ZA752243B - New derivatives of pyridine - Google Patents

New derivatives of pyridine

Info

Publication number
ZA752243B
ZA752243B ZA00752243A ZA752243A ZA752243B ZA 752243 B ZA752243 B ZA 752243B ZA 00752243 A ZA00752243 A ZA 00752243A ZA 752243 A ZA752243 A ZA 752243A ZA 752243 B ZA752243 B ZA 752243B
Authority
ZA
South Africa
Prior art keywords
pyridine
new derivatives
derivatives
new
Prior art date
Application number
ZA00752243A
Other languages
English (en)
Inventor
J Delarge
C Lapiere
A Georges
Original Assignee
Christiaens Sa A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Christiaens Sa A filed Critical Christiaens Sa A
Publication of ZA752243B publication Critical patent/ZA752243B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C07D213/71—Sulfur atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA00752243A 1974-04-17 1975-04-08 New derivatives of pyridine ZA752243B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1683674A GB1477664A (en) 1974-04-17 1974-04-17 Pyridine derivatives
YU1507/81A YU42409B (en) 1974-04-17 1981-06-15 Process for obtaining new pyridine derivatives

Publications (1)

Publication Number Publication Date
ZA752243B true ZA752243B (en) 1976-03-31

Family

ID=26252269

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00752243A ZA752243B (en) 1974-04-17 1975-04-08 New derivatives of pyridine

Country Status (19)

Country Link
US (2) US4018929A (sv)
JP (1) JPS5951536B2 (sv)
AR (4) AR211097A1 (sv)
AT (1) AT344170B (sv)
BE (1) BE827844A (sv)
CA (1) CA1070313A (sv)
CH (3) CH612424A5 (sv)
DD (2) DD126887A5 (sv)
DE (1) DE2516025A1 (sv)
ES (4) ES436581A1 (sv)
FR (1) FR2267775B1 (sv)
GB (1) GB1477664A (sv)
HU (1) HU171420B (sv)
IL (1) IL47084A (sv)
LU (2) LU72284A1 (sv)
NL (2) NL183580C (sv)
SE (2) SE424320B (sv)
YU (1) YU42409B (sv)
ZA (1) ZA752243B (sv)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593609A (en) * 1978-01-31 1981-07-22 Christiaens Sa A Pyridine sulfonamides
US4776878A (en) * 1978-12-04 1988-10-11 E. I. Du Pont De Nemours And Company Agricultural pyridinesulfonamides
LU85193A1 (fr) * 1984-01-31 1985-09-12 Christiaens Sa A Nouveaux derives de la 4-phenylaminopyridine,leur utilisation et leur preparation
DE3529529A1 (de) * 1985-08-17 1987-02-19 Boehringer Mannheim Gmbh Verfahren zur herstellung einer stabilen modifikation von torasemid
US4914203A (en) * 1987-07-24 1990-04-03 American Home Products Corporation 5 step process for preparing certain 2,4-diamino-5-pyrimidine-sulfonyl ureas
US4853389A (en) * 1987-07-24 1989-08-01 American Home Products Corporation Diuretic and antihypertensive substituted-5-pyrimidinesulfonylureas
FR2659080B1 (fr) * 1990-03-02 1994-07-08 Adir Nouveaux derives de la pyridylsulfonyluree et de la pyridylsulfonylthiouree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5166162A (en) * 1990-03-02 1992-11-24 Adir Et Compagnie Pyridylsulfonylurea and pyridylsulfonylthiourea compounds
US5486530A (en) * 1991-04-27 1996-01-23 Boehringer Mannheim Gmbh Use of torasemide for the treatment of brain oedemas
IT1288123B1 (it) * 1996-09-04 1998-09-10 Nicox Sa Uso di nitroderivati per l'incontinenza urinaria
HRP980532B1 (en) * 1998-10-02 2005-06-30 Pliva Novel crystalline torasemide modification
US6166045A (en) * 1998-06-02 2000-12-26 Roche Diagnostics Gmbh Torasemide of modification III
US7214711B2 (en) * 1998-12-23 2007-05-08 Neurotherapeutics Pharma Llc Method of treating migraine headache without aura
US8722668B2 (en) * 1998-12-23 2014-05-13 Daryl W. Hochman Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders
US8008283B2 (en) * 1998-12-23 2011-08-30 Neurotherapeutics Pharma, Inc. Methods and compositions for the treatment of neuropsychiatric disorders
CA2379322A1 (en) * 1999-08-11 2001-02-15 Teva Pharmaceutical Industries Ltd. Torsemide polymorphs
SK11632003A3 (sk) * 2000-02-17 2004-04-06 Teva Pharmaceutical Industries Ltd. Stabilný farmaceutický prípravok obsahujúci modifikáciu II torsemidu
HRP20000162B1 (en) 2000-03-20 2004-06-30 Pliva D D Amorphous torasemide modification
EP1741429A3 (en) * 2000-03-20 2007-01-17 Teva Pharmaceutical Industries Ltd. Processes for preparing torsemide
CA2403382A1 (en) * 2000-03-20 2001-09-27 Teva Pharmaceutical Industries Ltd. Novel processes for preparing torsemide intermediate
HRP20000328A2 (en) 2000-05-19 2002-02-28 Pliva Farmaceutska Ind Dionik Novel polymorph v of torasemide
US20030022921A1 (en) * 2001-02-21 2003-01-30 Minutza Leibovici Stable pharmaceutical formulation comprising torsemide modification II
IN192178B (sv) 2001-08-03 2004-03-06 Ranbaxy Lab
IL149771A0 (en) * 2002-05-21 2002-11-10 Fintech Lab Ltd Process for preparation of torsemide
HRP20020603B1 (en) * 2002-07-19 2008-11-30 Pliva D.D. New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide
AP2005003232A0 (en) 2002-08-19 2005-03-31 Pfizer Prod Inc Combination therapy for hyperproliferative diseases.
CA2401546C (en) * 2002-09-06 2006-09-19 Brantford Chemicals Inc. Preparation of derivatives of 3-sulfonamido-4-phenylaminopyridine
ITMI20022749A1 (it) * 2002-12-23 2004-06-24 Cosma S P A Nuovo procedimento per la sintesi della tosemide, in particolare della forma ii pura e stabile.
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
US20050215600A1 (en) * 2003-10-27 2005-09-29 Arie Gutman Polymorphs of torsemide hydrochloride and process for production thereof
US7378527B2 (en) * 2004-03-16 2008-05-27 Daqing Che Process for the preparation of torsemide and related intermediates
US20070149526A1 (en) * 2005-10-17 2007-06-28 Neurotherapeutics Pharma, L.L.C. Diuretic and diuretic-like compound analogs
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7625896B2 (en) * 2005-11-25 2009-12-01 Hoffman-La Roche Inc. Pyridylsulfonamide derivatives
US7939532B2 (en) * 2006-10-26 2011-05-10 Hoffmann-La Roche Inc. Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents
US8404896B2 (en) 2006-12-01 2013-03-26 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases
CN101675033A (zh) * 2007-05-16 2010-03-17 霍夫曼-拉罗奇有限公司 芳基吡啶基磺酰胺衍生物，它们的制备和作为药剂的应用
NL2006622C2 (en) 2011-04-18 2012-10-22 Eurovet Animal Health B V Use of a composition comprising torasemide.
WO2014014519A1 (en) 2012-07-20 2014-01-23 University Of Rochester Method of treating and preventing brain impairment using na+-k+ -2ci- cotransporter isoform 1 inhibitors
BR112015026513A2 (pt) 2013-04-17 2017-07-25 Pfizer derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
EP3578547B1 (en) * 2015-02-16 2021-05-26 The University of Queensland Sulfonylureas and related compounds and use of same
WO2019008025A1 (en) 2017-07-07 2019-01-10 Inflazome Limited NOVEL CARBOXAMIDE SULFONAMIDE COMPOUNDS
MX2021008533A (es) 2019-01-18 2021-08-19 Astrazeneca Ab Inhibidores de la pcsk9 y metodos de uso de los mismos.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3674794A (en) * 1970-03-18 1972-07-04 Ciba Geigy Corp Certain-3-pyridine-sulfonamide derivatives
GB1368948A (en) * 1970-11-11 1974-10-02 Manuf Prod Pharma Pyridine derivatives
GB1414793A (en) * 1972-07-28 1975-11-19 Manuf Prod Pharma Derivatives of phenylaminopyridine
US3904636A (en) * 1971-11-09 1975-09-09 Christiaens Sa A 3-sulfonamido-4-phenyl aminopyridines and derivatives

