FI980901A - Orala sammansättningar som kontrollerat frigör levosimendan - Google Patents

Orala sammansättningar som kontrollerat frigör levosimendan

Info

Publication number
FI980901A
FI980901A FI980901A FI980901A FI980901A FI 980901 A FI980901 A FI 980901A FI 980901 A FI980901 A FI 980901A FI 980901 A FI980901 A FI 980901A FI 980901 A FI980901 A FI 980901A
Authority
FI
Finland
Prior art keywords
levosimendan
controlled release
oral compositions
oral
compositions
Prior art date
Application number
FI980901A
Other languages
English (en)
Finnish (fi)
Other versions
FI980901A0 (sv
Inventor
Maarit Harjula
Ilkka Larma
Saila Antila
Lasse Lehtonen
Original Assignee
Orion Yhtymae Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8551575&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI980901(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orion Yhtymae Oyj filed Critical Orion Yhtymae Oyj
Priority to FI980901A priority Critical patent/FI980901A/sv
Publication of FI980901A0 publication Critical patent/FI980901A0/sv
Priority to CO99018533A priority patent/CO5070607A1/es
Priority to TW088105661A priority patent/TWI224507B/zh
Priority to ARP990101869A priority patent/AR019096A1/es
Priority to EEP200000617A priority patent/EE04220B1/xx
Priority to JP2000545505A priority patent/JP4566402B2/ja
Priority to CNB998064181A priority patent/CN1248691C/zh
Priority to IDW20002367A priority patent/ID27987A/id
Priority to UA2000116616A priority patent/UA68376C2/uk
Priority to IL13895199A priority patent/IL138951A0/xx
Priority to US09/673,794 priority patent/US7045147B1/en
Priority to ES99916941T priority patent/ES2215379T3/es
Priority to AU35246/99A priority patent/AU756641B2/en
Priority to TR2000/03102T priority patent/TR200003102T2/xx
Priority to DE69914472T priority patent/DE69914472T2/de
Priority to HU0101458A priority patent/HUP0101458A3/hu
Priority to NZ507453A priority patent/NZ507453A/xx
Priority to GEAP19995639A priority patent/GEP20032906B/en
Priority to PL344078A priority patent/PL197447B1/pl
Priority to SI9930536T priority patent/SI1071397T1/xx
Priority to CZ20003780A priority patent/CZ295194B6/cs
Priority to MXPA00010367A priority patent/MXPA00010367A/es
Priority to YUP-639/00A priority patent/RS49962B/sr
Priority to DK99916941T priority patent/DK1071397T3/da
Priority to SK1554-2000A priority patent/SK285427B6/sk
Priority to EA200001098A priority patent/EA002829B1/ru
Priority to BR9909869-5A priority patent/BR9909869A/pt
Priority to PT99916941T priority patent/PT1071397E/pt
Priority to PCT/FI1999/000329 priority patent/WO1999055305A2/en
Priority to EP99916941A priority patent/EP1071397B1/en
Priority to CA002329234A priority patent/CA2329234C/en
Priority to AT99916941T priority patent/ATE258425T1/de
Priority to KR1020007011788A priority patent/KR100960597B1/ko
Publication of FI980901A publication Critical patent/FI980901A/sv
Priority to IL138951A priority patent/IL138951A/en
Priority to ZA200005632A priority patent/ZA200005632B/en
Priority to HR20000704A priority patent/HRP20000704B1/xx
Priority to NO20005313A priority patent/NO329809B1/no
Priority to BG104959A priority patent/BG64839B1/bg
Priority to HK01101050A priority patent/HK1034032A1/xx
Priority to JP2010004367A priority patent/JP2010083900A/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
FI980901A 1998-04-23 1998-04-23 Orala sammansättningar som kontrollerat frigör levosimendan FI980901A (sv)

Priority Applications (40)

