BE827844A - Nouveaux derives de la pyridine, leur preparation et leur utilisations - Google Patents
Nouveaux derives de la pyridine, leur preparation et leur utilisationsInfo
- Publication number
- BE827844A BE827844A BE155330A BE155330A BE827844A BE 827844 A BE827844 A BE 827844A BE 155330 A BE155330 A BE 155330A BE 155330 A BE155330 A BE 155330A BE 827844 A BE827844 A BE 827844A
- Authority
- BE
- Belgium
- Prior art keywords
- pyridine
- preparation
- new derivatives
- derivatives
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- C07D213/71—Sulfur atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1683674A GB1477664A (en) | 1974-04-17 | 1974-04-17 | Pyridine derivatives |
YU1507/81A YU42409B (en) | 1974-04-17 | 1981-06-15 | Process for obtaining new pyridine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BE827844A true BE827844A (fr) | 1975-10-13 |
Family
ID=26252269
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE155330A BE827844A (fr) | 1974-04-17 | 1975-04-11 | Nouveaux derives de la pyridine, leur preparation et leur utilisations |
Country Status (19)
Country | Link |
---|---|
US (2) | US4018929A (fr) |
JP (1) | JPS5951536B2 (fr) |
AR (4) | AR211097A1 (fr) |
AT (1) | AT344170B (fr) |
BE (1) | BE827844A (fr) |
CA (1) | CA1070313A (fr) |
CH (3) | CH612424A5 (fr) |
DD (2) | DD126887A5 (fr) |
DE (1) | DE2516025A1 (fr) |
ES (4) | ES436581A1 (fr) |
FR (1) | FR2267775B1 (fr) |
GB (1) | GB1477664A (fr) |
HU (1) | HU171420B (fr) |
IL (1) | IL47084A (fr) |
LU (2) | LU72284A1 (fr) |
NL (2) | NL183580C (fr) |
SE (2) | SE424320B (fr) |
YU (1) | YU42409B (fr) |
ZA (1) | ZA752243B (fr) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1593609A (en) * | 1978-01-31 | 1981-07-22 | Christiaens Sa A | Pyridine sulfonamides |
US4776878A (en) * | 1978-12-04 | 1988-10-11 | E. I. Du Pont De Nemours And Company | Agricultural pyridinesulfonamides |
LU85193A1 (fr) * | 1984-01-31 | 1985-09-12 | Christiaens Sa A | Nouveaux derives de la 4-phenylaminopyridine,leur utilisation et leur preparation |
DE3529529A1 (de) * | 1985-08-17 | 1987-02-19 | Boehringer Mannheim Gmbh | Verfahren zur herstellung einer stabilen modifikation von torasemid |
US4914203A (en) * | 1987-07-24 | 1990-04-03 | American Home Products Corporation | 5 step process for preparing certain 2,4-diamino-5-pyrimidine-sulfonyl ureas |
US4853389A (en) * | 1987-07-24 | 1989-08-01 | American Home Products Corporation | Diuretic and antihypertensive substituted-5-pyrimidinesulfonylureas |
FR2659080B1 (fr) * | 1990-03-02 | 1994-07-08 | Adir | Nouveaux derives de la pyridylsulfonyluree et de la pyridylsulfonylthiouree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
US5166162A (en) * | 1990-03-02 | 1992-11-24 | Adir Et Compagnie | Pyridylsulfonylurea and pyridylsulfonylthiourea compounds |
US5486530A (en) * | 1991-04-27 | 1996-01-23 | Boehringer Mannheim Gmbh | Use of torasemide for the treatment of brain oedemas |
IT1288123B1 (it) * | 1996-09-04 | 1998-09-10 | Nicox Sa | Uso di nitroderivati per l'incontinenza urinaria |
HRP980532B1 (en) * | 1998-10-02 | 2005-06-30 | Pliva | Novel crystalline torasemide modification |
US6166045A (en) * | 1998-06-02 | 2000-12-26 | Roche Diagnostics Gmbh | Torasemide of modification III |
US7214711B2 (en) * | 1998-12-23 | 2007-05-08 | Neurotherapeutics Pharma Llc | Method of treating migraine headache without aura |
