FR2353854A1 - Methode et reactif d'analyse par liaison specifique - Google Patents

Methode et reactif d'analyse par liaison specifique

Info

Publication number
FR2353854A1
FR2353854A1 FR7716612A FR7716612A FR2353854A1 FR 2353854 A1 FR2353854 A1 FR 2353854A1 FR 7716612 A FR7716612 A FR 7716612A FR 7716612 A FR7716612 A FR 7716612A FR 2353854 A1 FR2353854 A1 FR 2353854A1
Authority
FR
France
Prior art keywords
reagent
analysis method
specific link
link analysis
specific
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7716612A
Other languages
English (en)
Other versions
FR2353854B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technion Research and Development Foundation Ltd
Original Assignee
Technion Research and Development Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technion Research and Development Foundation Ltd filed Critical Technion Research and Development Foundation Ltd
Publication of FR2353854A1 publication Critical patent/FR2353854A1/fr
Application granted granted Critical
Publication of FR2353854B1 publication Critical patent/FR2353854B1/fr
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C07D239/62—Barbituric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F11/00—Compounds containing elements of Groups 6 or 16 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00—Metallocenes
    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic System
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0011—Unsubstituted amino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/801—Electron dense compounds, e.g. ferritin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/816—Alkaloids, amphetamines, and barbiturates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
FR7716612A 1976-05-31 1977-05-31 Methode et reactif d'analyse par liaison specifique Granted FR2353854A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL49685A IL49685A (en) 1976-05-31 1976-05-31 Specific binding assay method for determining the concentration of materials and reagent means therefor

Publications (2)

Publication Number Publication Date
FR2353854A1 true FR2353854A1 (fr) 1977-12-30
FR2353854B1 FR2353854B1 (fr) 1983-08-26

Family

ID=11048893

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7716612A Granted FR2353854A1 (fr) 1976-05-31 1977-05-31 Methode et reactif d'analyse par liaison specifique

Country Status (9)

Country Link
US (1) US4205952A (fr)
JP (1) JPS52148620A (fr)
AU (1) AU517300B2 (fr)
CA (1) CA1100036A (fr)
DE (1) DE2724486C2 (fr)
FR (1) FR2353854A1 (fr)
GB (1) GB1550540A (fr)
IL (1) IL49685A (fr)
IT (1) IT1079695B (fr)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2408142A1 (fr) * 1977-11-03 1979-06-01 Du Pont Procede de determination immunochimique utilisant des reactifs marques
EP0007654A1 (fr) * 1978-07-13 1980-02-06 Akzo N.V. Procédé pour la détection et/ou l'identification, dans un échantillon-témoin aqueux, des constituants de la réaction entre une protéine spécifique de liaison et la substance correspondante pouvant étre liée; réactif séché par congélation et trousse à utiliser dans ce procédé
EP0064484A2 (fr) * 1981-04-30 1982-11-10 Wallac Oy Méthode pour la détermination par spectroscopie à fluorescence d'une substance à activité biologique
FR2533570A1 (fr) * 1982-09-23 1984-03-30 Centre Nat Rech Scient Complexes organometalliques d'oestrogenes et leur application au dosage des recepteurs hormonaux
EP0158746A2 (fr) * 1983-11-25 1985-10-23 Janssen Pharmaceutica N.V. Méthode de visualisation pour la détection directe ou indirecte de la réaction entre un agent de liaison spécifique et la substance acceptrice correspondante dans des essais "blot overlay"
FR2592047A1 (fr) * 1985-12-19 1987-06-26 Roussel Uclaf Complexes organometalliques de produits steroides ayant une affinite pour les recepteurs progestogene et gluco-corticoide et leur application au dosage des recepteurs hormonaux
WO1987004523A1 (fr) * 1986-01-23 1987-07-30 Robert Stephen Davidson Analyse de liaison et reactif d'analyse
WO1988007684A2 (fr) * 1987-04-03 1988-10-06 Centre National De La Recherche Scientifique (Cnrs Dosage immunologique infrarouge
FR2630547A1 (fr) * 1988-04-22 1989-10-27 Centre Nat Rech Scient Marquage froid de molecules de nature peptidique ou proteique
US5811526A (en) * 1986-01-23 1998-09-22 Alusuisse Holdings A.G. Binding assay and assay reagent