Application Number Priority Date Filing Date Title
FI980901A FI980901A (sv) 1998-04-23 1998-04-23 Orala sammansättningar som kontrollerat frigör levosimendan
CO99018533A CO5070607A1 (es) 1998-04-23 1999-03-26 Composiciones perorales de liberacion controlada de levosimendan o (-)-[[4-(1,4,5,6-tetrahidro-4-metil-6-oxo-3- pirazinil) fenil] -hidrazono]propanodinitrilo
TW088105661A TWI224507B (en) 1998-04-23 1999-04-09 Controlled release peroral compositions of levosimendan
ARP990101869A AR019096A1 (es) 1998-04-23 1999-04-22 Composicion de liberacion controlada que comprende levosimendan y un polimero que forma gel hidrofilico
AT99916941T ATE258425T1 (de) 1998-04-23 1999-04-23 Levosimendanhaltige oral anzuwendende arzneimittel mit gesteuerter wirkstoffverabreichung
KR1020007011788A KR100960597B1 (ko) 1998-04-23 1999-04-23 레보시멘단의 조절 방출성 경구 조성물
SI9930536T SI1071397T1 (en) 1998-04-23 1999-04-23 Controlled release peroral compositions of levosimendan
DK99916941T DK1071397T3 (da) 1998-04-23 1999-04-23 Levosimendan-holdige lægemidler til oral indgivelse med kontrolleret frisætning af det aktive middel
CNB998064181A CN1248691C (zh) 1998-04-23 1999-04-23 左西孟旦控释口服组合物
IDW20002367A ID27987A (id) 1998-04-23 1999-04-23 Komposisi-komposisi peroral levosimendan pelepasan terkontrol
UA2000116616A UA68376C2 (en) 1998-04-23 1999-04-23 Peroral pharmaceutical composition with controlled release of levosimendan (variants)
IL13895199A IL138951A0 (en) 1998-04-23 1999-04-23 Controlled release peroral compositions of levosimendan
US09/673,794 US7045147B1 (en) 1998-04-23 1999-04-23 Controlled release peroral compositions of levosimendan
ES99916941T ES2215379T3 (es) 1998-04-23 1999-04-23 Composiciones perorales de levosimendan de liberacion controlada.
AU35246/99A AU756641B2 (en) 1998-04-23 1999-04-23 Controlled release peroral compositions of levosimendan
TR2000/03102T TR200003102T2 (tr) 1998-04-23 1999-04-23 Levosimendanın Kontrollü Salınan Peroral Kompozisyonları
DE69914472T DE69914472T2 (de) 1998-04-23 1999-04-23 Levosimendanhaltige oral anzuwendende arzneimittel mit gesteuerter wirkstoffverabreichung
HU0101458A HUP0101458A3 (en) 1998-04-23 1999-04-23 Controlled release peroral compositions of levosimendan
NZ507453A NZ507453A (en) 1998-04-23 1999-04-23 Oral sustained release compositions of levosimendan with a hydrophilic gel forming polymer
GEAP19995639A GEP20032906B (en) 1998-04-23 1999-04-23 Controlled Release Peroral Pharmaceutical Composition of Levosimendan for Treatment of Congestive Heart Failure
PL344078A PL197447B1 (pl) 1998-04-23 1999-04-23 Kompozycje lewosimendanu o kontrolowanym uwalnianiu do podawania doustnego
EEP200000617A EE04220B1 (et) 1998-04-23 1999-04-23 Kontrollitud vabanemisega levosimendani peroraalsed koostised
CZ20003780A CZ295194B6 (cs) 1998-04-23 1999-04-23 Orální prostředky s řízeným uvolňováním obsahující levosimendan
MXPA00010367A MXPA00010367A (es) 1998-04-23 1999-04-23 Composiciones de levosimendan perorales de liberacion controlada.
YUP-639/00A RS49962B (sr) 1998-04-23 1999-04-23 Peroralne kompozicije koje kontrolisano oslobađaju levosimendan
JP2000545505A JP4566402B2 (ja) 1998-04-23 1999-04-23 レボシメンダンの制御放出経口用組成物
SK1554-2000A SK285427B6 (sk) 1998-04-23 1999-04-23 Prostriedky na orálne podanie s riadeným uvoľňovaním levosimendanu
EA200001098A EA002829B1 (ru) 1998-04-23 1999-04-23 Пероральные композиции с контролируемым высвобождением левозимендана
BR9909869-5A BR9909869A (pt) 1998-04-23 1999-04-23 Composições perorais de liberação controlada de levosimendan
PT99916941T PT1071397E (pt) 1998-04-23 1999-04-23 Composicoes perorais de libertacao controlada de levosimendan
PCT/FI1999/000329 WO1999055305A2 (en) 1998-04-23 1999-04-23 Controlled release peroral compositions of levosimendan
EP99916941A EP1071397B1 (en) 1998-04-23 1999-04-23 Controlled release peroral compositions of levosimendan
CA002329234A CA2329234C (en) 1998-04-23 1999-04-23 Controlled release peroral compositions of levosimendan
IL138951A IL138951A (en) 1998-04-23 2000-10-11 Controlled release of Froel Malbusmandan
ZA200005632A ZA200005632B (en) 1998-04-23 2000-10-12 Controlled release peroral compositions of levosimendan.
HR20000704A HRP20000704B1 (en) 1998-04-23 2000-10-19 Controlled release peroral compositions of levosimendan
NO20005313A NO329809B1 (no) 1998-04-23 2000-10-20 Perorale sammensetninger av levosimendan med kontrollert frigjoring
BG104959A BG64839B1 (bg) 1998-04-23 2000-11-17 Контролирано освобождаващи перорални състави на левосимендан
HK01101050A HK1034032A1 (en) 1998-04-23 2001-02-14 Controlled release peroral compositions of levosimendan
JP2010004367A JP2010083900A (ja) 1998-04-23 2010-01-12 レボシメンダンの制御放出経口用組成物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI980901A FI980901A (sv) 1998-04-23 1998-04-23 Orala sammansättningar som kontrollerat frigör levosimendan

