FR2362397A1 - Procede radio-immunologique et dispositif servant a determiner les antigenes - Google Patents

Procede radio-immunologique et dispositif servant a determiner les antigenes

Info

Publication number
FR2362397A1
FR2362397A1 FR7723974A FR7723974A FR2362397A1 FR 2362397 A1 FR2362397 A1 FR 2362397A1 FR 7723974 A FR7723974 A FR 7723974A FR 7723974 A FR7723974 A FR 7723974A FR 2362397 A1 FR2362397 A1 FR 2362397A1
Authority
FR
France
Prior art keywords
radio
immunological method
determining antigens
antibody
antigens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7723974A
Other languages
English (en)
Other versions
FR2362397B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oesterreichisches Institut fuer Haemoderivate
Original Assignee
Immuno AG
Immuno AG fuer Chemisch Medizinische Produkte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno AG, Immuno AG fuer Chemisch Medizinische Produkte filed Critical Immuno AG
Publication of FR2362397A1 publication Critical patent/FR2362397A1/fr
Application granted granted Critical
Publication of FR2362397B1 publication Critical patent/FR2362397B1/fr
Granted legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/804Radioisotope, e.g. radioimmunoassay
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808Automated or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • Y10S436/809Multifield plates or multicontainer arrays
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/82Hepatitis associated antigens and antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne un procédé radio-immunologique et un dispositif servant à déterminer les antigènes. Ce dispositif comprend une plaque de micro-titrage 1 présentant une pluralité d'évidements destinés à recevoir des plaquettes 4, 4', 4" solidaires d'un montant de retenue 3 au moyen de pièces de retenue 5, 5', 5". L'échantillon à analyser pour sa teneur en anticorps ou en antigènes est mélangé à un anticorps repéré radioactivement puis on met au contact dudit liquide de l'échantillon un support fixe tel que 4, comportant un antigène non radioactif, puis après lavage dudit support 4, on détermine son taux de radioactivité. Ce procédé s'applique notamment aux recherches de cancers.
FR7723974A 1976-08-20 1977-08-03 Procede radio-immunologique et dispositif servant a determiner les antigenes Granted FR2362397A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT618576A AT343822B (de) 1976-08-20 1976-08-20 Radioimmunologisches verfahren und einrichtung zur bestimmung von antigenen

Publications (2)

Publication Number Publication Date
FR2362397A1 true FR2362397A1 (fr) 1978-03-17
FR2362397B1 FR2362397B1 (fr) 1980-02-22

Family

ID=3583732

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7723974A Granted FR2362397A1 (fr) 1976-08-20 1977-08-03 Procede radio-immunologique et dispositif servant a determiner les antigenes

Country Status (16)

Country Link
US (1) US4276259A (fr)
AT (1) AT343822B (fr)
BE (1) BE857668A (fr)
CA (1) CA1098441A (fr)
CH (1) CH636258A5 (fr)
DE (1) DE2734118C3 (fr)
DK (1) DK151398C (fr)
ES (1) ES461731A1 (fr)
FI (1) FI65861C (fr)
FR (1) FR2362397A1 (fr)
GB (1) GB1562957A (fr)
IT (1) IT1086008B (fr)
LU (1) LU77986A1 (fr)
NL (1) NL7708871A (fr)
NO (1) NO152670C (fr)
SE (1) SE441868B (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2367286A1 (fr) * 1976-10-07 1978-05-05 Mochida Pharm Co Ltd Nouveau procede et reactifs de dosage immunochimique de substances physiologiquement actives
FR2377629A1 (fr) * 1977-01-14 1978-08-11 Suovaniemi Finnpipette Piece moulee pour appareils utilises pour les dosages immunologiques et les reactions enzymatiques
FR2383446A1 (fr) * 1977-03-11 1978-10-06 Abbott Lab Reactifs et procedes pour la mise en evidence de l'anticorps antinoyaux de dane
FR2459482A1 (fr) * 1979-06-14 1981-01-09 Abbott Lab Procedes et reactifs pour la detection simultanee de differents marqueurs de l'hepatite
EP0087899A2 (fr) * 1982-03-03 1983-09-07 Becton Dickinson and Company Dispositif d'examen à récipients multiples pour essais immunologiques

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0146654A3 (fr) * 1980-06-20 1986-08-20 Unilever Plc Procédé et dispositif pour la réalisation d'essais à liaison spécifique
GB2107053A (en) * 1980-06-20 1983-04-20 Unilever Plc Processes and apparatus for carrying out specific binding assays
US4486540A (en) * 1980-07-18 1984-12-04 Science Research Center, Inc. Identification of reagins in the blood serum of allergen sensitized vertebrates
US4696907A (en) * 1980-07-18 1987-09-29 Science Research Center, Inc. Identification of reagins in the blood serum of allergen sensitized vertebrates
US4459360A (en) * 1981-10-05 1984-07-10 Mast Medical Industries, Ltd. Multiple-component binding assay system and method of making and using it
DE3416933A1 (de) * 1984-05-04 1985-11-07 Dora 1000 Berlin Köhler Mit antigenen oder antikoerpern beschichteter traeger
JPH0823558B2 (ja) * 1984-11-27 1996-03-06 オ−ジエニクス リミテツド 検定装置
US4940670A (en) * 1986-01-24 1990-07-10 Rhodes Buck A Method for compounding and testing patient specific monoclonal antibodies and monoclonal antibody fragments for in vivo use
GB2188418A (en) * 1986-03-27 1987-09-30 Gen Biolog Corp Assay tray assembly
US4891321A (en) * 1987-10-21 1990-01-02 Hubscher Thomas T Apparatus for performing determinations of immune reactants in biological fluids
AT394114B (de) * 1989-07-13 1992-02-10 Immuno Ag Verfahren zur bestimmung von antigenen und/oder antikoerpern in menschlichen koerperfluessigkeiten sowie set zur durchfuehrung des verfahrens
US5319436A (en) * 1992-05-28 1994-06-07 Packard Instrument Company, Inc. Microplate farming wells with transparent bottom walls for assays using light measurements
DK0576090T3 (da) * 1992-06-22 2001-11-12 Packard Instr Bv Klæbende plastscintillator
US5244788A (en) * 1992-07-01 1993-09-14 Hubscher Thomas T Method and apparatus for performing determinations of immune rectants in biological fluids
US5512753A (en) * 1994-06-08 1996-04-30 Packard Instrument, B.V. Scintillation counting system using scintillator capsules
SE9402518D0 (sv) * 1994-07-18 1994-07-18 Pharmacia Biotech Ab Processing system
US6229603B1 (en) 1997-06-02 2001-05-08 Aurora Biosciences Corporation Low background multi-well plates with greater than 864 wells for spectroscopic measurements
US6426050B1 (en) 1997-05-16 2002-07-30 Aurora Biosciences Corporation Multi-well platforms, caddies, lids and combinations thereof
US5910287A (en) * 1997-06-03 1999-06-08 Aurora Biosciences Corporation Low background multi-well plates with greater than 864 wells for fluorescence measurements of biological and biochemical samples
US6063338A (en) 1997-06-02 2000-05-16 Aurora Biosciences Corporation Low background multi-well plates and platforms for spectroscopic measurements
US6171780B1 (en) 1997-06-02 2001-01-09 Aurora Biosciences Corporation Low fluorescence assay platforms and related methods for drug discovery
US6517781B1 (en) * 1997-06-02 2003-02-11 Aurora Biosciences Corporation Low fluorescence assay platforms and related methods for drug discovery
US6861035B2 (en) * 1998-02-24 2005-03-01 Aurora Discovery, Inc. Multi-well platforms, caddies, lids and combinations thereof
DE29803626U1 (de) * 1998-03-03 1998-05-07 Pache, Wolfgang, 79294 Sölden Pinplatte
US7005029B2 (en) * 1999-10-26 2006-02-28 Nalge Nunc International Corporation Method of making a multi-well test plate having adhesively secured transparent bottom panel
ITCZ20020002A1 (it) * 2002-04-11 2003-10-13 Parco Scient E Tecnologico Del Dispositivo e metodo per il rilevamento simultaneo di differenti anticorpi e antigeni in campioni clinici, alimentari ed ambientali
US20040043398A1 (en) * 2002-04-15 2004-03-04 Demetrio Sanchez-Martinez Use of the multipin platform as anchor device
EP1641555B1 (fr) 2003-04-30 2020-12-02 Nexus Biosystems, Inc. Plaque multi-puits pour stockage a densite elevee et plate-forme de dosage
US20050173059A1 (en) * 2004-02-11 2005-08-11 Nalge Nunc International Corporation Methods of making a multi-well test plate having an adhesively secured transparent bottom panel
WO2006116708A2 (fr) * 2005-04-28 2006-11-02 Hitachi Chemical Research Center, Inc. Procede permettant de reduire la consommation de reactifs dans des reactions sur microplaque
GB0609612D0 (en) * 2006-05-15 2006-06-21 Glaxosmithkline Biolog Sa Detection method and kit
JP5775004B2 (ja) 2009-03-03 2015-09-09 アクセス メディカル システムズ,リミティド 高感度蛍光分析のための検出システム及び方法
JP6010110B2 (ja) 2011-04-20 2016-10-19 アクセス メディカル システムズ,リミティド 発光重合体の反復増幅
RU2013150683A (ru) * 2011-04-21 2015-05-27 Университа Дегли Студи Дел Молисе Устройство, способ и набор для выявления различных маркеров в разных клеточных или молекулярных образцах и их количественной оценки
US8569075B2 (en) * 2011-09-14 2013-10-29 Atomic Energy Council Energy—Institute of Nuclear Energy Research Radioimmunoassay with a 96-welled micro-plate
US9568431B2 (en) 2012-04-16 2017-02-14 Access Medical Systems, Ltd. Luminescent immunoassays for quantitating analytes having a wide concentration range

