SE424320B - Analogiforfarande for framstellning av derivat av 3-sulfonamido-4-amino-pyridiner - Google Patents
Analogiforfarande for framstellning av derivat av 3-sulfonamido-4-amino-pyridinerInfo
- Publication number
- SE424320B SE424320B SE7504409A SE7504409A SE424320B SE 424320 B SE424320 B SE 424320B SE 7504409 A SE7504409 A SE 7504409A SE 7504409 A SE7504409 A SE 7504409A SE 424320 B SE424320 B SE 424320B
- Authority
- SE
- Sweden
- Prior art keywords
- sulphonamido
- pyridines
- amino
- preparing derivatives
- analogy procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- C07D213/71—Sulfur atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1683674A GB1477664A (en) | 1974-04-17 | 1974-04-17 | Pyridine derivatives |
| YU1507/81A YU42409B (en) | 1974-04-17 | 1981-06-15 | Process for obtaining new pyridine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7504409L SE7504409L (sv) | 1975-10-20 |
| SE424320B true SE424320B (sv) | 1982-07-12 |
Family
ID=26252269
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7504409A SE424320B (sv) | 1974-04-17 | 1975-04-16 | Analogiforfarande for framstellning av derivat av 3-sulfonamido-4-amino-pyridiner |
| SE7907618A SE7907618L (sv) | 1974-04-17 | 1979-09-13 | Sett att framstella nya pyridinderivat och anvendning derav som lekemedel |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7907618A SE7907618L (sv) | 1974-04-17 | 1979-09-13 | Sett att framstella nya pyridinderivat och anvendning derav som lekemedel |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US4018929A (fr) |
| JP (1) | JPS5951536B2 (fr) |
| AR (4) | AR211097A1 (fr) |
| AT (1) | AT344170B (fr) |
| BE (1) | BE827844A (fr) |
| CA (1) | CA1070313A (fr) |
| CH (3) | CH612424A5 (fr) |
| DD (2) | DD121936A5 (fr) |
| DE (1) | DE2516025A1 (fr) |
| ES (4) | ES436581A1 (fr) |
| FR (1) | FR2267775B1 (fr) |
| GB (1) | GB1477664A (fr) |
| HU (1) | HU171420B (fr) |
| IL (1) | IL47084A (fr) |
| LU (2) | LU72284A1 (fr) |
| NL (2) | NL183580C (fr) |
| SE (2) | SE424320B (fr) |
| YU (1) | YU42409B (fr) |
| ZA (1) | ZA752243B (fr) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1593609A (en) * | 1978-01-31 | 1981-07-22 | Christiaens Sa A | Pyridine sulfonamides |
| US4776878A (en) * | 1978-12-04 | 1988-10-11 | E. I. Du Pont De Nemours And Company | Agricultural pyridinesulfonamides |
| LU85193A1 (fr) * | 1984-01-31 | 1985-09-12 | Christiaens Sa A | Nouveaux derives de la 4-phenylaminopyridine,leur utilisation et leur preparation |
| DE3529529A1 (de) * | 1985-08-17 | 1987-02-19 | Boehringer Mannheim Gmbh | Verfahren zur herstellung einer stabilen modifikation von torasemid |
| US4914203A (en) * | 1987-07-24 | 1990-04-03 | American Home Products Corporation | 5 step process for preparing certain 2,4-diamino-5-pyrimidine-sulfonyl ureas |
| US4853389A (en) * | 1987-07-24 | 1989-08-01 | American Home Products Corporation | Diuretic and antihypertensive substituted-5-pyrimidinesulfonylureas |
| US5166162A (en) * | 1990-03-02 | 1992-11-24 | Adir Et Compagnie | Pyridylsulfonylurea and pyridylsulfonylthiourea compounds |
| FR2659080B1 (fr) * | 1990-03-02 | 1994-07-08 | Adir | Nouveaux derives de la pyridylsulfonyluree et de la pyridylsulfonylthiouree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5486530A (en) * | 1991-04-27 | 1996-01-23 | Boehringer Mannheim Gmbh | Use of torasemide for the treatment of brain oedemas |
| IT1288123B1 (it) * | 1996-09-04 | 1998-09-10 | Nicox Sa | Uso di nitroderivati per l'incontinenza urinaria |