Also Published As

Publication number Publication date
NL7504521A (nl) 1975-10-21
AR211097A1 (es) 1977-10-31
NL183580C (nl) 1988-12-01
ES436581A1 (es) 1977-04-01
DE2516025C2 (sv) 1988-11-03
CH612424A5 (sv) 1979-07-31
HU171420B (hu) 1978-01-28
LU88346I2 (fr) 1994-05-04
ES453329A1 (es) 1977-11-16
ES453328A1 (es) 1977-11-01
SE7907618L (sv) 1979-09-13
DD126887A5 (sv) 1977-08-17
JPS5951536B2 (ja) 1984-12-14
NL940014I2 (nl) 1997-04-01
AT344170B (de) 1978-07-10
CH609045A5 (sv) 1979-02-15
NL940014I1 (nl) 1994-09-16
ATA288275A (de) 1977-11-15
AR208770A1 (es) 1977-02-28
USRE30633E (en) 1981-06-02
AR208769A1 (es) 1977-02-28
SE7504409L (sv) 1975-10-20
CA1070313A (en) 1980-01-22
SE424320B (sv) 1982-07-12
DD121936A5 (sv) 1976-09-05
AR208768A1 (es) 1977-02-28
YU150781A (en) 1984-02-29
FR2267775A1 (sv) 1975-11-14
AU8001675A (en) 1976-10-14
DE2516025A1 (de) 1975-11-06
GB1477664A (en) 1977-06-22
NL183580B (nl) 1988-07-01
ES453327A1 (es) 1977-11-16
FR2267775B1 (sv) 1978-11-10
BE827844A (fr) 1975-10-13
IL47084A (en) 1979-01-31
US4018929A (en) 1977-04-19
CH610890A5 (sv) 1979-05-15
YU42409B (en) 1988-08-31
JPS50142571A (sv) 1975-11-17
IL47084A0 (en) 1975-06-25
LU72284A1 (sv) 1975-08-20

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