BE827844A - Nouveaux derives de la pyridine, leur preparation et leur utilisations - Google Patents

Nouveaux derives de la pyridine, leur preparation et leur utilisations

Info

Publication number
BE827844A
BE827844A BE155330A BE155330A BE827844A BE 827844 A BE827844 A BE 827844A BE 155330 A BE155330 A BE 155330A BE 155330 A BE155330 A BE 155330A BE 827844 A BE827844 A BE 827844A
Authority
BE
Belgium
Prior art keywords
pyridine
preparation
new derivatives
derivatives
new
Prior art date
Application number
BE155330A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE827844A publication Critical patent/BE827844A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C07D213/71—Sulfur atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
BE155330A 1974-04-17 1975-04-11 Nouveaux derives de la pyridine, leur preparation et leur utilisations BE827844A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1683674A GB1477664A (en) 1974-04-17 1974-04-17 Pyridine derivatives
YU1507/81A YU42409B (en) 1974-04-17 1981-06-15 Process for obtaining new pyridine derivatives

Publications (1)

Publication Number Publication Date
BE827844A true BE827844A (fr) 1975-10-13

Family

ID=26252269

Family Applications (1)

Application Number Title Priority Date Filing Date
BE155330A BE827844A (fr) 1974-04-17 1975-04-11 Nouveaux derives de la pyridine, leur preparation et leur utilisations

Country Status (19)