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DE2842862A1 (de) * 1978-10-02 1980-04-10 Boehringer Mannheim Gmbh Verfahren zur bestimmung von ionen, polaren und/oder lipophilen substanzen in fluessigkeiten
JPS55116259A (en) * 1979-03-01 1980-09-06 Fuji Photo Film Co Ltd Microimmunoassay method
JPS55116258A (en) * 1979-03-01 1980-09-06 Fuji Photo Film Co Ltd Microimmunoassay method
US4438207A (en) 1979-09-26 1984-03-20 Hoffmann-La Roche Inc. Radioimmunoassay for cannabinoids
US4375972A (en) * 1979-10-17 1983-03-08 Allied Corporation Heterogeneous chemiluminescent immunoassays utilizing metallo porphyrin tag
US4353886A (en) * 1980-05-05 1982-10-12 Irt Corporation Method for detecting organic vapors
US4357142A (en) * 1980-07-18 1982-11-02 Akzona Incorporated Glass support coated with synthetic polymer for bioprocess
IL60645A (en) * 1980-07-21 1984-02-29 Cais Michael Method and device for mass transfer and separation through selective barriers
JPS5832167A (ja) * 1981-08-20 1983-02-25 Sekisui Chem Co Ltd 免疫化学的測定法
US4454233A (en) * 1981-10-21 1984-06-12 Wang Associates Method of tagged immunoassay
US4994373A (en) 1983-01-27 1991-02-19 Enzo Biochem, Inc. Method and structures employing chemically-labelled polynucleotide probes
US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
US4766062A (en) * 1984-05-07 1988-08-23 Allied Corporation Displacement polynucleotide assay method and polynucleotide complex reagent therefor
US4766064A (en) * 1984-05-07 1988-08-23 Allied Corporation Displacement polynucleotide assay employing polyether and diagnostic kit
US5075447A (en) * 1984-09-17 1991-12-24 Hoffmann-La Roche Inc. Ruthenium complexes useful as carriers for immunologically active materials
DK365785A (da) * 1984-09-17 1986-03-18 Hoffmann La Roche Metalcomplexer
US5238808A (en) * 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
US5310687A (en) * 1984-10-31 1994-05-10 Igen, Inc. Luminescent metal chelate labels and means for detection
US5221605A (en) * 1984-10-31 1993-06-22 Igen, Inc. Luminescent metal chelate labels and means for detection
GB8504521D0 (en) * 1985-02-21 1985-03-27 Genetics Int Inc Electrochemical assay
US4767699A (en) * 1985-05-02 1988-08-30 Allied Corporation Diagnostic reagent, kit and method employing polynucleotide displacement, separation, enzymatic cleavage and adenosine phosphate detection
US4752566A (en) * 1985-12-17 1988-06-21 Genetics Institute, Inc. Displacement polynucleotide method and reagent complex employing labeled probe polynucleotide
AU6834187A (en) * 1985-12-17 1987-07-15 Genetics Institute Inc. Displacement polynucleotide method and reagent complex
US4818680A (en) * 1985-12-18 1989-04-04 Mary Collins Method and kit involving displacement and rehybridization of labeled polynucleotide
US4752568A (en) * 1986-01-13 1988-06-21 Eastman Kodak Company Labeled hydantoin conjugate and its use in analytical element and immunoassays
US6316607B1 (en) 1986-04-30 2001-11-13 Igen International, Inc. Electrochemiluminescent assays
KR960016340B1 (ko) * 1986-04-30 1996-12-09 이겐 인코오포레이팃드 전기화학발광 분석법
US4727024A (en) * 1986-05-12 1988-02-23 Martin Koocher Binding assays involving formation and detection of light scattering crystals
US5071775A (en) * 1986-08-13 1991-12-10 Massachusetts Institute Of Technology Indirect labeling method for post-separation detection of chemical compounds
US5264373A (en) * 1987-02-17 1993-11-23 Abbott Laboratories Fluorescence polarization immunoassay for tetrahydrocannabinoids
US5144030A (en) * 1987-02-17 1992-09-01 Abbott Laboratories Fluorescene polarization immunoassay for tetrahydrocannabinoids
JPH021557A (ja) * 1987-08-05 1990-01-05 Teijin Ltd 生体成分検出方法
US4859612A (en) * 1987-10-07 1989-08-22 Hygeia Sciences, Inc. Metal sol capture immunoassay procedure, kit for use therewith and captured metal containing composite
ATE259064T1 (de) 1987-11-04 2004-02-15 Igen Int Inc Lumineszente rhenium-komplexe und verfahren zur herstellung
US20050019760A1 (en) * 1988-03-05 2005-01-27 Oxford Gene Technology Limited Analysing polynucleotide sequences
GB8810400D0 (en) * 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