| HRP980532B1 (en) * | 1998-10-02 | 2005-06-30 | Pliva | Novel crystalline torasemide modification |
| US6166045A (en) * | 1998-06-02 | 2000-12-26 | Roche Diagnostics Gmbh | Torasemide of modification III |
| US8008283B2 (en) * | 1998-12-23 | 2011-08-30 | Neurotherapeutics Pharma, Inc. | Methods and compositions for the treatment of neuropsychiatric disorders |
| US7214711B2 (en) * | 1998-12-23 | 2007-05-08 | Neurotherapeutics Pharma Llc | Method of treating migraine headache without aura |
| US8722668B2 (en) * | 1998-12-23 | 2014-05-13 | Daryl W. Hochman | Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders |
| SI20816A (sl) * | 1999-08-11 | 2002-08-31 | Teva Pharmaceutical Industries Ltd. | Polimorfi torsemid-a |
| CA2410802A1 (fr) * | 2000-02-17 | 2002-09-06 | Minutza Leibovici | Formulation pharmaceutique stable contenant du torsemide modification ii |
| HRP20000162B1 (en) * | 2000-03-20 | 2004-06-30 | Pliva D D | Amorphous torasemide modification |
| EP1741429A3 (fr) * | 2000-03-20 | 2007-01-17 | Teva Pharmaceutical Industries Ltd. | Procédé pour la préparation de torsemide |
| WO2001070226A1 (fr) | 2000-03-20 | 2001-09-27 | Teva Pharmaceutical Industries Ltd. | Nouveaux procedes de preparation d'un intermediaire de torsemide |
| HRP20000328A2 (en) * | 2000-05-19 | 2002-02-28 | Pliva Farmaceutska Ind Dionik | Novel polymorph v of torasemide |
| US20030022921A1 (en) * | 2001-02-21 | 2003-01-30 | Minutza Leibovici | Stable pharmaceutical formulation comprising torsemide modification II |
| IN192178B (fr) | 2001-08-03 | 2004-03-06 | Ranbaxy Lab | |
| IL149771A0 (en) * | 2002-05-21 | 2002-11-10 | Fintech Lab Ltd | Process for preparation of torsemide |
| HRP20020603B1 (en) * | 2002-07-19 | 2008-11-30 | Pliva D.D. | New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide |
| AP2005003232A0 (en) | 2002-08-19 | 2005-03-31 | Pfizer Prod Inc | Combination therapy for hyperproliferative diseases. |
| CA2401546C (fr) * | 2002-09-06 | 2006-09-19 | Brantford Chemicals Inc. | Synthese de derives de la 3-sulfonamido-4-phenylaminopyridine |
| ITMI20022749A1 (it) * | 2002-12-23 | 2004-06-24 | Cosma S P A | Nuovo procedimento per la sintesi della tosemide, in particolare della forma ii pura e stabile. |
| US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
| US20050215600A1 (en) * | 2003-10-27 | 2005-09-29 | Arie Gutman | Polymorphs of torsemide hydrochloride and process for production thereof |
| US7378527B2 (en) * | 2004-03-16 | 2008-05-27 | Daqing Che | Process for the preparation of torsemide and related intermediates |
| WO2007047447A2 (fr) * | 2005-10-17 | 2007-04-26 | Neurotherapeutics Pharma, Inc. | Analogues de compose diuretique ou de type diuretique |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| US7625896B2 (en) * | 2005-11-25 | 2009-12-01 | Hoffman-La Roche Inc. | Pyridylsulfonamide derivatives |
| US7939532B2 (en) * | 2006-10-26 | 2011-05-10 | Hoffmann-La Roche Inc. | Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents |
| ES2382009T3 (es) | 2006-12-01 | 2012-06-04 | Bristol-Myers Squibb Company | Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares |
| US7879884B2 (en) * | 2007-05-16 | 2011-02-01 | Hoffmann-La Roche Inc. | Aryl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents |
| NL2006622C2 (en) | 2011-04-18 | 2012-10-22 | Eurovet Animal Health B V | Use of a composition comprising torasemide. |