Publications (2)

Publication Number Publication Date
FI980901A0 FI980901A0 (sv) 1998-04-23
FI980901A true FI980901A (sv) 1999-10-24

Family

ID=8551575

Family Applications (1)

Application Number Title Priority Date Filing Date
FI980901A FI980901A (sv) 1998-04-23 1998-04-23 Orala sammansättningar som kontrollerat frigör levosimendan

Country Status (38)

Country Link
US (1) US7045147B1 (sv)
EP (1) EP1071397B1 (sv)
JP (2) JP4566402B2 (sv)
KR (1) KR100960597B1 (sv)
CN (1) CN1248691C (sv)
AR (1) AR019096A1 (sv)
AT (1) ATE258425T1 (sv)
AU (1) AU756641B2 (sv)
BG (1) BG64839B1 (sv)
BR (1) BR9909869A (sv)
CA (1) CA2329234C (sv)
CO (1) CO5070607A1 (sv)
CZ (1) CZ295194B6 (sv)
DE (1) DE69914472T2 (sv)
DK (1) DK1071397T3 (sv)
EA (1) EA002829B1 (sv)
EE (1) EE04220B1 (sv)
ES (1) ES2215379T3 (sv)
FI (1) FI980901A (sv)
GE (1) GEP20032906B (sv)
HK (1) HK1034032A1 (sv)
HR (1) HRP20000704B1 (sv)
HU (1) HUP0101458A3 (sv)
ID (1) ID27987A (sv)
IL (2) IL138951A0 (sv)
MX (1) MXPA00010367A (sv)
NO (1) NO329809B1 (sv)
NZ (1) NZ507453A (sv)
PL (1) PL197447B1 (sv)
PT (1) PT1071397E (sv)
RS (1) RS49962B (sv)
SI (1) SI1071397T1 (sv)
SK (1) SK285427B6 (sv)
TR (1) TR200003102T2 (sv)
TW (1) TWI224507B (sv)
UA (1) UA68376C2 (sv)
WO (1) WO1999055305A2 (sv)
ZA (1) ZA200005632B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20011465A0 (sv) * 2001-07-04 2001-07-04 Orion Corp Ny användning av en pyridazinonderivat
NZ542303A (en) * 2003-03-14 2008-12-24 Nirmal Mulye A process for preparing sustained release tablets
FI20070521L (sv) * 2006-11-10 2008-05-11 Atacama Labs Oy Korn, tabletter och granuleringsförfarande
CN102076215A (zh) 2008-06-30 2011-05-25 托卡根公司 5-氟胞嘧啶制剂及其用途
JP2014172850A (ja) * 2013-03-07 2014-09-22 Capsugel Belgium Nv ハードカプセル製剤
CN105784895B (zh) * 2015-10-30 2018-05-22 成都欣捷高新技术开发有限公司 一种用高效液相色谱仪检测左西孟旦中杂质的方法
CA3161960A1 (en) 2019-12-16 2021-06-24 Tenax Therapeutics, Inc. Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (ph-hfpef)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU555304B2 (en) 1982-04-05 1986-09-18 Merck Sharp & Dohme Limited Stabilization of drugs in alginic acid and magnesium hydroxide granules
US4716042A (en) 1986-06-16 1987-12-29 American Home Products Corporation Stabilized coated aspirin tablets
GB8903130D0 (en) 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
GB2251615B (en) * 1991-01-03 1995-02-08 Orion Yhtymae Oy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile
US5213811A (en) * 1991-09-13 1993-05-25 Sterling Drug Inc. Oral sustained-release drug compositions
GB2266841A (en) 1992-05-06 1993-11-17 Orion Yhtymae Oy Compounds for use as anti-ischemic medicaments
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
GB9614098D0 (en) * 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan
FI973804A (sv) * 1997-09-26 1999-03-27 Orion Yhtymae Oy Orala sammansättningar av levosimendan
FI974578A (sv) * 1997-12-19 1999-06-20 Orion Yhtymae Oyj Förfarande för givande av levosimendan
FI980902A (sv) * 1998-04-23 1999-10-24 Orion Yhtymae Oyj Stabila sammansättningar av levosimendan