Country Link
US (2) US4018929A (fr)
JP (1) JPS5951536B2 (fr)
AR (4) AR211097A1 (fr)
AT (1) AT344170B (fr)
BE (1) BE827844A (fr)
CA (1) CA1070313A (fr)
CH (3) CH610890A5 (fr)
DD (2) DD126887A5 (fr)
DE (1) DE2516025A1 (fr)
ES (4) ES436581A1 (fr)
FR (1) FR2267775B1 (fr)
GB (1) GB1477664A (fr)
HU (1) HU171420B (fr)
IL (1) IL47084A (fr)
LU (2) LU72284A1 (fr)
NL (2) NL183580C (fr)
SE (2) SE424320B (fr)
YU (1) YU42409B (fr)
ZA (1) ZA752243B (fr)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593609A (en) * 1978-01-31 1981-07-22 Christiaens Sa A Pyridine sulfonamides
US4776878A (en) * 1978-12-04 1988-10-11 E. I. Du Pont De Nemours And Company Agricultural pyridinesulfonamides
LU85193A1 (fr) * 1984-01-31 1985-09-12 Christiaens Sa A Nouveaux derives de la 4-phenylaminopyridine,leur utilisation et leur preparation
DE3529529A1 (de) * 1985-08-17 1987-02-19 Boehringer Mannheim Gmbh Verfahren zur herstellung einer stabilen modifikation von torasemid
US4853389A (en) * 1987-07-24 1989-08-01 American Home Products Corporation Diuretic and antihypertensive substituted-5-pyrimidinesulfonylureas
US4914203A (en) * 1987-07-24 1990-04-03 American Home Products Corporation 5 step process for preparing certain 2,4-diamino-5-pyrimidine-sulfonyl ureas
FR2659080B1 (fr) * 1990-03-02 1994-07-08 Adir Nouveaux derives de la pyridylsulfonyluree et de la pyridylsulfonylthiouree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5166162A (en) * 1990-03-02 1992-11-24 Adir Et Compagnie Pyridylsulfonylurea and pyridylsulfonylthiourea compounds
US5486530A (en) * 1991-04-27 1996-01-23 Boehringer Mannheim Gmbh Use of torasemide for the treatment of brain oedemas
IT1288123B1 (it) * 1996-09-04 1998-09-10 Nicox Sa Uso di nitroderivati per l'incontinenza urinaria
HRP980532B1 (en) 1998-10-02 2005-06-30 Pliva Novel crystalline torasemide modification
US6166045A (en) * 1998-06-02 2000-12-26 Roche Diagnostics Gmbh Torasemide of modification III
US7214711B2 (en) * 1998-12-23 2007-05-08 Neurotherapeutics Pharma Llc Method of treating migraine headache without aura
US8008283B2 (en) * 1998-12-23 2011-08-30 Neurotherapeutics Pharma, Inc. Methods and compositions for the treatment of neuropsychiatric disorders
US8722668B2 (en) * 1998-12-23 2014-05-13 Daryl W. Hochman Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders
AU781461C (en) * 1999-08-11 2006-02-23 Teva Pharmaceutical Industries Ltd. Torsemide polymorphs
SI1292303T1 (en) 2000-02-17 2004-10-31 Teva Pharmaceutical Industries Ltd. A stable pharmaceutical formulation comprising torsemide modification ii
EP1741429A3 (fr) * 2000-03-20 2007-01-17 Teva Pharmaceutical Industries Ltd. Procédé pour la préparation de torsemide
HRP20000162B1 (en) * 2000-03-20 2004-06-30 Pliva D D Amorphous torasemide modification
AU2001247592B2 (en) * 2000-03-20 2005-08-18 Teva Pharmaceutical Industries Ltd. Novel processes for preparing torsemide intermediate
HRP20000328A2 (en) * 2000-05-19 2002-02-28 Pliva Farmaceutska Ind Dionik Novel polymorph v of torasemide
US20030022921A1 (en) * 2001-02-21 2003-01-30 Minutza Leibovici Stable pharmaceutical formulation comprising torsemide modification II
IN192178B (fr) 2001-08-03 2004-03-06 Ranbaxy Lab
IL149771A0 (en) * 2002-05-21 2002-11-10 Fintech Lab Ltd Process for preparation of torsemide
HRP20020603B1 (en) * 2002-07-19 2008-11-30 Pliva D.D. New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide
ES2362998T3 (es) 2002-08-19 2011-07-18 Pfizer Inc. Terapia de combinación para enfermedades hiperproliferativas.
CA2401546C (fr) * 2002-09-06 2006-09-19 Brantford Chemicals Inc. Synthese de derives de la 3-sulfonamido-4-phenylaminopyridine
ITMI20022749A1 (it) * 2002-12-23 2004-06-24 Cosma S P A Nuovo procedimento per la sintesi della tosemide, in particolare della forma ii pura e stabile.
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
US20050215600A1 (en) * 2003-10-27 2005-09-29 Arie Gutman Polymorphs of torsemide hydrochloride and process for production thereof
US7378527B2 (en) * 2004-03-16 2008-05-27 Daqing Che Process for the preparation of torsemide and related intermediates
WO2007047447A2 (fr) * 2005-10-17 2007-04-26 Neurotherapeutics Pharma, Inc. Analogues de compose diuretique ou de type diuretique
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7625896B2 (en) * 2005-11-25 2009-12-01 Hoffman-La Roche Inc. Pyridylsulfonamide derivatives
US7939532B2 (en) * 2006-10-26 2011-05-10 Hoffmann-La Roche Inc. Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents
CN101663262B (zh) 2006-12-01 2014-03-26 百时美施贵宝公司 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
EP2148861A1 (fr) * 2007-05-16 2010-02-03 F. Hoffmann-Roche AG Dérivés d'aryl pyridyl sulfonamide, leur fabrication et leur utilisation en tant qu'agents pharmaceutiques
NL2006622C2 (en) 2011-04-18 2012-10-22 Eurovet Animal Health B V Use of a composition comprising torasemide.
EP2887806B1 (fr) 2012-07-20 2019-11-13 University Of Rochester Méthode de traitement et de prévention d'une atteinte cérébrale faisant appel à des inhibiteurs de l'isoforme 1 du cotransporteur na+-k+ -2ci
EP2986599A1 (fr) 2013-04-17 2016-02-24 Pfizer Inc. Dérivés de n-pipéridin-3-ylbenzamide dans le traitement des maladies cardiovasculaires
WO2016055901A1 (fr) 2014-10-08 2016-04-14 Pfizer Inc. Composés d'amide substitué
MA41553B1 (fr) * 2015-02-16 2020-04-30 The Provost Fellows Found Scholars And The Other Members Of Board Of The College Of The Holy & Undiv Sulfonylurées, composés apparentés, et leur utilisation
DK3661925T3 (da) 2017-07-07 2022-02-28 Inflazome Ltd Hidtil ukendte sulfonamidcarboxamidforbindelser
CA3125765A1 (fr) 2019-01-18 2020-07-23 Astrazeneca Ab Inhibiteurs de pcsk9 et leurs procedes d'utilisation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3674794A (en) * 1970-03-18 1972-07-04 Ciba Geigy Corp Certain-3-pyridine-sulfonamide derivatives
GB1368948A (en) * 1970-11-11 1974-10-02 Manuf Prod Pharma Pyridine derivatives
US3904636A (en) * 1971-11-09 1975-09-09 Christiaens Sa A 3-sulfonamido-4-phenyl aminopyridines and derivatives
GB1414793A (en) * 1972-07-28 1975-11-19 Manuf Prod Pharma Derivatives of phenylaminopyridine

