FR2353534A1 - Derives nouveaux de 4-hydroxy-aporphine, leur mode preparation et leur application pharmacologique - Google Patents

Derives nouveaux de 4-hydroxy-aporphine, leur mode preparation et leur application pharmacologique

Info

Publication number
FR2353534A1
FR2353534A1 FR7716976A FR7716976A FR2353534A1 FR 2353534 A1 FR2353534 A1 FR 2353534A1 FR 7716976 A FR7716976 A FR 7716976A FR 7716976 A FR7716976 A FR 7716976A FR 2353534 A1 FR2353534 A1 FR 2353534A1
Authority
FR
France
Prior art keywords
aporphine
hydroxy
preparation
new derivatives
pharmacological application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7716976A
Other languages
English (en)
French (fr)
Other versions
FR2353534B1 (enExample
Inventor
Johannes Hartenstein
Gerhard Satzinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of FR2353534A1 publication Critical patent/FR2353534A1/fr
Application granted granted Critical
Publication of FR2353534B1 publication Critical patent/FR2353534B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FR7716976A 1976-06-04 1977-06-03 Derives nouveaux de 4-hydroxy-aporphine, leur mode preparation et leur application pharmacologique Granted FR2353534A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2625116A DE2625116C2 (de) 1976-06-04 1976-06-04 Verfahren zur Herstellung von 4-Hydroxy-aporphin-Derivaten

Publications (2)

Publication Number Publication Date
FR2353534A1 true FR2353534A1 (fr) 1977-12-30
FR2353534B1 FR2353534B1 (enExample) 1980-03-07

Family

ID=5979808

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7716976A Granted FR2353534A1 (fr) 1976-06-04 1977-06-03 Derives nouveaux de 4-hydroxy-aporphine, leur mode preparation et leur application pharmacologique

Country Status (14)

Country Link
US (1) US4120964A (enExample)
JP (1) JPS535169A (enExample)
AU (1) AU508171B2 (enExample)
BE (1) BE855412A (enExample)
CH (1) CH629782A5 (enExample)
DE (1) DE2625116C2 (enExample)
DK (1) DK248277A (enExample)
ES (1) ES459504A1 (enExample)
FR (1) FR2353534A1 (enExample)
GB (1) GB1521020A (enExample)
IE (1) IE44937B1 (enExample)
LU (1) LU77482A1 (enExample)
NL (1) NL7706180A (enExample)
SE (1) SE433212B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2412534A1 (fr) * 1977-12-22 1979-07-20 Warner Lambert Co Preparation de derives de 1-hydroxyaporphines
FR2430942A1 (fr) * 1977-12-22 1980-02-08 Warner Lambert Co Preparation de derives o-methyliques d'hydroxyaporphines

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI68813C (fi) * 1978-08-21 1985-11-11 Dow Chemical Co Foerfarande foer framstaellning av terapeutiskt effektiva 1- och d,1-glausinfosfatsalter
DE3324089A1 (de) * 1983-07-05 1985-01-17 Basf Ag, 6700 Ludwigshafen Elektrophotographische aufzeichnungsmaterialien mit verbesserter photoempfindlichkeit
DE3324090A1 (de) * 1983-07-05 1985-01-17 Basf Ag, 6700 Ludwigshafen Elektrophotographische aufzeichnungsmaterialien mit verbesserter photoempfindlichkeit
US5156847A (en) * 1990-09-20 1992-10-20 Walter H. Lewis Wound-healing composition
US5474782A (en) * 1994-05-20 1995-12-12 Woundfast Pharmaceuticals, Inc. Wound-healing composition and method
US5659037A (en) * 1994-08-18 1997-08-19 Abbott Laboratories Process for preparing chiral tetracyclic dopaminergic compounds
DE19535762A1 (de) * 1995-09-26 1997-03-27 Basf Ag Verfahren zur Racematspaltung
US5932617A (en) * 1998-02-06 1999-08-03 Woundfast Pharmaceuticals Inc. Wound-treating composition and method
US6210680B1 (en) 1999-06-11 2001-04-03 Univera Pharmaceuticals, Inc. Method for the prevention and treatment of chronic venous insufficiency
US20030187011A1 (en) * 2001-12-20 2003-10-02 Lashuel Hilal A. Apomorphine inhibitors of amyloid-beta (Abeta) fibril formation and their use in amyloidosis based disease
TWI404536B (zh) * 2008-06-20 2013-08-11 Standard Chem & Pharm Co Ltd 阿朴芬化合物及其醫藥用途
CN105315208A (zh) * 2014-07-17 2016-02-10 中国科学院兰州化学物理研究所 阿朴菲类生物碱及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3131191A (en) * 1962-08-08 1964-04-28 Smith Kline French Lab Process for the preparation of noraporphines

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2412534A1 (fr) * 1977-12-22 1979-07-20 Warner Lambert Co Preparation de derives de 1-hydroxyaporphines
FR2430942A1 (fr) * 1977-12-22 1980-02-08 Warner Lambert Co Preparation de derives o-methyliques d'hydroxyaporphines

Also Published As

Publication number Publication date
DK248277A (da) 1977-12-05
IE44937L (en) 1977-12-04
JPS535169A (en) 1978-01-18
FR2353534B1 (enExample) 1980-03-07
BE855412A (fr) 1977-12-05
CH629782A5 (de) 1982-05-14
AU508171B2 (en) 1980-03-13
IE44937B1 (en) 1982-05-19
LU77482A1 (enExample) 1977-09-22
SE433212B (sv) 1984-05-14
ES459504A1 (es) 1978-05-01
DE2625116C2 (de) 1984-01-26
GB1521020A (en) 1978-08-09
AU2580977A (en) 1978-12-07
DE2625116A1 (de) 1977-12-22
US4120964A (en) 1978-10-17
SE7706488L (sv) 1977-12-05
NL7706180A (nl) 1977-12-06

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Legal Events

Date Code Title Description
ST Notification of lapse