FR2361418A1 - Procede d'obtention de derives n-glucosyliques des macrolides polyeniques ainsi que leurs sels, notamment des sels n-methylglucaminiques - Google Patents
Procede d'obtention de derives n-glucosyliques des macrolides polyeniques ainsi que leurs sels, notamment des sels n-methylglucaminiquesInfo
- Publication number
- FR2361418A1 FR2361418A1 FR7711907A FR7711907A FR2361418A1 FR 2361418 A1 FR2361418 A1 FR 2361418A1 FR 7711907 A FR7711907 A FR 7711907A FR 7711907 A FR7711907 A FR 7711907A FR 2361418 A1 FR2361418 A1 FR 2361418A1
- Authority
- FR
- France
- Prior art keywords
- salts
- methylglucaminic
- well
- salt
- obtaining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003839 salts Chemical class 0.000 title abstract 5
- 239000003120 macrolide antibiotic agent Substances 0.000 title abstract 3
- 150000004291 polyenes Chemical class 0.000 title abstract 3
- 229940041033 macrolides Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 abstract 3
- 208000007976 Ketosis Diseases 0.000 abstract 1
- 150000001323 aldoses Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 abstract 1
- 235000011130 ammonium sulphate Nutrition 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 229910017053 inorganic salt Inorganic materials 0.000 abstract 1
- 150000002584 ketoses Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920001542 oligosaccharide Polymers 0.000 abstract 1
- 150000002482 oligosaccharides Chemical class 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL1976188979A PL100966B1 (pl) | 1976-04-22 | 1976-04-22 | Sposob otrzymywania n-glikozylowych pochodnych makrolidow polienowych oraz ich soli,zwlaszcza soli n-metyloglukaminowej |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2361418A1 true FR2361418A1 (fr) | 1978-03-10 |
| FR2361418B1 FR2361418B1 (cs) | 1980-04-18 |
Family
ID=19976536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7711907A Granted FR2361418A1 (fr) | 1976-04-22 | 1977-04-20 | Procede d'obtention de derives n-glucosyliques des macrolides polyeniques ainsi que leurs sels, notamment des sels n-methylglucaminiques |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS52131594A (cs) |
| AU (1) | AU513015B2 (cs) |
| BE (1) | BE853893A (cs) |
| BR (1) | BR7702505A (cs) |
| CA (1) | CA1072088A (cs) |
| CH (1) | CH631995A5 (cs) |
| CS (1) | CS193092B2 (cs) |
| DD (1) | DD129331A5 (cs) |
| DE (1) | DE2717811C2 (cs) |
| DK (1) | DK178077A (cs) |
| ES (1) | ES458093A1 (cs) |
| FR (1) | FR2361418A1 (cs) |
| GB (1) | GB1582378A (cs) |
| HU (1) | HU177885B (cs) |
| IN (1) | IN144113B (cs) |
| IT (1) | IT1080375B (cs) |
| NL (1) | NL7704395A (cs) |
| PL (1) | PL100966B1 (cs) |
| RO (1) | RO71938A (cs) |
| SE (1) | SE7704604L (cs) |
| YU (1) | YU96677A (cs) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL122086B1 (en) * | 1979-04-09 | 1982-06-30 | Politechnika Gdanska | Process for preparing amides of antibiotics from the group of polyene macrolides and their derivativesvykh makrolidov i ikh proizvodnykh |
| GB2122892B (en) * | 1982-07-02 | 1986-01-29 | Squibb & Sons Inc | Nystantin pastille formulation |
| US9447136B2 (en) | 2012-03-09 | 2016-09-20 | Blirt S.A. | Semisynthetic derivatives of Nystatin A1 |
| JP2015519389A (ja) * | 2012-06-15 | 2015-07-09 | ブリート スポルカ アクシヤ | 抗真菌性抗生物質アンフォテリシンｂのｎ−置換第二世代誘導体ならびにそれらの調製および塗布方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI60877C (fi) * | 1971-08-13 | 1982-04-13 | Politechnika Gdanska | Foerfarande foer framstaellning av terapeutiskt aktiva i vatten laett dispergerbara polyenmakrolidantibiot-n-glykosylderivat |
| DE2417993C2 (de) * | 1974-04-11 | 1982-07-01 | Leningradskij naučno-issledovatel'skij institut antibiotikov, Leningrad | Polyenmacrolidantibiotica-Komplexe, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
-
1976
- 1976-04-22 PL PL1976188979A patent/PL100966B1/pl unknown
-
1977
- 1977-04-06 CH CH433677A patent/CH631995A5/de not_active IP Right Cessation
- 1977-04-12 YU YU00966/77A patent/YU96677A/xx unknown
- 1977-04-12 IN IN557/CAL/1977A patent/IN144113B/en unknown
- 1977-04-12 GB GB15058/77A patent/GB1582378A/en not_active Expired
- 1977-04-19 AU AU24418/77A patent/AU513015B2/en not_active Expired
- 1977-04-20 RO RO7790105A patent/RO71938A/ro unknown
- 1977-04-20 FR FR7711907A patent/FR2361418A1/fr active Granted
- 1977-04-20 DD DD7700198505A patent/DD129331A5/xx unknown
- 1977-04-21 DE DE2717811A patent/DE2717811C2/de not_active Expired
- 1977-04-21 IT IT22707/77A patent/IT1080375B/it active
- 1977-04-21 CA CA276,646A patent/CA1072088A/en not_active Expired
- 1977-04-21 SE SE7704604A patent/SE7704604L/xx not_active Application Discontinuation
- 1977-04-21 CS CS772666A patent/CS193092B2/cs unknown
- 1977-04-22 HU HU77PO646A patent/HU177885B/hu unknown
- 1977-04-22 JP JP4671377A patent/JPS52131594A/ja active Granted
- 1977-04-22 BE BE176963A patent/BE853893A/xx unknown
- 1977-04-22 NL NL7704395A patent/NL7704395A/xx not_active Application Discontinuation
- 1977-04-22 ES ES458093A patent/ES458093A1/es not_active Expired
- 1977-04-22 DK DK178077A patent/DK178077A/da unknown
- 1977-05-27 BR BR7702505A patent/BR7702505A/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE853893A (fr) | 1977-08-16 |
| JPS5721278B2 (cs) | 1982-05-06 |
| BR7702505A (pt) | 1978-03-21 |
| ES458093A1 (es) | 1978-03-16 |
| PL100966B1 (pl) | 1978-11-30 |
| DK178077A (da) | 1977-10-23 |
| DE2717811A1 (de) | 1977-10-27 |
| CH631995A5 (en) | 1982-09-15 |
| CS193092B2 (en) | 1979-09-17 |
| NL7704395A (nl) | 1977-10-25 |
| CA1072088A (en) | 1980-02-19 |
| YU96677A (en) | 1982-06-30 |
| IT1080375B (it) | 1985-05-16 |
| AU2441877A (en) | 1978-10-26 |
| SE7704604L (sv) | 1977-10-23 |
| GB1582378A (en) | 1981-01-07 |
| DD129331A5 (de) | 1978-01-11 |
| HU177885B (en) | 1982-01-28 |
| RO71938A (ro) | 1981-11-04 |
| DE2717811C2 (de) | 1983-10-20 |
| FR2361418B1 (cs) | 1980-04-18 |
| IN144113B (cs) | 1978-03-25 |
| JPS52131594A (en) | 1977-11-04 |
| AU513015B2 (en) | 1980-11-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |