FR05C0032I1 - - Google Patents
Info
- Publication number
- FR05C0032I1 FR05C0032I1 FR05C0032C FR05C0032I1 FR 05C0032 I1 FR05C0032 I1 FR 05C0032I1 FR 05C0032 C FR05C0032 C FR 05C0032C FR 05C0032 I1 FR05C0032 I1 FR 05C0032I1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Oscillators With Electromechanical Resonators (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68683896A | 1996-07-26 | 1996-07-26 | |
PCT/US1997/013244 WO1998004569A1 (en) | 1996-07-26 | 1997-07-25 | Nucleotide analogs |
Publications (2)
Publication Number | Publication Date |
---|---|
FR05C0032I1 true FR05C0032I1 (pl) | 2005-08-26 |
FR05C0032I2 FR05C0032I2 (fr) | 2006-12-29 |
Family
ID=24757965
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR05C0032C Active FR05C0032I2 (fr) | 1996-07-26 | 2005-07-19 | Analogues de nucleotides |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0915894B1 (pl) |
KR (1) | KR100619298B1 (pl) |
CN (2) | CN101239989B (pl) |
AT (1) | ATE240339T1 (pl) |
AU (1) | AU713374B2 (pl) |
DE (3) | DE69722004T2 (pl) |
DK (1) | DK0915894T3 (pl) |
ES (1) | ES2198003T3 (pl) |
FR (1) | FR05C0032I2 (pl) |
HK (1) | HK1020964A1 (pl) |
LU (2) | LU91178I2 (pl) |
NL (2) | NL300202I1 (pl) |
NZ (1) | NZ333687A (pl) |
PT (1) | PT915894E (pl) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100396689C (zh) * | 2006-03-07 | 2008-06-25 | 中国医学科学院医药生物技术研究所 | 一组具有抑制hiv-1/hbv病毒复制活性的替诺福韦单酯化合物 |
CN102453055B (zh) * | 2010-10-29 | 2015-04-01 | 上海迪赛诺医药发展有限公司 | 制备(r)-9-(2-膦酰甲氧基丙基)腺嘌呤双(异丙氧羰基氧甲基)酯的方法 |
CN102887901B (zh) * | 2011-07-01 | 2015-01-07 | 四川好医生攀西药业有限责任公司 | 无环核苷酸类似物及其制备方法和应用 |
US8754065B2 (en) | 2011-08-16 | 2014-06-17 | Gilead Sciences, Inc. | Tenofovir alafenamide hemifumarate |
CN103232490B (zh) * | 2013-01-31 | 2015-06-10 | 洛阳聚慧投资股份有限公司 | 具有抑制hiv-1/hbv病毒复制活性的核苷类化合物、制备方法及抗病毒方面的应用 |
CN103242366B (zh) * | 2012-08-13 | 2014-08-20 | 洛阳聚慧投资股份有限公司 | 一组替诺福韦酯化合物、制备方法及其在抗病毒方面的应用 |
CN104230934B (zh) * | 2013-06-08 | 2016-12-28 | 上海医药工业研究院 | 一种化合物及其制备方法和用途 |
EP2860184B1 (en) | 2013-10-09 | 2018-08-29 | Zentiva, k.s. | Dihydrogenphosphate salt of Tenofovir disoproxil |
CN104844459B (zh) * | 2014-02-18 | 2016-08-24 | 扬州三友合成化工有限公司 | 一种氯甲基异丙基碳酸酯的制备方法 |
CN103880884A (zh) * | 2014-03-21 | 2014-06-25 | 浙江苏泊尔制药有限公司 | 一种高纯度富马酸泰诺福韦酯的制备方法 |
CN104098605B (zh) * | 2014-07-30 | 2015-09-30 | 福建广生堂药业股份有限公司 | 一种适合于工业化生产的替诺福韦制备方法 |
KR101703257B1 (ko) | 2014-09-30 | 2017-02-06 | 한미정밀화학주식회사 | 고순도의 (r)-9-[2-(포스포노메톡시)프로필]아데닌의 제조방법 |
KR101703258B1 (ko) | 2014-12-30 | 2017-02-06 | 한미정밀화학주식회사 | 고순도의 (r)-9-[2-(포스포노메톡시)프로필]아데닌의 제조방법 |
CN105985381B (zh) * | 2014-12-30 | 2018-10-30 | 安徽贝克联合制药有限公司 | 一种替诺福韦的制备方法 |
KR101761466B1 (ko) * | 2015-01-20 | 2017-07-26 | 씨제이헬스케어 주식회사 | 신규한 테노포비어 디소프록실 캠실레이트, 이의 결정형 및 이의 제조방법 |
CN106349289A (zh) * | 2016-08-03 | 2017-01-25 | 上海延安药业有限公司 | 替诺福韦酯原料药及片剂 |
KR101909570B1 (ko) * | 2016-12-05 | 2018-10-19 | (주) 성운파마코피아 | 고순도 테노포비어 디소프록실 제조방법 |
CN108358968B (zh) * | 2018-04-03 | 2020-09-15 | 科兴生物制药股份有限公司 | 一种替诺福韦的制备方法 |
KR20220141457A (ko) | 2021-04-13 | 2022-10-20 | 경동제약 주식회사 | 신규 결정형의 테노포비어 알라펜아미드 말레산염 및 이를 포함하는 약제학적 조성물 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0054512A3 (de) * | 1980-12-12 | 1983-08-03 | Ciba-Geigy Ag | Cephalosporinester, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate |
CS263951B1 (en) * | 1985-04-25 | 1989-05-12 | Antonin Holy | 9-(phosponylmethoxyalkyl)adenines and method of their preparation |
EP0481214B1 (en) * | 1990-09-14 | 1998-06-24 | Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic | Prodrugs of phosphonates |
CA2054126A1 (en) * | 1990-10-26 | 1992-04-27 | Michiyuki Sendai | Cephem compounds, their production and use |
US6057305A (en) * | 1992-08-05 | 2000-05-02 | Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic | Antiretroviral enantiomeric nucleotide analogs |
WO1995032957A1 (en) * | 1994-05-27 | 1995-12-07 | Astra Aktiebolag | Novel ethoxycarbonyloxymethyl derivatives of substituted benzimidazoles |
-
1997
- 1997-07-25 ES ES97936257T patent/ES2198003T3/es not_active Expired - Lifetime
- 1997-07-25 CN CN2008100832337A patent/CN101239989B/zh not_active Expired - Lifetime
- 1997-07-25 DE DE69722004T patent/DE69722004T2/de not_active Expired - Lifetime
- 1997-07-25 AT AT97936257T patent/ATE240339T1/de active
- 1997-07-25 PT PT97936257T patent/PT915894E/pt unknown
- 1997-07-25 DK DK97936257T patent/DK0915894T3/da active
- 1997-07-25 DE DE122008000033C patent/DE122008000033I1/de active Pending
- 1997-07-25 KR KR1019997000806A patent/KR100619298B1/ko not_active IP Right Cessation
- 1997-07-25 NZ NZ333687A patent/NZ333687A/xx not_active IP Right Cessation
- 1997-07-25 CN CNB971974608A patent/CN100384859C/zh not_active Expired - Lifetime
- 1997-07-25 EP EP97936257A patent/EP0915894B1/en not_active Expired - Lifetime
- 1997-07-25 DE DE200512000041 patent/DE122005000041I2/de active Active
- 1997-07-25 AU AU38970/97A patent/AU713374B2/en not_active Expired
-
1999
- 1999-11-19 HK HK99105370A patent/HK1020964A1/xx not_active IP Right Cessation
-
2005
- 2005-06-22 LU LU91178C patent/LU91178I2/fr unknown
- 2005-07-13 NL NL300202C patent/NL300202I1/nl unknown
- 2005-07-19 FR FR05C0032C patent/FR05C0032I2/fr active Active
-
2008
- 2008-04-30 LU LU91433C patent/LU91433I2/fr unknown
- 2008-05-13 NL NL300344C patent/NL300344I1/nl unknown
Also Published As
Publication number | Publication date |
---|---|
FR05C0032I2 (fr) | 2006-12-29 |
DE122005000041I2 (de) | 2012-05-24 |
CN101239989A (zh) | 2008-08-13 |
AU713374B2 (en) | 1999-12-02 |
DE122005000041I1 (de) | 2005-10-20 |
HK1020964A1 (en) | 2000-05-26 |
EP0915894B1 (en) | 2003-05-14 |
CN100384859C (zh) | 2008-04-30 |
NL300344I1 (nl) | 2008-07-01 |
ES2198003T3 (es) | 2004-01-16 |
DE69722004D1 (de) | 2003-06-18 |
KR100619298B1 (ko) | 2006-09-08 |
KR20000029705A (ko) | 2000-05-25 |
DK0915894T3 (da) | 2003-09-15 |
LU91178I2 (fr) | 2005-08-22 |
NL300202I1 (nl) | 2005-09-01 |
LU91178I9 (pl) | 2018-12-28 |
CN1244200A (zh) | 2000-02-09 |
LU91433I2 (fr) | 2008-06-30 |
NZ333687A (en) | 2000-08-25 |
EP0915894A1 (en) | 1999-05-19 |
DE122008000033I1 (de) | 2008-10-02 |
CN101239989B (zh) | 2012-12-12 |
AU3897097A (en) | 1998-02-20 |
DE69722004T2 (de) | 2004-04-01 |
PT915894E (pt) | 2003-10-31 |
ATE240339T1 (de) | 2003-05-15 |