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2424465A1 (de) * 1974-05-20 1975-11-27 Biotest Serum Institut Gmbh Ve0hren zum gleichzeitigen nachweis von antigenen und deren antikoerpern im festkoerper-radioimmuntest
FR2277564A1 (fr) * 1974-07-10 1976-02-06 Abbott Lab Procede de dosage immunologique utilisant un systeme heterologue d'anticorps ou d'antigenes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE341239B (fr) * 1967-09-06 1971-12-20 Pharmacia Ab
US3826619A (en) * 1971-12-21 1974-07-30 Abbott Lab Test apparatus for direct radioimmuno-assay for antigens and their antibodies
US3949064A (en) * 1973-10-26 1976-04-06 Baxter Laboratories, Inc. Method of detecting antigens or antibodies
US3932141A (en) * 1974-07-10 1976-01-13 Abbott Laboratories Apparatus for determining immunoassays of antigens and their antibodies
US3951605A (en) * 1974-08-08 1976-04-20 Rohe Scientific Corporation Instrument for automated immunochemical analysis
US4155711A (en) * 1975-06-24 1979-05-22 Smutko Raymond A Method and apparatus for determining thyroid function of multiple samples
DE2625896C3 (de) * 1976-06-04 1979-09-06 Auergesellschaft Gmbh, 1000 Berlin Atemgerät
US4090850A (en) * 1976-11-01 1978-05-23 E. R. Squibb & Sons, Inc. Apparatus for use in radioimmunoassays
US4160803A (en) * 1978-03-23 1979-07-10 Corning Glass Works Self packaged test kit

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2424465A1 (de) * 1974-05-20 1975-11-27 Biotest Serum Institut Gmbh Ve0hren zum gleichzeitigen nachweis von antigenen und deren antikoerpern im festkoerper-radioimmuntest
FR2277564A1 (fr) * 1974-07-10 1976-02-06 Abbott Lab Procede de dosage immunologique utilisant un systeme heterologue d'anticorps ou d'antigenes

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2367286A1 (fr) * 1976-10-07 1978-05-05 Mochida Pharm Co Ltd Nouveau procede et reactifs de dosage immunochimique de substances physiologiquement actives
FR2377629A1 (fr) * 1977-01-14 1978-08-11 Suovaniemi Finnpipette Piece moulee pour appareils utilises pour les dosages immunologiques et les reactions enzymatiques
FR2383446A1 (fr) * 1977-03-11 1978-10-06 Abbott Lab Reactifs et procedes pour la mise en evidence de l'anticorps antinoyaux de dane
FR2459482A1 (fr) * 1979-06-14 1981-01-09 Abbott Lab Procedes et reactifs pour la detection simultanee de differents marqueurs de l'hepatite
EP0087899A2 (fr) * 1982-03-03 1983-09-07 Becton Dickinson and Company Dispositif d'examen à récipients multiples pour essais immunologiques
EP0087899A3 (en) * 1982-03-03 1983-11-02 Becton, Dickinson And Company Multi-well screening assembly for immunoassay procedures
EP0154686A2 (fr) * 1982-03-03 1985-09-18 Becton Dickinson and Company Plaque de support et dispositif d'examen à récipients multiples pour les essais immunologiques
EP0154687A2 (fr) * 1982-03-03 1985-09-18 Becton Dickinson and Company Plaque de support et dispositif d'examen pour les essais immunologiques
EP0154687A3 (en) * 1982-03-03 1988-12-07 Becton, Dickinson And Company Carrier plate and screening assembly for immunoassay procedures
EP0154686A3 (en) * 1982-03-03 1988-12-07 Becton, Dickinson And Company Carrier plate and multi-well screening assembly for immunoassay procedures