US8722668B2 (en) * | 1998-12-23 | 2014-05-13 | Daryl W. Hochman | Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders |
US8008283B2 (en) * | 1998-12-23 | 2011-08-30 | Neurotherapeutics Pharma, Inc. | Methods and compositions for the treatment of neuropsychiatric disorders |
CA2379322A1 (fr) * | 1999-08-11 | 2001-02-15 | Teva Pharmaceutical Industries Ltd. | Polymorphes de torsemide |
SK11632003A3 (sk) * | 2000-02-17 | 2004-04-06 | Teva Pharmaceutical Industries Ltd. | Stabilný farmaceutický prípravok obsahujúci modifikáciu II torsemidu |
HRP20000162B1 (en) | 2000-03-20 | 2004-06-30 | Pliva D D | Amorphous torasemide modification |
EP1741429A3 (fr) * | 2000-03-20 | 2007-01-17 | Teva Pharmaceutical Industries Ltd. | Procédé pour la préparation de torsemide |
CA2403382A1 (fr) * | 2000-03-20 | 2001-09-27 | Teva Pharmaceutical Industries Ltd. | Nouveaux procedes de preparation d'un intermediaire de torsemide |
HRP20000328A2 (en) | 2000-05-19 | 2002-02-28 | Pliva Farmaceutska Ind Dionik | Novel polymorph v of torasemide |
US20030022921A1 (en) * | 2001-02-21 | 2003-01-30 | Minutza Leibovici | Stable pharmaceutical formulation comprising torsemide modification II |
IN192178B (fr) | 2001-08-03 | 2004-03-06 | Ranbaxy Lab | |
IL149771A0 (en) * | 2002-05-21 | 2002-11-10 | Fintech Lab Ltd | Process for preparation of torsemide |
HRP20020603B1 (en) * | 2002-07-19 | 2008-11-30 | Pliva D.D. | New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide |
AP2005003232A0 (en) | 2002-08-19 | 2005-03-31 | Pfizer Prod Inc | Combination therapy for hyperproliferative diseases. |
CA2401546C (fr) * | 2002-09-06 | 2006-09-19 | Brantford Chemicals Inc. | Synthese de derives de la 3-sulfonamido-4-phenylaminopyridine |
ITMI20022749A1 (it) * | 2002-12-23 | 2004-06-24 | Cosma S P A | Nuovo procedimento per la sintesi della tosemide, in particolare della forma ii pura e stabile. |
US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
US20050215600A1 (en) * | 2003-10-27 | 2005-09-29 | Arie Gutman | Polymorphs of torsemide hydrochloride and process for production thereof |
US7378527B2 (en) * | 2004-03-16 | 2008-05-27 | Daqing Che | Process for the preparation of torsemide and related intermediates |
US20070149526A1 (en) * | 2005-10-17 | 2007-06-28 | Neurotherapeutics Pharma, L.L.C. | Diuretic and diuretic-like compound analogs |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
US7625896B2 (en) * | 2005-11-25 | 2009-12-01 | Hoffman-La Roche Inc. | Pyridylsulfonamide derivatives |
US7939532B2 (en) * | 2006-10-26 | 2011-05-10 | Hoffmann-La Roche Inc. | Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents |
US8404896B2 (en) | 2006-12-01 | 2013-03-26 | Bristol-Myers Squibb Company | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases |
CN101675033A (zh) * | 2007-05-16 | 2010-03-17 | 霍夫曼-拉罗奇有限公司 | 芳基吡啶基磺酰胺衍生物,它们的制备和作为药剂的应用 |
NL2006622C2 (en) | 2011-04-18 | 2012-10-22 | Eurovet Animal Health B V | Use of a composition comprising torasemide. |
WO2014014519A1 (fr) | 2012-07-20 | 2014-01-23 | University Of Rochester | Méthode de traitement et de prévention d'une atteinte cérébrale faisant appel à des inhibiteurs de l'isoforme 1 du cotransporteur na+-k+-2cl- |
BR112015026513A2 (pt) | 2013-04-17 | 2017-07-25 | Pfizer | derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares |
WO2016055901A1 (fr) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Composés d'amide substitué |
