SE424320B - Analogiforfarande for framstellning av derivat av 3-sulfonamido-4-amino-pyridiner - Google Patents

Analogiforfarande for framstellning av derivat av 3-sulfonamido-4-amino-pyridiner

Info

Publication number
SE424320B
SE424320B SE7504409A SE7504409A SE424320B SE 424320 B SE424320 B SE 424320B SE 7504409 A SE7504409 A SE 7504409A SE 7504409 A SE7504409 A SE 7504409A SE 424320 B SE424320 B SE 424320B
Authority
SE
Sweden
Prior art keywords
sulphonamido
pyridines
amino
preparing derivatives
analogy procedure
Prior art date
Application number
SE7504409A
Other languages
English (en)
Other versions
SE7504409L (sv
Inventor
J E Delarge
C L Lapiere
A H Georges
Original Assignee
Christiaens Sa A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Christiaens Sa A filed Critical Christiaens Sa A
Publication of SE7504409L publication Critical patent/SE7504409L/sv
Publication of SE424320B publication Critical patent/SE424320B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C07D213/71—Sulfur atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
SE7504409A 1974-04-17 1975-04-16 Analogiforfarande for framstellning av derivat av 3-sulfonamido-4-amino-pyridiner SE424320B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1683674A GB1477664A (en) 1974-04-17 1974-04-17 Pyridine derivatives
YU1507/81A YU42409B (en) 1974-04-17 1981-06-15 Process for obtaining new pyridine derivatives

Publications (2)

Publication Number Publication Date
SE7504409L SE7504409L (sv) 1975-10-20
SE424320B true SE424320B (sv) 1982-07-12

Family

ID=26252269

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7504409A SE424320B (sv) 1974-04-17 1975-04-16 Analogiforfarande for framstellning av derivat av 3-sulfonamido-4-amino-pyridiner
SE7907618A SE7907618L (sv) 1974-04-17 1979-09-13 Sett att framstella nya pyridinderivat och anvendning derav som lekemedel

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE7907618A SE7907618L (sv) 1974-04-17 1979-09-13 Sett att framstella nya pyridinderivat och anvendning derav som lekemedel

Country Status (19)