Also Published As

Publication number Publication date
SE7707310L (sv) 1978-02-21
DK305177A (da) 1978-02-21
ES461731A1 (es) 1978-05-16
DE2734118C3 (de) 1981-01-15
FR2362397B1 (fr) 1980-02-22
GB1562957A (en) 1980-03-19
AT343822B (de) 1978-06-26
US4276259A (en) 1981-06-30
FI65861C (fi) 1984-07-10
DE2734118A1 (de) 1978-03-02
BE857668A (fr) 1977-12-01
NL7708871A (nl) 1978-02-22
LU77986A1 (fr) 1978-01-11
CA1098441A (fr) 1981-03-31
FI772099A (fi) 1978-02-21
NO152670B (no) 1985-07-22
DK151398B (da) 1987-11-30
DE2734118B2 (de) 1980-04-24
FI65861B (fi) 1984-03-30
IT1086008B (it) 1985-05-28
NO772888L (no) 1978-02-21
ATA618576A (de) 1977-10-15
CH636258A5 (de) 1983-05-31
DK151398C (da) 1988-05-16
SE441868B (sv) 1985-11-11
NO152670C (no) 1985-10-30

Similar Documents

Publication Publication Date Title
FR2362397A1 (fr) Procede radio-immunologique et dispositif servant a determiner les antigenes
FR2325920A1 (fr) Dispositif pour l'echantillonnage, le melange de l'echantillon avec un reactif, et la mise en oeuvre d'une analyse notamment optique
FR2710410B1 (fr) Procédé et dispositif pour la détermination d'un analyte dans un échantillon .
SE8302377D0 (sv) Kerl for immunologisk analys
ATE16642T1 (de) Untersuchungsverfahren und -vorrichtung.
JPS5530692A (en) Method of immunological measuring
IT8019675A0 (it) Procedimento per rivelare ligandi in campioni di prova e relativo reagente analitico.
NO175657C (no) Fremgangsmåte for utförelse av en immunologisk bestemmelse av et antigen i en væskepröve samt reagens for bruk til dette
GB1358827A (en) Process for detecting the presence of human carcinoembryonic antigen material in blood
FR2371687A1 (fr) Procede et necessaire pour essai de dosage avec fixation specifique en utilisant de l'alcool polyvinylique comme agent de separation
FR2377416A1 (fr) Nouveaux antigenes lies au carcinome du sein
SE7706338L (sv) Sett och anordning for analysering
Fuchs et al. Neopterin estimation compared with the ratio of T-cell subpopulations in persons infected with human immunodeficiency virus-1.
FR2380553A1 (fr) Procede de detection de substances antigeniques et materiau pour la detection
FI841023A0 (fi) Foerfarande foer utfoering av immunobestaemningar
MY102881A (en) Method of automatically detecting agglutination reaction and apparatus therefor
JPS5748658A (en) Immunologic measuring method and reagent for measurement
ES462365A1 (es) Procedimiento y dispositivo para la deteccion de una protei-na fijadora especifica y la correspondiente sustancia sus- ceptible de fijarse con ella.
DK163022C (da) Fremgangsmaade til bestemmelse af en immunologisk bindedygtig analyt ved sandwichanalyse og maaling af tilbagedissociationshastighed
Van den Eeckhout et al. Radioimmunoassay of bromperidol and haloperidol in human and canine plasma
Hertl et al. Kinetic and thermodynamic studies of antigen-antibody interactions in heterogeneous reaction phases—I.: l-Thyroxine (T4) with specific antibody immobilized on controlled pore glass
IL100527A (en) Prescreening of prostate cancer by serum prostatic specific antigen
Mason et al. Direct radioimmunoassay for the detection of barbiturates in blood and urine
US5164090A (en) Process for the direct chromatographic analysis of drugs and metabolites in whole blood samples using internal surface reverse phase technology
Carpenter et al. Nitrogen determination in biological materials by the nuclear track technique

Legal Events

Date Code Title Description
ST Notification of lapse