EP3578547B1 (fr) * | 2015-02-16 | 2021-05-26 | The University of Queensland | Sulfonylurées, composés apparentés, et leur utilisation |
WO2019008025A1 (fr) | 2017-07-07 | 2019-01-10 | Inflazome Limited | Nouveaux composés de sulfonamide carboxamide |
MX2021008533A (es) | 2019-01-18 | 2021-08-19 | Astrazeneca Ab | Inhibidores de la pcsk9 y metodos de uso de los mismos. |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3674794A (en) * | 1970-03-18 | 1972-07-04 | Ciba Geigy Corp | Certain-3-pyridine-sulfonamide derivatives |
GB1368948A (en) * | 1970-11-11 | 1974-10-02 | Manuf Prod Pharma | Pyridine derivatives |
GB1414793A (en) * | 1972-07-28 | 1975-11-19 | Manuf Prod Pharma | Derivatives of phenylaminopyridine |
US3904636A (en) * | 1971-11-09 | 1975-09-09 | Christiaens Sa A | 3-sulfonamido-4-phenyl aminopyridines and derivatives |
-
1974
- 1974-04-17 GB GB1683674A patent/GB1477664A/en not_active Expired
-
1975
- 1975-04-08 ZA ZA00752243A patent/ZA752243B/xx unknown
- 1975-04-11 BE BE155330A patent/BE827844A/fr not_active IP Right Cessation
- 1975-04-12 DE DE19752516025 patent/DE2516025A1/de active Granted
- 1975-04-14 HU HU75CI00001569A patent/HU171420B/hu unknown
- 1975-04-14 IL IL47084A patent/IL47084A/xx unknown
- 1975-04-14 ES ES436581A patent/ES436581A1/es not_active Expired
- 1975-04-15 LU LU72284A patent/LU72284A1/xx unknown
- 1975-04-16 CH CH216478A patent/CH612424A5/xx not_active IP Right Cessation
- 1975-04-16 CH CH216378A patent/CH610890A5/xx active Protection Beyond IP Right Term
- 1975-04-16 FR FR7511791A patent/FR2267775B1/fr not_active Expired
- 1975-04-16 CA CA224,805A patent/CA1070313A/fr not_active Expired
- 1975-04-16 SE SE7504409A patent/SE424320B/xx unknown
- 1975-04-16 AT AT288275A patent/AT344170B/de not_active IP Right Cessation
- 1975-04-16 US US05/568,759 patent/US4018929A/en not_active Expired - Lifetime
- 1975-04-16 NL NLAANVRAGE7504521,A patent/NL183580C/xx active Protection Beyond IP Right Term
- 1975-04-16 CH CH485775A patent/CH609045A5/xx active Protection Beyond IP Right Term
- 1975-04-17 AR AR258409A patent/AR211097A1/es active
- 1975-04-17 DD DD194800A patent/DD126887A5/xx unknown
- 1975-04-17 JP JP50047371A patent/JPS5951536B2/ja not_active Expired
- 1975-04-17 DD DD185508A patent/DD121936A5/xx unknown
-
1976
- 1976-03-19 AR AR262627A patent/AR208770A1/es active
- 1976-03-19 AR AR262625A patent/AR208768A1/es active
- 1976-03-19 AR AR262626A patent/AR208769A1/es active
- 1976-11-15 ES ES453327A patent/ES453327A1/es not_active Expired
- 1976-11-15 ES ES453328A patent/ES453328A1/es not_active Expired
- 1976-11-15 ES ES453329A patent/ES453329A1/es not_active Expired
-
1979
- 1979-09-13 SE SE7907618A patent/SE7907618L/sv not_active Application Discontinuation
-
1980
- 1980-02-07 US US06/119,601 patent/USRE30633E/en not_active Expired - Lifetime
-
1981
- 1981-06-15 YU YU1507/81A patent/YU42409B/xx unknown
-
1993
- 1993-06-30 LU LU88346C patent/LU88346I2/fr unknown
-
1994
- 1994-07-27 NL NL940014C patent/NL940014I2/nl unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CCPA | Application for a supplementary protection certificate |
Free format text: 093C0138 |
|
CCPV | Grant of a supplementary protection certificate |
Free format text: 093C0138, EXPIRES 20000411 |
|
RE20 | Patent expired |
Owner name: S.A. NYCOMED CHRISTIAENS Effective date: 19950411 |