WO1988007684A3 - Dosage immunologique infrarouge - Google Patents

Dosage immunologique infrarouge Download PDF

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Publication number
WO1988007684A3
WO1988007684A3 PCT/FR1988/000161 FR8800161W WO8807684A3 WO 1988007684 A3 WO1988007684 A3 WO 1988007684A3 FR 8800161 W FR8800161 W FR 8800161W WO 8807684 A3 WO8807684 A3 WO 8807684A3
Authority
WO
WIPO (PCT)
Prior art keywords
dosing
infrared
fourier transform
spectroscopic device
tag
Prior art date
Application number
PCT/FR1988/000161
Other languages
English (en)
Other versions
WO1988007684A2 (fr
Inventor
Gerard Jaquen
Ashraf A Ismail
Pierre Brossier
Original Assignee
Centre Nat Rech Scient
Gerard Jaquen
Ashraf A Ismail
Pierre Brossier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Gerard Jaquen, Ashraf A Ismail, Pierre Brossier filed Critical Centre Nat Rech Scient
Publication of WO1988007684A2 publication Critical patent/WO1988007684A2/fr
Publication of WO1988007684A3 publication Critical patent/WO1988007684A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N2021/3595—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using FTIR

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

L'invention concerne un nouveau type de dosage immunologique dénommé ''IRIA''. Selon la présente invention, on utilise un marqueur portant des fonctions carbonyles liées à au moins un métal. L'invention concerne également une détection du marqueur qui est réalisée par un dispositif de spectroscopie infrarouge à transformée de Fourier. L'invention concerne également un dispositif de spectroscopie IR à transformée de Fourier qui comporte séparément ou combinés entre eux les éléments suivants: un détecteur InSb; une fenêtre spectrale réduite; une cellule à long parcours de lumière et faible diamètre; un échantillon à doser liquide avec, de préférence, un solvant qui n'absorbe pas ou peu dans la région 2200-1800 cm-1.
PCT/FR1988/000161 1987-04-03 1988-03-31 Dosage immunologique infrarouge WO1988007684A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8704698A FR2613490A1 (fr) 1987-04-03 1987-04-03 Dosage immunologique infrarouge
FR87/04698 1987-04-03

Publications (2)

Publication Number Publication Date
WO1988007684A2 WO1988007684A2 (fr) 1988-10-06
WO1988007684A3 true WO1988007684A3 (fr) 1988-12-15

Family

ID=9349757

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1988/000161 WO1988007684A2 (fr) 1987-04-03 1988-03-31 Dosage immunologique infrarouge

Country Status (3)

Country Link
EP (1) EP0308473A1 (fr)
FR (1) FR2613490A1 (fr)
WO (1) WO1988007684A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2630547A1 (fr) * 1988-04-22 1989-10-27 Centre Nat Rech Scient Marquage froid de molecules de nature peptidique ou proteique
GB9110017D0 (en) * 1991-05-09 1991-07-03 Nat Res Dev Spectroscopic investigation using organometallic compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2353854A1 (fr) * 1976-05-31 1977-12-30 Technion Res & Dev Foundation Methode et reactif d'analyse par liaison specifique

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2353854A1 (fr) * 1976-05-31 1977-12-30 Technion Res & Dev Foundation Methode et reactif d'analyse par liaison specifique

Also Published As

Publication number Publication date
EP0308473A1 (fr) 1989-03-29
FR2613490A1 (fr) 1988-10-07
WO1988007684A2 (fr) 1988-10-06

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