Also Published As

Publication number Publication date
NL940014I2 (nl) 1997-04-01
AR208769A1 (es) 1977-02-28
LU88346I2 (fr) 1994-05-04
CH609045A5 (fr) 1979-02-15
ES453327A1 (es) 1977-11-16
DE2516025A1 (de) 1975-11-06
ES436581A1 (es) 1977-04-01
DE2516025C2 (fr) 1988-11-03
CH612424A5 (fr) 1979-07-31
NL183580B (nl) 1988-07-01
SE7504409L (sv) 1975-10-20
IL47084A (en) 1979-01-31
IL47084A0 (en) 1975-06-25
JPS5951536B2 (ja) 1984-12-14
ES453329A1 (es) 1977-11-16
ZA752243B (en) 1976-03-31
LU72284A1 (fr) 1975-08-20
USRE30633E (en) 1981-06-02
HU171420B (hu) 1978-01-28
US4018929A (en) 1977-04-19
NL940014I1 (nl) 1994-09-16
CA1070313A (fr) 1980-01-22
NL183580C (nl) 1988-12-01
DD121936A5 (fr) 1976-09-05
YU42409B (en) 1988-08-31
ATA288275A (de) 1977-11-15
DD126887A5 (fr) 1977-08-17
FR2267775A1 (fr) 1975-11-14
YU150781A (en) 1984-02-29
FR2267775B1 (fr) 1978-11-10
ES453328A1 (es) 1977-11-01
AR208768A1 (es) 1977-02-28
SE424320B (sv) 1982-07-12
AU8001675A (en) 1976-10-14
GB1477664A (en) 1977-06-22
AT344170B (de) 1978-07-10
AR211097A1 (es) 1977-10-31
CH610890A5 (fr) 1979-05-15
AR208770A1 (es) 1977-02-28
SE7907618L (sv) 1979-09-13
NL7504521A (nl) 1975-10-21
JPS50142571A (fr) 1975-11-17

Similar Documents

Publication Publication Date Title
BE827844A (fr) Nouveaux derives de la pyridine, leur preparation et leur utilisations
FR2320295A1 (fr) Nouveaux derives de la 2,3-dioxopiperazine et leur procede de preparation
BE789629A (fr) Nouveaux derives de la pleuromutiline, leur preparation et leurapplication en therapeutique
BE873656A (fr) Nouveaux derives de la pyridine, leur preparation et leur utilisation
FR2345150A2 (fr) Nouveaux derives de la thienopyridine, et leur application
FR2353534A1 (fr) Derives nouveaux de 4-hydroxy-aporphine, leur mode preparation et leur application pharmacologique
BE834400A (fr) Nouveaux derives de pyridine, leur procede de preparation et leur utilisation
FR2342724A1 (fr) Derives de 16,16-spirocycloalkylprostaglandines, leur preparation et leurs utilisations therapeutiques
BE815498A (fr) Derives de triazolo-isoquinoleine et leur preparation
BE827326A (fr) Nouveaux derives de pyridine, leur preparation et leur utilisation
FR2318853A1 (fr) Derives de dodecatetraene, leur preparation et leurs utilisations
FR2290207A1 (fr) Nouveaux derives de 3,4-dihydrocarbostyril et leur procede de preparation
BE833291A (fr) Nouveaux derives cycloaklyles de 1-aryloxy-3-amino-2-propanols, leurs procedes de preparation, et leurs utilisations therapeutiques
BE805437A (fr) Nouveaux derives du 2-amino-(1,2,3,4- tetrahydronaphtalene, leur preparation et leur utilisation
BE846117A (fr) Derives de 1-oxo-isoindoline, leurs procedes de preparation et leur application
FR2285879A1 (fr) Nouveaux derives de guanidine et leur procede de preparation
FR2301241A1 (fr) Nouveaux derives de prostaglandines et leur preparation
BE822937A (fr) Nouveaux derives de 1,3 benzodioxole et leur preparation
FR2340934A1 (fr) Derives de la pyridine, leur preparation et leurs utilisations
BE837595A (fr) Nouveaux derives de nitroimidazole et leur preparation
BE846928A (fr) Derives de la bi-glycoproteine specifique de la grossesse, leur preparation et leurs applications
BE814733A (fr) Derives de 4-benzazinine et leur preparation
BE787307A (fr) Nouveaux derives de la thiazolino-pyrimidinone-5, leur preparation et leurs applications
FR2291205A1 (fr) Nouveaux derives de 7 a-alcoxycephalosporine et leur preparation
BE847475A (fr) Nouveaux derives de la bicyclomycine,

Legal Events

Date Code Title Description
CCPA Application for a supplementary protection certificate

Free format text: 093C0138

CCPV Grant of a supplementary protection certificate

Free format text: 093C0138, EXPIRES 20000411

RE20 Patent expired

Owner name: S.A. NYCOMED CHRISTIAENS

Effective date: 19950411