US5202267A (en) * 1988-04-04 1993-04-13 Hygeia Sciences, Inc. Sol capture immunoassay kit and procedure
US4921788A (en) * 1988-04-12 1990-05-01 The Research Foundation Of State University Of New York Competitive nucleic acid immunoassay for the detection of analytes
US7811751B2 (en) * 1988-05-03 2010-10-12 Oxford Gene Technology Limited Analysing polynucleotide sequences
AU2684488A (en) * 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
US5045479A (en) * 1988-07-05 1991-09-03 The Johns Hopkins University Continuous flow competitive assay with reference system
US5036014A (en) * 1989-01-31 1991-07-30 Elsohly Mahmoud A Deuterated cannabinoids as standards for the analysis of tetrahydrocannabinol and its metabolites in biological fluids
EP0386644B1 (fr) * 1989-03-10 1997-06-04 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Réactifs pour la détermination des drogues
US5252492A (en) * 1991-03-12 1993-10-12 University Of Utah Research Foundation Fluorescence assay for ligand or receptor utilizing size exclusion
US5998220A (en) * 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US5877028A (en) * 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
US5202006A (en) * 1992-04-17 1993-04-13 Beckman Instruments, Inc. Analysis of hemoglobin variants by capillary zone electrophoresis
US5891742A (en) * 1995-01-19 1999-04-06 Chiron Corporation Affinity selection of ligands by mass spectroscopy
WO1996033411A1 (fr) * 1995-04-18 1996-10-24 Igen, Inc. L'electrochimioluminescence de chelates de metaux de terres rares
US20010051350A1 (en) * 1995-05-02 2001-12-13 Albert Nazareth Diagnostic detection device and method
CA2228970A1 (fr) * 1995-08-18 1997-02-27 Donald W. Landry Detection de composes organiques par regulation de reactions catalysees par des anticorps
GB9606850D0 (en) * 1996-04-01 1996-06-05 Univ Liverpool An assay system and novel labelled compounds for use therwith
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US5824803A (en) * 1997-09-30 1998-10-20 The United States Of America As Represented By The Secretary Of The Navy Compounds labeled with cyanate or thiocyanate metal complexes for detection by infrared spectroscopy
DE10022750A1 (de) * 2000-05-10 2001-11-22 Wolfgang Schuhmann Verfahren zur Immobilisierung von Erkennungskomponenten
US20050244821A1 (en) * 2000-08-17 2005-11-03 Ory Zik Method of identification and quantification of biological molecules and apparatus therefore
US7700295B2 (en) * 2000-12-28 2010-04-20 Mds Sciex Elemental analysis of tagged biologically active materials
AU2002215784B2 (en) * 2000-12-28 2007-09-13 Dh Technologies Development Pte. Ltd. Elemental analysis of tagged biologically active materials
US7135296B2 (en) * 2000-12-28 2006-11-14 Mds Inc. Elemental analysis of tagged biologically active materials
US7479630B2 (en) 2004-03-25 2009-01-20 Bandura Dmitry R Method and apparatus for flow cytometry linked with elemental analysis
EP1534755B1 (fr) * 2002-05-10 2011-10-12 Bio-Layer Pty Limited Production de divers revetements de surface
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AU2005246289A1 (en) * 2004-05-15 2005-12-01 Genentech, Inc. Cross-screening system and methods for detecting a molecule having binding affinity for a target molecule
EP1773866B1 (fr) * 2004-07-02 2013-06-19 Bio-Layer Pty Limited Usage de complexes métalliques
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CN101384733A (zh) 2006-02-13 2009-03-11 奥尔加·奥尔纳茨基 通过元素分析实施的基因表达检测
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WO2008058004A2 (fr) 2006-11-02 2008-05-15 Winnik Mitchell A Particules contenant un code élémentaire détectable
WO2012097070A1 (fr) 2011-01-11 2012-07-19 The Board Of Trustees Of The Leland Stanford Junior University Points de masse : étiquettes isotopiques de nanoparticules
DE102012104504B4 (de) * 2012-05-24 2021-10-07 Bundesrepublik Deutschland, vertreten durch das Bundesministerium für Wirtschaft und Technologie, dieses vertreten durch den Präsidenten der BAM, Bundesanstalt für Materialforschung und -prüfung Polypeptidmarker
CN104059119A (zh) * 2014-06-10 2014-09-24 高海岗 雌二醇半抗原、抗原、抗体及其制备方法与应用
CN114705744A (zh) * 2022-04-02 2022-07-05 中国林业科学研究院高原林业研究所 一种测定没食子酸与金属离子结合常数方法