Also Published As

Publication number Publication date
RS49962B (sr) 2008-09-29
SK285427B6 (sk) 2007-01-04
HK1034032A1 (en) 2001-10-12
PL344078A1 (en) 2001-09-24
BR9909869A (pt) 2000-12-19
MXPA00010367A (es) 2002-06-04
EE200000617A (et) 2002-06-17
WO1999055305A3 (en) 1999-12-29
ID27987A (id) 2001-05-03
PL197447B1 (pl) 2008-03-31
ATE258425T1 (de) 2004-02-15
SK15542000A3 (sk) 2001-08-06
IL138951A0 (en) 2001-11-25
JP2002512946A (ja) 2002-05-08
CZ295194B6 (cs) 2005-06-15
FI980901A0 (sv) 1998-04-23
EE04220B1 (et) 2004-02-16
WO1999055305A2 (en) 1999-11-04
CA2329234C (en) 2008-06-10
TWI224507B (en) 2004-12-01
NO20005313D0 (no) 2000-10-20
ZA200005632B (en) 2002-01-14
ES2215379T3 (es) 2004-10-01
PT1071397E (pt) 2004-06-30
CN1301163A (zh) 2001-06-27
AU3524699A (en) 1999-11-16
AU756641B2 (en) 2003-01-16
DK1071397T3 (da) 2004-04-05
UA68376C2 (en) 2004-08-16
BG104959A (en) 2001-07-31
TR200003102T2 (tr) 2001-02-21
KR100960597B1 (ko) 2010-06-07
DE69914472T2 (de) 2004-11-11
US7045147B1 (en) 2006-05-16
HUP0101458A3 (en) 2002-05-28
KR20010071172A (ko) 2001-07-28
NO20005313L (no) 2000-11-21
GEP20032906B (en) 2003-02-25
BG64839B1 (bg) 2006-06-30
EP1071397A2 (en) 2001-01-31
CN1248691C (zh) 2006-04-05
SI1071397T1 (en) 2004-06-30
EA200001098A1 (ru) 2001-04-23
EA002829B1 (ru) 2002-10-31
HRP20000704B1 (en) 2009-11-30
YU63900A (sh) 2003-07-07
CZ20003780A3 (en) 2001-05-16
HRP20000704A2 (en) 2001-04-30
DE69914472D1 (de) 2004-03-04
AR019096A1 (es) 2001-12-26
JP4566402B2 (ja) 2010-10-20
NO329809B1 (no) 2010-12-20
NZ507453A (en) 2003-02-28
JP2010083900A (ja) 2010-04-15
CO5070607A1 (es) 2001-08-28
HUP0101458A2 (hu) 2002-03-28
IL138951A (en) 2006-10-31
EP1071397B1 (en) 2004-01-28
CA2329234A1 (en) 1999-11-04

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