| EP2887806B1 (fr) | 2012-07-20 | 2019-11-13 | University Of Rochester | Méthode de traitement et de prévention d'une atteinte cérébrale faisant appel à des inhibiteurs de l'isoforme 1 du cotransporteur na+-k+ -2ci |
| CN105143203A (zh) | 2013-04-17 | 2015-12-09 | 辉瑞大药厂 | 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物 |
| WO2016055901A1 (fr) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Composés d'amide substitué |
| MD3259253T2 (ro) * | 2015-02-16 | 2020-06-30 | Univ Queensland | Sulfoniluree și compuși înrudiți și utilizări ale acestora |
| ES2906280T3 (es) | 2017-07-07 | 2022-04-18 | Inflazome Ltd | Nuevos compuestos de sulfonamida carboxamida |
| WO2020150473A2 (fr) | 2019-01-18 | 2020-07-23 | Dogma Therapeutics, Inc. | Inhibiteurs de pcsk9 et leurs procédés d'utilisation |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3674794A (en) * | 1970-03-18 | 1972-07-04 | Ciba Geigy Corp | Certain-3-pyridine-sulfonamide derivatives |
| GB1368948A (en) * | 1970-11-11 | 1974-10-02 | Manuf Prod Pharma | Pyridine derivatives |
| GB1414793A (en) * | 1972-07-28 | 1975-11-19 | Manuf Prod Pharma | Derivatives of phenylaminopyridine |
| US3904636A (en) * | 1971-11-09 | 1975-09-09 | Christiaens Sa A | 3-sulfonamido-4-phenyl aminopyridines and derivatives |
-
1974
- 1974-04-17 GB GB1683674A patent/GB1477664A/en not_active Expired
-
1975
- 1975-04-08 ZA ZA00752243A patent/ZA752243B/xx unknown
- 1975-04-11 BE BE155330A patent/BE827844A/fr not_active IP Right Cessation
- 1975-04-12 DE DE19752516025 patent/DE2516025A1/de active Granted
- 1975-04-14 ES ES436581A patent/ES436581A1/es not_active Expired
- 1975-04-14 HU HU75CI00001569A patent/HU171420B/hu unknown
- 1975-04-14 IL IL47084A patent/IL47084A/xx unknown
- 1975-04-15 LU LU72284A patent/LU72284A1/xx unknown
- 1975-04-16 NL NLAANVRAGE7504521,A patent/NL183580C/xx active Protection Beyond IP Right Term
- 1975-04-16 FR FR7511791A patent/FR2267775B1/fr not_active Expired
- 1975-04-16 CA CA224,805A patent/CA1070313A/fr not_active Expired
- 1975-04-16 CH CH216478A patent/CH612424A5/xx not_active IP Right Cessation
- 1975-04-16 SE SE7504409A patent/SE424320B/xx unknown
- 1975-04-16 CH CH485775A patent/CH609045A5/xx active Protection Beyond IP Right Term
- 1975-04-16 CH CH216378A patent/CH610890A5/xx active Protection Beyond IP Right Term
- 1975-04-16 US US05/568,759 patent/US4018929A/en not_active Expired - Lifetime
- 1975-04-16 AT AT288275A patent/AT344170B/de not_active IP Right Cessation
- 1975-04-17 AR AR258409A patent/AR211097A1/es active
- 1975-04-17 JP JP50047371A patent/JPS5951536B2/ja not_active Expired
- 1975-04-17 DD DD185508A patent/DD121936A5/xx unknown
- 1975-04-17 DD DD194800A patent/DD126887A5/xx unknown
-
1976
- 1976-03-19 AR AR262625A patent/AR208768A1/es active
- 1976-03-19 AR AR262626A patent/AR208769A1/es active
- 1976-03-19 AR AR262627A patent/AR208770A1/es active
- 1976-11-15 ES ES453329A patent/ES453329A1/es not_active Expired
- 1976-11-15 ES ES453328A patent/ES453328A1/es not_active Expired
- 1976-11-15 ES ES453327A patent/ES453327A1/es not_active Expired
-
1979
- 1979-09-13 SE SE7907618A patent/SE7907618L/sv not_active Application Discontinuation
-
1980
- 1980-02-07 US US06/119,601 patent/USRE30633E/en not_active Expired - Lifetime
-
1981
- 1981-06-15 YU YU1507/81A patent/YU42409B/xx unknown
-
1993
- 1993-06-30 LU LU88346C patent/LU88346I2/fr unknown
-
1994
- 1994-07-27 NL NL940014C patent/NL940014I2/nl unknown
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