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Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2408142A1 (fr) * 1977-11-03 1979-06-01 Du Pont Procede de determination immunochimique utilisant des reactifs marques
EP0007654A1 (fr) * 1978-07-13 1980-02-06 Akzo N.V. Procédé pour la détection et/ou l'identification, dans un échantillon-témoin aqueux, des constituants de la réaction entre une protéine spécifique de liaison et la substance correspondante pouvant étre liée; réactif séché par congélation et trousse à utiliser dans ce procédé
EP0064484A2 (fr) * 1981-04-30 1982-11-10 Wallac Oy Méthode pour la détermination par spectroscopie à fluorescence d'une substance à activité biologique
EP0064484A3 (en) * 1981-04-30 1983-01-19 Wallac Oy Method for fluorescence spectroscopic determination of a biologically active substance
FR2533570A1 (fr) * 1982-09-23 1984-03-30 Centre Nat Rech Scient Complexes organometalliques d'oestrogenes et leur application au dosage des recepteurs hormonaux
EP0105785A1 (fr) * 1982-09-23 1984-04-18 Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) Complexes organométalliques d'oestrogènes et leur application au dosage des récepteurs hormonaux
EP0158746A3 (en) * 1983-11-25 1987-09-23 Janssen Pharmaceutica N.V. Visualization method for the direct or indirect detection of the reaction between a specific binding agent and the corresponding acceptor substance in blot overlay assays
EP0158746A2 (fr) * 1983-11-25 1985-10-23 Janssen Pharmaceutica N.V. Méthode de visualisation pour la détection directe ou indirecte de la réaction entre un agent de liaison spécifique et la substance acceptrice correspondante dans des essais "blot overlay"
FR2592047A1 (fr) * 1985-12-19 1987-06-26 Roussel Uclaf Complexes organometalliques de produits steroides ayant une affinite pour les recepteurs progestogene et gluco-corticoide et leur application au dosage des recepteurs hormonaux
WO1987004523A1 (fr) * 1986-01-23 1987-07-30 Robert Stephen Davidson Analyse de liaison et reactif d'analyse
US5811526A (en) * 1986-01-23 1998-09-22 Alusuisse Holdings A.G. Binding assay and assay reagent
WO1988007684A2 (fr) * 1987-04-03 1988-10-06 Centre National De La Recherche Scientifique (Cnrs Dosage immunologique infrarouge
FR2613490A1 (fr) * 1987-04-03 1988-10-07 Centre Nat Rech Scient Dosage immunologique infrarouge
WO1988007684A3 (fr) * 1987-04-03 1988-12-15 Centre Nat Rech Scient Dosage immunologique infrarouge
FR2630547A1 (fr) * 1988-04-22 1989-10-27 Centre Nat Rech Scient Marquage froid de molecules de nature peptidique ou proteique
WO1989010372A1 (fr) * 1988-04-22 1989-11-02 Centre National De La Recherche Scientifique (Cnrs Marquage froid de molecules de nature peptidique ou proteique

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AU2543777A (en) 1978-11-30
JPS52148620A (en) 1977-12-10
GB1550540A (en) 1979-08-15
DE2724486C2 (de) 1986-09-18
CA1100036A (fr) 1981-04-28
IL49685A0 (en) 1978-03-10
IL49685A (en) 1978-10-31
IT1079695B (it) 1985-05-13
JPS6128100B2 (fr) 1986-06-28
DE2724486A1 (de) 1977-12-22
US4205952A (en) 1980-06-03
FR2353854B1 (fr) 1983-08-26
AU517300B2 (en) 1981-07-23

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