B1 (en) * 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
RU2230550C2 (ru) * 1998-01-16 2004-06-20 Такеда Кемикал Индастриз, Лтд. Композиции длительного высвобождения, способ их получения и применение
JP4713798B2 (ja) * 1999-06-29 2011-06-29 マンカインド コーポレイション ペプチドおよびタンパク質の薬学的因子の精製および安定化
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US7442388B2 (en) 2000-05-10 2008-10-28 Weers Jeffry G Phospholipid-based powders for drug delivery
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
WO2002055101A2 (fr) * 2000-12-21 2002-07-18 Inhale Therapeutic Syst Compositions de recepteur de l'interleukine 4 en poudre stables au stockage
SI1458360T1 (sl) 2001-12-19 2011-08-31 Novartis Ag Pulmonalno dajanje aminoglikozidov
EP1494732B1 (fr) 2002-03-20 2008-01-30 MannKind Corporation Appareil d'inhalation
DE60323734D1 (de) * 2002-03-21 2008-11-06 Bifodan As Lactobacillus-stämme
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US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
US8088726B2 (en) * 2002-06-25 2012-01-03 Takeda Pharmaceutical Company Limited Process for producing sustained-release composition
AU2003266142A1 (en) * 2002-09-12 2004-04-30 Biosyn, Inc. Mucus formulation for mucosal surfaces and uses thereof
US7338171B2 (en) * 2003-10-27 2008-03-04 Jen-Chuen Hsieh Method and apparatus for visual drive control
ES2584867T3 (es) * 2004-01-12 2016-09-29 Mannkind Corporation Un método que reduce los niveles séricos de proinsulina en diabéticos de tipo 2
JP4601627B2 (ja) * 2004-01-16 2010-12-22 バイオデル， インコーポレイテッド 舌下薬物送達デバイス
ATE433746T1 (de) * 2004-03-12 2009-07-15 Biodel Inc Insulinzusammensetzungen mit verbesserter wirkstoffabsorption
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
KR101273120B1 (ko) 2004-08-20 2013-06-13 맨카인드 코포레이션 다이케토피페라진 합성의 촉매 작용
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BRPI0707991B8 (pt) 2006-02-22 2021-05-25 Mannkind Corp métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3835108A (en) * 1972-02-15 1974-09-10 American Home Prod Process for preparing the releasing hormone of luteinizing hormone(lh)and of follicle stimulating hormone(fsh),salts and compositions thereof,and intermediates therefor
US3917825A (en) * 1972-10-12 1975-11-04 Takeda Chemical Industries Ltd Preparation for rectal or vaginal administration containing LH-RH or its analogs
GB1454105A (en) * 1972-11-04 1976-10-27 Hoechst Ag Preparation containing luteinizing hormone-releasing factor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3835108A (en) * 1972-02-15 1974-09-10 American Home Prod Process for preparing the releasing hormone of luteinizing hormone(lh)and of follicle stimulating hormone(fsh),salts and compositions thereof,and intermediates therefor
US3917825A (en) * 1972-10-12 1975-11-04 Takeda Chemical Industries Ltd Preparation for rectal or vaginal administration containing LH-RH or its analogs
GB1454105A (en) * 1972-11-04 1976-10-27 Hoechst Ag Preparation containing luteinizing hormone-releasing factor

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2465486A1 (fr) * 1979-09-21 1981-03-27 Roussel Uclaf Nouvelle application utilisant la lh-rh ou des agonistes
EP0052510A2 (fr) * 1980-11-18 1982-05-26 Syntex (U.S.A.) Inc. Microencapsulation de polypeptides hydrosolubles
EP0052510A3 (en) * 1980-11-18 1982-09-08 Syntex (U.S.A.) Inc. Microencapsulation of water soluble polypeptides
EP0067513A2 (fr) * 1981-05-14 1982-12-22 Takeda Chemical Industries, Ltd. Préparations pharmaceutiques contenant du TRH ou son analogue
EP0067513A3 (en) * 1981-05-14 1983-10-05 Takeda Chemical Industries, Ltd. Pharmaceutical preparations containing trh or its analogue
EP0130409A2 (fr) * 1983-06-07 1985-01-09 Takeda Chemical Industries, Ltd. Corps composite à libération lente et procédé de sa préparation
EP0130409A3 (fr) * 1983-06-07 1986-07-02 Takeda Chemical Industries, Ltd. Corps composite à libération lente et procédé de sa préparation

Also Published As

Publication number Publication date
AU3918378A (en) 1980-02-28
CH634992A5 (de) 1983-03-15
US4211769A (en) 1980-07-08
CA1112570A (fr) 1981-11-17
GB2003386A (en) 1979-03-14
FR2400904B1 (fr) 1982-07-30
IT7826956A0 (it) 1978-08-23
IT1098199B (it) 1985-09-07
AU517349B2 (en) 1981-07-23
DE2836631A1 (de) 1979-03-08
GB2003386B (en) 1982-06-16

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