Country Link
US (2) US4018929A (sv)
JP (1) JPS5951536B2 (sv)
AR (4) AR211097A1 (sv)
AT (1) AT344170B (sv)
BE (1) BE827844A (sv)
CA (1) CA1070313A (sv)
CH (3) CH612424A5 (sv)
DD (2) DD121936A5 (sv)
DE (1) DE2516025A1 (sv)
ES (4) ES436581A1 (sv)
FR (1) FR2267775B1 (sv)
GB (1) GB1477664A (sv)
HU (1) HU171420B (sv)
IL (1) IL47084A (sv)
LU (2) LU72284A1 (sv)
NL (2) NL183580C (sv)
SE (2) SE424320B (sv)
YU (1) YU42409B (sv)
ZA (1) ZA752243B (sv)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593609A (en) * 1978-01-31 1981-07-22 Christiaens Sa A Pyridine sulfonamides
US4776878A (en) * 1978-12-04 1988-10-11 E. I. Du Pont De Nemours And Company Agricultural pyridinesulfonamides
LU85193A1 (fr) * 1984-01-31 1985-09-12 Christiaens Sa A Nouveaux derives de la 4-phenylaminopyridine,leur utilisation et leur preparation
DE3529529A1 (de) * 1985-08-17 1987-02-19 Boehringer Mannheim Gmbh Verfahren zur herstellung einer stabilen modifikation von torasemid
US4853389A (en) * 1987-07-24 1989-08-01 American Home Products Corporation Diuretic and antihypertensive substituted-5-pyrimidinesulfonylureas
US4914203A (en) * 1987-07-24 1990-04-03 American Home Products Corporation 5 step process for preparing certain 2,4-diamino-5-pyrimidine-sulfonyl ureas
US5166162A (en) * 1990-03-02 1992-11-24 Adir Et Compagnie Pyridylsulfonylurea and pyridylsulfonylthiourea compounds
FR2659080B1 (fr) * 1990-03-02 1994-07-08 Adir Nouveaux derives de la pyridylsulfonyluree et de la pyridylsulfonylthiouree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5486530A (en) * 1991-04-27 1996-01-23 Boehringer Mannheim Gmbh Use of torasemide for the treatment of brain oedemas
IT1288123B1 (it) * 1996-09-04 1998-09-10 Nicox Sa Uso di nitroderivati per l'incontinenza urinaria
HRP980532B1 (en) 1998-10-02 2005-06-30 Pliva Novel crystalline torasemide modification
US6166045A (en) * 1998-06-02 2000-12-26 Roche Diagnostics Gmbh Torasemide of modification III
US8722668B2 (en) * 1998-12-23 2014-05-13 Daryl W. Hochman Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders
US8008283B2 (en) * 1998-12-23 2011-08-30 Neurotherapeutics Pharma, Inc. Methods and compositions for the treatment of neuropsychiatric disorders
US7214711B2 (en) * 1998-12-23 2007-05-08 Neurotherapeutics Pharma Llc Method of treating migraine headache without aura
EP1207880A4 (en) 1999-08-11 2004-09-01 Teva Pharma TORSEMIDE POLYMORPHS
ES2193007T3 (es) * 2000-02-17 2004-11-01 Teva Pharmaceutical Industries Ltd. Formulacion farmaceutica estable que comprende la modificacion ii de la torsemida.
HRP20000162B1 (en) * 2000-03-20 2004-06-30 Pliva D D Amorphous torasemide modification
EP1741429A3 (en) * 2000-03-20 2007-01-17 Teva Pharmaceutical Industries Ltd. Processes for preparing torsemide
PL370039A1 (en) 2000-03-20 2005-05-16 Teva Pharmaceutical Industries Ltd. Novel processes for preparing torsemide intermediate
HRP20000328A2 (en) * 2000-05-19 2002-02-28 Pliva Farmaceutska Ind Dionik Novel polymorph v of torasemide
US20030022921A1 (en) * 2001-02-21 2003-01-30 Minutza Leibovici Stable pharmaceutical formulation comprising torsemide modification II
IN192178B (sv) 2001-08-03 2004-03-06 Ranbaxy Lab
IL149771A0 (en) * 2002-05-21 2002-11-10 Fintech Lab Ltd Process for preparation of torsemide
HRP20020603B1 (en) * 2002-07-19 2008-11-30 Pliva D.D. New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide
ATE502635T1 (de) 2002-08-19 2011-04-15 Pfizer Kombinationstherapie gegen hyperproliferative erkrankungen
CA2401546C (en) * 2002-09-06 2006-09-19 Brantford Chemicals Inc. Preparation of derivatives of 3-sulfonamido-4-phenylaminopyridine
ITMI20022749A1 (it) * 2002-12-23 2004-06-24 Cosma S P A Nuovo procedimento per la sintesi della tosemide, in particolare della forma ii pura e stabile.
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
US20050215600A1 (en) * 2003-10-27 2005-09-29 Arie Gutman Polymorphs of torsemide hydrochloride and process for production thereof
US7378527B2 (en) * 2004-03-16 2008-05-27 Daqing Che Process for the preparation of torsemide and related intermediates
JP2009511629A (ja) * 2005-10-17 2009-03-19 ニューロセラピューティクス ファーマ， インコーポレイテッド 中枢神経系疾患の調節に有用な利尿薬様化合物類似体
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7625896B2 (en) * 2005-11-25 2009-12-01 Hoffman-La Roche Inc. Pyridylsulfonamide derivatives
US7939532B2 (en) * 2006-10-26 2011-05-10 Hoffmann-La Roche Inc. Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents
WO2008070496A2 (en) 2006-12-01 2008-06-12 Bristol-Myers Squibb Company N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
JP2010526844A (ja) * 2007-05-16 2010-08-05 エフ．ホフマン−ラ ロシュ アーゲー アリールピリジルスルホンアミド誘導体、それらの製造法及び医薬剤としての使用
NL2006622C2 (en) 2011-04-18 2012-10-22 Eurovet Animal Health B V Use of a composition comprising torasemide.
EP2887806B1 (en) 2012-07-20 2019-11-13 University Of Rochester Method of treating and preventing brain impairment using na+-k+ -2ci- cotransporter isoform 1 inhibitors
EP2986599A1 (en) 2013-04-17 2016-02-24 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
PE20180160A1 (es) 2015-02-16 2018-01-18 Univ Queensland Sulfonilureas y compuestos relacionados y uso de estos
LT3661925T (lt) 2017-07-07 2022-03-10 Inflazome Limited Naujieji sulfonamido karboksamido junginiai
US11248001B2 (en) 2019-01-18 2022-02-15 Astrazeneca Ab PCSK9 inhibitors and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3674794A (en) * 1970-03-18 1972-07-04 Ciba Geigy Corp Certain-3-pyridine-sulfonamide derivatives
GB1368948A (en) * 1970-11-11 1974-10-02 Manuf Prod Pharma Pyridine derivatives
US3904636A (en) * 1971-11-09 1975-09-09 Christiaens Sa A 3-sulfonamido-4-phenyl aminopyridines and derivatives
GB1414793A (en) * 1972-07-28 1975-11-19 Manuf Prod Pharma Derivatives of phenylaminopyridine

Also Published As

Publication number Publication date
ES453328A1 (es) 1977-11-01
HU171420B (hu) 1978-01-28
AR211097A1 (es) 1977-10-31
AU8001675A (en) 1976-10-14
BE827844A (fr) 1975-10-13
IL47084A (en) 1979-01-31
JPS50142571A (sv) 1975-11-17
ES453327A1 (es) 1977-11-16
CH609045A5 (sv) 1979-02-15
LU72284A1 (sv) 1975-08-20
ES453329A1 (es) 1977-11-16
DE2516025C2 (sv) 1988-11-03
ES436581A1 (es) 1977-04-01
CA1070313A (en) 1980-01-22
LU88346I2 (fr) 1994-05-04
AT344170B (de) 1978-07-10
FR2267775B1 (sv) 1978-11-10
NL7504521A (nl) 1975-10-21
YU150781A (en) 1984-02-29
AR208770A1 (es) 1977-02-28
NL940014I2 (nl) 1997-04-01
AR208769A1 (es) 1977-02-28
DD126887A5 (sv) 1977-08-17
CH610890A5 (sv) 1979-05-15
JPS5951536B2 (ja) 1984-12-14
DE2516025A1 (de) 1975-11-06
ZA752243B (en) 1976-03-31
FR2267775A1 (sv) 1975-11-14
US4018929A (en) 1977-04-19
SE7504409L (sv) 1975-10-20
AR208768A1 (es) 1977-02-28
CH612424A5 (sv) 1979-07-31
SE7907618L (sv) 1979-09-13
DD121936A5 (sv) 1976-09-05
ATA288275A (de) 1977-11-15
IL47084A0 (en) 1975-06-25
NL183580C (nl) 1988-12-01
NL183580B (nl) 1988-07-01
GB1477664A (en) 1977-06-22
NL940014I1 (nl) 1994-09-16
USRE30633E (en) 1981-06-02
YU42409B (en) 1988-08-31

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